Planning for the weather is a good way to make your trip to Iquitos relaxing and enjoyable, especially when you’re splurging. The hottest months are usually September and October with an average temp of 79°F, while the coldest months are July and June with an average of 77°F. The rainiest months in Iquitos are March, April, January, and December, with each month seeing an average of 14 inches of rainfall.