Isernia Vacations from $1,474

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Your Isernia Vacation

Skip the stress of planning your next great adventure with a Isernia vacation package. Whether you're here for its food, history, art or other highlights, there's an inexhaustible array of experiences to be had. If your trip to Isernia includes a little sightseeing, visit famous attractions like Basilica Minore dellAddolorata, National Museum of the Paleolithic and Cathedral of Isernia. Expedia will help you escape your daily routine. Tailor your vacation to Isernia to match your travel style, whatever that may be!

The Latest Isernia vacation packages

Price found within the past 48 hours. Click for updated prices.
Serena Majestic Hotel

Serena Majestic Hotel

4 out of 5
Price was $1,634, price is now $1,474 per person
$1,474
per person
Aug 31 - Sep 5
found 20 hours ago
Roundtrip flight included
New York (NYC) to Pescara (PSR)
7.8/10 Good! (57 reviews)
Very clean and the BLD buffet was amazing!

Reviewed on Jul 15, 2024

Hotel Adria

Hotel Adria

3 out of 5
Price was $1,915, price is now $1,776 per person
$1,776
per person
Sep 7 - Sep 12
found 1 day ago
Roundtrip flight included
Los Angeles (LAX) to Pescara (PSR)
6/10 (5 reviews)
The property is close to the sea and you can easily go for a walk along the seafront at night. Poor information at check-in and various requests not attended or had to wait more than one day. Restaurant and room service badly organized

Reviewed on Jul 22, 2021

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Stay near popular Isernia attractions

Fontana Fraterna

9.2/5 (5 reviews)
After visiting Fontana Fraterna, make a plan to see the other sights and activities in Isernia. You can enjoy the restaurants while in the area.
See properties

Isernia Hotel Deals

Central Isernia

Central Isernia

Via XXIV Maggio n. 235 Isernia IS
$74 nightly
The price is $82 total per night from Jul 10 to Jul 11
$82 total
Jul 10 - Jul 11
Total with taxes and fees
9.2/10 Wonderful! (5 reviews)
"Massima attenzione a tutte le necessità del cliente da parte del proprietario della struttura."

Reviewed on May 31, 2026

Central Isernia
Moon Resort & Spa

Moon Resort & Spa

Via G. Tedeschi, 85 Isernia IS
Get rates
Moon Resort & Spa
Best Western Hotel Rocca

Best Western Hotel Rocca

4 out of 5
Via Sferracavalli 105 Cassino FR
Fully refundableReserve now, pay when you stay
$100 nightly
The price is $114 total per night from Jul 1 to Jul 2
$114 total
Jul 1 - Jul 2
Total with taxes and fees
8.8/10 Excellent! (130 reviews)
"I would highly recommend Hotel Rocca. Great location, clean, good restaurant on site, breakfast was delucious with many options. Staff are very helpful."

Reviewed on Jun 24, 2026

Best Western Hotel Rocca
See all 339 properties in Isernia
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Isernia Vacation Packages

Isernia Essential Information

Language
Italian
Currency
Euros
Local Welcome
Ciao
Local Goodbye
Ciao
Population
16,900
Max Temp Winter
50ºF
Max Temp Summer
80ºF
Top Sights
Campitello Matese Ski Resort, Pandone Castle National Museum and Cathedral of Isernia

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Frequently asked questions

How much does an Isernia vacation package cost?
You'll find cheap prices from $1,474 on Expedia for your Isernia break. However, factors like the hotel choice, length of stay and season will influence how much your vacation to Isernia costs.
What are the cheapest months to go to Isernia?
January, April and December are the best times to search for cheap Isernia vacation packages. Traveling in quieter months means you can typically find lower prices on hotels and flights.
How many days is enough for Isernia?
Usually, a handful of days is enough to visit the main attractions during your Isernia vacation. But if you prefer to have time to relax or go on day trips, think about extending your itinerary.
Is it worth booking a vacation package to Isernia?
It's easy to see why an Isernia vacation is on the to-do list of many travelers. Major attractions like Cathedral of Isernia are just the start of things to see and do here.
How to find the best Isernia package deals?
Start your search for an Isernia package deal by entering your travel dates and destination under our "Packages" tab. Then apply some filters, like "Property type" and "Amenities," to fine-tune the results to your exact needs. You can also sort by "Package discount" and browse offers that come with irresistible savings. If you don't find the ideal Isernia package deal straight away, just tweak your dates and search again. Keep in mind that deals are only available for a limited time, so book early and get your Isernia escape off to a flying start.
Is it cheaper to book an Isernia vacation as a package?
An Expedia vacation package could land you great savings when compared to arranging flights and accommodations individually. Better still, you can personalize your Isernia getaway to fit your exact needs. Choose your preferred flight time, select the hotel type and add a rental car. Explore our bundles to see how much you can save.
When to book a vacation package to Isernia?
If you're planning an impromptu Isernia adventure, browse our last-minute deals that can be booked up to one week before you go. Prefer not to wait until the last minute? You can find terrific deals on your hotels and flights by booking well in advance.
Does Expedia offer Book Now, Pay Later Isernia vacation packages?
If you're like us, you love going away but don't love the price tag that can come with it. That's why we offer Book Now, Pay Later vacations. With the help of online lender Affirm, you can break down the overall cost of your Isernia trip across 3, 6 or 12 months. There are also no hidden or late payment fees, so you can snap up cheap vacation packages with payment plans as soon as you see them.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.