A historic square with cobblestone pavement, classic European architecture, and a clear blue sky.

Isernia Vacation Rentals

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Check prices for these dates

In two weeks
Aug 28 - Aug 30
In two months
Oct 9 - Oct 11
In three months
Nov 6 - Nov 8
In four months
Dec 4 - Dec 6

Our top choices for Isernia vacation rentals

Property grounds

1. Mimi Home.

Mimi Home.
Isernia
$117 nightly
The price is $117
Sep 10 - Sep 11
Total with taxes and fees
Mimi Home.
TV

2. Lillo Home

Lillo Home
Isernia
$186 nightly
The price is $186
Sep 10 - Sep 11
Total with taxes and fees
Lillo Home
Interior

3. Ampio Appartamento Moderno

Ampio Appartamento Moderno
Molise
8.8 out of 10, Excellent, (3 reviews)
"Town was pleasant, the owner Luca was fantastic. "
United States
frank n.
$79 nightly
The price is $79
Aug 13 - Aug 14
Total with taxes and fees
Ampio Appartamento Moderno
1 bedroom, WiFi

4. Mini Red Hub - Design Apartment Vieni a immergerti nel verde!!!

Mini Red Hub - Design Apartment Vieni a immergerti nel verde!!!
sant agapitp
$109 nightly
The price is $109
Sep 5 - Sep 6
Total with taxes and fees
Mini Red Hub - Design Apartment Vieni a immergerti nel verde!!!
Interior entrance

5. Dimora del Prete di Belmonte - Bed & Breakfast

Dimora del Prete di Belmonte - Bed & Breakfast
Venafro
9.6 out of 10, Exceptional, (35 reviews)
"This palace is a dream, beautifully appointed, stunning views and Dorothy, the owner, felt like an old friend. I wanted to stay so much longer. Only improvement would have been directions or signage on how to find the grand abode. Once found, parking was available right out front on the street, a safe street. "
United States
Paula
$92 nightly
The price is $102
Aug 13 - Aug 14
Total with taxes and fees
Dimora del Prete di Belmonte - Bed & Breakfast
Exterior detail

6. Grandfather Ludovico vacation home

Grandfather Ludovico vacation home
Roccasicura
$165 nightly
The price is $165
Aug 12 - Aug 13
Total with taxes and fees
Grandfather Ludovico vacation home
Exterior

7. BELVEDERE - Bed & Breakfast - Holiday Home

BELVEDERE - Bed & Breakfast - Holiday Home
Pozzilli
10.0 out of 10, Exceptional, (1 review)
"We came across this property by chance on our 4 week tour of southern Italy and what a find it was!The apartment is gorgeous, clean, large, well equipped and situated.It had everything we needed and a bonus was it is in the center of World War Two Winter Line, lovely little museum and French Military Cemetery.If you are visiting WW2 sites it is perfect, if you are looking for relaxation in the middle of the Italian countryside this property is for you.We stayed in 10 VRBOs on our trip and this...
United States
Grahame C.
$110 nightly
The price is $110
Aug 25 - Aug 26
Total with taxes and fees
BELVEDERE - Bed & Breakfast - Holiday Home
Interior

8. Tana dell'orso 10 - Two Bedroom House, Sleeps 4

Tana dell'orso 10 - Two Bedroom House, Sleeps 4
Castel di Sangro
Tana dell'orso 10 - Two Bedroom House, Sleeps 4
Terrace/patio

9. Anna Cerasuolo House | Whole house in mountain hamlet

Anna Cerasuolo House | Whole house in mountain hamlet
Molise
$129 nightly
The price is $129
Aug 18 - Aug 19
Total with taxes and fees
Anna Cerasuolo House | Whole house in mountain hamlet
Superior Chalet, 2 Bedrooms, Lake View | WiFi (free)

10. The Village Chalet

The Village Chalet
Castel di Sangro
$119 nightly
The price is $131
Sep 9 - Sep 10
Total with taxes and fees
The Village Chalet
Pool

11. Villa with pool, wilderness spa and star dome

Villa with pool, wilderness spa and star dome
Santa Maria del Molise
$765 nightly
The price is $765
Sep 1 - Sep 2
Total with taxes and fees
Villa with pool, wilderness spa and star dome
Pool

12. Holiday Home Tenuta Fortilù

Holiday Home Tenuta Fortilù
Santa Maria del Molise
$756 nightly
The price is $756
Aug 12 - Aug 13
Total with taxes and fees
Holiday Home Tenuta Fortilù
Dining

13. Palazzo Indaco - RESIDENZA RUBINO

Palazzo Indaco - RESIDENZA RUBINO
Castel di Sangro
$206 nightly
The price is $229
Aug 30 - Aug 31
Total with taxes and fees
Palazzo Indaco - RESIDENZA RUBINO
Property grounds

14. Daphne Estate

Daphne Estate
Aia Vecchia
6.0 out of 10, (1 review)
"It truly is a beautiful property. Know that it is significantly tucked away on a tertiary road. The host's assistants (Noemi and Corrado) are responsive and kind. We stayed during a heat wave, so the house was always warm. There are no fans and no A/C. We left the windows open at night but there are no screens on the window, so... bugs. Please request a floor fan from the host or assistants if you are traveling here during summer months. We never got one from the property owner even though we...
United States
Erik Q.
$275 nightly
The price is $314
Aug 25 - Aug 26
Total with taxes and fees
Daphne Estate
Interior

15. Largo Zeza Fifteen Holiday Home

Largo Zeza Fifteen Holiday Home
Bojano
$472 nightly
The price is $472
Aug 12 - Aug 13
Total with taxes and fees
Largo Zeza Fifteen Holiday Home
Exterior

16. Casa Delle Fate

Casa Delle Fate
Gallo Matese
$227 nightly
The price is $240
Aug 25 - Aug 26
Total with taxes and fees
Casa Delle Fate
Interior

17. Aria di Casa Experience - Independent room with private bathroom

Aria di Casa Experience - Independent room with private bathroom
Cassino
$78 nightly
The price is $80
Aug 22 - Aug 23
Total with taxes and fees
Aria di Casa Experience - Independent room with private bathroom
1 bedroom, iron/ironing board, WiFi, bed sheets

18. Cassino-two-room apartment-park rondo

Cassino-two-room apartment-park rondo
Cassino
$164 nightly
The price is $166
Sep 2 - Sep 3
Total with taxes and fees
Cassino-two-room apartment-park rondo
Exterior detail

19. Vacation Home "Residence Fonte Eremita" with Mountain View, Shared Garden & Wi-Fi

Vacation Home "Residence Fonte Eremita" with Mountain View, Shared Garden & Wi-Fi
Roccaraso
$449 nightly
The price is $453
Sep 2 - Sep 3
Total with taxes and fees
Vacation Home "Residence Fonte Eremita" with Mountain View, Shared Garden & Wi-Fi
1 bedroom, desk, iron/ironing board, WiFi

20. Cassino - Appartamento Duplex - Parco Rondo'

Cassino - Appartamento Duplex - Parco Rondo'
Cassino
2.0 out of 10, (1 review)
"We booked this property in early March 2023 for 5 days. We were coming from the USA for the first time to visit Italy. When we arrived we messaged the owner to find out what we had to do to check in. On the night before we were to arrive we received a response saying they overbooked and we would receive a full refund. WE WERE TOTALLY SHOCKED!!!! We had no place to go!!!! We called VRBO to inform them of our dilemma. They said they would try to help find another place. We quickly found our own...
United States
Joanne R.
$141 nightly
The price is $143
Sep 1 - Sep 2
Total with taxes and fees
Cassino - Appartamento Duplex - Parco Rondo'
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Isernia Hotel Reviews

Archi del Sole & San Rocco

Archi del Sole & San Rocco

10/10 Excellent
"Wonderful location right by the main square. Well maintained and very clean. However, the best part about this hotel is the people who run it. We had the best experience right from the start. Everyone was very helpful, warm, and just a joy to be around despite some language barrier. We’d happily return if we visit this area again. Thank you!"
Mark 2-night trip
Posted 1 day ago
Archi del Sole & San Rocco

Find out more about Isernia

Everything you need to know about Isernia vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Isernia vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Isernia vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Isernia vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Isernia. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Isernia in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $80 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Isernia rentals

At Expedia, we put the best Isernia vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Isernia rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Isernia vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Isernia. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Explore a world of travel with Expedia

Frequently asked questions

Can I find a vacation rental in Isernia?

Yes, we offer vacation rentals close to popular points of interest in Isernia, or you can go with a more secluded option if you want a relaxing place to stay. Isernia is known for its monuments.

What are some of the best vacation rentals that Isernia has to offer?

Retreat in the old town, Base for the Matese: This vacation home rental outside of Isernia is located in the city center and has a fireplace, a balcony, and laundry facilities to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a fridge, a stovetop, and kitchenware, so you can cook with friends or family. You and your friends and family can relax into your vacation with amenities like a selection of books.

What’s there to see and do in Isernia?

While you're exploring the area, Cipresseta di Fontegreca and Lago di Castel San Vincenzo are a couple of picturesque spots to get outside and enjoy nature. Cathedral of Isernia and National Museum of the Paleolithic are other places to visit while you're in town.

What’s a vacation rental in Isernia like?

A vacation rental is a private property you can book for several days or longer in Isernia. Vacation rentals feature amenities like kitchens and laundry facilities so you'll have a home away from home. If you're concerned about a clean environment, a vacation rental can offer a sense of safety away from shared hotel elevators and busy lobbies while still allowing you the experience of travel. You'll also get more space in a vacation rental than in a standard hotel, which makes a vacation rental a popular choice for family trips or small group gatherings.