Title: Salsipuedes Vacation Rentals from $102: Search Short-Term Rentals | Expedia.com [Hotels in Salsipuedes](https://expedia.com/Salsipuedes-Hotels.d553248635975870060.Travel-Guide-Hotels)[Car Rentals in Salsipuedes](https://expedia.com/Car-Rentals-In-Salsipuedes.d553248635975870060.Car-Rental-Guide)[Salsipuedes Vacation Packages](https://expedia.com/Salsipuedes.d553248635975870060.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/32a5a1b7-682e-4c22-a8ab-4b736795e0ea/expedia_fallback.webp?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/32a5a1b7-682e-4c22-a8ab-4b736795e0ea/expedia_fallback.webp?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light_bundle_and_save.svg) ### Bundle & Save Get more, spend less whenever you see Bundle & Save deals - ![](https://a.travel-assets.com/travel-assets-manager/pictograms-expedia/light__onekey.svg) ### OneKeyCash Earn OneKeyCash on all your eligible bookings - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light_ftc.svg) ### Upfront pricing We are not like the others - we include taxes and fees ## Check prices for these dates In two weeks [Apr 10 - Apr 12](https://www.expedia.com/Hotel-Search?regionId=553248635975870060&startDate=2026-04-10&endDate=2026-04-12&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [May 22 - May 24](https://www.expedia.com/Hotel-Search?regionId=553248635975870060&startDate=2026-05-22&endDate=2026-05-24&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In three months [Jun 19 - Jun 21](https://www.expedia.com/Hotel-Search?regionId=553248635975870060&startDate=2026-06-19&endDate=2026-06-21&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In four months [Jul 17 - Jul 19](https://www.expedia.com/Hotel-Search?regionId=553248635975870060&startDate=2026-07-17&endDate=2026-07-19&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Salsipuedes vacation rentals ![Outdoor pool](https://images.trvl-media.com/lodging/92000000/91500000/91495500/91495486/b12b577d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop terrace](https://images.trvl-media.com/lodging/92000000/91500000/91495500/91495486/2fdde3f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (17B) | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/92000000/91500000/91495500/91495486/4bc61653.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (17B) | Living area | 32-inch Smart TV with digital channels, TV](https://images.trvl-media.com/lodging/92000000/91500000/91495500/91495486/f99400a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Boutique Apartments Atlapa [](https://www.expedia.com/Panama-City-Hotels-Boutique-Apartments-Atlapa.h91495486.Hotel-Information) San Francisco 7.6/10 Good (35 reviews) "The place was clean nice an its comfortable an the view is to kill for amazing ‼️" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Odaine $133 nightly $146 total Mar 30 - Mar 31 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Boutique-Apartments-Atlapa.h91495486.Hotel-Information) ![Apartment, 3 Bedrooms | Living area | 32-inch Smart TV with digital channels, TV, Netflix](https://images.trvl-media.com/lodging/89000000/88680000/88675400/88675323/4fefbf57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/89000000/88680000/88675400/88675323/6445192b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 3 Bedrooms | Individually decorated, individually furnished, laptop workspace](https://images.trvl-media.com/lodging/89000000/88680000/88675400/88675323/c45dedaa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 3 Bedrooms | Television](https://images.trvl-media.com/lodging/89000000/88680000/88675400/88675323/e5394f26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Boutique Apartments Panamá Coco del Mar [](https://www.expedia.com/Panama-City-Hotels-Boutique-Apartments-Panama-Coco-Del-Mar.h88675323.Hotel-Information) San Francisco 7.6/10 Good (176 reviews) "The best place " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Julio $178 nightly $195 total Apr 1 - Apr 2 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Boutique-Apartments-Panama-Coco-Del-Mar.h88675323.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/79000000/78290000/78283500/78283415/362ba912.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | Balcony](https://images.trvl-media.com/lodging/79000000/78290000/78283500/78283415/97c51ab9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/79000000/78290000/78283500/78283415/a4be5f58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-size fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/79000000/78290000/78283500/78283415/737ceca4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Boutique Apartments Panama [](https://www.expedia.com/Panama-City-Hotels-Boutique-Apartments-Panama.h78283415.Hotel-Information) Bella Vista 7.6/10 Good (267 reviews) "Great central location! Great price. Clean. Nice pool." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Armin $129 nightly $141 total Mar 30 - Mar 31 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Boutique-Apartments-Panama.h78283415.Hotel-Information) ![TV](https://images.trvl-media.com/lodging/123000000/122660000/122657100/122657050/87d5a99d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/123000000/122660000/122657100/122657050/be270857.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gym](https://images.trvl-media.com/lodging/123000000/122660000/122657100/122657050/1cbda3e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/123000000/122660000/122657100/122657050/c9888658.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Living 73 Panamá by Boutique Apartments [](https://www.expedia.com/Panama-City-Hotels-Living-73.h122657050.Hotel-Information) San Francisco $158 nightly $189 total Mar 30 - Mar 31 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Living-73.h122657050.Hotel-Information) ![50-inch LED TV with satellite channels](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/81757b88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/bba49e63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining room](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/dbfbf214.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![50-inch LED TV with satellite channels](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/dc088c7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Arcadia Condo Suites [](https://www.expedia.com/Panama-City-Hotels-Arcadia-Condo-Suites.h104456900.Hotel-Information) Costa del Este 9.4/10 Exceptional (247 reviews) "The stay was wonderful and seamless they are very friendly and efficient as always" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Clifford $162 nightly $178 total Mar 26 - Mar 27 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Arcadia-Condo-Suites.h104456900.Hotel-Information) ![Apartment, 1 Bedroom, Balcony | Property grounds](https://images.trvl-media.com/lodging/121000000/120200000/120194500/120194409/60c2353e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 1 Bedroom, Balcony | Interior](https://images.trvl-media.com/lodging/121000000/120200000/120194500/120194409/fac0c7cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 1 Bedroom, Balcony | Interior](https://images.trvl-media.com/lodging/121000000/120200000/120194500/120194409/c6afccbb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 1 Bedroom, Balcony | Dining](https://images.trvl-media.com/lodging/121000000/120200000/120194500/120194409/65d48e93.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Swette Love 10 Minutes From the Airport Tocumen [](https://www.expedia.com/Las-Mananitas-Hotels-Swette-Love-10-Minutes-From-The-Airport-Tocumen.h120194409.Hotel-Information) Las Mañanitas $70 nightly $75 total Apr 12 - Apr 13 Total with taxes and fees [](https://www.expedia.com/Las-Mananitas-Hotels-Swette-Love-10-Minutes-From-The-Airport-Tocumen.h120194409.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/5000000/4810000/4801200/4801186/24a7280d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, 2 Double Beds, Non Smoking, Connecting Rooms | Premium bedding, in-room safe, individually decorated](https://images.trvl-media.com/lodging/5000000/4810000/4801200/4801186/da2b9bed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, 1 King Bed, Non Smoking, Connecting Rooms | Premium bedding, in-room safe, individually decorated](https://images.trvl-media.com/lodging/5000000/4810000/4801200/4801186/d9012efa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/5000000/4810000/4801200/4801186/765b1a36.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Las Clementinas [](https://www.expedia.com/Panama-City-Hotels-Las-Clementinas.h4801186.Hotel-Information) Casco Viejo 9.4/10 Exceptional (183 reviews) "Best of the best, as always!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rebecca $129 nightly $142 total Apr 7 - Apr 8 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Las-Clementinas.h4801186.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/10000000/9680000/9675200/9675133/1012405e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sundeck](https://images.trvl-media.com/lodging/10000000/9680000/9675200/9675133/03c049bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/10000000/9680000/9675200/9675133/c0384242.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Suite, 2 Double Beds | Living area | Flat-screen TV](https://images.trvl-media.com/lodging/10000000/9680000/9675200/9675133/871ef81e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Torres de Alba Hotel & Suites [](https://www.expedia.com/Panama-City-Hotels-Torres-De-Alba-Hotel-Suites.h9675133.Hotel-Information) Bella Vista 8.8/10 Excellent (527 reviews) "Very clean and amazing stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Reinaldo $92 nightly $102 total Mar 30 - Mar 31 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Torres-De-Alba-Hotel-Suites.h9675133.Hotel-Information) ![Comfort Suite, 1 Queen Bed with Sofa bed | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/123000000/122150000/122140800/122140766/bbe5d86c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Towels, soap, toilet paper](https://images.trvl-media.com/lodging/123000000/122150000/122140800/122140766/53efba5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Microwave, coffee/tea maker, cookware/dishes/utensils](https://images.trvl-media.com/lodging/123000000/122150000/122140800/122140766/6bfa829b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Suite | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/123000000/122150000/122140800/122140766/9f96d68a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Palma Aparta Suite [](https://www.expedia.com/Panama-City-Hotels-La-Palma-Aparta-Suite.h122140766.Hotel-Information) Amador 8.4/10 Very Good (7 reviews) "All ways clean and ready to used ,no buddy " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alberto $80 nightly $88 total Apr 22 - Apr 23 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-La-Palma-Aparta-Suite.h122140766.Hotel-Information) ![Apartment | Living area](https://images.trvl-media.com/lodging/114000000/113060000/113058500/113058427/c0e07415.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/114000000/113060000/113058500/113058427/375f6530.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | Living area](https://images.trvl-media.com/lodging/114000000/113060000/113058500/113058427/601ad506.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | Living area](https://images.trvl-media.com/lodging/114000000/113060000/113058500/113058427/4d9b3d57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Centriqo by Wynwood house [](https://www.expedia.com/Veracruz-Hotels-Centriqo-By-Wynwood-House.h113058427.Hotel-Information) Veracruz $167 nightly $183 total Apr 19 - Apr 20 Total with taxes and fees [](https://www.expedia.com/Veracruz-Hotels-Centriqo-By-Wynwood-House.h113058427.Hotel-Information) ![Interior detail](https://images.trvl-media.com/lodging/16000000/15980000/15979000/15978996/2453d7ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Double Room | View from room](https://images.trvl-media.com/lodging/16000000/15980000/15979000/15978996/c6d0b885.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Double Queen Suite | Premium bedding, in-room safe, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/16000000/15980000/15979000/15978996/db18ada2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Suite, Annex Building (King) | Living area | 42-inch flat-screen TV with digital channels, TV](https://images.trvl-media.com/lodging/16000000/15980000/15979000/15978996/6f5654fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Isabela Suites [](https://www.expedia.com/Panama-City-Hotels-La-Isabela-Suites.h15978996.Hotel-Information) Casco Viejo 10/10 Exceptional (186 reviews) "Staying and active in rural Boquete Panama is both a treat and a retreat of relaxation." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jerry $147 nightly $164 total Apr 13 - Apr 14 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-La-Isabela-Suites.h15978996.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/111000000/110790000/110785700/110785630/7fec4ade.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Apartment | Terrace/patio](https://images.trvl-media.com/lodging/111000000/110790000/110785700/110785630/7d5bd8ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/111000000/110790000/110785700/110785630/c6184862.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Apartment | Living area | Smart TV](https://images.trvl-media.com/lodging/111000000/110790000/110785700/110785630/2f5f574e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Yoo Panamá by Boutique Apartments [](https://www.expedia.com/Panama-City-Hotels-Yoo-Panama-By-Boutique-Apartments.h110785630.Hotel-Information) Bella Vista 8.0/10 Very Good (74 reviews) "Great Apartment clean, excellent ocean view. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John $216 nightly $223 total Apr 1 - Apr 2 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Yoo-Panama-By-Boutique-Apartments.h110785630.Hotel-Information) ![Apartment | 2 bedrooms, Internet](https://images.trvl-media.com/lodging/125000000/124560000/124557900/124557851/6a3c89e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | 2 bedrooms, Internet](https://images.trvl-media.com/lodging/125000000/124560000/124557900/124557851/c37bd856.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | 2 bedrooms, Internet](https://images.trvl-media.com/lodging/125000000/124560000/124557900/124557851/37ba14ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | 2 bedrooms, Internet](https://images.trvl-media.com/lodging/125000000/124560000/124557900/124557851/cd2b03a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### w Engaging 2BR in Casco Viejo [](https://www.expedia.com/Panama-City-Hotels-W-Engaging-2BR-In-Casco-Viejo.h124557851.Hotel-Information) Casco Viejo [](https://www.expedia.com/Panama-City-Hotels-W-Engaging-2BR-In-Casco-Viejo.h124557851.Hotel-Information) ![Apartment (11G) | Living room | Heated floors](https://images.trvl-media.com/lodging/112000000/111350000/111348600/111348561/dcaddcd7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (13J) | Living area | Heated floors](https://images.trvl-media.com/lodging/112000000/111350000/111348600/111348561/w1788h1200x0y0-a490f57d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (24D) | Laundry](https://images.trvl-media.com/lodging/112000000/111350000/111348600/111348561/6d2627e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (17C) | Balcony](https://images.trvl-media.com/lodging/112000000/111350000/111348600/111348561/48b1ae26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Gray by Wynwood House [](https://www.expedia.com/Panama-City-Hotels-The-Gray-By-Wynwood-House.h111348561.Hotel-Information) Bella Vista $179 nightly $198 total Apr 6 - Apr 7 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-The-Gray-By-Wynwood-House.h111348561.Hotel-Information) ![Apartment (14D) | Dining room](https://images.trvl-media.com/lodging/118000000/117470000/117462500/117462452/2a0412bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (14D) | Soundproofing, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/118000000/117470000/117462500/117462452/422dd5ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (11F) | Living area](https://images.trvl-media.com/lodging/118000000/117470000/117462500/117462452/3115996f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (5B) | Living area](https://images.trvl-media.com/lodging/118000000/117470000/117462500/117462452/b89161f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Mini Design By Wynwood House [](https://www.expedia.com/Panama-City-Hotels-Mini-Design-By-Wynwood-House.h117462452.Hotel-Information) Bella Vista $219 nightly $241 total Apr 6 - Apr 7 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Mini-Design-By-Wynwood-House.h117462452.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/95000000/94630000/94627400/94627351/7731b155.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/95000000/94630000/94627400/94627351/b23e7852.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![32-inch TV with cable channels](https://images.trvl-media.com/lodging/95000000/94630000/94627400/94627351/24c4ebfd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room dining](https://images.trvl-media.com/lodging/95000000/94630000/94627400/94627351/5ace70c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Yoo Apartamento [](https://www.expedia.com/Panama-City-Hotels-Yoo-Apartamento.h94627351.Hotel-Information) Bella Vista 9.2/10 Wonderful (17 reviews) "Great location" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jimmy Lee $128 nightly $141 total Apr 22 - Apr 23 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Yoo-Apartamento.h94627351.Hotel-Information) ![Apartment, 2 Bedrooms (CC2A) | Premium bedding, soundproofing, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/100000000/99230000/99229300/99229225/a1353e56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (CC2B) | Living area | 100-inch Smart TV with satellite channels](https://images.trvl-media.com/lodging/100000000/99230000/99229300/99229225/86dc292b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (CC4A) | Balcony](https://images.trvl-media.com/lodging/100000000/99230000/99229300/99229225/90de29d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (CC1B) | Living area | 100-inch Smart TV with satellite channels](https://images.trvl-media.com/lodging/100000000/99230000/99229300/99229225/w2000h1310x0y0-5cea16ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa Contemporanea by Wynwood House [](https://www.expedia.com/Panama-City-Hotels-Casa-Mallet-By-Wynwood-House.h99229225.Hotel-Information) Casco Viejo 8.2/10 Very Good (21 reviews) "Cute place, well located. " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Stephanie $157 nightly $170 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Casa-Mallet-By-Wynwood-House.h99229225.Hotel-Information) ![Outdoor pool, open 7:00 AM to 10:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/w846h1318x0y4-5df5c378.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Apartment | Balcony](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/ee1ac3ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (705) | Balcony](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/ba5a7e97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business center](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/762cceb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casco View Apartments [](https://www.expedia.com/Panama-City-Hotels-Casco-View-Apartments.h102803573.Hotel-Information) Santa Ana 9.0/10 Wonderful (81 reviews) "I would definitely stay here again! The immediate surrounding neighborhood is a little run down, but it’s much better only a few blocks over. The property itself is still really nice and its really convenient walk to Casco Viejo. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kelsey $114 nightly $125 total Mar 26 - Mar 27 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Casco-View-Apartments.h102803573.Hotel-Information) ![Apartment, 2 Bedrooms (1B) | Living area | 40-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/107000000/106100000/106093500/106093420/9e77777b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2D) | Private kitchen | Coffee/tea maker, electric kettle](https://images.trvl-media.com/lodging/107000000/106100000/106093500/106093420/04577a21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (1C) | Living area | 40-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/107000000/106100000/106093500/106093420/7717b8f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (1D) | Premium bedding, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/107000000/106100000/106093500/106093420/3f9c0f41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa Love by Wynwood House [](https://www.expedia.com/Panama-City-Hotels-Casa-Love-By-Wynwood-House.h106093420.Hotel-Information) Casco Viejo 9.0/10 Wonderful (24 reviews) "Large, clean rooms, lots of space. Great bathroom. Great location. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joette $103 nightly $114 total Apr 6 - Apr 7 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Casa-Love-By-Wynwood-House.h106093420.Hotel-Information) ![Apartment (1D) | Living area | 40-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/105000000/104150000/104145400/104145345/c78eb228.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (3C) | Living area | 40-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/105000000/104150000/104145400/104145345/5b122387.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (3D) | Private kitchen | Fridge, microwave, oven, dishwasher](https://images.trvl-media.com/lodging/105000000/104150000/104145400/104145345/bf9924b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2D) | Living area | 40-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/105000000/104150000/104145400/104145345/569ccb37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa La Costa By Wynwood House [](https://www.expedia.com/Panama-City-Hotels-Casa-La-Costa-By-Wynwood-House.h104145345.Hotel-Information) Casco Viejo 8.4/10 Very Good (26 reviews) "Great location. At the border of renovated areas but an extremely go deal for this great property. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) William $116 nightly $128 total Apr 1 - Apr 2 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Casa-La-Costa-By-Wynwood-House.h104145345.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-04-08&endDate=2026-04-09®ionId=553248635975870060&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true) ## Find vacation rentals that suit your style Cabins [](https://www.expedia.com/Hotel-Search?destination=Salsipuedes%2C+Panam%C3%A1+Province%2C+Panama®ionId=553248635975870060&latLong=9.06667%2C-79.416702&adults=2&startDate=2026-06-22&d1=2026-06-22&endDate=2026-06-25&d2=2026-06-25&lodging=CABIN) Villas [](https://www.expedia.com/Hotel-Search?destination=Salsipuedes%2C+Panam%C3%A1+Province%2C+Panama®ionId=553248635975870060&latLong=9.06667%2C-79.416702&adults=2&startDate=2026-06-22&d1=2026-06-22&endDate=2026-06-25&d2=2026-06-25&lodging=VILLA) Aparthotels [](https://www.expedia.com/Hotel-Search?destination=Salsipuedes%2C+Panam%C3%A1+Province%2C+Panama®ionId=553248635975870060&latLong=9.06667%2C-79.416702&adults=2&startDate=2026-06-22&d1=2026-06-22&endDate=2026-06-25&d2=2026-06-25&lodging=APART_HOTEL) Private vacation homes [](https://www.expedia.com/Hotel-Search?destination=Salsipuedes%2C+Panam%C3%A1+Province%2C+Panama®ionId=553248635975870060&latLong=9.06667%2C-79.416702&adults=2&startDate=2026-06-22&d1=2026-06-22&endDate=2026-06-25&d2=2026-06-25&lodging=VACATION_HOME) Condos [](https://www.expedia.com/Hotel-Search?destination=Salsipuedes%2C+Panam%C3%A1+Province%2C+Panama®ionId=553248635975870060&latLong=9.06667%2C-79.416702&adults=2&startDate=2026-06-22&d1=2026-06-22&endDate=2026-06-25&d2=2026-06-25&lodging=CONDO) Apartments [](https://www.expedia.com/Hotel-Search?destination=Salsipuedes%2C+Panam%C3%A1+Province%2C+Panama®ionId=553248635975870060&latLong=9.06667%2C-79.416702&adults=2&startDate=2026-06-22&d1=2026-06-22&endDate=2026-06-25&d2=2026-06-25&lodging=APARTMENT) Cottages [](https://www.expedia.com/Hotel-Search?destination=Salsipuedes%2C+Panam%C3%A1+Province%2C+Panama®ionId=553248635975870060&latLong=9.06667%2C-79.416702&adults=2&startDate=2026-06-22&d1=2026-06-22&endDate=2026-06-25&d2=2026-06-25&lodging=COTTAGE) Houseboats [](https://www.expedia.com/Hotel-Search?destination=Salsipuedes%2C+Panam%C3%A1+Province%2C+Panama®ionId=553248635975870060&latLong=9.06667%2C-79.416702&adults=2&startDate=2026-06-22&d1=2026-06-22&endDate=2026-06-25&d2=2026-06-25&lodging=HOUSE_BOAT) Chalets [](https://www.expedia.com/Hotel-Search?destination=Salsipuedes%2C+Panam%C3%A1+Province%2C+Panama®ionId=553248635975870060&latLong=9.06667%2C-79.416702&adults=2&startDate=2026-06-22&d1=2026-06-22&endDate=2026-06-25&d2=2026-06-25&lodging=CHALET) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSalsipuedes-Vacation-Rentals.d553248635975870060.Travel-Guide-VacationRentals)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSalsipuedes-Vacation-Rentals.d553248635975870060.Travel-Guide-VacationRentals) ## Top Salsipuedes Hotel Reviews ![Hotel Ojos del Rio](https://images.trvl-media.com/lodging/11000000/10540000/10538500/10538417/dddd2643_y.jpg) ### Hotel Ojos del Rio 4/10 Poor "A run down property, poorly maintained. The gym is dirty with 1 bumbell of each weight no pairs, staff barely understands english. Room attendant did a good job. Breakfast was OK and really why i booked here. A real 2 star spot. " [](https://expedia.com/Panama-City-Hotels-Hotel-Ojos-Del-Rio.h10538417.Hotel-Information) ![Courtyard by Marriott Panama Multiplaza Mall](https://images.trvl-media.com/lodging/2000000/1150000/1145700/1145666/7dd302e1_y.jpg) ### Courtyard by Marriott Panama Multiplaza Mall 8/10 Good "Clean room. Nice king sized bed. Water view, no balcony. Bar fridge. Clean bathroom and shower. Adequate bath and hand towels. Might sound strange to mention but there were face cloths here while they were none in 2 other properties we stayed in while in Panama city. Large desk. Some english tv channels. Room and building A/C functioned and quiet. Room was quiet except for occasional hallway noise. Only real negative was the black streak the trailed from the a/c vent. Excellent front desk staff that are fluent english speakers. Check in and check out were fast and painless. Taxi service available in the lobby. Attached to a very large and modern shopping mall." [](https://expedia.com/Panama-City-Hotels-Courtyard-By-Marriott-Panama-Multiplaza-Mall.h1145666.Hotel-Information) ![W Panama](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/5dc0b3d1_y.jpg) ### W Panama 10/10 Excellent "5star for sure !!" [](https://expedia.com/Panama-City-Hotels-W-Panama.h21314035.Hotel-Information) ![Ramada Plaza by Wyndham Panama Punta Pacifica](https://images.trvl-media.com/lodging/9000000/8220000/8217000/8216939/7d8fcf8b_y.jpg) ### Ramada Plaza by Wyndham Panama Punta Pacifica 10/10 Excellent "The room was very nice, air conditioning worked well, great area close to shopping mall " [](https://expedia.com/Panama-City-Hotels-Ramada-Plaza-By-Wyndham-Panama-Punta-Pacifica.h8216939.Hotel-Information) ![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/6f5f0f4f_y.jpg) ### Hotel Riu Plaza Panama 10/10 Excellent "The hotel stay was good overall, the breakfast was excellent but I had one complaint. There was no coffee machine in the room, and when I reported it to the front desk, it was not addressed." [](https://expedia.com/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information) ![Hotel El Panama by Faranda Grand, a member of Radisson Individuals](https://images.trvl-media.com/lodging/1000000/10000/7200/7164/cfc3400a_y.jpg) ### Hotel El Panama by Faranda Grand, a member of Radisson Individuals 10/10 Excellent "Nice place for an older hotel. Had fun seeing a pro boxing fight walking distance from Hotel" [](https://expedia.com/Panama-City-Hotels-Hotel-El-Panama-By-Faranda-Grand.h7164.Hotel-Information) ![The Executive Hotel](https://images.trvl-media.com/lodging/1000000/530000/522100/522086/e3ee3bd7_y.jpg) ### The Executive Hotel 10/10 Excellent "Excellent hotel and great staff - everybody from the front desk to the restaurant staff to especially the housekeepers really make this hotel so comfortable and welcoming. The rooms & entire property are updated, clean & very comfortable. The location is central, perfect to explore by foot or short taxi rides, and has bars/restaurants, grocery & convenience stores within easy walking distance. We had a suite this time and, wow, it will be hard to go back to a regular room." [](https://expedia.com/Panama-City-Hotels-The-Executive-Hotel.h522086.Hotel-Information) ![Crowne Plaza Panama Airport by IHG](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/877d081d_y.jpg) ### Crowne Plaza Panama Airport by IHG 10/10 Excellent "Clean room / staff / airport shuttle / outdoor pool" [](https://expedia.com/Tocumen-Hotels-Crowne-Plaza-Panama-Airport.h8836117.Hotel-Information) ![The Westin Playa Bonita Panama](https://images.trvl-media.com/lodging/5000000/4670000/4668700/4668643/e50f6f0f_y.jpg) ### The Westin Playa Bonita Panama 8/10 Good "Overall, the property and staff were amazing, friendly, attentive, and always willing to help. The grounds & hotel were beautiful and well-kept, and we especially enjoyed the live entertainment each night. However, some parts of the stay didn’t meet expectations. The excursions and activities booked through the property were quite expensive, and we didn’t feel they matched the value for what we paid. A recurring issue during our stay was the in-room TV, it displayed another guest’s name and room number. Despite visiting the front desk multiple times and having maintenance come by, the issue was never resolved. This was concerning since the TV shows billing details and messages. Restaurant options were limited, and while the food was delicious, portions were small and meals pricey, often around $75 or more for two without alcohol. Most staff members spoke limited English, so communication could be tricky at times. Washcloths weren’t provided automatically, we had to request them. The pool closes when the sun sets and reopens only after morning cleaning, so swimming hours are limited. Be sure to use the mosquito wipes provided, those little things are sneaky and persistent! If you’re not fluent in Spanish, I wouldn’t recommend driving, most road signs & directions are all in Spanish, and driving customs differ from the U.S. Despite the hiccups, the service, scenery, and local charm made the trip memorable especially seeing traffic stop completely to let a sloth cross the road!" [](https://expedia.com/Panama-City-Hotels-The-Westin-Playa-Bonita-Panama.h4668643.Hotel-Information) ## Find out more about Salsipuedes **Everything you need to know about Salsipuedes vacation rentals** Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Salsipuedes vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on. There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Salsipuedes vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search. **Salsipuedes vacation rentals: An excellent choice for every season** Whenever you want to travel, a warm welcome awaits you in Salsipuedes. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Salsipuedes in high season. Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $102 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals! **How to find incredible deals on Salsipuedes rentals** At Expedia, we put the best Salsipuedes vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. To find some top Salsipuedes rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Salsipuedes vacation. If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Salsipuedes. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence. ## Explore a world of travel with Expedia - Trending destinations on Expedia.com ### Trending destinations on Expedia.com - [Destin Vacation Rentals ](https://www.expedia.com/Destin-Vacation-Rentals.d6906.Travel-Guide-VacationRentals) - [Panama City Vacation Rentals ](https://www.expedia.com/Panama-City-Beach-Vacation-Rentals.d8021.Travel-Guide-VacationRentals) - [Hilton Head Vacation Rentals ](https://www.expedia.com/Hilton-Head-Island-Vacation-Rentals.d601684.Travel-Guide-VacationRentals) - [Gulf Shores Vacation Rentals ](https://www.expedia.com/Gulf-Shores-Vacation-Rentals.d603078.Travel-Guide-VacationRentals) - [Key West Vacation Rentals ](https://www.expedia.com/Key-West-Vacation-Rentals.d1187.Travel-Guide-VacationRentals) - [Gatlinburg Vacation Rentals ](https://www.expedia.com/Gatlinburg-Vacation-Rentals.d7474.Travel-Guide-VacationRentals) - [Maui Vacation Rentals ](https://www.expedia.com/Maui-Vacation-Rentals.d180073.Travel-Guide-VacationRentals) - [Orlando Vacation Rentals ](https://www.expedia.com/Orlando-Vacation-Rentals.d178294.Travel-Guide-VacationRentals) - [Myrtle Beach Vacation Rentals ](https://www.expedia.com/Myrtle-Beach-Vacation-Rentals.d601685.Travel-Guide-VacationRentals) - [Orange Beach Vacation Rentals ](https://www.expedia.com/Orange-Beach-Vacation-Rentals.d9136.Travel-Guide-VacationRentals) - [Pigeon Forge Vacation Rentals ](https://www.expedia.com/Pigeon-Forge-Vacation-Rentals.d8264.Travel-Guide-VacationRentals) - [Ocean City Vacation Rentals ](https://www.expedia.com/Ocean-City-Vacation-Rentals.d9151.Travel-Guide-VacationRentals) - [Outer Banks Vacation Rentals ](https://www.expedia.com/Outer-Banks-Vacation-Rentals.d602135.Travel-Guide-VacationRentals) - [San Diego Vacation Rentals ](https://www.expedia.com/San-Diego-Vacation-Rentals.d3073.Travel-Guide-VacationRentals) - [Siesta Key Vacation Rentals ](https://www.expedia.com/Siesta-Key-Vacation-Rentals.d6881.Travel-Guide-VacationRentals) - [Galveston Vacation Rentals ](https://www.expedia.com/Galveston-Vacation-Rentals.d1341.Travel-Guide-VacationRentals) - [Clearwater Beach Vacation Rentals ](https://www.expedia.com/Clearwater-Beach-Vacation-Rentals.d10759.Travel-Guide-VacationRentals) - [Palm Springs Vacation Rentals ](https://www.expedia.com/Palm-Springs-Vacation-Rentals.d180676.Travel-Guide-VacationRentals) - [Florida Keys Vacation Rentals ](https://www.expedia.com/Florida-Keys-Vacation-Rentals.d6023765.Travel-Guide-VacationRentals) - [Lake Tahoe Vacation Rentals ](https://www.expedia.com/South-Lake-Tahoe-Vacation-Rentals.d10150.Travel-Guide-VacationRentals) - [Lake of the Ozarks Vacation Rentals ](https://www.expedia.com/Lake-Ozark-Vacation-Rentals.d177772.Travel-Guide-VacationRentals) - [Florida Vacation Rentals ](https://www.expedia.com/Destinations-In-Florida.d211.Vacation-Rental-Destinations) - [Hawaii Vacation Rentals ](https://www.expedia.com/Destinations-In-Hawaii.d213.Vacation-Rental-Destinations) - [Michigan Vacation Rentals ](https://www.expedia.com/Destinations-In-Michigan.d224.Vacation-Rental-Destinations) ## Frequently asked questions ### Can I find vacation rentals in Salsipuedes? ### What are some of the best vacation rentals that Salsipuedes has to offer? ### How many vacation rentals will I find in Salsipuedes? ### What’s there to see and do in Salsipuedes? ### What’s a vacation rental in Salsipuedes like? ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save even more - get up to 20% on select hotels when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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