Vacation Rentals in Panama

Start date: Check-in selected.
To Date
End date: Check-out
  • Bundle & Save

    Get more, spend less whenever you see Bundle & Save deals
  • OneKeyCash

    Earn OneKeyCash on all your eligible bookings
  • Upfront pricing

    We are not like the others - we include taxes and fees

Top Cities in Panama

Our top choices for Panama vacation rentals

Villa Alejandro

Villa Alejandro
3.5 star property
Boquete
8.8 out of 10, Excellent, (130)
"Priced right, easy walk to town, safe, quiet & overall great stay! "
United States
John
$77 nightly
The price is $86
Dec 26 - Dec 27
Total with taxes and fees
Villa Alejandro

Boutique Apartments Panama

Boutique Apartments Panama
3.5 star property
Bella Vista
7.6 out of 10, Good, (221)
"The view was amazing and the place was great could stay here again "
United States
Yonnette
$121 nightly
The price is $133
Jan 4 - Jan 5, 2026
Total with taxes and fees
Boutique Apartments Panama

Arcadia Condo Suites

Arcadia Condo Suites
2.5 star property
Costa del Este
9.4 out of 10, Exceptional, (167)
"Everything was great, helpful staff, great room , clean, excellent service!"
United States
Gregory Walter
$117 nightly
The price is $129
Jan 2 - Jan 3, 2026
Total with taxes and fees
Arcadia Condo Suites

Las Clementinas

Las Clementinas
3.5 star property
Casco Viejo
9.4 out of 10, Exceptional, (171)
"The front desk receptionist was extremely helpful! The room was clean and comfortable! We would definitely stay again!"
United States
april
$159 nightly
The price is $175
Jan 13 - Jan 14, 2026
Total with taxes and fees
Las Clementinas

Torres de Alba Hotel & Suites

Torres de Alba Hotel & Suites
3.5 star property
Bella Vista
8.8 out of 10, Excellent, (483)
"The buffet bar and great customer service. "
United States
Kayhiuska
$92 nightly
The price is $102
Dec 25 - Dec 26
Total with taxes and fees
Torres de Alba Hotel & Suites

Sun Havens Apartments & Suites

Sun Havens Apartments & Suites
3.0 star property
Bocas del Toro
8.4 out of 10, Very Good, (67)
"Great place and even better people! The room was clean, comfortable and the kitchen was well equipped. The location was great as well as it was only a short walk to everything including the airport. I will definitely stay here again. "
United States
James
$31 nightly
The price is $34
Dec 28 - Dec 29
Total with taxes and fees
Sun Havens Apartments & Suites

La Palma Aparta Suite

La Palma Aparta Suite
3.0 star property
Amador
$75 nightly
The price is $82
Dec 25 - Dec 26
Total with taxes and fees
La Palma Aparta Suite

La Isabela Suites

La Isabela Suites
3.5 star property
Casco Viejo
10.0 out of 10, Exceptional, (171)
"Wonderful charming property in the heart of the historic district. "
United States
Angela
$163 nightly
The price is $181
Jan 6 - Jan 7, 2026
Total with taxes and fees
La Isabela Suites

Yoo Panamá by Boutique Apartments

Yoo Panamá by Boutique Apartments
3.5 star property
Bella Vista
8.2 out of 10, Very Good, (49)
"Nice view & very clean"
United States
Latricia
$183 nightly
The price is $188
Dec 30 - Dec 31
Total with taxes and fees
Yoo Panamá by Boutique Apartments

Casa Mate by Villa Alejandro

Casa Mate by Villa Alejandro
3.5 star property
Los Naranjos
$104 nightly
The price is $114
Jan 7 - Jan 8, 2026
Total with taxes and fees
Casa Mate by Villa Alejandro

Peace N' Green

Peace N' Green
3.0 star property
David
$47 nightly
The price is $52
Dec 27 - Dec 28
Total with taxes and fees
Peace N' Green

Aires frescos de Boquete

Aires frescos de Boquete
2.0 star property
Alto Boquete
9.0 out of 10, Wonderful, (4)
"I stayed there for 13 nights during a move to Panama. A real nice family run business. It was a great experience. The property is very well kept and super clean. The staff was super friendly and very timely with any questions I had. I had a small efficiency and there is a nice grocery store one block away. Can’t say enough and I would certainly recommend AIRES FRESCO to my friends and family. "
United States
David
$50 nightly
The price is $55
Dec 28 - Dec 29
Total with taxes and fees
Aires frescos de Boquete

Habitación Privada en Playa Dorada + Kitchenette

Habitación Privada en Playa Dorada + Kitchenette
3.0 star property
Vacamonte
$33 nightly
The price is $36
Dec 25 - Dec 26
Total with taxes and fees
Habitación Privada en Playa Dorada + Kitchenette

Yoo Panama & Arts Tower

Yoo Panama & Arts Tower
3.0 star property
Bella Vista
9.6 out of 10, Exceptional, (52)
"Ron was amazing and so was the property!"
United States
John
$186 nightly
The price is $205
Jan 2 - Jan 3, 2026
Total with taxes and fees
Yoo Panama & Arts Tower

Punta Chame Club and Resort

Punta Chame Club and Resort
4.0 star property
Pajonal
9.2 out of 10, Wonderful, (5)
"Endroit bien situé pour rayonner aux alentours. chambres propres et en bon état, il manque juste un peu de luminosité! Très grande piscine très agréable. Personnel disponible et sympathique. juste un peu de bruit le samedi soir car les voisins ont mis la musique fort mais apparemment c'était exceptionnel"
France
Frederic
$152 nightly
The price is $167
Dec 25 - Dec 26
Total with taxes and fees
Punta Chame Club and Resort

Parkside Plazuela - Tranquility In Boquete 2 Bedroom Condo

Parkside Plazuela - Tranquility In Boquete 2 Bedroom Condo
3.0 star property
El Tropezón
$221 nightly
The price is $243
Jan 19 - Jan 20, 2026
Total with taxes and fees
Parkside Plazuela - Tranquility In Boquete 2 Bedroom Condo

El Cielo by Villa Alejandro

El Cielo by Villa Alejandro
3.5 star property
Boquete
9.4 out of 10, Exceptional, (91)
"We stayed here for a week while in Boquete and already plan to stay here when we return in a few months. The accomodation was clean with a well-stocked kitchen. The location is perfect to walk around the wonderful shops and restaurants in Boquete. The management team was very responsive to questions, ect. The accomodation is bright and airy and is perfect for short and long-term stays. We cannot recommend El Cielo enough!"
United States
Susan
$117 nightly
The price is $129
Jan 4 - Jan 5, 2026
Total with taxes and fees
El Cielo by Villa Alejandro

Linda Vista Cabins

Linda Vista Cabins
3.0 star property
Alto Boquete
9.2 out of 10, Wonderful, (17)
"Property was the best local accommodation I have had in Panama. The host was outstanding. "
United States
Don
$50 nightly
The price is $55
Jan 3 - Jan 4, 2026
Total with taxes and fees
Linda Vista Cabins

Surfari Bocas

Surfari Bocas
2.5 star property
Bocas del Toro
9.0 out of 10, Wonderful, (53)
"Super friendly and helpful checkin. Clean room, would stay again next time!"
United States
Troy
$40 nightly
The price is $44
Jan 6 - Jan 7, 2026
Total with taxes and fees
Surfari Bocas

zenda house

zenda house
4.0 star property
Hicaco
$89 nightly
The price is $98
Dec 25 - Dec 26
Total with taxes and fees
zenda house
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top Panama Hotel Reviews

Find out more about Panama

Discover your perfect Panama vacation rental with Expedia

How many vacation rentals are available in Panama?


Expedia has plenty of vacation rentals to choose from in and around  Panama, so you’re guaranteed to find the right one for you. 


How much is a vacation rental in Panama?


The selection of Panama vacation rentals we have selected for you start as low as $86 per night. Entering your travel dates in the search wizard you might find even better deals!


What type of vacation rental can I get in Panama?


Vacation rentals in Panama come in all shapes and sizes, and your options depend on your chosen travel dates. You could entertain in a blissful vacation home, chill in a private apartment, or find family fun at a resort. Expedia offers a superb choice of Panama vacation rentals to suit everyone. 


Why should I choose a vacation rental in Panama?


Expedia’s vacation rentals provide cozy comforts you can sink into on your own schedule. You’ll enjoy your own space in a property with a kitchen, a pool, a garden etc. Maybe you’ll prefer somewhere with a spa or kids activities. A Panama vacation rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a vacation rental with multiple bedrooms and shared living spaces to kick back in. 


How do I find the best deal on a vacation rental in Panama?


Find vacation rentals in Panama by viewing Expedia’s latest deals, or enter your travel dates and use the filters to select by amenities, price, or rating. Dive into the reviews to get a true feeling of which is your favorite vacation rental in Panama.  


What amenities are available in a vacation rental in Panama?


The choice is yours! Perhaps you love cooking in a well-equipped kitchen. Or maybe a late breakfast and a swimming pool is more your thing. Of course, there’s always the treat of having your own hot tub. Expedia has a vast range of amenities in Panama vacation rentals designed to suit every budget and trip type.


When is the best time to stay in a vacation rental in Panama?   


Everytime is a great time to head to Panama! Staying in a Panama vacation rentals you will always find lots going on to keep you entertained. 


Why book a vacation rental with Expedia?


Expedia has locked in amazing deals on a huge selection of impressive vacation rentals in Panama. We give you the information and inspiration you need all in one place. With so many properties to choose from, you know you can book your perfect Panama vacation rental with confidence. ANd don’t forget, if you bundle with a flight or a car rental in Panama, you can save even more.


Can I cancel my vacation rental through Expedia?  


Yes, you can cancel or change your Panama vacation rental by contacting your property manager directly. Contact details are easy to find on your itinerary in Trips. For more information, check out our Customer Service Portal and we’ll help you get everything sorted.  


Explore a world of travel with Expedia