Title: Where to Stay in Santa Cruz: Best neighborhoods | Expedia.com

[Hotels in Santa Cruz](https://expedia.com/Santa-Cruz-Hotels.d6053940.Travel-Guide-Hotels)[Vacation Rentals in Santa Cruz](https://expedia.com/Santa-Cruz-Vacation-Rentals.d6053940.Travel-Guide-VacationRentals)[Flights to Santa Cruz](https://expedia.com/Cheap-Flights-To-Santa-Cruz.d6053940.Travel-Guide-Flights)[Things to do in Santa Cruz](https://expedia.com/Things-To-Do-In-Santa-Cruz.d6053940.Travel-Guide-Activities)[Car Rentals in Santa Cruz](https://expedia.com/Car-Rentals-In-Santa-Cruz.d6053940.Car-Rental-Guide)[Santa Cruz Vacation Packages](https://expedia.com/Santa-Cruz.d6053940.Destination-Travel-Guides)

# Where to stay

## in Santa Cruz

## Visit Santa Cruz

Best places to stay for families

Top luxury accommodations in Santa Cruz

Best places to stay with pools

Best places to stay near the airport

[Santa Cruz Travel Guide](https://expedia.com/Santa-Cruz.dx6053940)

## Santa Cruz awaits: its cafes, zoo, cathedral, and more! 

Venture to sights like Plaza 24 de Septiembre and Blacutt Square as you discover Santa Cruz—a city also notable for its shopping.

![San Lorenzo Cathedral showing a garden](https://images.trvl-media.com/place/6098830/62a42b3d-1dbd-4a81-8566-cea655ebca33.jpg)

![Santa Cruz which includes a city](https://images.trvl-media.com/place/6053940/75ffd331-c4fa-4895-94e7-13da747334c7.jpg)

![San Lorenzo Cathedral which includes heritage architecture and heritage elements](https://images.trvl-media.com/place/6098830/0b09144b-3bd2-4292-8648-1903a9368baa.jpg)

![Santa Cruz which includes a city](https://images.trvl-media.com/place/6053940/61fe045e-dc5a-4dde-a0c1-963d4b39646b.jpg)

![San Lorenzo Cathedral](https://images.trvl-media.com/place/6098830/96c7550f-ea15-4520-9904-6b7480545dec.jpg)

![San Lorenzo Cathedral featuring heritage architecture and heritage elements](https://images.trvl-media.com/place/6098830/499c5bd8-4595-4abc-8305-42803fb0ddb1.jpg)

## Best places to stay for families

[Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel](https://www.expedia.com/Santa-Cruz-Hotels-Los-Tajibos-Hotel-And-Convention-Center.h18758.Hotel-Information) is a hotel featuring 2 restaurants and free parking that guests like for its helpful staff. It's located a short 13-minute walk from Santa Cruz Zoo. [Marriott Santa Cruz de la Sierra Hotel](https://www.expedia.com/Santa-Cruz-Hotels-Marriott-Santa-Cruz-De-La-Sierra-Hotel.h21490226.Hotel-Information) is a hotel featuring an outdoor pool and a restaurant that guests like for its helpful staff. You'll be just a short distance from Santa Cruz Zoo, located close by. [Camino Real Hotel](https://www.expedia.com/Santa-Cruz-Hotels-Camino-Real-Hotel.h444475.Hotel-Information) is a hotel featuring a children's pool and a restaurant. Your family will be well placed to visit Santa Cruz Zoo and Centro Cultural Oriental, located close by. 

#### Recommended hotels

## Top luxury accommodations in Santa Cruz

[Marriott Santa Cruz de la Sierra Hotel](https://www.expedia.com/Santa-Cruz-Hotels-Marriott-Santa-Cruz-De-La-Sierra-Hotel.h21490226.Hotel-Information) is luxury a hotel featuring a full-service spa and a rooftop terrace that guests like for its helpful staff. [Camino Real Hotel](https://www.expedia.com/Santa-Cruz-Hotels-Camino-Real-Hotel.h444475.Hotel-Information) is luxury a hotel featuring 2 bars and a full-service spa. It's located a short 4-minute walk from Ventura Mall. [Hampton by Hilton Santa Cruz/Equipetrol, Bolivia](https://www.expedia.com/Santa-Cruz-Hotels-Hampton-By-Hilton-Santa-Cruz.h13179436.Hotel-Information) is luxury a hotel featuring a deli and free grocery shopping service. 

#### Recommended hotels

## Best places to stay with pools

[Yotau All Suites Hotel](https://www.expedia.com/Santa-Cruz-Hotels-Yotau-All-Suites-Hotel.h24417.Hotel-Information) is a hotel featuring 2 outdoor pools and 2 restaurants. It's located a short 14-minute walk from Patio Design LifeStyle Center. [Sun Hotel](https://www.expedia.com/Santa-Cruz-Hotels-Sun-Hotel.h12836211.Hotel-Information) is a hotel featuring a kid's pool and free breakfast. [Buganvillas Hotel Suites & Spa](https://www.expedia.com/Santa-Cruz-Hotels-Buganvillas-Hotel-Suites-Spa.h1156088.Hotel-Information) is a hotel featuring a kid's pool and a fitness center. 

#### Recommended hotels

## Best places to stay near the airport

[Ibis Santa Cruz DE LA Sierra](https://www.expedia.com/Santa-Cruz-Hotels-Ibis-Santa-Cruz-DE-LA-Sierra.h87138613.Hotel-Information) is a hotel featuring an airport shuttle and free WiFi that guests like for its helpful staff. The property is situated 2.2 mi / 3.5 km from Santa Cruz (SRZ-El Trompillo) and 9.2 mi / 14.8 km from Santa Cruz (VVI-Viru Viru Intl.). [Camino Real Hotel](https://www.expedia.com/Santa-Cruz-Hotels-Camino-Real-Hotel.h444475.Hotel-Information) is a hotel featuring an airport shuttle and a full-service spa. The property is situated 3.4 mi / 5.5 km from Santa Cruz (SRZ-El Trompillo) and 8.4 mi / 13.5 km from Santa Cruz (VVI-Viru Viru Intl.). [Hampton by Hilton Santa Cruz/Equipetrol, Bolivia](https://www.expedia.com/Santa-Cruz-Hotels-Hampton-By-Hilton-Santa-Cruz.h13179436.Hotel-Information) is a hotel featuring an airport drop-off service and free breakfast. The property is located 3.1 mi / 5 km from Santa Cruz (SRZ-El Trompillo) and 8.7 mi / 14 km from Santa Cruz (VVI-Viru Viru Intl.). 

#### Recommended hotels

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- [Cheap Hotels in Santa Cruz ](https://www.expedia.com/Destinations-In-Santa-Cruz-Cheap-Hotels.0-0-d6297178-tCheapHotels.Hotel-Filter-Destinations)
- [Beach Hotels in Santa Cruz ](https://www.expedia.com/Destinations-In-Santa-Cruz-Beach-Hotel.0-0-d6297178-tBeachHotel.Hotel-Filter-Destinations)
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- [Honeymoon Resorts & in Santa Cruz ](https://www.expedia.com/Destinations-In-Santa-Cruz-Honeymoon-Hotels.0-0-d6297178-tHoneymoonHotels.Hotel-Filter-Destinations)
- [Hotels near Plaza 24 de Septiembre ](https://www.expedia.com/Plaza-24-De-Septiembre-Hotels.0-l6098828-0.Travel-Guide-Filter-Hotels)
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- [Hotels near Cine Center ](https://www.expedia.com/Cine-Center-Hotels.0-l6126769-0.Travel-Guide-Filter-Hotels)

- [Flights to Santa Cruz ](https://www.expedia.com/Destinations-In-Santa-Cruz.d6297178.Flight-Destinations)
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- [Flights from Toronto (YYZ) to Santa Cruz (SRZ) ](https://www.expedia.com/lp/flights/yyz/srz/toronto-to-santa-cruz)

- [Visit Santa Cruz ](https://www.expedia.com/Santa-Cruz.dx6297178)
- [Sacred Art Museum ](https://www.expedia.com/Sacred-Art-Museum-Santa-Cruz.d553248621563217782.Vacation-Attraction)
- [San Lorenzo Cathedral ](https://www.expedia.com/San-Lorenzo-Cathedral-Santa-Cruz.d6098830.Vacation-Attraction)
- [Franco Aleman Cultural Center ](https://www.expedia.com/Franco-Aleman-Cultural-Center-Santa-Cruz.d553248621532371069.Vacation-Attraction)
- [Santa Cruz Vacations ](https://www.expedia.com/Santa-Cruz.d6297178.Destination-Travel-Guides)
- [Plaza 24 de Septiembre ](https://www.expedia.com/Plaza-24-De-Septiembre-Santa-Cruz.d6098828.Vacation-Attraction)
- [La Recova Artisan Walk ](https://www.expedia.com/La-Recova-Artisan-Walk-Santa-Cruz.d553248621532371683.Vacation-Attraction)
- [Guarani Nandereko Nomai Art and Culture Center ](https://www.expedia.com/Guarani-Nandereko-Nomai-Art-And-Culture-Center-Santa-Cruz.d553248621532371685.Vacation-Attraction)
- [Artecampo ](https://www.expedia.com/Artecampo-Santa-Cruz.d553248621532371681.Vacation-Attraction)
- [Arenal Park ](https://www.expedia.com/Arenal-Park-Santa-Cruz.d553248621563217785.Vacation-Attraction)
- [Ethno-Folkloric Museum ](https://www.expedia.com/Ethno-Folkloric-Museum-Santa-Cruz.d6098834.Vacation-Attraction)
- [Ramon Tahuichi Aguilera Stadium ](https://www.expedia.com/Ramon-Tahuichi-Aguilera-Stadium-Santa-Cruz.d6098832.Vacation-Attraction)
- [Cine Center ](https://www.expedia.com/Cine-Center-Santa-Cruz.d6126769.Vacation-Attraction)

- [Santa Cruz Vacation Rentals ](https://www.expedia.com/Destinations-In-Santa-Cruz.d6297178.Vacation-Rental-Destinations)

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