Title: Top Santa Cruz Hotels: 2026 Best Hotels in Santa Cruz - Expedia.com [Santa Cruz Travel Guide](https://expedia.com/Santa-Cruz.dx6297178)[Vacation Rentals in Santa Cruz](https://expedia.com/Destinations-In-Santa-Cruz.d6297178.Vacation-Rental-Destinations)[Santa Cruz Flights](https://expedia.com/Destinations-In-Santa-Cruz.d6297178.Flight-Destinations)[Car Rentals in Santa Cruz](https://expedia.com/Destinations-In-Santa-Cruz.d6297178.Car-Rental-Destinations)[Santa Cruz Vacations](https://expedia.com/Santa-Cruz.d6297178.Destination-Travel-Guides) ![San Lorenzo Cathedral which includes a church or cathedral, heritage architecture and heritage elements](https://images.trvl-media.com/place/6098830/d6a325c3-d504-4e1a-ab2b-0e430beefd40.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6098830/d6a325c3-d504-4e1a-ab2b-0e430beefd40.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Top Cities in Santa Cruz ![San Lorenzo Cathedral showing a garden](https://images.trvl-media.com/place/6098830/62a42b3d-1dbd-4a81-8566-cea655ebca33.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Santa Cruz [](https://expedia.com/Santa-Cruz-Hotels.d6053940.Travel-Guide-Hotels) ![Mountain view in Samaipata, Florida Province of the Santa Cruz Department, Bolivia](https://images.trvl-media.com/place/6200976/99855abd-1497-49bc-91a5-ef76c4e902cb.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Samaipata [](https://expedia.com/Samaipata-Hotels.d6200976.Travel-Guide-Hotels) ![Portrait of a Tobas warrior during carnival called The Devil Dance (La Diablada), Oruro, Bolivia](https://images.trvl-media.com/place/6352296/feec42f5-cbd9-4576-97cc-129e51391796.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Warnes [](https://expedia.com/Warnes-Hotels.d6352296.Travel-Guide-Hotels) ![Jesuit Mission wall paintings in San Jose de Chiquitos, Bolivia](https://images.trvl-media.com/place/6344854/c34a2d19-1f8b-4361-810e-e1669bf071f5.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### San Jose de Chiquitos [](https://expedia.com/San-Jose-De-Chiquitos-Hotels.d6344854.Travel-Guide-Hotels) ## Check prices for these dates Tonight [Mar 22 - Mar 23](https://www.expedia.com/Hotel-Search?regionId=6297178&startDate=2026-03-22&endDate=2026-03-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 23 - Mar 24](https://www.expedia.com/Hotel-Search?regionId=6297178&startDate=2026-03-23&endDate=2026-03-24&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Mar 27 - Mar 29](https://www.expedia.com/Hotel-Search?regionId=6297178&startDate=2026-03-27&endDate=2026-03-29&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Apr 3 - Apr 5](https://www.expedia.com/Hotel-Search?regionId=6297178&startDate=2026-04-03&endDate=2026-04-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Santa Cruz hotels ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/18800/18758/ce43592e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/20000/18800/18758/e3511d3e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/1000000/20000/18800/18758/7d01dcfa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Banquet hall](https://images.trvl-media.com/lodging/1000000/20000/18800/18758/9bf66d6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel [](https://www.expedia.com/Santa-Cruz-Hotels-Los-Tajibos-Hotel-And-Convention-Center.h18758.Hotel-Information) Santa Cruz 9.0/10 Wonderful (365 reviews) "Lovely staff. Great buffets. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Amanda $136 nightly $136 total Mar 29 - Mar 30 [](https://www.expedia.com/Santa-Cruz-Hotels-Los-Tajibos-Hotel-And-Convention-Center.h18758.Hotel-Information) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/22000000/21500000/21490300/21490226/02f3d22f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/22000000/21500000/21490300/21490226/4f7a4f26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/22000000/21500000/21490300/21490226/00c20228.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; international cuisine ](https://images.trvl-media.com/lodging/22000000/21500000/21490300/21490226/e8e161c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Marriott Santa Cruz de la Sierra Hotel [](https://www.expedia.com/Santa-Cruz-Hotels-Marriott-Santa-Cruz-De-La-Sierra-Hotel.h21490226.Hotel-Information) Santa Cruz 9.0/10 Wonderful (220 reviews) "Great hotel, food and location albeit a little expensive " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Reinaldo $106 nightly $106 total Mar 31 - Apr 1 [](https://www.expedia.com/Santa-Cruz-Hotels-Marriott-Santa-Cruz-De-La-Sierra-Hotel.h21490226.Hotel-Information) ![BBQ/picnic area](https://images.trvl-media.com/lodging/116000000/115110000/115103700/115103642/874f6beb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/116000000/115110000/115103700/115103642/f90ac675.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/116000000/115110000/115103700/115103642/c0388544.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/116000000/115110000/115103700/115103642/d4ffe752.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa Por Temporadas [](https://www.expedia.com/Santa-Cruz-Hotels-Casa-Por-Temporadas.h115103642.Hotel-Information) Santa Cruz 10/10 Exceptional (1 review) "The front desk staff was amazing! We checked in during a rain storm and the hotel had been hit by lightning and their computers and they computers were out. The staff maintained their professionalism and got us in a room quickly. Thank you for your help " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cynthia [](https://www.expedia.com/Santa-Cruz-Hotels-Casa-Por-Temporadas.h115103642.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/450000/444500/444475/9d61826a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/450000/444500/444475/7e3a6616.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, outdoor pool, pool umbrellas](https://images.trvl-media.com/lodging/1000000/450000/444500/444475/e96a8418.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; garden views](https://images.trvl-media.com/lodging/1000000/450000/444500/444475/01205665.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Camino Real Hotel [](https://www.expedia.com/Santa-Cruz-Hotels-Camino-Real-Hotel.h444475.Hotel-Information) Santa Cruz 9.0/10 Wonderful (420 reviews) "Rooms were very clean and service was excellent " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) JESUS $130 nightly $130 total Apr 1 - Apr 2 [](https://www.expedia.com/Santa-Cruz-Hotels-Camino-Real-Hotel.h444475.Hotel-Information) ![Miscellaneous](https://images.trvl-media.com/lodging/88000000/87140000/87138700/87138613/03d4f9ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/88000000/87140000/87138700/87138613/53c67151.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Miscellaneous](https://images.trvl-media.com/lodging/88000000/87140000/87138700/87138613/f871875e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/88000000/87140000/87138700/87138613/ee947f37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ibis Santa Cruz DE LA Sierra [](https://www.expedia.com/Santa-Cruz-Hotels-Ibis-Santa-Cruz-DE-LA-Sierra.h87138613.Hotel-Information) Santa Cruz 9.6/10 Exceptional (96 reviews) "Nice place" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Juan Carlos $55 nightly $55 total Mar 23 - Mar 24 [](https://www.expedia.com/Santa-Cruz-Hotels-Ibis-Santa-Cruz-DE-LA-Sierra.h87138613.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/13000000/12840000/12836300/12836211/c21617f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/13000000/12840000/12836300/12836211/630a5caa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor banquet area](https://images.trvl-media.com/lodging/13000000/12840000/12836300/12836211/fd471fdf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Suite, 2 Queen Beds, Pool View | View from room](https://images.trvl-media.com/lodging/13000000/12840000/12836300/12836211/5c906787.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sun Hotel [](https://www.expedia.com/Santa-Cruz-Hotels-Sun-Hotel.h12836211.Hotel-Information) Santa Cruz 8.2/10 Very Good (353 reviews) "Awesome place " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) John $97 nightly $97 total Mar 27 - Mar 28 [](https://www.expedia.com/Santa-Cruz-Hotels-Sun-Hotel.h12836211.Hotel-Information) ![Outdoor pool, open 9:00 AM to 8:00 PM, sun loungers](https://images.trvl-media.com/lodging/25000000/24410000/24404300/24404225/b86b5103.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Panoramic Apartment, 1 King Bed with Sofa bed, Terrace | Premium bedding, down comforters, Tempur-Pedic beds, in-room safe](https://images.trvl-media.com/lodging/25000000/24410000/24404300/24404225/3e7101b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/25000000/24410000/24404300/24404225/0144c46c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast (USD 2.40 per person)](https://images.trvl-media.com/lodging/25000000/24410000/24404300/24404225/e3b6b11f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Premium Suites Deluxe Aparthotel Equipetrol [](https://www.expedia.com/Santa-Cruz-Hotels-Premium-Suites-Deluxe-Aparthotel-Equipetrol.h24404225.Hotel-Information) Santa Cruz 9.0/10 Wonderful (89 reviews) "Good price, great hotel!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) James $36 nightly $36 total Apr 21 - Apr 22 [](https://www.expedia.com/Santa-Cruz-Hotels-Premium-Suites-Deluxe-Aparthotel-Equipetrol.h24404225.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/70000000/69570000/69566300/69566260/efe5b8af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/70000000/69570000/69566300/69566260/fb4d1503.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/70000000/69570000/69566300/69566260/864143db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/70000000/69570000/69566300/69566260/2f3b612d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Novotel Santa Cruz De La Sierra [](https://www.expedia.com/Santa-Cruz-Hotels-Novotel-Santa-Cruz-De-La-Sierra.h69566260.Hotel-Information) Santa Cruz 9.2/10 Wonderful (109 reviews) "Luxurious hotel,very chic and beautiful." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cristhian $89 nightly $89 total Apr 22 - Apr 23 [](https://www.expedia.com/Santa-Cruz-Hotels-Novotel-Santa-Cruz-De-La-Sierra.h69566260.Hotel-Information) ![1 bedroom, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/6000000/5930000/5928300/5928237/9a481119.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business Apartment, 2 Bedrooms (Plus) | In-room dining](https://images.trvl-media.com/lodging/6000000/5930000/5928300/5928237/db59d5da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/6000000/5930000/5928300/5928237/3d263a1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/6000000/5930000/5928300/5928237/b0eabde8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Apart Hotel Premium Suites Santa Cruz [](https://www.expedia.com/Santa-Cruz-Hotels-Apart-Hotel-Premium-Suites-Santa-Cruz.h5928237.Hotel-Information) Santa Cruz 8.6/10 Excellent (100 reviews) "Place is clean , safe area , walking distance to shops " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nataly [](https://www.expedia.com/Santa-Cruz-Hotels-Apart-Hotel-Premium-Suites-Santa-Cruz.h5928237.Hotel-Information) ![Lounge](https://images.trvl-media.com/lodging/14000000/13180000/13179500/13179436/65fab765.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/14000000/13180000/13179500/13179436/34d33eda.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/14000000/13180000/13179500/13179436/e77454e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/14000000/13180000/13179500/13179436/794bff22.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton by Hilton Santa Cruz/Equipetrol, Bolivia [](https://www.expedia.com/Santa-Cruz-Hotels-Hampton-By-Hilton-Santa-Cruz.h13179436.Hotel-Information) Santa Cruz 9.2/10 Wonderful (265 reviews) "The room was clean, breakfast was standard for South America and the staff were great. However, the bed was advertised as a queen and it was a double bed. The rolling desk chair on the tile floor is a serious accident waiting to happen. I enjoyed the views from the rooftop buffet. " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Patrick $74 nightly $74 total Mar 27 - Mar 28 [](https://www.expedia.com/Santa-Cruz-Hotels-Hampton-By-Hilton-Santa-Cruz.h13179436.Hotel-Information) ![Junior Room, 1 King Bed | Egyptian cotton sheets, premium bedding, pillowtop beds, minibar](https://images.trvl-media.com/lodging/76000000/75260000/75254900/75254801/67f62531.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/76000000/75260000/75254900/75254801/7d4fe05c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/76000000/75260000/75254900/75254801/2463660e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/76000000/75260000/75254900/75254801/6b4d2c57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### HOTEL OSHO [](https://www.expedia.com/Santa-Cruz-Hotels-HOTEL-OSHO.h75254801.Hotel-Information) Santa Cruz 9.4/10 Exceptional (46 reviews) "Room was great and staff were very accommodating!" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) David $56 nightly $56 total Mar 23 - Mar 24 [](https://www.expedia.com/Santa-Cruz-Hotels-HOTEL-OSHO.h75254801.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/83000000/82390000/82389700/82389693/a88a9ace.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop terrace](https://images.trvl-media.com/lodging/83000000/82390000/82389700/82389693/90ebd1b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/83000000/82390000/82389700/82389693/bd6aa283.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/83000000/82390000/82389700/82389693/3169990b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Chairú Eco Hotel [](https://www.expedia.com/Santa-Cruz-Hotels-Chairu-Eco-Hotel.h82389693.Hotel-Information) Santa Cruz 9.4/10 Exceptional (59 reviews) "Staff was very courteous. They went above & beyond. Location was great!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) America [](https://www.expedia.com/Santa-Cruz-Hotels-Chairu-Eco-Hotel.h82389693.Hotel-Information) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/14000000/13460000/13455900/13455822/97b153fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/14000000/13460000/13455900/13455822/6bafe83e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sauna, hot tub, steam room, massages](https://images.trvl-media.com/lodging/14000000/13460000/13455900/13455822/201c3a8c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/14000000/13460000/13455900/13455822/98bdb5e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Cortez [](https://www.expedia.com/Santa-Cruz-Hotels-Hotel-Cortez.h13455822.Hotel-Information) Santa Cruz 9.2/10 Wonderful (131 reviews) "Lovely hotel. Great room, location, staff and amenities. " ![Norway](https://a.travel-assets.com/egds/marks/flags/no.svg) Solvei Emily Brekke $125 nightly $125 total Apr 10 - Apr 11 [](https://www.expedia.com/Santa-Cruz-Hotels-Hotel-Cortez.h13455822.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/118000000/117980000/117976200/117976126/db53d748.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 outdoor pools](https://images.trvl-media.com/lodging/118000000/117980000/117976200/117976126/344828fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Single Room, Balcony, City View | Living area | 45-inch plasma TV with cable channels, Netflix, DVD player](https://images.trvl-media.com/lodging/118000000/117980000/117976200/117976126/43ef311c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Suite | Down comforters, minibar, desk, laptop workspace](https://images.trvl-media.com/lodging/118000000/117980000/117976200/117976126/dd7ea04d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Prince Hotel [](https://www.expedia.com/Santa-Cruz-Hotels-Prince-Hotel.h117976126.Hotel-Information) Santa Cruz 10/10 Exceptional (1 review) "Nice place " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marco $51 nightly $51 total Apr 4 - Apr 5 [](https://www.expedia.com/Santa-Cruz-Hotels-Prince-Hotel.h117976126.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/91000000/90310000/90301900/90301892/436d5514_edited_b786.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/91000000/90310000/90301900/90301892/895a9db7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Minibar, soundproofing, free WiFi, bed sheets](https://images.trvl-media.com/lodging/91000000/90310000/90301900/90301892/09ef3c34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/91000000/90310000/90301900/90301892/20d0c7ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Delfines Collection Hotel By Mercure [](https://www.expedia.com/Santa-Cruz-Hotels-Delfines-Collection-Hotel-By-Mercure.h90301892.Hotel-Information) Santa Cruz 9.0/10 Wonderful (84 reviews) "Rooms are always spotless good breakfasts rooftop pool with decent view " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Peter $46 nightly $46 total Mar 27 - Mar 28 [](https://www.expedia.com/Santa-Cruz-Hotels-Delfines-Collection-Hotel-By-Mercure.h90301892.Hotel-Information) ![Standard Suite, 1 Queen Bed | Hypo-allergenic bedding, down comforters, desk, laptop workspace](https://images.trvl-media.com/lodging/91000000/90600000/90599400/90599395/e2b53d65.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Suite, 1 Queen Bed | Hypo-allergenic bedding, down comforters, desk, laptop workspace](https://images.trvl-media.com/lodging/91000000/90600000/90599400/90599395/9ccfefc5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Suite, 1 Queen Bed | Private kitchen | Mini-fridge, microwave, dishwasher, toaster](https://images.trvl-media.com/lodging/91000000/90600000/90599400/90599395/e1ac9300.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/91000000/90600000/90599400/90599395/3e13fa51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Equipetrol Suites Apart Hotel [](https://www.expedia.com/Santa-Cruz-Hotels-Equipetrol-Suites-Apart-Hotel.h90599395.Hotel-Information) Santa Cruz 8.8/10 Excellent (13 reviews) "Perfect hotel" ![Turkey](https://a.travel-assets.com/egds/marks/flags/tr.svg) Yener $48 nightly $48 total Mar 23 - Mar 24 [](https://www.expedia.com/Santa-Cruz-Hotels-Equipetrol-Suites-Apart-Hotel.h90599395.Hotel-Information) ![Massages](https://images.trvl-media.com/lodging/61000000/60340000/60335700/60335614/6b27e04a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lunch and dinner served](https://images.trvl-media.com/lodging/61000000/60340000/60335700/60335614/1b68b7f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/61000000/60340000/60335700/60335614/9c172db1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/61000000/60340000/60335700/60335614/d2cd08da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Swissôtel Santa Cruz De La Sierra [](https://www.expedia.com/Santa-Cruz-Hotels-Swissotel-Santa-Cruz-De-La-Sierra.h60335614.Hotel-Information) Santa Cruz 9.2/10 Wonderful (87 reviews) "Beautiful hotel" ![Australia](https://a.travel-assets.com/egds/marks/flags/au.svg) Joanna $148 nightly $148 total Apr 6 - Apr 7 [](https://www.expedia.com/Santa-Cruz-Hotels-Swissotel-Santa-Cruz-De-La-Sierra.h60335614.Hotel-Information) ![Daily buffet breakfast (USD 10 per person)](https://images.trvl-media.com/lodging/11000000/10210000/10209600/10209582/d4a4ff03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 Queen Bed | Minibar, in-room safe, desk, blackout drapes](https://images.trvl-media.com/lodging/11000000/10210000/10209600/10209582/927d4cc1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/11000000/10210000/10209600/10209582/84ac5773.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/11000000/10210000/10209600/10209582/bda280c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel LP Equipetrol [](https://www.expedia.com/Santa-Cruz-Hotels-Hotel-LP-Equipetrol.h10209582.Hotel-Information) Santa Cruz 8.2/10 Very Good (204 reviews) "Nice place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ricardo [](https://www.expedia.com/Santa-Cruz-Hotels-Hotel-LP-Equipetrol.h10209582.Hotel-Information) ![Triple Room | Free WiFi](https://images.trvl-media.com/lodging/113000000/113000000/112993700/112993678/8e2f8b6e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/113000000/113000000/112993700/112993678/1b035e5d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/113000000/113000000/112993700/112993678/cc4cd467.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/113000000/113000000/112993700/112993678/w1179h740x0y0-89df5329.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Las Américas [](https://www.expedia.com/Santa-Cruz-Hotels-Hotel-Las-Americas.h112993678.Hotel-Information) Santa Cruz 8.0/10 Very Good (2 reviews) "O chuveiro foi impossível tomar um.banho de qualidade " ![Brazil](https://a.travel-assets.com/egds/marks/flags/br.svg) Jean $34 nightly $34 total Mar 23 - Mar 24 [](https://www.expedia.com/Santa-Cruz-Hotels-Hotel-Las-Americas.h112993678.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/11000000/10210000/10202800/10202755/406a6473.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/11000000/10210000/10202800/10202755/a7124411.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/11000000/10210000/10202800/10202755/bdf964e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Staircase](https://images.trvl-media.com/lodging/11000000/10210000/10202800/10202755/c3eb7cf0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Alfonsina Hotel Boutique by Inboccaluppo [](https://www.expedia.com/Santa-Cruz-Hotels-Inboccalupo-The-Hotel-Boutique.h10202755.Hotel-Information) Santa Cruz 9.4/10 Exceptional (43 reviews) "Beautiful place, wonderful artwork" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Elizabeth $107 nightly $107 total Mar 23 - Mar 24 [](https://www.expedia.com/Santa-Cruz-Hotels-Inboccalupo-The-Hotel-Boutique.h10202755.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-04-05&endDate=2026-04-06®ionId=6297178&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Great weekend hotel deals in Santa Cruz ### Showing deals for:**Apr 3 - Apr 5** ### Image gallery for Casa Por Temporadas ![BBQ/picnic area](https://images.trvl-media.com/lodging/116000000/115110000/115103700/115103642/874f6beb.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Casa Por Temporadas Santa Cruz **10/10**Exceptional (1 review) Member Price available $83 nightly $167 total [Sign in for Member Price ](https://www.expedia.com/user/signin?uurl=e3id%3Dredr%26rurl%3D%2FHotel-Search%3FstartDate%3D2026-04-03%26endDate%3D2026-04-05%26selected%3D115103642%26adults%3D2) [](https://www.expedia.com/Hotel-Search?startDate=2026-04-03&endDate=2026-04-05&selected=115103642&adults=2) ### Image gallery for Terranova Suites ![Bar (on property)](https://images.trvl-media.com/lodging/11000000/10960000/10950300/10950250/7e27a563.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Terranova Suites Santa Cruz **8.0/10**Very Good (90 reviews) 10% off $52 nightly $104 total [](https://www.expedia.com/Hotel-Search?startDate=2026-04-03&endDate=2026-04-05&selected=10950250&adults=2) ### Image gallery for Novotel Santa Cruz De La Sierra ![Lobby sitting area](https://images.trvl-media.com/lodging/70000000/69570000/69566300/69566260/efe5b8af.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) VIP Access ### Novotel Santa Cruz De La Sierra Santa Cruz **9.2/10**Wonderful (109 reviews) Member Price available $145 nightly $291 total [Sign in for Member Price ](https://www.expedia.com/user/signin?uurl=e3id%3Dredr%26rurl%3D%2FHotel-Search%3FstartDate%3D2026-04-03%26endDate%3D2026-04-05%26selected%3D69566260%26adults%3D2) [](https://www.expedia.com/Hotel-Search?startDate=2026-04-03&endDate=2026-04-05&selected=69566260&adults=2) ### Image gallery for Casa Vida ![House | Pool | Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/16000000/15040000/15030900/15030862/cb1eeefb.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Casa Vida Santa Cruz **9.0/10**Wonderful (2 reviews) 10% off $95 nightly $189 total [](https://www.expedia.com/Hotel-Search?startDate=2026-04-03&endDate=2026-04-05&selected=15030862&adults=2) ### Image gallery for Hotel BY Armonia SCZ ![Dining room](https://images.trvl-media.com/lodging/23000000/22220000/22210900/22210823/3197cbe9.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Hotel BY Armonia SCZ Santa Cruz **8.4/10**Very Good (7 reviews) 18% off $77 nightly $155 total [](https://www.expedia.com/Hotel-Search?startDate=2026-04-03&endDate=2026-04-05&selected=22210823&adults=2) ### Image gallery for Hotel LP Santa Cruz Centro ![Standard Room, 2 Twin Beds | Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/3000000/2770000/2761500/2761435/60285ad5.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) VIP Access ### Hotel LP Santa Cruz Centro Santa Cruz **8.0/10**Very Good (284 reviews) 34% off $49 nightly $104 total [](https://www.expedia.com/Hotel-Search?startDate=2026-04-03&endDate=2026-04-05&selected=2761435&adults=2) ### Image gallery for Equipetrol Suites Apart Hotel ![Standard Suite, 1 Queen Bed | Hypo-allergenic bedding, down comforters, desk, laptop workspace](https://images.trvl-media.com/lodging/91000000/90600000/90599400/90599395/e2b53d65.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) VIP Access ### Equipetrol Suites Apart Hotel Santa Cruz **8.8/10**Excellent (13 reviews) 22% off $48 nightly $97 total [](https://www.expedia.com/Hotel-Search?startDate=2026-04-03&endDate=2026-04-05&selected=90599395&adults=2) ### Image gallery for Hotel Las Américas ![Triple Room | Free WiFi](https://images.trvl-media.com/lodging/113000000/113000000/112993700/112993678/8e2f8b6e.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Hotel Las Américas Santa Cruz **8.0/10**Very Good (2 reviews) 10% off $35 nightly $69 total [](https://www.expedia.com/Hotel-Search?startDate=2026-04-03&endDate=2026-04-05&selected=112993678&adults=2) ### Image gallery for Dpt TV 58" / Swimming pool / Cowork / Gym / Queen Bed ![Outdoor pool](https://images.trvl-media.com/lodging/115000000/114480000/114470600/114470519/6e34acbd.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Dpt TV 58" / Swimming pool / Cowork / Gym / Queen Bed Santa Cruz **10/10**Exceptional (1 review) 7% off $29 nightly $84 total [](https://www.expedia.com/Hotel-Search?startDate=2026-04-03&endDate=2026-04-05&selected=114470519&adults=2) ### Image gallery for Hotel Continental Park ![View from property](https://images.trvl-media.com/lodging/16000000/15250000/15240400/15240320/973a651d.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Hotel Continental Park Santa Cruz **8.8/10**Excellent (25 reviews) 14% off $65 nightly $131 total [](https://www.expedia.com/Hotel-Search?startDate=2026-04-03&endDate=2026-04-05&selected=15240320&adults=2) ### Image gallery for Camino Real Hotel ![Reception](https://images.trvl-media.com/lodging/1000000/450000/444500/444475/9d61826a.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) VIP Access ### Camino Real Hotel Santa Cruz **9.0/10**Wonderful (420 reviews) Member Price available $285 nightly $570 total [Sign in for Member Price ](https://www.expedia.com/user/signin?uurl=e3id%3Dredr%26rurl%3D%2FHotel-Search%3FstartDate%3D2026-04-03%26endDate%3D2026-04-05%26selected%3D444475%26adults%3D2) [](https://www.expedia.com/Hotel-Search?startDate=2026-04-03&endDate=2026-04-05&selected=444475&adults=2) ### Image gallery for Alfonsina Hotel Boutique by Inboccaluppo ![Front of property](https://images.trvl-media.com/lodging/11000000/10210000/10202800/10202755/406a6473.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Alfonsina Hotel Boutique by Inboccaluppo Santa Cruz **9.4/10**Exceptional (43 reviews) 10% off $134 nightly $268 total [](https://www.expedia.com/Hotel-Search?startDate=2026-04-03&endDate=2026-04-05&selected=10202755&adults=2) ### Image gallery for Apart Hotel Toborochi ![Front of property](https://images.trvl-media.com/lodging/11000000/10040000/10032000/10031984/83c0e879.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Apart Hotel Toborochi Santa Cruz **8.8/10**Excellent (60 reviews) 14% off $77 nightly $154 total [](https://www.expedia.com/Hotel-Search?startDate=2026-04-03&endDate=2026-04-05&selected=10031984&adults=2) ### Image gallery for Hotel Cortez ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/14000000/13460000/13455900/13455822/97b153fa.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Hotel Cortez Santa Cruz **9.2/10**Wonderful (131 reviews) 11% off $136 nightly $273 total [](https://www.expedia.com/Hotel-Search?startDate=2026-04-03&endDate=2026-04-05&selected=13455822&adults=2) ### Image gallery for TRYP by Wyndham Santa Cruz ![Exterior detail](https://images.trvl-media.com/lodging/46000000/45620000/45617400/45617372/efaab5ae.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### TRYP by Wyndham Santa Cruz Santa Cruz **9.2/10**Wonderful (155 reviews) 15% off $84 nightly $168 total [](https://www.expedia.com/Hotel-Search?startDate=2026-04-03&endDate=2026-04-05&selected=45617372&adults=2) ### Image gallery for Hotel LP Equipetrol ![Daily buffet breakfast (USD 10 per person)](https://images.trvl-media.com/lodging/11000000/10210000/10209600/10209582/d4a4ff03.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) VIP Access ### Hotel LP Equipetrol Santa Cruz **8.2/10**Very Good (204 reviews) 34% off $45 nightly $94 total [](https://www.expedia.com/Hotel-Search?startDate=2026-04-03&endDate=2026-04-05&selected=10209582&adults=2) ### Image gallery for Chairú Eco Hotel ![Front of property](https://images.trvl-media.com/lodging/83000000/82390000/82389700/82389693/a88a9ace.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Chairú Eco Hotel Santa Cruz **9.4/10**Exceptional (59 reviews) 25% off $56 nightly $113 total [](https://www.expedia.com/Hotel-Search?startDate=2026-04-03&endDate=2026-04-05&selected=82389693&adults=2) ### Image gallery for Esmeralda Vista Hideaway ![Pool](https://images.trvl-media.com/lodging/116000000/115990000/115984600/115984525/b254f3fd.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Esmeralda Vista Hideaway Santa Cruz **10/10**Exceptional (1 review) 7% off $51 nightly $143 total [](https://www.expedia.com/Hotel-Search?startDate=2026-04-03&endDate=2026-04-05&selected=115984525&adults=2) ### Image gallery for Sun Hotel ![Outdoor pool](https://images.trvl-media.com/lodging/13000000/12840000/12836300/12836211/c21617f6.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) VIP Access ### Sun Hotel Santa Cruz **8.2/10**Very Good (353 reviews) 19% off $97 nightly $194 total [](https://www.expedia.com/Hotel-Search?startDate=2026-04-03&endDate=2026-04-05&selected=12836211&adults=2) ### Image gallery for Apart Hotel Premium Suites Santa Cruz ![1 bedroom, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/6000000/5930000/5928300/5928237/9a481119.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Apart Hotel Premium Suites Santa Cruz Santa Cruz **8.6/10**Excellent (100 reviews) 10% off $27 nightly $54 total [](https://www.expedia.com/Hotel-Search?startDate=2026-04-03&endDate=2026-04-05&selected=5928237&adults=2) ### Image gallery for Ibis Santa Cruz DE LA Sierra ![Miscellaneous](https://images.trvl-media.com/lodging/88000000/87140000/87138700/87138613/03d4f9ed.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Ibis Santa Cruz DE LA Sierra Santa Cruz **9.6/10**Exceptional (96 reviews) Member Price available $55 nightly $110 total [Sign in for Member Price ](https://www.expedia.com/user/signin?uurl=e3id%3Dredr%26rurl%3D%2FHotel-Search%3FstartDate%3D2026-04-03%26endDate%3D2026-04-05%26selected%3D87138613%26adults%3D2) [](https://www.expedia.com/Hotel-Search?startDate=2026-04-03&endDate=2026-04-05&selected=87138613&adults=2) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Santa-Cruz.d6297178.Hotel-Destinations)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Santa-Cruz.d6297178.Hotel-Destinations) ## Top Santa Cruz Hotel Reviews ![Sun Hotel](https://images.trvl-media.com/lodging/13000000/12840000/12836300/12836211/c21617f6_y.jpg) ### Sun Hotel 10/10 Excellent "Very close to the airport Room is so quiet and comfortable " [](https://expedia.com/Santa-Cruz-Hotels-Sun-Hotel.h12836211.Hotel-Information) ![Hampton by Hilton Santa Cruz/Equipetrol, Bolivia](https://images.trvl-media.com/lodging/14000000/13180000/13179500/13179436/65fab765_y.jpg) ### Hampton by Hilton Santa Cruz/Equipetrol, Bolivia 10/10 Excellent "Super Clean Hotel. The Bathroom looks like a Sauna with a Central Súper Shower. The Bed has a Cloud feeling. Delicious Súper Breakfast. Highly recommended!" [](https://expedia.com/Santa-Cruz-Hotels-Hampton-By-Hilton-Santa-Cruz.h13179436.Hotel-Information) ![Ibis Santa Cruz DE LA Sierra](https://images.trvl-media.com/lodging/88000000/87140000/87138700/87138613/03d4f9ed_y.jpg) ### Ibis Santa Cruz DE LA Sierra 10/10 Excellent "Good " [](https://expedia.com/Santa-Cruz-Hotels-Ibis-Santa-Cruz-DE-LA-Sierra.h87138613.Hotel-Information) ![Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel](https://images.trvl-media.com/lodging/1000000/20000/18800/18758/ce43592e_y.jpg) ### Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel 10/10 Excellent "Yes" [](https://expedia.com/Santa-Cruz-Hotels-Los-Tajibos-Hotel-And-Convention-Center.h18758.Hotel-Information) ![Novotel Santa Cruz De La Sierra](https://images.trvl-media.com/lodging/70000000/69570000/69566300/69566260/efe5b8af_y.jpg) ### Novotel Santa Cruz De La Sierra 10/10 Excellent "Quarto, restaurant, equipe" [](https://expedia.com/Santa-Cruz-Hotels-Novotel-Santa-Cruz-De-La-Sierra.h69566260.Hotel-Information) ![Swissôtel Santa Cruz De La Sierra](https://images.trvl-media.com/lodging/61000000/60340000/60335700/60335614/6b27e04a_y.jpg) ### Swissôtel Santa Cruz De La Sierra 10/10 Excellent "Great room, spacious, quiet and the shower was great" [](https://expedia.com/Santa-Cruz-Hotels-Swissotel-Santa-Cruz-De-La-Sierra.h60335614.Hotel-Information) ![Marriott Santa Cruz de la Sierra Hotel](https://images.trvl-media.com/lodging/22000000/21500000/21490300/21490226/02f3d22f_y.jpg) ### Marriott Santa Cruz de la Sierra Hotel 6/10 Okay "Mattress was hard, pillows flattened, no microwave and fridge was not cooling. Other than that, the personnel were 5 stars, friendly attentive and respectful. " [](https://expedia.com/Santa-Cruz-Hotels-Marriott-Santa-Cruz-De-La-Sierra-Hotel.h21490226.Hotel-Information) ![Chairú Eco Hotel](https://images.trvl-media.com/lodging/83000000/82390000/82389700/82389693/a88a9ace_y.jpg) ### Chairú Eco Hotel 10/10 Excellent "I had room 29, a double bed with balcony. It was beautiful, modern, clean, and in a quiet area but only a couple blocks to restaurants. The breakfast is modest but satisfactory. To the hotel, I would suggest putting electric kettles in each room. I, as well as others, would use this to boil water and not have to rely on bottled water. Just a thought for an "eco" hotel." [](https://expedia.com/Santa-Cruz-Hotels-Chairu-Eco-Hotel.h82389693.Hotel-Information) ![Prince Hotel](https://images.trvl-media.com/lodging/118000000/117980000/117976200/117976126/db53d748_y.jpg) ### Prince Hotel 10/10 Excellent "Nice place " [](https://expedia.com/Santa-Cruz-Hotels-Prince-Hotel.h117976126.Hotel-Information) ## Price trends for hotels in Santa Cruz | Less expensive | More expensive | Next month | | -------------- | -------------- | ---------- | | February | October | $74 | | Month | Price | | --------- | ----- | | January | $74 | | February | $72 | | March | $75 | | April | $74 | | May | $75 | | June | $75 | | July | $75 | | August | $74 | | September | $77 | | October | $80 | | November | $75 | | December | $78 | Price trend information excludes taxes and fees and is based on base rates for a nightly stay for 2 adults found in the last 7 days on our site and averaged for commonly viewed hotels in Santa Cruz. Select dates and complete search for nightly totals inclusive of taxes and fees. ## Guide to exploring around Santa Cruz ### Top reasons to visit Santa Cruz - **Cultural Exploration:** Santa Cruz boasts a rich cultural scene with various attractions, including cathedrals and notable landmarks. - **Urban Adventures:** The city is perfect for urban exploration, featuring stylish neighborhoods and bustling shopping centers. - **Outdoor Activities:** Visitors can enjoy nearby national parks and excursions, ideal for adventure seekers. - **Family-Friendly Options:** Santa Cruz offers a range of activities suitable for families, ensuring everyone has fun. - **Diverse Accommodations:** From budget hostels to comfortable hotels, there's lodging to fit every traveler's needs. ### Find great hotels in Santa Cruz Explore a variety of hotel accommodations in Santa Cruz, Bolivia, ranging from comfortable hotels to budget-friendly hostels. Whether you're traveling for business, looking for family-friendly options, or seeking pet-friendly experiences, Santa Cruz offers a diverse selection of lodging to suit your needs. Discover the best hotels in the area and enjoy a memorable stay in this vibrant city. - **[Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel: ](https://www.expedia.com/Santa-Cruz-Hotels-Los-Tajibos-Hotel-And-Convention-Center.h18758.Hotel-Information)** Los Tajibos is a distinguished 3.5-star hotel that boasts a guest rating of 9.0, offering a unique blend of family-friendly hospitality and modern business amenities. Situated in the heart of Santa Cruz, this hotel is perfect for both leisure and corporate travelers. Families will appreciate the thoughtful amenities, including a First Aid Kit for peace of mind. The lush surroundings and elegant design create a serene atmosphere, making it a perfect retreat after a day of exploring the vibrant city. - **[Marriott Santa Cruz de la Sierra Hotel: ](https://www.expedia.com/Santa-Cruz-Hotels-Marriott-Santa-Cruz-De-La-Sierra-Hotel.h21490226.Hotel-Information)** A luxurious 5-star establishment, the Marriott Santa Cruz de la Sierra Hotel has earned a guest rating of 9.0, showcasing its commitment to excellence. This hotel is ideal for those seeking a lavish vacation experience, with a focus on family and business needs. With amenities like complimentary cribs for little ones, it ensures that families feel right at home. Its upscale facilities, including an inviting pool and exquisite dining options, make it a top choice for travelers looking to indulge in comfort and style. - **[Hampton by Hilton Santa Cruz/Equipetrol, Bolivia: ](https://www.expedia.com/Santa-Cruz-Hotels-Hampton-By-Hilton-Santa-Cruz.h13179436.Hotel-Information)** This 4.5-star hotel shines with a guest rating of 9.2, making it a favored option for families desiring a luxurious stay. Located in the Equipetrol area of Santa Cruz, it offers a range of family amenities, including onsite babysitting services and free cribs. Guests revel in modern, spacious rooms designed for relaxation, alongside a welcoming atmosphere and superior service. Whether you're visiting for leisure or business, this hotel provides a perfect blend of comfort and convenience. ### Where to stay in Santa Cruz Santa Cruz, Bolivia, offers a vibrant mix of culture and urban charm, making it a perfect destination for your vacation. Explore stylish neighborhoods with captivating city views, enjoy sunny weather, and embark on exciting excursions. Discover the tropical vibes and budget-friendly options that cater to families and solo travelers alike. Whether you’re seeking a secluded retreat or a dynamic city experience, Santa Cruz promises an unforgettable getaway filled with rich culture and stunning scenery. - **[Santa Cruz: ](https://www.expedia.com/Santa-Cruz-Hotels.d6053940.Travel-Guide-Hotels)** As the largest city in Bolivia, Santa Cruz is a vibrant hub of culture and commerce. Nestled in the eastern part of the country, it offers a unique blend of modern amenities and traditional charm. Travelers flock to Santa Cruz year-round, especially during peak months like January, July, and September. Here, you can indulge in shopping at bustling malls, explore the beautiful botanical gardens, and visit iconic landmarks such as the picturesque piazza square and the stunning cathedral. The city's diverse culinary scene and lively atmosphere make it an ideal destination for families and culture enthusiasts alike. - **[Samaipata: ](https://www.expedia.com/Samaipata-Hotels.d6200976.Travel-Guide-Hotels)** Located a short drive from Santa Cruz, Samaipata is an enchanting city that beckons outdoor lovers and adventure seekers. With its stunning landscapes and rich history, visitors are drawn to its hiking trails and archaeological sites. Unlike Santa Cruz, Samaipata sees peak visitor numbers in January, July, and September, making it an excellent spot for nature enthusiasts looking for a serene getaway. Highlights include the nearby historic site and breathtaking scenery that allows for immersive experiences in Bolivian nature. The charming town center features local shops and cafes, perfect for unwinding after a day of exploration. - **[Warnes: ](https://www.expedia.com/Warnes-Hotels.d6352296.Travel-Guide-Hotels)** Just north of Santa Cruz, Warnes is a family-friendly city known for its welcoming atmosphere and outdoor activities. The city sees a surge in visitors during September and the holiday season in December and January. Families can enjoy various resorts and shopping centers, making it an ideal destination for those looking to relax and spend quality time together. Nearby attractions include beautiful botanical gardens and the lively piazza square, where you can soak in the local culture. Warnes combines the vibrancy of city life with the tranquility of nature, ensuring a memorable experience for all visitors. ### Things to do in Santa Cruz Santa Cruz, Bolivia, is a vibrant destination perfect for culture enthusiasts and families alike. Visitors can explore bustling shopping centers and malls, offering a fantastic shopping experience. Additionally, the city features resorts that provide relaxation and leisure options. With its rich culture and diverse activities, Santa Cruz promises an exciting urban adventure for every traveler. **Shopping** In Santa Cruz, visit the Ventura Mall for a variety of international brands and local boutiques. For a more authentic experience, check out the Mercado Nuevo, where you can find handmade crafts and unique souvenirs that reflect the Bolivian culture. **Recreation** Experience rejuvenation at the Los Tajibos Hotel Spa, where you can enjoy soothing massages and holistic treatments. For outdoor relaxation, visit Parque Urbano, featuring walking trails and tranquil spaces to unwind amidst nature's beauty. **Adventure** Explore the stunning Amboró National Park, where you can hike through lush forests, spot diverse wildlife, and enjoy breathtaking views. For a thrilling experience, try zip-lining over the canopy or go mountain biking on rugged trails, perfect for adrenaline seekers looking for excitement in nature. **Nightlife** Experience the vibrant nightlife at Casa de la Cerveza on Av. San Martín, where you can enjoy local brews and delicious tapas. For dancing, head to Club Cielo, known for its lively atmosphere and top DJs spinning all night long. \*Distances are measured in a straight line; actual driving distances may vary depending on the route. ### Booking tips and Expedia advantages for Santa Cruz - **The most and least expensive months on average to stay in a hotel:** The cheapest months to stay in Santa Cruz are June to August, where the prices are slightly lower. This is in comparison to April, September and December, where prices are slightly higher. - **The most and least expensive days on average to stay in a hotel:** The least expensive day to stay in Santa Cruz is Saturday. The most expensive day to stay in Santa Cruz is Tuesday. - **Find cheap hotels on Expedia:** Utilize Expedia’s search tool to customize your preferences, such as your budget, desired location, and preferred hotel type. To find the best prices and deals, simply arrange the price filter from lowest to highest. - **Consider bundling your trip:** You can save money by combining your Santa Cruz hotel reservation with your flights and activities through an Expedia package deal. ### Find the best attractions in Santa Cruz Santa Cruz, Bolivia, offers a delightful blend of culture, family-friendly activities, and urban exploration. Visitors can enjoy a range of attractions, including national parks, cathedrals, and notable landmarks. Whether you seek cultural immersion, outdoor adventures, or unique experiences, Santa Cruz has something for every traveler, making it an ideal destination for your vacation. - **[Plaza 24 de Septiembre: ](https://www.expedia.com/Plaza-24-De-Septiembre-Hotels.0-l6098828-0.Travel-Guide-Filter-Hotels)** Experience the vibrant heart of Santa Cruz at Plaza 24 de Septiembre, where you can immerse yourself in local culture among bustling markets, cafes, and beautiful colonial architecture. This lively square is perfect for people-watching and enjoying the city's vibrant atmosphere. - **[Amboró National Park: ](https://www.expedia.com/Amboro-National-Park-Hotels.0-l6098839-0.Travel-Guide-Filter-Hotels)** For nature lovers and adventure seekers, Amboró National Park offers breathtaking scenery and diverse wildlife. Explore its lush trails, stunning waterfalls, and panoramic views for an unforgettable outdoor experience. - **[Blacutt Square: ](https://www.expedia.com/Blacutt-Square-Hotels.0-l6126767-0.Travel-Guide-Filter-Hotels)** Discover Blacutt Square, a unique landmark that serves as a hub for excursions. It's an ideal starting point for guided tours, showcasing the natural beauty and rich culture of the region. ### Best time to go to Santa Cruz The best time to visit Santa Cruz is dependent on what kind of holiday you are seeking. October is its hottest month on average. At this time, visitor numbers are average and weather is mostly sunny with light rain. June is its coolest month on average. At this time, visitor numbers are average and weather is mostly sunny with light rain. | **![calendar](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/calendar.png)Calendar Month** | **![temperature](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__hot.png)Temperature** | **![rain](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__rain.png)Precipitation** | **![mostly](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/21/weather__day_mostly_cloudy.png)Cloudiness** | **![occupation](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/peoplebex.png)Occupancy** | **![price](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/currency_dollar.png)Pricing** | | ---------------------------------------------------------------------------------------------------------------- | -------------------------------------------------------------------------------------------------------------------- | ---------------------------------------------------------------------------------------------------------------- | ---------------------------------------------------------------------------------------------------------------------------- | -------------------------------------------------------------------------------------------------------------- | ------------------------------------------------------------------------------------------------------------- | | January | 78.3°F (25.7°C) | Light Rain | Mostly Sunny | Slightly Low | Average | | February | 77.0°F (25.0°C) | Light Rain | Mostly Cloudy | Slightly High | Average | | March | 76.5°F (24.7°C) | Light Rain | Mostly Sunny | Average | Average | | April | 74.5°F (23.6°C) | Light Rain | Mostly Sunny | Average | Slightly High | | May | 70.2°F (21.2°C) | Light Rain | Mostly Sunny | Slightly Low | Average | | June | 67.8°F (19.9°C) | Light Rain | Mostly Sunny | Average | Slightly Low | | July | 68.5°F (20.3°C) | No Rain | Mostly Sunny | Average | Slightly Low | | August | 72.9°F (22.7°C) | No Rain | Sunny | Slightly High | Slightly Low | | September | 77.9°F (25.5°C) | Light Rain | Sunny | Slightly High | Slightly High | | October | 79.5°F (26.4°C) | Light Rain | Mostly Sunny | Average | Average | | November | 79.3°F (26.3°C) | Light Rain | Mostly Sunny | Average | Average | | December | 78.4°F (25.8°C) | Light Rain | Mostly Sunny | Slightly Low | Slightly High | ### The nearest major airports for your trip to Santa Cruz Traveling to Santa Cruz, Bolivia, is convenient with its primary airport, Viru Viru International Airport ([VVI](https://www.expedia.com/Viru-Viru-Intl-Airport-Hotels.0-aVVI-0.Travel-Guide-Filter-Hotels)), situated 10 miles from the city. Notable nearby hotels include the luxurious Marriott Santa Cruz de la Sierra and [Radisson Hotel Santa Cruz](https://www.expedia.com/Santa-Cruz-Hotels-Radisson-Hotel-Santa-Cruz.h16447274.Hotel-Information), both approximately 9 miles from the airport, along with the [Novotel Santa Cruz De La Sierra](https://www.expedia.com/Santa-Cruz-Hotels-Novotel-Santa-Cruz-De-La-Sierra.h69566260.Hotel-Information), located 11 miles away. For alternative options, Alcantarí International Airport ([SRE](https://www.expedia.com/Alcantari-Intl-Airport-Airport-Hotels.0-aSRE-0.Travel-Guide-Filter-Hotels)) is 164 miles and Chimore Airport (CCA) is 142 miles from Santa Cruz. These hotels offer accessible transportation services to ensure a smooth journey to and from the airport. ## Explore a world of travel with Expedia - Explore a world of travel with Expedia ### Top cities in Santa Cruz - [Santa Cruz Hotels ](https://expedia.com/Santa-Cruz-Hotels.d6053940.Travel-Guide-Hotels) - [Samaipata Hotels ](https://expedia.com/Samaipata-Hotels.d6200976.Travel-Guide-Hotels) - [Warnes Hotels ](https://expedia.com/Warnes-Hotels.d6352296.Travel-Guide-Hotels) - [San Jose de Chiquitos Hotels ](https://expedia.com/San-Jose-De-Chiquitos-Hotels.d6344854.Travel-Guide-Hotels) - [Cuevas Hotels ](https://expedia.com/Cuevas-Hotels.d6350209.Travel-Guide-Hotels) - [Camiri Hotels ](https://expedia.com/Camiri-Hotels.d770.Travel-Guide-Hotels) - [La Higuera Hotels ](https://expedia.com/La-Higuera-Hotels.d830373381713960960.Travel-Guide-Hotels) - [El Torno Hotels ](https://expedia.com/El-Torno-Hotels.d3000419675.Travel-Guide-Hotels) - [Buena Vista Hotels ](https://expedia.com/Buena-Vista-Hotels.d3000445595.Travel-Guide-Hotels) - [Vallegrande Hotels ](https://expedia.com/Vallegrande-Hotels.d6350207.Travel-Guide-Hotels) ### Hotels near popular Attractions - [Hotels near Plaza 24 de Septiembre ](https://expedia.com/Plaza-24-De-Septiembre-Hotels.0-l6098828-0.Travel-Guide-Filter-Hotels) - [Hotels near Ventura Mall ](https://expedia.com/Ventura-Mall-Hotels.0-l553248634697753452-0.Travel-Guide-Filter-Hotels) - [Hotels near Guembe Biocenter ](https://expedia.com/Guembe-Biocenter-Hotels.0-l553248621532465358-0.Travel-Guide-Filter-Hotels) - [Hotels near Ramon Tahuichi Aguilera Stadium ](https://expedia.com/Ramon-Tahuichi-Aguilera-Stadium-Hotels.0-l6098832-0.Travel-Guide-Filter-Hotels) - [Hotels near Amboró National Park ](https://expedia.com/Amboro-National-Park-Hotels.0-l6098839-0.Travel-Guide-Filter-Hotels) - [Hotels near Santa Cruz Zoo ](https://expedia.com/Santa-Cruz-Zoo-Hotels.0-l6098836-0.Travel-Guide-Filter-Hotels) - [Hotels near Lomas de Arena Regional Park ](https://expedia.com/Lomas-De-Arena-Regional-Park-Hotels.0-l553248621563217780-0.Travel-Guide-Filter-Hotels) - [Hotels near Cine Center ](https://expedia.com/Cine-Center-Hotels.0-l6126769-0.Travel-Guide-Filter-Hotels) - [Hotels near Warnes Plaza ](https://expedia.com/Warnes-Plaza-Hotels.0-l553248621594280428-0.Travel-Guide-Filter-Hotels) - [Hotels near Noel Kempff Mercado National Park ](https://expedia.com/Noel-Kempff-Mercado-National-Park-Hotels.0-l6098841-0.Travel-Guide-Filter-Hotels) ### Hotel Theme - [Hotels with Free Breakfast in Santa Cruz ](https://expedia.com/Destinations-In-Santa-Cruz-Hotels-With-Complimentary-Breakfast.0-0-d6297178-tHotelswithComplimentaryBreakfast.Hotel-Filter-Destinations) - [Hotels with a Pool in Santa Cruz ](https://expedia.com/Destinations-In-Santa-Cruz-Hotel-With-Pool.0-0-d6297178-tHotelwithPool.Hotel-Filter-Destinations) - [Business Hotels in Santa Cruz ](https://expedia.com/Destinations-In-Santa-Cruz-Business-Hotel.0-0-d6297178-tBusinessHotel.Hotel-Filter-Destinations) - [Family Hotels in Santa Cruz ](https://expedia.com/Destinations-In-Santa-Cruz-Family-Hotel.0-0-d6297178-tFamilyHotel.Hotel-Filter-Destinations) - [Hotel with a Concierge in Santa Cruz ](https://expedia.com/Destinations-In-Santa-Cruz-Hotel-With-A-Concierge.0-0-d6297178-tHotelwithaConcierge.Hotel-Filter-Destinations) - [Hotels with a Gym in Santa Cruz ](https://expedia.com/Destinations-In-Santa-Cruz-Hotels-With-Fitness-Center.0-0-d6297178-tHotelswithFitnessCenter.Hotel-Filter-Destinations) - [Resorts & Hotels with Spas in Santa Cruz ](https://expedia.com/Destinations-In-Santa-Cruz-Spa-Hotel.0-0-d6297178-tSpaHotel.Hotel-Filter-Destinations) - [Hotels with smoking rooms in Santa Cruz ](https://expedia.com/Destinations-In-Santa-Cruz-Hotels-With-Smoking-Rooms.0-0-d6297178-tHotelswithsmokingrooms.Hotel-Filter-Destinations) - [Hotels with Hot Tubs in Santa Cruz ](https://expedia.com/Destinations-In-Santa-Cruz-Hotels-With-Hot-Tubs.0-0-d6297178-tHotelsWithHotTubs.Hotel-Filter-Destinations) - [Hotels with Balconies in Santa Cruz ](https://expedia.com/Destinations-In-Santa-Cruz-Hotels-With-Balconies.0-0-d6297178-tHotelswithBalconies.Hotel-Filter-Destinations) - [Pet-friendly Hotels in Santa Cruz ](https://expedia.com/Destinations-In-Santa-Cruz-Pet-Friendly-Hotel.0-0-d6297178-tPetfriendlyHotel.Hotel-Filter-Destinations) - [Honeymoon Resorts & Hotels in Santa Cruz ](https://expedia.com/Destinations-In-Santa-Cruz-Honeymoon-Hotels.0-0-d6297178-tHoneymoonHotels.Hotel-Filter-Destinations) - [Hotels with Childcare in Santa Cruz ](https://expedia.com/Destinations-In-Santa-Cruz-Hotels-With-Childcare.0-0-d6297178-tHotelswithChildcare.Hotel-Filter-Destinations) - [Hotel Wedding Venues in Santa Cruz ](https://expedia.com/Destinations-In-Santa-Cruz-Wedding-Hotels.0-0-d6297178-tWeddingHotels.Hotel-Filter-Destinations) - [Cheap Hotels in Santa Cruz ](https://expedia.com/Destinations-In-Santa-Cruz-Cheap-Hotels.0-0-d6297178-tCheapHotels.Hotel-Filter-Destinations) - [Historic Hotels in Santa Cruz ](https://expedia.com/Destinations-In-Santa-Cruz-Historic-Hotel.0-0-d6297178-tHistoricHotel.Hotel-Filter-Destinations) - [Golf Hotels in Santa Cruz ](https://expedia.com/Destinations-In-Santa-Cruz-Golf-Hotel.0-0-d6297178-tGolfHotel.Hotel-Filter-Destinations) - [Hotels with Waterslides in Santa Cruz ](https://expedia.com/Destinations-In-Santa-Cruz-Hotels-With-Waterslides.0-0-d6297178-tHotelswithWaterslides.Hotel-Filter-Destinations) - [Hotels with Tennis Courts in Santa Cruz ](https://expedia.com/Destinations-In-Santa-Cruz-Hotels-With-Tennis-Courts.0-0-d6297178-tHotelswithTennisCourts.Hotel-Filter-Destinations) - [Hotels with an Indoor Pool in Santa Cruz ](https://expedia.com/Destinations-In-Santa-Cruz-Hotels-With-Indoor-Pool.0-0-d6297178-tHotelswithIndoorPool.Hotel-Filter-Destinations) - [Hotels with Kitchenettes in Santa Cruz ](https://expedia.com/Destinations-In-Santa-Cruz-Hotels-With-Kitchens.0-0-d6297178-tHotelswithKitchens.Hotel-Filter-Destinations) - [Hotels with a View in Santa Cruz ](https://expedia.com/Destinations-In-Santa-Cruz-Hotels-With-View.0-0-d6297178-tHotelswithView.Hotel-Filter-Destinations) - [Hotels with Suites in Santa Cruz ](https://expedia.com/Destinations-In-Santa-Cruz-Hotel-Suites.0-0-d6297178-tHotelSuites.Hotel-Filter-Destinations) - [Romantic Hotels in Santa Cruz ](https://expedia.com/Destinations-In-Santa-Cruz-Romantic-Hotel.0-0-d6297178-tRomanticHotel.Hotel-Filter-Destinations) - [Beach Hotels in Santa Cruz ](https://expedia.com/Destinations-In-Santa-Cruz-Beach-Hotel.0-0-d6297178-tBeachHotel.Hotel-Filter-Destinations) - [Adults Only Resorts & Hotels in Santa Cruz ](https://expedia.com/Destinations-In-Santa-Cruz-Adults-Only-Resorts.0-0-d6297178-tAdultsOnlyResorts.Hotel-Filter-Destinations) - [Hotels with a Swim-up Bar in Santa Cruz ](https://expedia.com/Destinations-In-Santa-Cruz-Hotels-With-Swimup-Bar.0-0-d6297178-tHotelswithSwimupBar.Hotel-Filter-Destinations) - [Casinos in Santa Cruz ](https://expedia.com/Destinations-In-Santa-Cruz-Casino-Hotel.0-0-d6297178-tCasinoHotel.Hotel-Filter-Destinations) - [Luxury Hotels in Santa Cruz ](https://expedia.com/Destinations-In-Santa-Cruz-Luxury-Hotel.0-0-d6297178-tLuxuryHotel.Hotel-Filter-Destinations) ### More Accommodation Types in Santa Cruz - [Lodges in Santa Cruz ](https://expedia.com/Santa-Cruz-Lodges.d6297178-aaLodges.Travel-Guide-Accommodation) - [Cabin Rentals in Santa Cruz ](https://expedia.com/Santa-Cruz-Cabins.d6297178-aaCabins.Travel-Guide-Accommodation) ### Hotels near Santa Cruz Airports - [El Trompillo Airport Hotels ](https://expedia.com/El-Trompillo-Airport-Hotels.0-aSRZ-0.Travel-Guide-Filter-Hotels) - [Viru Viru Intl. Airport Hotels ](https://expedia.com/Viru-Viru-Intl-Airport-Hotels.0-aVVI-0.Travel-Guide-Filter-Hotels) - [Apiahuaiqui Tumpa Airport Hotels ](https://expedia.com/Apiahuaiqui-Tumpa-Airport-Hotels.0-aMHW-0.Travel-Guide-Filter-Hotels) ### Popular national parks stays - [Hotels near Amboró National Park ](https://www.expedia.com/Amboro-National-Park-Hotels.0-l6098839-0.Travel-Guide-Filter-Hotels) - [Hotels near Noel Kempff Mercado National Park ](https://www.expedia.com/Noel-Kempff-Mercado-National-Park-Hotels.0-l6098841-0.Travel-Guide-Filter-Hotels) - [Hotels near Kaa-Iya National Park ](https://www.expedia.com/Kaa-Iya-National-Park-Hotels.0-l6350210-0.Travel-Guide-Filter-Hotels) - [Hotels near Carrasco National Park ](https://www.expedia.com/Carrasco-National-Park-Hotels.0-l553248635976357283-0.Travel-Guide-Filter-Hotels) ### Top theme parks in Santa Cruz - [Hotels close to AquaLand ](https://www.expedia.com/AquaLand-Hotels.0-l553248621532465362-0.Travel-Guide-Filter-Hotels) ### Explore more hotels - [Camino Real Hotel ](https://expedia.com/Santa-Cruz-Hotels-Camino-Real-Hotel.h444475.Hotel-Information) - [Ibis Santa Cruz DE LA Sierra ](https://expedia.com/Santa-Cruz-Hotels-Ibis-Santa-Cruz-DE-LA-Sierra.h87138613.Hotel-Information) - [Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel ](https://expedia.com/Santa-Cruz-Hotels-Los-Tajibos-Hotel-And-Convention-Center.h18758.Hotel-Information) - [Marriott Santa Cruz de la Sierra Hotel ](https://expedia.com/Santa-Cruz-Hotels-Marriott-Santa-Cruz-De-La-Sierra-Hotel.h21490226.Hotel-Information) - [Sun Hotel ](https://expedia.com/Santa-Cruz-Hotels-Sun-Hotel.h12836211.Hotel-Information) - [Novotel Santa Cruz De La Sierra ](https://expedia.com/Santa-Cruz-Hotels-Novotel-Santa-Cruz-De-La-Sierra.h69566260.Hotel-Information) - [Hampton by Hilton Santa Cruz/Equipetrol, Bolivia ](https://expedia.com/Santa-Cruz-Hotels-Hampton-By-Hilton-Santa-Cruz.h13179436.Hotel-Information) - [Premium Suites Deluxe Aparthotel Equipetrol ](https://expedia.com/Santa-Cruz-Hotels-Premium-Suites-Deluxe-Aparthotel-Equipetrol.h24404225.Hotel-Information) - [TRYP by Wyndham Santa Cruz ](https://expedia.com/Santa-Cruz-Hotels-TRYP-By-Wyndham-Santa-Cruz.h45617372.Hotel-Information) - [Delfines Collection Hotel By Mercure ](https://expedia.com/Santa-Cruz-Hotels-Delfines-Collection-Hotel-By-Mercure.h90301892.Hotel-Information) [See a list of all hotels in Santa Cruz](https://expedia.com/All-Santa-Cruz-Hotels.d6297178.Travel-Guide-City-All-Hotels) ### Expedia's Latest Trends Hotels - [Resorts & Hotels with Spas in La Paz](https://expedia.com/Destinations-In-La-Paz-Spa-Hotel.0-0-d6297090-tSpaHotel.Hotel-Filter-Destinations) - [Hotels in Vallegrande](https://expedia.com/Vallegrande-Hotels.d6350207.Travel-Guide-Hotels) - [Extended Stay Hotels in Santa Cruz](https://expedia.com/Santa-Cruz-Hotels-Extended-Stay-Hotels.0-0-d6053940-tExtendedStayHotels.Travel-Guide-Filter-Hotels) - [Golf Hotels in La Paz](https://expedia.com/Destinations-In-La-Paz-Golf-Hotel.0-0-d6297090-tGolfHotel.Hotel-Filter-Destinations) - [Hotels in Santa Cruz](https://expedia.com/Santa-Cruz-Hotels.d6053940.Travel-Guide-Hotels) - [Hotels with Hot Tubs in Cochabamba](https://expedia.com/Destinations-In-Cochabamba-Hotels-With-Hot-Tubs.0-0-d6297089-tHotelsWithHotTubs.Hotel-Filter-Destinations) - [Luxury Hotels in Santa Cruz](https://expedia.com/Santa-Cruz-Hotels-Luxury-Hotel.0-0-d6053940-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [La Paz hotels](https://expedia.com/Destinations-In-La-Paz.d6297090.Hotel-Destinations) - [Family Hotels in Florida Province](https://expedia.com/Destinations-In-Florida-Province-Family-Hotel.0-0-d553248635975751209-tFamilyHotel.Hotel-Filter-Destinations) - [Hotels in Colinas del Urubo](https://expedia.com/Colinas-Del-Urubo-Hotels.d6349680.Travel-Guide-Hotels) - [Resorts & Hotels with Spas in Potosi](https://expedia.com/Destinations-In-Potosi-Spa-Hotel.0-0-d6297171-tSpaHotel.Hotel-Filter-Destinations) Flights - [Flights to Oruro](https://expedia.com/Destinations-In-Oruro.d553248628939824197.Flight-Destinations) - [Flights to Chuquisaca](https://expedia.com/Destinations-In-Chuquisaca.d6053936.Flight-Destinations) - [Cheap Flights to Santa Cruz](https://expedia.com/Cheap-Flights-To-Santa-Cruz.d6053940.Travel-Guide-Flights) - [Roboré Flights](https://expedia.com/lp/flights/3000408084/flights-from-robore) - [Flights to La Paz](https://expedia.com/Destinations-In-La-Paz.d6297090.Flight-Destinations) Cars - [suv Car Rentals in Santa Cruz](https://expedia.com/SUV-Car-Rentals-In-Santa-Cruz.d6053940-tSUV.Car-Rental-Guide-Class) - [Car rental Santa Cruz Airport (VVI)](https://expedia.com/Car-Rentals-In-Viru-Viru-Intl.d6033004.Car-Rental-Guide) - [Car rentals in Santa Cruz](https://expedia.com/Car-Rentals-In-Santa-Cruz.d6053940.Car-Rental-Guide) Activities - [Things to do in La Paz](https://expedia.com/Things-To-Do-In-La-Paz.d6297090.Travel-Guide-Activities) Packages - [Santa Cruz Zoo](https://expedia.com/Santa-Cruz-Zoo-Santa-Cruz.d6098836.Vacation-Attraction) - [Noel Kempff Mercado National Park](https://expedia.com/Noel-Kempff-Mercado-National-Park-Santa-Cruz.d6098841.Vacation-Attraction) - [Santa Cruz Vacation](https://expedia.com/Santa-Cruz.d6053940.Destination-Travel-Guides) - [Cochabamba Vacation](https://expedia.com/Cochabamba.d6297089.Destination-Travel-Guides) Vacation Rentals - [Beni Vacation Rentals](https://expedia.com/Destinations-In-Beni.d6297087.Vacation-Rental-Destinations) General - [Visit Cochabamba](https://expedia.com/Cochabamba.dx6297089) - [Visit La Paz](https://expedia.com/La-Paz.dx6297090) - [Visit Jesuit Missions Circuit](https://expedia.com/Jesuit-Missions-Circuit.dx3000655727) - [Visit Santa Cruz](https://expedia.com/Santa-Cruz.dx6053940) - [Visit Tarija](https://expedia.com/Tarija.dx6297175) ## Frequently asked questions ### How much do hotels in Santa Cruz cost? ### When is the best time to go to Santa Cruz? ### Are there any luxury hotels in Santa Cruz? ### What are the top all-inclusive hotels in Santa Cruz? ### How can I find cheap hotels in Santa Cruz? ### What are the best hotels in Santa Cruz for families? ### Why should I book my Santa Cruz hotel with Expedia? ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save even more - 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