East Prairie, MO
Travel Guide
Visit East Prairie
Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner Sikeston MO
$90 nightly
The price is $103 total per night from Dec 29 to Dec 30
$103 total
Dec 29 - Dec 30
Total with taxes and fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,004 reviews)
Everything was well done
Reviewed on Dec 18, 2025
Hampton Inn Sikeston
1240 Commerce Drive Sikeston MO
$98 nightly
The price is $110 total per night from Jan 4 to Jan 5
$110 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Stay at this hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Central ...
8.8/10 Excellent! (449 reviews)
Everything we just lovely
Reviewed on Dec 20, 2025
Best Western Plus Sikeston
120 S Interstate Drive Sikeston MO
$76 nightly
The price is $86 total per night from Dec 29 to Dec 30
$86 total
Dec 29 - Dec 30
Total with taxes and fees
Stay at this hotel in Sikeston. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...
8.2/10 Very Good! (1,003 reviews)
Great stay, everything was clean and comfortable.
Reviewed on Dec 20, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
3 bedroom house on Reelfoot Lake, perfect for families, fisherman and hunters
Hornbeak TN
Stay at this vacation home in Hornbeak. Enjoy laundry facilities. Popular attractions Willow Towhead and Rat Island are located nearby.
The house was exaclty what we needed. It had everything we needed. We will be back. Great set up for a large group.
Reviewed on Dec 7, 2025
Log Cabin.
Hornbeak TN
Stay at this cabin in Hornbeak. Enjoy free WiFi, laundry facilities, and patios. Popular attractions Lake Isom National Wildlife Refuge and Willow Towhead are ...
9/10 Wonderful! (32 reviews)
The cabin is beautiful! Had no issues at all. Slept all 14 of us easily and could have slept more. The pond was the kids favorite, loved fishing out of it.
Reviewed on Sep 2, 2025
Come and relax at the Refuge at beautiful Reelfoot Lake!
Hornbeak TN
Enjoy free WiFi, laundry facilities, and patios. Popular attractions Willow Towhead and Rat Island are located nearby.
9.2/10 Wonderful! (23 reviews)
Great place
Reviewed on Dec 11, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular places to visit
Big Oak Tree State Park
You can take time to visit Big Oak Tree State Park during your travels to East Prairie. While you're in the area, wander around the parks.
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- Mississippi River
- Reelfoot Lake
- Ohio River
- Reelfoot Lake State Park
- Discovery Park of America
- Ohio River Valley
- Columbus-Belmont State Park
- New Madrid Historical Museum
- Marston Community Center
- Sikeston Depot Museum
- Central Park
- Campbell's Point
- Union City Masquerade Theatre
- Hunter-Dawson State Historic Site
- Fort Defiance State Park
- Graham Park
