East Prairie, MO
Travel Guide
Visit East Prairie
Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner Sikeston MO
$111 nightly
The price is $128 total per night from Jul 6 to Jul 7
$128 total
Jul 6 - Jul 7
Total with taxes and fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.6/10 Exceptional! (1,004 reviews)
"Quick check-in. Room was very clean and nice. Staff was helpful. Would definitely stay here again."
Reviewed on Jun 28, 2026
Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr Sikeston MO
$68 nightly
The price is $78 total per night from Jul 1 to Jul 2
$78 total
Jul 1 - Jul 2
Total with taxes and fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.2/10 Good! (1,001 reviews)
"Rooms are nice and clean although fixtures could be updated. There is no central air and heat, room is cooled by a wall unit. Room was extremely hot when I first entered."
Reviewed on Jun 24, 2026
Best Western Plus Sikeston I-55
120 S Interstate Drive Sikeston MO
$85 nightly
The price is $97 total per night from Jul 26 to Jul 27
$97 total
Jul 26 - Jul 27
Total with taxes and fees
Stay at this hotel in Sikeston. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...
8.4/10 Very Good! (1,004 reviews)
"The staff are really nice and friendly. Breakfast is very good too. Pretty close to a convenience store. Only problem was the musty smell through the hallways and into the room. We had to fan out the room before staying inside for too long. We also saw a dead cockroach on the window."
Reviewed on Jun 28, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Duck Hunting, Fishing or Relaxing Family Vacation
Hornbeak TN
Stay at this vacation home in Hornbeak. Enjoy a garden, laundry facilities, and patios. Popular attractions Willow Towhead and Rat Island are located ...
10/10 Exceptional! (233 reviews)
"Everything was wonderful and very peaceful, fishing was a little off. But we had a great time."
Reviewed on Jun 22, 2026
Buddy's Reel' Em Inn 2 Bd 1 Bath home on Reelfoot Lake. Sleeps 6.
Hornbeak TN
Stay at this vacation home in Hornbeak. Enjoy free WiFi, a garden, and laundry facilities. Popular attractions Willow Towhead and Rat Island are located ...
Come and relax at the Refuge at beautiful Reelfoot Lake!
Hornbeak TN
Enjoy free WiFi, laundry facilities, and patios. Popular attractions Willow Towhead and Rat Island are located nearby.
9.6/10 Exceptional! (33 reviews)
"Second time to stay here. Will definitely be back! Great location and amazing view! Clean & comfy!"
Reviewed on Jun 6, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular East Prairie attractions
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- Visit Sikeston
- Visit Bragg City
- Visit Malden
- Visit Dutchtown
- Visit New Madrid
- Visit Steele
- Visit Poplar Bluff
- Visit Wappapello
- Visit Gideon
- Visit Cape Girardeau
- Visit Risco
- Visit Dexter
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- Visit Kennett
- Visit Hayti
- Visit Portageville
- Visit Qulin
- Visit Jackson
- Charleston Vacations
- Visit Caruthersville
- Visit Charleston
- Visit Bernie
- Visit Catron
- Visit Oran
- Visit Marble Hill
- Mississippi River
- Ohio River
- Reelfoot Lake
- Reelfoot Lake State Park
- Discovery Park of America
- Ohio River Valley
- Columbus-Belmont State Park
- Sikeston Depot Museum
- Central Park
- Union City Masquerade Theatre
- Fort Defiance State Park
- Marston Community Center
- Campbell's Point
- New Madrid Historical Museum
