These East Prairie insights are based on real traveler data from Expedia, aggregated using AI to help you plan your trip. Updated: .

Find hotels in East Prairie, MO from $63
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Our top choices for East Prairie hotels




1. Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MO



2. Hampton Inn Sikeston
Hampton Inn Sikeston



3. Best Western Plus Sikeston I-55
Best Western Plus Sikeston I-55



4. Sleep Inn at Discovery Park of America
Sleep Inn at Discovery Park of America



5. Days Inn and Suites by Wyndham Sikeston
Days Inn and Suites by Wyndham Sikeston



6. Fairfield Inn & Suites by Marriott Sikeston
Fairfield Inn & Suites by Marriott Sikeston



7. Holiday Inn Express & Suites Sikeston Southwest by IHG
Holiday Inn Express & Suites Sikeston Southwest by IHG



8. Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)



9. The Riverstone Hotel Charleston-Sikeston
The Riverstone Hotel Charleston-Sikeston



10. Reelfoot Lake Inn
Reelfoot Lake Inn



11. Holiday Inn Express & Suites Union City by IHG
Holiday Inn Express & Suites Union City by IHG



12. Great location just across the street from Reelfoot Lake close to boat ramps
Great location just across the street from Reelfoot Lake close to boat ramps



13. Hampton Inn Union City
Hampton Inn Union City



14. Super 8 by Wyndham Sikeston/Miner Area
Super 8 by Wyndham Sikeston/Miner Area



15. Quality Inn Union City US 51
Quality Inn Union City US 51



16. TownePlace Suites by Marriott Sikeston
TownePlace Suites by Marriott Sikeston



17. Super 8 by Wyndham Charleston/Sikeston East MO
Super 8 by Wyndham Charleston/Sikeston East MO



18. Dave shallow lake lodge at reelfoot lake 2 story cabin 14 lakefront property
Dave shallow lake lodge at reelfoot lake 2 story cabin 14 lakefront property



19. Country Hearth Inn & Suites Union City
Country Hearth Inn & Suites Union City



20. Hospitality House Union City I 69 / US 51
Hospitality House Union City I 69 / US 51Where to stay in and around East Prairie



Sikeston
For travelers looking for a memorable trip, Sikeston offers a delightful blend of outdoor adventures and cultural experiences. Just a short drive from East Prairie, this city features attractions like the Sikeston Depot Museum and Central Park, perfect for exploring art and nature. With options for family fun, business gatherings, or romantic getaways, Sikeston's recreational area and nearby national state park cater to a variety of interests. Choosing Sikeston as your home base ensures easy access to these experiences and a welcoming atmosphere for all visitors.
Pinhook
Experience the charm of Pinhook, a wonderful hub for families and nature enthusiasts seeking an affordable getaway. This quaint village in East Prairie offers easy access to attractions like Big Oak Tree State Park, where outdoor adventures await, as well as the New Madrid Historical Museum, perfect for history buffs. Be sure to check out the City of Miner Convention Center for local events. With its strategic location, Pinhook is a smart choice for your next vacation stay.
Anniston
Make the most of your visit by staying in Anniston, a haven for families and nature enthusiasts thanks to its variety of outdoor activities and historic sites. Travelers will enjoy exploring the urban park and the nearby Columbus-Belmont State Park, while also having access to shopping and the City of Miner Convention Center for events. Located about 5 miles from East Prairie, Anniston offers a great blend of city life and natural beauty, making it an excellent choice for your stay.


Charleston
Charleston stands out as a prime spot for travelers seeking a blend of business and family-friendly experiences. Nestled about 10 miles from East Prairie, this charming city offers access to a national state park, a scenic lake, and a historic venue, making it perfect for outdoor adventures. Visitors can explore the City of Miner Convention Center, the Front Street Studio & Art Gallery, and the Sikeston Depot Museum. Charleston is a smart choice for your next getaway.
Bertrand
Travelers visiting the area often choose Bertrand, especially families and nature enthusiasts seeking close proximity to various outdoor activities. With its stunning scenery, Bertrand offers access to a beautiful national state park, a tranquil lake, and lush forests for exploration. Visitors can enjoy local attractions like the City of Miner Convention Center, Sikeston Depot Museum, and Central Park. Located about 10 miles from East Prairie, Bertrand is a smart hotel booking choice for those looking to immerse themselves in the great outdoors.
Stay near popular attractions in and around East Prairie
Big Oak Tree State Park
Sikeston Depot Museum
Central Park
Columbus-Belmont State Park
New Madrid Historical Museum
Hunter-Dawson State Historic Site
Front Street Studio & Art Gallery
Fort Defiance State Park
Learn more about East Prairie
Discover local heritage at the East Prairie Historical Museum, where artifacts tell the story of this Mississippi County town. Join the community for the annual Tour de Corn cycling event or explore nearby Big Oak Tree State Park for impressive ancient trees and wildlife viewing.
See all hotels in East Prairie
Top East Prairie Hotel Reviews
Reelfoot Lake Inn
"clean room, nice lake view, very quiet area. Just a good decent place to stay. Not a fancy 5 star hotel, but well worth it to me. Great place....Thanks!"
Quality Inn Union City US 51
"Pros: Excellent staff,Room was very spacious with a comfy bed and very quiet atmosphere Cons:Around edges of room floor was dirty.Wifi is awful and needs to be updated to better Internet service."
Sleep Inn at Discovery Park of America
"The room was clean and had plenty of room for two adults. Breakfast was fine and kitchen staff very helpful. Same with the desk staff at check-in and check-out. We had some questions about the television, which were quickly resolved. Plenty of parking, pretty scenery, and lots of nearby activities that we unfortunately didn't have time to enjoy. Will stay again when we're in the area."
Best Western Plus Sikeston I-55
"This place was very clean. We were given a 2nd floor room. I asked if there was an elevator. Yes. When we brought our things in to go to our room, we found the elevator was temporarily out of order. My friend cannot climb stairs. We were immediately given a 1st floor room close to an entrance near handicap parking. The room was clean. Comfortable beds. Good shower and tub. Excellent breakfast. I've never been to Sikeston before, but if I go again, I'll stay here."
Super 8 by Wyndham Sikeston/Miner Area
"Staff were friendly, room was nice and clean, the breakfast was delicious. Of the three hotels on this trip this was the best one."
Hampton Inn Sikeston
"👍"
For Larger Groups Up To 24, Right on Reelfoot Lake--Private Dock And Pier.
"Lake view clean room"
More cheap stays in East Prairie

Days Inn and Suites by Wyndham Sikeston

Sleep Inn at Discovery Park of America

Best Western Plus Sikeston I-55

Holiday Inn Express & Suites Sikeston Southwest by IHG

Hampton Inn Sikeston

Holiday Inn Express & Suites Union City by IHG
Hotels in East Prairie with star-rating

3 Star Hotels

2 Star Hotels
Find out more about East Prairie
Top reasons to visit East Prairie
- Outdoor Adventures: East Prairie is perfect for hiking, camping, and exploring scenic recreational areas, making it an ideal destination for nature lovers.
- Dog Park Fun: Enjoy quality time with your furry friends at local dog parks, providing a great space for pets and their owners to relax and socialize.
- Cultural Experiences: Delve into local history through museums and art galleries, offering a glimpse into the region's rich heritage.
- Family-Friendly Activities: Enjoy a welcoming atmosphere with various excursions suitable for all ages, ensuring fun for the whole family.
- Comfortable Accommodations: Choose from a range of pet-friendly hotels and motels that cater to both business and leisure travelers.
Find great hotels near East Prairie
Discover a range of comfortable accommodations in East Prairie, Missouri, perfect for every type of traveler. From pet-friendly hotels to welcoming motels, you'll find options that cater to business travelers and those seeking an inclusive experience. Whether you're looking for hotels near East Prairie or the best motels in the area, you can enjoy a relaxing stay surrounded by Southern hospitality.
- Days Inn and Suites by Wyndham Sikeston: Located 11 miles from East Prairie, Days Inn and Suites by Wyndham Sikeston is the perfect budget-friendly option for travelers seeking a comfortable stay without breaking the bank. This hotel caters to both business and leisure guests, allowing pets on-site, making it an excellent choice for pet owners. With amenities such as free Wi-Fi, complimentary breakfast, and a pool, guests can enjoy a pleasant stay. The hotel’s pet policy includes specific restrictions, ensuring a welcoming environment for all furry companions.
- Drury Inn & Suites Sikeston, MO: With a stellar guest rating of 9.4 out of 10, Drury Inn & Suites Sikeston, MO is a 3-star hotel that stands out for families and business travelers alike. Situated 11 miles from East Prairie, this hotel offers a range of child-friendly amenities, including free cribs. Its pet-friendly policy allows for furry family members to join the fun, with certain restrictions in place. Guests can indulge in complimentary breakfast, evening snacks, and a welcoming atmosphere that makes every stay memorable.
- Best Western Plus Sikeston I-55: Rated 8.4 out of 10, Best Western Plus Sikeston I-55 is another excellent budget-friendly choice located 11 miles from East Prairie. This hotel ensures a cozy stay for pet owners, with specific pet policies that allow pets on the property. Guests can enjoy amenities like free Wi-Fi, hot breakfast, and a fitness center. Ideal for travelers looking for convenience and comfort, this hotel combines quality service with excellent facilities, ensuring a pleasant experience for all who stay.
Where to stay near East Prairie
East Prairie, Missouri, is a hidden gem for outdoor enthusiasts and adventure seekers alike. Nestled in a serene landscape, this charming city offers family-friendly excursions and a welcoming atmosphere. Explore the beautiful prairies and enjoy the friendly local culture. Nearby destinations provide additional opportunities for relaxation and exploration, making East Prairie an ideal base for discovering the scenic wonders of the region. Get ready for an unforgettable vacation experience.
- Sikeston: Located 13 miles from East Prairie, Sikeston is a vibrant city that offers a mix of outdoor and family-friendly activities. Visitors often flock here for its recreational areas and arena entertainment facilities. The city’s appeal peaks during the summer months, making it a great spot for those looking to enjoy warm-weather adventures. Sikeston is also home to a shopping center that caters to various tastes. Nature enthusiasts will appreciate the nearby lake and national state park, providing ample opportunities for hiking, fishing, and relaxation in picturesque surroundings.
- Anniston: Just 5 miles from East Prairie, Anniston is a charming city that invites families and outdoor lovers alike. While its visitor numbers remain steady year-round, the summer months see the most activity. Here, you can explore educational venues, enjoy shopping at local centers, and take advantage of the city's urban parks. Anniston's attractions also include a museum that showcases the area’s rich history, making it an excellent destination for those interested in culture and exploration. Its welcoming atmosphere and convenient amenities ensure a pleasant travel experience.
- Charleston: Situated 10 miles away from East Prairie, Charleston is an adventurous city that captivates visitors with its stunning scenery. Popular for outdoor enthusiasts, the city offers a variety of recreational areas and a lively shopping center. Travelers are drawn to Charleston for its outdoor adventures, particularly in the spring and summer months. The nearby national state park and lake provide a beautiful backdrop for hiking and water activities, while historic sites highlight the region's past. Whether you're seeking adventure or relaxation, Charleston has something for everyone.
Things to do in East Prairie
East Prairie, Missouri, is perfect for an outdoor adventure getaway, offering a range of activities such as exploring scenic recreational areas, enjoying time at a dog park, or hitting the links at a local golf course. Whether you're looking for weekend camping options or simply a relaxing trip, East Prairie provides the ideal backdrop for memorable outdoor experiences and fun weekend trips.
Shopping
In East Prairie, visit local shops for unique gifts and souvenirs. If you're up for a drive, check out the Sikeston Factory Outlet Stores, about 12 miles away, offering a variety of brand-name merchandise at discounted prices, perfect for finding that special item.
Recreation
In East Prairie, rejuvenate at the Healing Touch Wellness Center, where you can indulge in holistic therapies and massage treatments tailored to your needs. For outdoor fun, explore local parks for hiking and fishing, embracing nature's tranquility while enjoying the area's serene landscapes.
Adventure
East Prairie offers thrilling outdoor activities, including fishing at Lake Coutra, where you can reel in bass and catfish. Explore the nearby Mississippi River for kayaking adventures, or take a scenic hike in the surrounding woodlands, perfect for spotting local wildlife and enjoying the natural beauty.
Nightlife
In East Prairie, you can enjoy a laid-back nightlife atmosphere with local bars and eateries offering live music and friendly vibes. The Prairie Dog Saloon is popular for its casual setting and drinks, while nearby events often showcase regional talent, creating a charming community feel.
*Distances are measured in a straight line; actual driving distances may vary depending on the route.Booking tips and Expedia advantages for East Prairie
- The most and least expensive months on average to stay in a hotel: The cheapest months to stay in East Prairie are December to February, where the prices are slightly lower. This is in comparison to April, June and August, where prices are slightly higher.
- The most and least expensive days on average to stay in a hotel: The least expensive day to stay in East Prairie is Sunday. The most expensive day to stay in East Prairie is Saturday.
- Find cheap hotels on Expedia: Certainly. Here's a paraphrased version of the text in a trusted and attentive tone:Expedia's user-friendly search tool enables you to set your budget, choose your desired location, and much more. You can easily arrange your results to display hotels from the most affordable to the higher-priced options, ensuring you find the best deals first. Additionally, you have the option to refine your search by hotel type. For instance, by selecting the Eco-certified filter, you'll be shown a selection of sustainable and environmentally-friendly hotels that are available for booking.
- Consider bundling your trip: You can save money by combining your hotel stay in East Prairie with your flights and activities through an Expedia package deal.
Find the best attractions near East Prairie
East Prairie, Missouri, offers an exciting blend of outdoor adventures and cultural experiences for tourists. Visitors can explore nearby national and state parks, delve into local history at museums, and appreciate art at nearby galleries. Whether you're seeking scenic landscapes or rich cultural insights, East Prairie provides a variety of attractions that cater to every traveler's interests, ensuring a memorable vacation.
- Columbus-Belmont State Park: Discover stunning landscapes and outdoor adventures at this beautiful state park, located 15 miles from East Prairie. Enjoy hiking, picnicking, and exploring the rich history of the area, including its Civil War significance.
- Central Park: This urban gem, situated 13 miles away, is perfect for families looking to relax and enjoy the outdoors. Stroll through lush green spaces, partake in recreational activities, and soak in the vibrant city atmosphere.
- Sikeston Depot Museum: Located 13 miles from East Prairie, this art museum offers a glimpse into local culture and history. Explore fascinating exhibits that showcase the region's heritage and artistic talent.
Best time to go to East Prairie
The best time to visit East Prairie is dependent on what kind of holiday you are seeking. July is its hottest month on average. At this time, visitor numbers are moderately high and weather is mostly sunny with light rain. January is its coolest month on average. At this time, visitor numbers are moderately high and weather is mostly sunny with light rain.
Calendar Month | Temperature | Precipitation | Cloudiness | Occupancy | Pricing |
| January | 36.3°F (2.4°C) | Light Rain | Mostly Sunny | Moderately High | Slightly Low |
| February | 39.4°F (4.1°C) | Light Rain | Mostly Sunny | Average | Slightly Low |
| March | 49.5°F (9.7°C) | Light Rain | Mostly Sunny | Average | Average |
| April | 58.5°F (14.7°C) | Light Rain | Mostly Sunny | Average | Slightly High |
| May | 68.2°F (20.1°C) | Light Rain | Mostly Sunny | Average | Average |
| June | 77.0°F (25.0°C) | Light Rain | Mostly Sunny | Moderately High | Slightly High |
| July | 79.5°F (26.4°C) | Light Rain | Mostly Sunny | Moderately High | Average |
| August | 77.5°F (25.3°C) | Light Rain | Mostly Sunny | Average | Slightly High |
| September | 72.1°F (22.3°C) | Light Rain | Mostly Sunny | Average | Average |
| October | 60.8°F (16.0°C) | Light Rain | Mostly Sunny | Moderately Low | Average |
| November | 48.6°F (9.2°C) | Light Rain | Mostly Sunny | Moderately Low | Average |
| December | 41.2°F (5.1°C) | Light Rain | Mostly Sunny | Moderately Low | Slightly Low |
The nearest major airports for your trip to East Prairie
Traveling to East Prairie, Missouri, can be conveniently done via several nearby airports. Jackson, TN (MKL-McKellar-Sipes Regional) is 85 miles away, with excellent hotel options such as the 4-star DoubleTree by Hilton Hotel Jackson and the 3-star Hilton Garden Inn, both 5 miles from the airport. The Cape Girardeau, MO (CGI-Cape Girardeau Municipal) airport is a closer option at 32 miles, featuring hotels like the Drury Plaza Hotel and Drury Inn & Suites, both within 6 miles. Additionally, Marion, IL (MWA-Williamson County Regional) is 70 miles away, offering the Drury Inn & Suites Marion just 2 miles from the airport for easy access.
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