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Santee Vacation Rentals

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Check prices for these dates

In two weeks
Jul 24 - Jul 26
In two months
Sep 4 - Sep 6
In three months
Oct 2 - Oct 4
In four months
Oct 30 - Nov 1

Our top choices for Santee vacation rentals

Lobby

The Bohemian Bungalow near Main Street in Scenic Verdigre, Nebraska

The Bohemian Bungalow near Main Street in Scenic Verdigre, Nebraska
Verdigre
10.0 out of 10, Exceptional, (11 reviews)
"Great place to stay! "
United States
Cole K.
$194 nightly
The price is $217
Jul 11 - Jul 12
Total with taxes and fees
The Bohemian Bungalow near Main Street in Scenic Verdigre, Nebraska
Interior

Newly Remodeled Creekside Bungalow on 3 acres with private Beach/Creek access

Newly Remodeled Creekside Bungalow on 3 acres with private Beach/Creek access
Verdigre
10.0 out of 10, Exceptional, (3 reviews)
"It’s a cute little house! It’s easy to find but far enough away from people. Definitely going to save it for when I’m ever out that way! "
United States
Loraine C.
$219 nightly
The price is $242
Jul 12 - Jul 13
Total with taxes and fees
Newly Remodeled Creekside Bungalow on 3 acres with private Beach/Creek access
Exterior

Modern Lewis and Clark lake home with lake views and 3 min drive to the beach!

Modern Lewis and Clark lake home with lake views and 3 min drive to the beach!
Crofton
10.0 out of 10, Exceptional, (7 reviews)
"Super clean and everything was ready for us plenty of room for 10 of us to enjoy together "
United States
timothy B.
$1,060 nightly
The price is $1,171
Jul 13 - Jul 14
Total with taxes and fees
Modern Lewis and Clark lake home with lake views and 3 min drive to the beach!
Interior

Leather&Spruce - Luxury Lake area fun funky home with amenities. Great for 2-18!

Leather&Spruce - Luxury Lake area fun funky home with amenities. Great for 2-18!
Yankton
10.0 out of 10, Exceptional, (23 reviews)
"Excellent set up, clean and furnished beautifully. "
United States
Wade P.
$833 nightly
The price is $875
Jul 15 - Jul 16
Total with taxes and fees
Leather&Spruce - Luxury Lake area fun funky home with amenities. Great for 2-18!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santee Hotel Reviews

Lewis and Clark Resort

Lewis and Clark Resort

8/10 Good
"Fishing trip for three adult men. Good for what we was after. Good place for family stay. Only the one bathroom would be the only complaint if more people were along. Great view of lake."
Mark 3-night trip
Posted 3 days ago
Lewis and Clark Resort

Find out more about Santee

Everything you need to know about Santee vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Santee vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santee vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Santee vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Santee. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Santee in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $242 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Santee rentals

At Expedia, we put the best Santee vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Santee rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santee vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santee. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Can I find a vacation rental in Santee?

Yes, we give you a choice of vacation rentals near top points of interest in Santee, or you can select a more remote option if you'd like a relaxing place to stay.

What are some of the best vacation rentals in Santee?

Modern Lewis and Clark lake home with lake views and 3 min drive to the beach!: This vacation home rental outside of Santee is located near skiing and has a patio, a garden, and air-conditioning to put you at ease in your new surroundings.

What’s there to see and do in Santee?

While you're exploring the area, Lewis and Clark Lake and Lewis and Clark Recreation Area are a couple of picturesque spots to get outside and enjoy nature. Niobrara State Park and Lewis and Clark Lake State Recreation Area are a couple of places you'll find in the larger area.

What’s a vacation rental in Santee like?

A vacation rental is a private property you can book for a few weeks or just a few days in Santee. Vacation rentals offer amenities like WiFi and washers and dryers so you'll have all the comforts of home. If you're concerned about a clean environment, a vacation rental can offer a sense of privacy away from public hotel elevators and busy front desks while still allowing you the enjoyment of travel. You'll also get more space in a vacation rental than in a traditional hotel, which is another reason why a vacation rental is a great choice for a family getaway.