
Find hotels in Santee, NE from $97
Go beyond your typical stay in Santee
Pet friendly
Apartment
Condo
Family friendly
Cabin
Waterpark
Check prices for these dates
Tonight
Sep 20 - Sep 21Tomorrow
Sep 21 - Sep 22Next weekend
Sep 25 - Sep 27In two weeks
Oct 2 - Oct 4Our top choices for Santee hotels




1. Lewis and Clark Resort
Lewis and Clark ResortYankton
Melissa
$92 nightly
$97 total
Oct 13 - Oct 14
Total with taxes and fees




2. Comfort Inn Yankton SD
Comfort Inn Yankton SDYankton
Vanessa
$95 nightly
$105 total
Oct 11 - Oct 12
Total with taxes and fees




3. The Historic Argo Hotel
The Historic Argo HotelCrofton
Deborah
$185 nightly
$207 total
Sep 28 - Sep 29
Total with taxes and fees




4. Peaceful bed & breakfast with AC in charming Crofton
Peaceful bed & breakfast with AC in charming CroftonCrofton
$198 nightly
$222 total
Sep 21 - Sep 22
Total with taxes and fees




5. Family-friendly log cabin style house by Lewis & Clark Lake at DJ's Resort
Family-friendly log cabin style house by Lewis & Clark Lake at DJ's ResortYankton
Linda




6. Welcoming bed & breakfast with AC in charming Crofton
Welcoming bed & breakfast with AC in charming CroftonCrofton
Welcoming bed & breakfast with AC in charming CroftonStay near popular attractions around Santee
Nestled in the heart of nature, Santee offers a perfect escape for outdoor enthusiasts and romance seekers alike. With stunning parks, serene lakes, and breathtaking scenery, you'll find countless opportunities for family adventures and eco-friendly experiences that create lasting memories.
Niobrara State Park
10.0/10 (3 reviews)
Ideal for outdoor enthusiasts, Niobrara State Park offers breathtaking scenery and adventure in a serene setting. Located about 12 miles from Santee, this park is perfect for exploring nature while providing easy access to nearby attractions, making it a convenient base for your vacation.
Lewis and Clark Lake
9.2/10 (57 reviews)
Experience the best of outdoor adventure at Lewis and Clark Lake, a scenic destination perfect for couples and families alike. Enjoy the romantic atmosphere, breathtaking views, and beach vibes that make this lake a must-visit. Located about 7 miles from Santee, it offers convenient access for a memorable getaway.
Bloomfield Recreation Area
Ideal for families seeking outdoor adventures, Bloomfield Recreation Area offers a serene setting with eco-friendly vibes. Located about 11 miles from Santee, this park features lush landscapes and recreational opportunities. Staying nearby provides easy access to a peaceful retreat for nature lovers.
Pebble Beach
No trip is complete without a visit to Pebble Beach, a perfect spot for families seeking a relaxing day by the water. With its inviting beach vibes, this destination offers a unique experience for those looking to unwind. Located about 13 miles from Santee, it’s an easy excursion that enhances your stay in the area.
Sioux Council Boy Scout Reservation
Discover the appeal of this family-friendly park, the Sioux Council Boy Scout Reservation, located in Tabor, South Dakota. Known for its outdoor and eco-friendly vibes, it offers a perfect setting for nature lovers. Situated about 13 miles from Santee, it's a convenient stop for a refreshing getaway.
Lesterville Recreation Area
For families seeking outdoor adventures, Lesterville Recreation Area offers a picturesque escape with its eco-friendly vibes and ample recreational opportunities. Situated about 14 miles from Santee, this park is perfect for enjoying nature and creating lasting memories, making it a convenient choice for your getaway.
Top Santee Hotel Reviews
Lewis and Clark Resort
10/10 Excellent
"We got there early was able to check in. The room was cute and clean. The pet fee was lower then other place we have been. One down fall was they did not have the Big10 on TV. We would have stay another day if we could of watch our game."
Modern Lewis and Clark lake home with lake views and 3 min drive to the beach!
10/10 Excellent
"Everything was great!"
Fully furnished lake house with cozy spaces, full kitchen, and lake views.
10/10 Excellent
"Great location to host our company retreat! The house was spacious and offered plenty of room. Appreciated all the outdoor chairs available to use. We enjoyed sitting around the outdoor firepit at night."
Newly Remodeled Creekside Bungalow on 3 acres with private Beach/Creek access
10/10 Excellent
"Thank you for a pleasant short stay. Very nice place and location. Would stay again."
Lewis & Clark Trail Hideaway, SD side / 2 min to the lake / 10 min to Yankton.
8/10 Good
"rooms were clean, kitchen fully stocked, hot tub was in good condition. host was very quick to respond to questions. nice place"
HotTub, PingPong, Firepit, 2 LivingRooms just .67 mi to beach
10/10 Excellent
"Great property! Very well stocked. Amazing decor. Quiet neighborhood. Nice spaces for a large group to spread out."
Haven by the Lake
10/10 Excellent
"Amazing place to stay at, great access to the water, lots of space, overall great experience!"
Hunters & outdoor lovers charming 4-bedrm house - best Lewis & Clark lake view!
10/10 Excellent
"This property was amazing! Unbelievable views, well maintained, super clean and the hosts were amazing. Will be staying again!"
ThePinecone - luxury vacation rental awesome deck with view & amenities for 2-18
10/10 Excellent
"Such a beautiful view with a great open yard and huge deck to enjoy the view! We loved the beautiful kitchen and dining room space. The beds were comfortable and it was a wonderful space"
More cheap stays in Santee

Lewis and Clark Resort
43496 Shore Drive Yankton SD
$92 nightly
$97 total
Oct 13 - Oct 14
Total with taxes and fees
9/10 Wonderful! (338 reviews)
Hotels in Santee with star-rating

3 Star Hotels
9 properties

2 Star Hotels
1 properties
Frequently asked questions
Explore a world of travel with Expedia
- Motels in Lynch
- Guest Houses in Wausa
- Fordyce Hotels
- Wausa Hotels
- Cottages in Fordyce
- Plainview Hotels
- Cabin Rentals in Niobrara
- Cottages in Verdigre
- Cabin Rentals in Verdigre
- Bloomfield Hotels
- Cabin Rentals in Creighton
- Spencer Hotels
- Cottages in Hartington
- Cabin Rentals in Monowi
- Dixon Hotels
- Cabin Rentals in Verdel
- Vacation Homes in Wausa
- Vacation Homes in Monowi
- Cabin Rentals in Bloomfield
- Cabin Rentals in Hartington
- 3 Star Hotels in Wynot
- Newcastle Hotels
- Winside Hotels
- Orchard Hotels
- Apartments in Wausa
- Cabin Rentals in Osmond
- 2 Star Hotels in Lynch
- Knox County Hotels
- Hartington Hotels
- Cottages in Santee
- O'neill Hotels
- Butte Hotels
- Hoskins Hotels
- Apartments in Magnet
- Vacation Homes in Brunswick
- Cabin Rentals in Wausa
- Niobrara Hotels
- Vacation Homes in Plainview
- Cottages in Verdel
- Maskell Hotels
- 2 Star Hotels in Magnet
- Emmet Hotels
- Wynot Hotels
- Ewing Hotels
- Pierce Hotels
- Cottages in Monowi
- Crofton Hotels
- Osmond Hotels
- Vacation Homes in Bloomfield
- Monowi Hotels
- Concord Hotels
- Verdigre Hotels
- Cabin Rentals in Lynch
- Randolph Hotels
- 2 Star Hotels in Monowi
- Martinsburg Hotels
- Neligh Hotels
- Royal Hotels
- Hotels with a Pool in Crofton
- Guest Houses in Hartington
- Hotels near Cedar County Fairgrounds
- 3 Star Hotels in Bloomfield
- Flights from Fordyce
- Flights to Hartington
- Flights to Crofton
- Flights from Niobrara
- Flights to Bloomfield
- Flights from Osmond
- Flights to Creighton
- Flights to Verdigre
- Flights from Crofton
- Flights from Brunswick
- Flights from Lynch
- Flights from Magnet
- Flights from Wynot
- Flights from Bloomfield
- Flights to Osmond
- Flights to Niobrara
- Flights from Monowi
- Flights to Monowi