Business Hotels in South America from $77

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Our top choices for South America business-friendly hotels

Radisson Blu Plaza El Bosque Santiago

Radisson Blu Plaza El Bosque Santiago
4.0 star property
Las Condes
8.8 out of 10, Excellent, (1003)
"Clean room, comfortable bed, great breakfast, excellent customer service!!"
United States
Beatriz
$123 nightly
The price is $123
Dec 24 - Dec 25
Radisson Blu Plaza El Bosque Santiago

Grand Hyatt Sao Paulo

Grand Hyatt Sao Paulo
5.0 star property
Itaim Bibi
9.4 out of 10, Exceptional, (1003)
"Very nice room. "
United States
Reinaldo
$189 nightly
The price is $199
Jan 3 - Jan 4, 2026
Total with taxes and fees
Grand Hyatt Sao Paulo

Pullman Santiago Vitacura

Pullman Santiago Vitacura
5.0 star property
Vitacura
9.0 out of 10, Wonderful, (909)
"Clean and quiet"
United States
Nathan
$108 nightly
The price is $108
Jan 9 - Jan 10, 2026
Pullman Santiago Vitacura

NH Collection Medellín Royal

NH Collection Medellín Royal
5.0 star property
El Poblado
9.2 out of 10, Wonderful, (1002)
"excellent location, friendly staff, excellent food."
United States
Felix
$101 nightly
The price is $101
Jan 18 - Jan 19, 2026
NH Collection Medellín Royal

NM Lima Hotel

NM Lima Hotel
4.0 star property
San Isidro
9.2 out of 10, Wonderful, (1001)
"Excelent place, great food, nice people"
United States
Renato
$86 nightly
The price is $86
Dec 23 - Dec 24
NM Lima Hotel

Pullman Lima San Isidro

Pullman Lima San Isidro
4.0 star property
San Isidro
9.2 out of 10, Wonderful, (799)
"Everything was great about the hotel clean, the staff and amenities were all excellent."
United States
Nestor
$108 nightly
The price is $108
Jan 10 - Jan 11, 2026
Pullman Lima San Isidro

Hotel Plaza El Bosque Ebro

Hotel Plaza El Bosque Ebro
4.0 star property
Las Condes
9.0 out of 10, Wonderful, (1005)
"Simply a very pleasant hotel to stay at in a very nice area of town with plenty of great dining options nearby."
United States
Gerald
$116 nightly
The price is $116
Dec 26 - Dec 27
Hotel Plaza El Bosque Ebro

Hotel Madero Buenos Aires, WorldHotels Elite

Hotel Madero Buenos Aires, WorldHotels Elite
4.5 star property
Puerto Madero
9.2 out of 10, Wonderful, (1003)
"The staff is absolutely wonderful. Hotel is great too!"
United States
Anthony Miles
$220 nightly
The price is $223
Jan 4 - Jan 5, 2026
Hotel Madero Buenos Aires, WorldHotels Elite

Regal Pacific Buenos Aires

Regal Pacific Buenos Aires
4.5 star property
Microcentro
9.0 out of 10, Wonderful, (1005)
"Very good"
United States
Cindy
$112 nightly
The price is $115
Jan 19 - Jan 20, 2026
Regal Pacific Buenos Aires

GHL Hotel Capital

GHL Hotel Capital
4.0 star property
Fontibon
9.2 out of 10, Wonderful, (1363)
"Ir was really grat staying in this hotel"
United States
Julio
$77 nightly
The price is $77
Dec 23 - Dec 24
GHL Hotel Capital
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top South America Hotel Reviews

Frequently asked questions

Why book your business-friendly hotel in South America with Expedia?
Here at Expedia, our top task is to help you choose the perfect stay at the right price. From luxurious, corporate-friendly getaways to affordable hotels filled with handy amenities, you'll have your next work trip organized in just a few clicks.
How can I find cheap business-friendly hotels in South America?
When work takes you to South America, our "business friendly" filter will help you find the right hotel. From fast WiFi to meeting rooms and workspaces, they have the amenities you need to do your job. You can also narrow your search by your budget and preferred star rating to view the cheapest properties.