Cheap Flights to South America from $144

If you're planning a spontaneous trip to South America, you might find cheap last-minute airfares to your chosen destination, but there are a few tricks to help you land an awesome deal. When you book with Expedia, it's easy to compare prices for different carriers, cabin class, arrival and departure dates, and more to find the best ticket for your budget. Setting up a price alert is a simple way to keep track of fare variations for your preferred route. We're constantly updating our offers, so keep checking until you find the perfect deal!

South America is a huge continent, which means the most popular months can vary depending on each region and what you plan to see and do. September to November are often considered to be good months to visit. Several destinations, like Buenos Aires and Rio de Janeiro, experience mild, spring-like conditions. Summertime is high season in Patagonia, when hiking trails are easily accessible, and at the beaches of Colombia. Wherever you go, be sure to do some research beforehand. For example, July and August is usually peak time for Peru's Inca Trail, but it closes for maintenance in February. June to September is the ski season in Chile.

Many international carriers offer flights to South America from continental USA. They include American Airlines, Copa Airlines, LATAM Airlines and plenty more. The availability and prices of flights can vary according to each specific destination and the time of year you choose to fly. To see if your favorite airline flies a certain route, simply enter your departure and arrival airports into Expedia.

Thanks to an almost infinite list of cultural, historical and natural attractions, we've got a vacation to suit all types of visitor to South America. If you love city life, Buenos Aires is sure to impress with its tango shows, fascinating architecture and nightlife. Or, blend the pulsating urban vibe of Rio de Janeiro with its world-famous beaches and Carnival celebrations. Natural wonders dot the entire landscape of South America. Make time to visit Iguazu Falls, shared between Argentina and Brazil, and the Salar de Uyuni salt flats in Bolivia. For beaches, colonial architecture and an energetic culture, Cartagena, Colombia is a must. Outdoor adventure more your thing? Walk to the ancient Inca city of Machu Picchu and go on wilderness hikes in Chile's Torres del Paine National Park. Unforgettable encounters with exotic wildlife await in Ecuador's Galapagos Islands.

There are several airports to start a South American adventure, including Buenos Aires Ministro Pistarini International Airport (EZE), São Paulo-Guarulhos International Airport (GRU) and Lima Jorge Chavez International Airport (LIM). All offer connecting flights to both domestic and international destinations around the region.