$390 Cheap Flights from Des Moines (DSM) to Cuenca (CUE)

View $390 flight on Wed, Aug 20, 2025Opens in a new window

Popular airlines from Des Moines International Airport (DSM) to Cuenca (CUE-Mariscal Lamar)

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Cheap Flights from Des Moines to Cuenca (DSM-CUE)

Prices were available within the past 7 days and start at $390 for one-way flights and $1,286 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

United
Wed, Dec 17 - Tue, Jan 27
DSM
Des Moines
CUE
Cuenca
$1,286 Roundtrip, found 13 hours ago
$1,286
Roundtrip
found 13 hours ago
Select United flight, departing Wed, Dec 17 from Des Moines to Cuenca, returning Tue, Jan 27, priced at $1,286 found 13 hours ago
United
Wed, Dec 17 - Tue, Jan 27
DSM
Des Moines
CUE
Cuenca
$1,301 Roundtrip, found 13 hours ago
$1,301
Roundtrip
found 13 hours ago
Select United flight, departing Wed, Dec 17 from Des Moines to Cuenca, returning Tue, Jan 27, priced at $1,301 found 13 hours ago
United
Wed, Dec 17 - Tue, Jan 27
DSM
Des Moines
CUE
Cuenca
$1,306 Roundtrip, found 13 hours ago
$1,306
Roundtrip
found 13 hours ago
Select United flight, departing Wed, Dec 17 from Des Moines to Cuenca, returning Tue, Jan 27, priced at $1,306 found 13 hours ago
United
Wed, Dec 17 - Tue, Jan 27
DSM
Des Moines
CUE
Cuenca
$1,322 Roundtrip, found 13 hours ago
$1,322
Roundtrip
found 13 hours ago
Select United flight, departing Wed, Dec 17 from Des Moines to Cuenca, returning Tue, Jan 27, priced at $1,322 found 13 hours ago
United
Wed, Dec 17 - Tue, Jan 27
DSM
Des Moines
CUE
Cuenca
$1,431 Roundtrip, found 13 hours ago
$1,431
Roundtrip
found 13 hours ago
Select United flight, departing Wed, Dec 17 from Des Moines to Cuenca, returning Tue, Jan 27, priced at $1,431 found 13 hours ago
United
Wed, Dec 17 - Tue, Jan 27
DSM
Des Moines
CUE
Cuenca
$1,436 Roundtrip, found 13 hours ago
$1,436
Roundtrip
found 13 hours ago
Select United flight, departing Wed, Dec 17 from Des Moines to Cuenca, returning Tue, Jan 27, priced at $1,436 found 13 hours ago
United
Wed, Dec 17 - Tue, Jan 27
DSM
Des Moines
CUE
Cuenca
$1,451 Roundtrip, found 13 hours ago
$1,451
Roundtrip
found 13 hours ago
Select United flight, departing Wed, Dec 17 from Des Moines to Cuenca, returning Tue, Jan 27, priced at $1,451 found 13 hours ago
United
Wed, Dec 17 - Tue, Jan 27
DSM
Des Moines
CUE
Cuenca
$1,452 Roundtrip, found 13 hours ago
$1,452
Roundtrip
found 13 hours ago
Select United flight, departing Wed, Dec 17 from Des Moines to Cuenca, returning Tue, Jan 27, priced at $1,452 found 13 hours ago
LATAM Airlines Group
Tue, Aug 12 - Sat, Aug 16
DSM
Des Moines
CUE
Cuenca
$1,657 Roundtrip, found 3 days ago
$1,657
Roundtrip
found 3 days ago
Select LATAM Airlines Group flight, departing Tue, Aug 12 from Des Moines to Cuenca, returning Sat, Aug 16, priced at $1,657 found 3 days ago
Delta
Wed, Dec 17 - Tue, Jan 27
DSM
Des Moines
CUE
Cuenca
$1,677 Roundtrip, found 13 hours ago
$1,677
Roundtrip
found 13 hours ago
Select Delta flight, departing Wed, Dec 17 from Des Moines to Cuenca, returning Tue, Jan 27, priced at $1,677 found 13 hours ago
Flights from Des Moines (DSM) to Cuenca (CUE)
Origin airport
Des Moines Intl.
Destination airport
Mariscal Lamar
Airlines serving
LATAM Airlines Group
Roundtrip price
$1,285
Distance
3204 mi

Des Moines to Cuenca Flights

The cheapest times to fly from Des Moines to Cuenca

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Des Moines to Cuenca are during the month of December. You can find some of the cheapest flights from Des Moines to Cuenca with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Des Moines to Cuenca

Sunday is one of the best days to book for cheap flights from Des Moines to Cuenca: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Des Moines to Cuenca

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Des Moines to Cuenca in 2025. You can also book with separate airlines for your outbound and return journeys, from $390 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Des Moines to Cuenca flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Des Moines to Cuenca airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Des Moines Intl. Airport (DSM) to Mariscal Lamar Airport (CUE) cost?
Discover the latest flight deals from DSM to CUE by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from DSM to CUE?
The cheapest flights from DSM to CUE are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from DSM to CUE?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that'll take you from DSM to CUE. Sort your results by "Price (lowest to highest)" to snap up a great deal.
How many flights per day from Des Moines Intl. Airport (DSM) to Mariscal Lamar Airport (CUE)?
You'll have to catch a flight with a layover if you're traveling from Des Moines Intl. Airport (DSM) to Mariscal Lamar Airport (CUE). There are no daily direct flights on this route. However, simply filter your search to include one or more stops to discover an option that works for you.
What day of the week has the most flights from DSM to CUE?
Friday is generally the busiest day for flights, while Tuesday tends to be the quietest.* Just remember that flight schedules can vary depending on a number of factors, including the season and airline.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Des Moines Intl. Airport (DSM) to Mariscal Lamar Airport (CUE)?
To land at Mariscal Lamar Airport (CUE) on schedule, book a flight that leaves from Des Moines Intl. Airport (DSM) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Des Moines Intl. Airport (DSM) to Mariscal Lamar Airport (CUE) last-minute?
Waiting until just before your departure to book a flight from DSM to CUE often results in higher prices. While you might find some last-minute offers, there's no guarantee. Keep your travel plans flexible to boost your chances of getting a bargain.
Is it cheaper to book a DSM to CUE flight and hotel package?
You can save money by booking a DSM to CUE flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it's simple to manage it all in one place. Once you've selected your ideal accommodations and flights, consider adding extras including activities, car rentals and tours.
Can I cancel or change the date of my flight from Des Moines Intl. Airport (DSM) to Mariscal Lamar Airport (CUE)?
It's usually possible to reschedule or cancel your DSM to CUE flight. However, if it's been more than 24 hours since booking, additional fees may apply. Check your airline's policies in your itinerary to see what changes are allowed and whether any costs are involved. You'll also find more details on our Customer Service portal.

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*Available to One Key members.