$40 Cheap Flights from Medellín (MDE) to Cali (CLO)

View $40 flight on Sun, Nov 9, 2025Opens in a new window

Popular airlines from Jose Maria Cordova Intl. Airport (MDE) to Alfonso Bonilla Aragon Intl. Airport (CLO)

Cheap Flights from Medellín to Cali (MDE-CLO)

Prices were available within the past 7 days and start at $40 for one-way flights and $79 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Jetsmart SPA
Tue, Oct 28 - Sat, Nov 1
MDE
Medellin
CLO
Cali
$79 Roundtrip, found 3 days ago
$79
Roundtrip
found 3 days ago
Select Jetsmart SPA flight, departing Tue, Oct 28 from Medellin to Cali, returning Sat, Nov 1, priced at $79 found 3 days ago
Jetsmart SPA
Tue, Oct 21 - Wed, Oct 22
MDE
Medellin
CLO
Cali
$79 Roundtrip, just found
$79
Roundtrip
just found
Select Jetsmart SPA flight, departing Tue, Oct 21 from Medellin to Cali, returning Wed, Oct 22, priced at $79 just found
Jetsmart SPA
Thu, Oct 30 - Tue, Nov 4
MDE
Medellin
CLO
Cali
$82 Roundtrip, found 3 days ago
$82
Roundtrip
found 3 days ago
Select Jetsmart SPA flight, departing Thu, Oct 30 from Medellin to Cali, returning Tue, Nov 4, priced at $82 found 3 days ago
Jetsmart SPA
Wed, Oct 15 - Wed, Oct 22
MDE
Medellin
CLO
Cali
$84 Roundtrip, just found
$84
Roundtrip
just found
Select Jetsmart SPA flight, departing Wed, Oct 15 from Medellin to Cali, returning Wed, Oct 22, priced at $84 just found
Jetsmart SPA
Wed, Dec 17 - Wed, Dec 24
MDE
Medellin
CLO
Cali
$86 Roundtrip, found 2 days ago
$86
Roundtrip
found 2 days ago
Select Jetsmart SPA flight, departing Wed, Dec 17 from Medellin to Cali, returning Wed, Dec 24, priced at $86 found 2 days ago
Jetsmart SPA
Wed, Dec 17 - Wed, Dec 24
MDE
Medellin
CLO
Cali
$87 Roundtrip, found 2 days ago
$87
Roundtrip
found 2 days ago
Select Jetsmart SPA flight, departing Wed, Dec 17 from Medellin to Cali, returning Wed, Dec 24, priced at $87 found 2 days ago
Jetsmart SPA
Sat, Oct 18 - Sat, Oct 25
MDE
Medellin
CLO
Cali
$90 Roundtrip, just found
$90
Roundtrip
just found
Select Jetsmart SPA flight, departing Sat, Oct 18 from Medellin to Cali, returning Sat, Oct 25, priced at $90 just found
Jetsmart SPA
Sat, Dec 27 - Fri, Jan 16
MDE
Medellin
CLO
Cali
$91 Roundtrip, found 3 days ago
$91
Roundtrip
found 3 days ago
Select Jetsmart SPA flight, departing Sat, Dec 27 from Medellin to Cali, returning Fri, Jan 16, priced at $91 found 3 days ago
LATAM Airlines Group
Fri, Nov 14 - Tue, Nov 18
MDE
Medellin
CLO
Cali
$104 Roundtrip, found 5 days ago
$104
Roundtrip
found 5 days ago
Select LATAM Airlines Group flight, departing Fri, Nov 14 from Medellin to Cali, returning Tue, Nov 18, priced at $104 found 5 days ago
avianca
Wed, Dec 17 - Wed, Dec 24
MDE
Medellin
CLO
Cali
$165 Roundtrip, found 2 days ago
$165
Roundtrip
found 2 days ago
Select avianca flight, departing Wed, Dec 17 from Medellin to Cali, returning Wed, Dec 24, priced at $165 found 2 days ago

Find the cheapest month to fly from Medellín (MDE) to Cali (CLO)

May is typically the cheapest month to fly

From $60 - $153 per traveler.

Alternative airports near Cali

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Alfonso Bonilla Aragon Intl. CLO. Cheapest and Closest option available. Average driving time to city center is 27 minutes. Flights from $84
CLO
Alfonso Bonilla Aragon Intl.
CheapestClosest
Average driving time to city center27 min
Flights from $84
Flights from Medellín (MDE) to Cali (CLO)
Origin airport
José María Córdova Intl.
Destination airport
Alfonso Bonilla Aragon Intl.
Airlines serving
Jetsmart SPA, LATAM Airlines Group, avianca
Roundtrip price
$78
Distance
193 mi
Average flight time
1 hour 4 mins

Medellín to Cali Flights

The cheapest times to fly from Medellín to Cali

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Medellín to Cali are during the month of October. You can find some of the cheapest flights from Medellín to Cali with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Medellín to Cali

Sunday is one of the best days to book for cheap flights from Medellín to Cali: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Medellín to Cali

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Medellín to Cali in 2025. You can also book with separate airlines for your outbound and return journeys, from $40 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Medellín to Cali flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Medellín to Cali airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Jose Maria Cordova Intl. Airport (MDE) to Alfonso Bonilla Aragon Intl. Airport (CLO) cost?
Snag a cheap one-way flight from $40 or cheap return flight from $79 from Jose Maria Cordova Intl. Airport (MDE) to Alfonso Bonilla Aragon Intl. Airport (CLO) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Jose Maria Cordova Intl. Airport (MDE) to Alfonso Bonilla Aragon Intl. Airport (CLO)?
The cheapest month to fly from MDE to CLO is October, when demand is low. Off-peak season is typically when you'll find cheap fares for travel between these airports.
Which airlines fly direct from Jose Maria Cordova Intl. Airport (MDE) to Alfonso Bonilla Aragon Intl. Airport (CLO)?
Take the express route to Alfonso Bonilla Aragon Intl. Airport (CLO). 3 airlines operate direct routes from Jose Maria Cordova Intl. Airport (MDE), including:

  • AVIANCA
  • LATAM Airlines
  • JetSMART

What is the cheapest airline that flies from Jose Maria Cordova Intl. Airport (MDE) to Alfonso Bonilla Aragon Intl. Airport (CLO)?
JetSMART and LATAM Airlines are some popular airlines offering competitive fares. Don't forget that flight prices from Jose Maria Cordova Intl. Airport (MDE) to Alfonso Bonilla Aragon Intl. Airport (CLO) can change based on travel dates, demand and how early you book. With Expedia's filter tool, you can easily find a MDE to CLO flight that works with your plans and budget.
How many flights per day from Jose Maria Cordova Intl. Airport (MDE) to Alfonso Bonilla Aragon Intl. Airport (CLO)?
Each day on average, 6 nonstop flights operate from Jose Maria Cordova Intl. Airport (MDE) to Alfonso Bonilla Aragon Intl. Airport (CLO). Choose the departure date that best fits your schedule.
What are the most popular departure times for flights from Jose Maria Cordova Intl. Airport (MDE) to Alfonso Bonilla Aragon Intl. Airport (CLO)?
Flights between MDE and CLO are busiest at 5 PM. If you'd like a more relaxed atmosphere and potentially cheaper tickets, choose a departure that's outside typical rush times.
What day of the week has the most flights from MDE to CLO?
If you travel on a Sunday, you'll get the widest range of choices for flights from Jose Maria Cordova Intl. Airport (MDE) to Alfonso Bonilla Aragon Intl. Airport (CLO).
What is the earliest flight from Jose Maria Cordova Intl. Airport (MDE) to Alfonso Bonilla Aragon Intl. Airport (CLO)?
Jose Maria Cordova Intl. Airport (MDE)'s first flight to Alfonso Bonilla Aragon Intl. Airport (CLO) leaves at approximately 5:00AM UTC-5. With a total journey time of 1h 5m, you'll arrive at around 6:05AM UTC-5.
How long does it take to fly from Jose Maria Cordova Intl. Airport (MDE) to Alfonso Bonilla Aragon Intl. Airport (CLO)?
The average flight time from MDE to CLO is 1 hour and 3 minutes, covering a distance of 190 mi.
What airline has the least delays from MDE to CLO?
With 85% of flights generally landing on time, LATAM Airlines has the best on-time performance for direct flights from Jose Maria Cordova Intl. Airport (MDE) to Alfonso Bonilla Aragon Intl. Airport (CLO). To check your flight status and receive notifications if anything changes, head to the Expedia App.
What is the best time to fly from Jose Maria Cordova Intl. Airport (MDE) to Alfonso Bonilla Aragon Intl. Airport (CLO)?
To reach Alfonso Bonilla Aragon Intl. Airport (CLO) on schedule, choose a flight that leaves Jose Maria Cordova Intl. Airport (MDE) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for Cali from Jose Maria Cordova Intl. Airport (MDE)?
Alfonso Bonilla Aragon Intl. Airport (CLO) is the only airport in Cali with direct flights from Jose Maria Cordova Intl. Airport (MDE). Explore the options and find affordable fares on Expedia.
Is it cheaper to buy a plane ticket from Jose Maria Cordova Intl. Airport (MDE) to Alfonso Bonilla Aragon Intl. Airport (CLO) last-minute?
Booking your flight from MDE to CLO just before your journey is usually more expensive. However, if there's some wiggle room with your itinerary, you could grab a cheap last-minute fare.
Is it cheaper to book a MDE to CLO flight and hotel package?
Compared with arranging hotels and flights separately, booking a MDE to CLO flight and hotel package with Expedia could lead to significant savings. Better still, managing everything in one place will take the stress out of planning your trip. Just secure your flights and select from our wide range of hotels, then tailor your trip with extras like tours and car rentals.
Can I cancel or change the date of my flight from Jose Maria Cordova Intl. Airport (MDE) to Alfonso Bonilla Aragon Intl. Airport (CLO)?
In most instances, you can reschedule or cancel your MDE to CLO flight. However, additional charges may apply, especially if your booking was made over 24 hours ago. Check your itinerary for the airline's rules and fees on flight changes, or if you need further information, visit our Customer Service portal.

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*Available to One Key members.