$239 Cheap Flights from Santa Fe (SAF) to Greenville (GSP)

View $239 flight on Tue, Feb 10, 2026Opens in a new window

Popular airlines from Santa Fe Municipal Airport (SAF) to Greenville-Spartanburg Intl. Airport (GSP)

Cheap Flights from Santa Fe to Greenville (SAF-GSP)

Prices were available within the past 7 days and start at $239 for one-way flights and $359 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

United
Wed, Oct 22 - Wed, Oct 29
SAF
Santa Fe
GSP
Greenville
$359 Roundtrip, found 4 days ago
$359
Roundtrip
found 4 days ago
Select United flight, departing Wed, Oct 22 from Santa Fe to Greenville, returning Wed, Oct 29, priced at $359 found 4 days ago
United
Tue, Oct 21 - Wed, Oct 29
SAF
Santa Fe
GSP
Greenville
$379 Roundtrip, found 4 days ago
$379
Roundtrip
found 4 days ago
Select United flight, departing Tue, Oct 21 from Santa Fe to Greenville, returning Wed, Oct 29, priced at $379 found 4 days ago
American Airlines
Wed, Dec 17 - Fri, Jan 2
SAF
Santa Fe
GSP
Greenville
$403 Roundtrip, found 6 days ago
$403
Roundtrip
found 6 days ago
Select American Airlines flight, departing Wed, Dec 17 from Santa Fe to Greenville, returning Fri, Jan 2, priced at $403 found 6 days ago
American Airlines
Tue, Oct 14 - Tue, Oct 28
SAF
Santa Fe
GSP
Greenville
$416 Roundtrip, found 6 days ago
$416
Roundtrip
found 6 days ago
Select American Airlines flight, departing Tue, Oct 14 from Santa Fe to Greenville, returning Tue, Oct 28, priced at $416 found 6 days ago
American Airlines
Tue, Oct 21 - Sat, Oct 25
SAF
Santa Fe
GSP
Greenville
$435 Roundtrip, found 4 days ago
$435
Roundtrip
found 4 days ago
Select American Airlines flight, departing Tue, Oct 21 from Santa Fe to Greenville, returning Sat, Oct 25, priced at $435 found 4 days ago
American Airlines
Sat, Oct 18 - Fri, Oct 24
SAF
Santa Fe
GSP
Greenville
$440 Roundtrip, found 4 days ago
$440
Roundtrip
found 4 days ago
Select American Airlines flight, departing Sat, Oct 18 from Santa Fe to Greenville, returning Fri, Oct 24, priced at $440 found 4 days ago
American Airlines
Tue, Oct 21 - Tue, Oct 28
SAF
Santa Fe
GSP
Greenville
$445 Roundtrip, found 4 days ago
$445
Roundtrip
found 4 days ago
Select American Airlines flight, departing Tue, Oct 21 from Santa Fe to Greenville, returning Tue, Oct 28, priced at $445 found 4 days ago
American Airlines
Wed, Dec 17 - Fri, Jan 2
SAF
Santa Fe
GSP
Greenville
$453 Roundtrip, found 6 days ago
$453
Roundtrip
found 6 days ago
Select American Airlines flight, departing Wed, Dec 17 from Santa Fe to Greenville, returning Fri, Jan 2, priced at $453 found 6 days ago
American Airlines
Tue, Oct 14 - Tue, Oct 28
SAF
Santa Fe
GSP
Greenville
$456 Roundtrip, found 6 days ago
$456
Roundtrip
found 6 days ago
Select American Airlines flight, departing Tue, Oct 14 from Santa Fe to Greenville, returning Tue, Oct 28, priced at $456 found 6 days ago
American Airlines
Mon, Oct 20 - Sat, Oct 25
SAF
Santa Fe
GSP
Greenville
$459 Roundtrip, found 4 days ago
$459
Roundtrip
found 4 days ago
Select American Airlines flight, departing Mon, Oct 20 from Santa Fe to Greenville, returning Sat, Oct 25, priced at $459 found 4 days ago

Alternative airports near Greenville

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Greenville-Spartanburg Intl. GSP. Cheapest option available. Average driving time to city center is 18 minutes. Flights from $416
GSP
Greenville-Spartanburg Intl.
Cheapest
Average driving time to city center18 min
Flights from $416

Frequently asked questions

How much does a flight from Santa Fe Municipal Airport (SAF) to Greenville-Spartanburg Intl. Airport (GSP) cost?
Lock in a cheap one-way flight from $239 or cheap return flight from $359 from Santa Fe Municipal Airport (SAF) to Greenville-Spartanburg Intl. Airport (GSP) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Santa Fe Municipal Airport (SAF) to Greenville-Spartanburg Intl. Airport (GSP)?
The cheapest month to fly from SAF to GSP is October, when there's less demand. Off-peak season is often when airlines offer better prices between these airports.
What is the cheapest airline that flies from Santa Fe Municipal Airport (SAF) to Greenville-Spartanburg Intl. Airport (GSP)?
Use the filters on Expedia to compare different airlines and find the cheapest carrier that'll fly you from SAF to GSP. Then, sort your results by "Price (lowest to highest)" to snag a great deal.
How many flights per day from Santa Fe Municipal Airport (SAF) to Greenville-Spartanburg Intl. Airport (GSP)?
Direct flights from Santa Fe Municipal Airport (SAF) to Greenville-Spartanburg Intl. Airport (GSP) aren't available daily, so you'll need to take a flight with a layover. Explore your options with our filter tool. Enter your travel dates and choose either "1 Stop" or "2+ Stops."
What day of the week has the most flights from SAF to GSP?
Friday is usually the busiest day for flights, while Tuesday tends to be the quietest.* Remember that flight schedules can change based on a number of factors, including the time of year and carrier.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Santa Fe Municipal Airport (SAF) to Greenville-Spartanburg Intl. Airport (GSP)?
Book a flight from Santa Fe Municipal Airport (SAF) to Greenville-Spartanburg Intl. Airport (GSP) that leaves before 3 PM to reduce the likelihood of delays and cancellations. Departures after this time have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Santa Fe Municipal Airport (SAF) to Greenville-Spartanburg Intl. Airport (GSP) last-minute?
Holding off until just before your trip to book a ticket from SAF to GSP often results in higher prices. While it's possible to find some last-minute discounts, they aren't always guaranteed. Keep your travel schedule open for the best chance of scoring a bargain.
Is it cheaper to book a SAF to GSP flight and hotel package?
Compared with arranging flights and hotels separately, booking a SAF to GSP flight and hotel package with Expedia could result in significant savings. Better still, having everything in one convenient place will take the hassle out of planning your trip. Just pick your flights and select from our wide range of stays, then customize your trip with other add-ons like tours, car rentals and activities.
Can I cancel or change the date of my flight from Santa Fe Municipal Airport (SAF) to Greenville-Spartanburg Intl. Airport (GSP)?
In most cases, you can modify or cancel your SAF to GSP flight. However, additional fees may apply, especially if you made your booking more than 24 hours ago. Double-check your itinerary for the airline's fees and policies on flight changes, or if you'd like further information, go to our Customer Service portal.

Travel information

Travel information

Origin airport
Santa Fe Municipal
Destination airport
Greenville-Spartanburg Intl.
Airlines serving
American Airlines, United
Roundtrip price
$359
Distance
1344 mi

Book with confidence

Book with confidence

Santa Fe to Greenville Flights

The cheapest times to fly from Santa Fe to Greenville

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Santa Fe to Greenville are during the month of October. You can find some of the cheapest flights from Santa Fe to Greenville with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Santa Fe to Greenville

Sunday is one of the best days to book for cheap flights from Santa Fe to Greenville: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Santa Fe to Greenville

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Santa Fe to Greenville in 2025. You can also book with separate airlines for your outbound and return journeys, from $239 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Santa Fe to Greenville flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Santa Fe to Greenville airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Santa Fe to Greenville Flights

Explore a world of travel with Expedia

Explore a world of travel with Expedia

*Available to One Key members.