$233 Cheap Flights from Columbia (COU) to Greenville (GSP)

View $233 flight on Thu, Dec 25, 2025Opens in a new window

Popular airlines from Columbia, MO (COU-Columbia Regional) to Greenville-Spartanburg Intl. Airport (GSP)

Cheap Flights from Columbia to Greenville (COU-GSP)

Prices were available within the past 7 days and start at $233 for one-way flights and $270 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

United
Tue, Apr 28 - Thu, May 7
COU
Columbia
GSP
Greenville
$270 Roundtrip, found 5 days ago
$270
Roundtrip
found 5 days ago
Select United flight, departing Tue, Apr 28 from Columbia to Greenville, returning Thu, May 7, priced at $270 found 5 days ago
United
Tue, Apr 28 - Tue, May 5
COU
Columbia
GSP
Greenville
$308 Roundtrip, found 5 days ago
$308
Roundtrip
found 5 days ago
Select United flight, departing Tue, Apr 28 from Columbia to Greenville, returning Tue, May 5, priced at $308 found 5 days ago
United
Mon, Nov 10 - Tue, Nov 18
COU
Columbia
GSP
Greenville
$313 Roundtrip, found 6 days ago
$313
Roundtrip
found 6 days ago
Select United flight, departing Mon, Nov 10 from Columbia to Greenville, returning Tue, Nov 18, priced at $313 found 6 days ago
United
Mon, Nov 10 - Sat, Nov 15
COU
Columbia
GSP
Greenville
$318 Roundtrip, found 6 days ago
$318
Roundtrip
found 6 days ago
Select United flight, departing Mon, Nov 10 from Columbia to Greenville, returning Sat, Nov 15, priced at $318 found 6 days ago
United
Tue, Apr 28 - Thu, May 7
COU
Columbia
GSP
Greenville
$320 Roundtrip, found 5 days ago
$320
Roundtrip
found 5 days ago
Select United flight, departing Tue, Apr 28 from Columbia to Greenville, returning Thu, May 7, priced at $320 found 5 days ago
United
Wed, Nov 12 - Sat, Nov 15
COU
Columbia
GSP
Greenville
$324 Roundtrip, found 6 days ago
$324
Roundtrip
found 6 days ago
Select United flight, departing Wed, Nov 12 from Columbia to Greenville, returning Sat, Nov 15, priced at $324 found 6 days ago
United
Mon, Nov 10 - Mon, Nov 17
COU
Columbia
GSP
Greenville
$336 Roundtrip, found 6 days ago
$336
Roundtrip
found 6 days ago
Select United flight, departing Mon, Nov 10 from Columbia to Greenville, returning Mon, Nov 17, priced at $336 found 6 days ago
United
Tue, Apr 28 - Thu, May 7
COU
Columbia
GSP
Greenville
$340 Roundtrip, found 5 days ago
$340
Roundtrip
found 5 days ago
Select United flight, departing Tue, Apr 28 from Columbia to Greenville, returning Thu, May 7, priced at $340 found 5 days ago
United
Mon, Nov 10 - Mon, Nov 17
COU
Columbia
GSP
Greenville
$340 Roundtrip, found 6 days ago
$340
Roundtrip
found 6 days ago
Select United flight, departing Mon, Nov 10 from Columbia to Greenville, returning Mon, Nov 17, priced at $340 found 6 days ago
American Airlines
Thu, Dec 4 - Sun, Dec 7
COU
Columbia
GSP
Greenville
$402 Roundtrip, found 15 hours ago
$402
Roundtrip
found 15 hours ago
Select American Airlines flight, departing Thu, Dec 4 from Columbia to Greenville, returning Sun, Dec 7, priced at $402 found 15 hours ago

Frequently asked questions

How much does a flight from Columbia Regional Airport (COU) to Greenville-Spartanburg Intl. Airport (GSP) cost?
Grab a cheap one-way flight from $233 or cheap return flight from $270 from Columbia Regional Airport (COU) to Greenville-Spartanburg Intl. Airport (GSP) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Columbia Regional Airport (COU) to Greenville-Spartanburg Intl. Airport (GSP)?
The cheapest month to fly from COU to GSP is April, when demand is low. Off-peak season is usually when airlines offer lower prices between these airports.
What is the cheapest airline that flies from Columbia Regional Airport (COU) to Greenville-Spartanburg Intl. Airport (GSP)?
Use the filters on Expedia to compare airlines and find the most affordable carrier that'll fly you from COU to GSP. Then, sort your results by "Price (lowest to highest)" to score a good deal.
How many flights per day from Columbia Regional Airport (COU) to Greenville-Spartanburg Intl. Airport (GSP)?
There aren't any daily direct flights available from Columbia Regional Airport (COU) to Greenville-Spartanburg Intl. Airport (GSP). But you can book flights with layovers. Filter your search results on Expedia to include one or two stops, and you'll be cruising above the clouds before you know it.
What day of the week has the most flights from COU to GSP?
Friday is generally the busiest day for flights, while Tuesday is often the quietest.* Just remember that flight schedules can change depending on a range of factors, such as the carrier and season.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Columbia Regional Airport (COU) to Greenville-Spartanburg Intl. Airport (GSP)?
Select a flight from Columbia Regional Airport (COU) to Greenville-Spartanburg Intl. Airport (GSP) that leaves before 3 PM to reduce the likelihood of delays and cancellations. Departures after this hour have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Columbia Regional Airport (COU) to Greenville-Spartanburg Intl. Airport (GSP) last-minute?
Last-minute bookings from COU to GSP are usually more expensive. For the cheapest rates, start searching for flights as early as possible. That being said, if you're flexible with your travel plans, it's possible to land a cheap ticket right before you leave.
Is it cheaper to book a COU to GSP flight and hotel package?
Compared with arranging hotels and flights separately, booking a COU to GSP flight and hotel package with Expedia could result in significant savings. What's more, having everything in one easy place will take the stress out of travel planning. Simply pick your flights and choose from our wide range of stays, then personalize your trip with other add-ons like activities, tours and car rentals.
Can I cancel or change the date of my flight from Columbia Regional Airport (COU) to Greenville-Spartanburg Intl. Airport (GSP)?
If you reserved your COU to GSP flight in the last 24 hours, you may be able to cancel or modify it without fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal for further details.

Travel information

Origin airport
Columbia Regional
Destination airport
Greenville-Spartanburg Intl.
Airlines serving
American Airlines, United
Roundtrip price
$269
Distance
615 mi

Book with confidence

Columbia to Greenville Flights

The cheapest times to fly from Columbia to Greenville

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Columbia to Greenville are during the month of April. You can find some of the cheapest flights from Columbia to Greenville with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Columbia to Greenville

Sunday is one of the best days to book for cheap flights from Columbia to Greenville: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Columbia to Greenville

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Columbia to Greenville in 2025. You can also book with separate airlines for your outbound and return journeys, from $233 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Columbia to Greenville flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Columbia to Greenville airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Columbia to Greenville Flights

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*Available to One Key members.