Florence Vacation Rentals

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Check prices for these dates

In two weeks
Feb 13 - Feb 15
In two months
Mar 27 - Mar 29
In three months
Apr 24 - Apr 26
In four months
May 22 - May 24

Our top choices for Florence vacation rentals

Microwave, oven, stovetop, dishwasher

Apartment in Hartsville

Charming 2-bedroom apartment MINUTES from Darlington Raceway with pond views
10.0 out of 10, Exceptional, (8 reviews)
"Sooo good. Peaceful country setting yet close to everything. We will definitely try staying here again next time."
United States
Randy W.
$142 nightly
The price is $155
Feb 1 - Feb 2
Total with taxes and fees
Charming 2-bedroom apartment MINUTES from Darlington Raceway with pond views
1 bedroom, iron/ironing board, travel crib, free WiFi

Cottage in Sellers

Charming Cottage with easy access to local attractions-pet and kid friendly
9.4 out of 10, Exceptional, (20 reviews)
"So charming. The hostess is very accommodating and willing. We felt very welcome. All the accoutrements are tasteful. We had plenty of what we needed for our little celebration. Not too far of a skirt to Flo-town for a bite and some dessert. "
United States
Benjamin
$182 nightly
The price is $198
Feb 1 - Feb 2
Total with taxes and fees
Charming Cottage with easy access to local attractions-pet and kid friendly
TV

Cottage in Hartsville

Cozy Blue Cottage 2BR/1BA
9.0 out of 10, Wonderful, (8 reviews)
"Enjoyed my time in Hartsville with family "
United States
Lori
$208 nightly
The price is $233
Jan 27 - Jan 28
Total with taxes and fees
Cozy Blue Cottage 2BR/1BA
1 bedroom, free WiFi, bed sheets

Apartment in Mullins

imperial motel
$118 nightly
The price is $128
Jan 27 - Jan 28
Total with taxes and fees
imperial motel
2 bedrooms, WiFi, bed sheets

Mobile Home in Hartsville

Lakeside 2-bedroom RV in charming Hartsville with AC, WiFi
8.0 out of 10, Very Good, (1 review)
"The stay was fine , with no problems."
United States
Mark H.
$138 nightly
The price is $150
Feb 1 - Feb 2
Total with taxes and fees
Lakeside 2-bedroom RV in charming Hartsville with AC, WiFi
Dining

Vacation Home in Florence

Charming 3-bedroom, 2.5 bath townhome. Largest with accommodations in Florence.
9.0 out of 10, Wonderful, (2 reviews)
"Beautiful home and had all the amenities just like home. It was my home away from home."
United States
Yvette M.
$416 nightly
The price is $466
Jan 27 - Jan 28
Total with taxes and fees
Charming 3-bedroom, 2.5 bath townhome. Largest with accommodations in Florence.
Interior

Vacation Home in Florence

Walking distance from one of South Carolina's top Medical centers.
9.8 out of 10, Exceptional, (42 reviews)
"The house was beautiful. We would stay there again!!"
United States
Stephanie L.
$204 nightly
The price is $229
Jan 29 - Jan 30
Total with taxes and fees
Walking distance from one of South Carolina's top Medical centers.
Outdoor pool

Vacation Home in Mullins

Private Pool house in Mullins
9.2 out of 10, Wonderful, (7 reviews)
"Great stay in Mullins. We enjoyed family time at the pool and had everything we needed. "
United States
Carla H.
$167 nightly
The price is $182
Jan 29 - Jan 30
Total with taxes and fees
Private Pool house in Mullins
Smart TV, books

Vacation Home in Mullins

Peaceful Farm Getaway
10.0 out of 10, Exceptional, (32 reviews)
"Excellent Space. Loved It."
United States
Rodney
$194 nightly
The price is $211
Jan 27 - Jan 28
Total with taxes and fees
Peaceful Farm Getaway
Exterior

Vacation Home in Society Hill

In 1840 Burn Cottage
9.6 out of 10, Exceptional, (34 reviews)
"Nice historic house provided authentic late-1800s three night stay. Enjoyed our stay."
United States
Ansel C.
$191 nightly
The price is $208
Jan 28 - Jan 29
Total with taxes and fees
In 1840 Burn Cottage
Fridge, microwave, oven, stovetop

Mobile Home in Latta

The Pinecone Retreat - Only 1 mile from i95
$124 nightly
The price is $135
Jan 27 - Jan 28
Total with taxes and fees
The Pinecone Retreat - Only 1 mile from i95
Interior

Cabin in Marion

Secret SC Cabin on 100 acres Hot Tub Large Pond
9.6 out of 10, Exceptional, (180 reviews)
"Our stay at Rodney’s cabin was just what we needed... Some time alone on 100 acres. Other than the peaceful sound of the waterfall trickling to the pond, Mother Nature and animals can only be heard. The cabin is equipped with everything you need to enjoy your stay as you reconnect with one another and the great outdoors. Bring whatever flavors you like and learn to cook together on a Big Green Egg that Rodney has built into his outdoor kitchen!! We relaxed in the hot tub each night and can’t...
United States
michael l.
$432 nightly
The price is $470
Jan 27 - Jan 28
Total with taxes and fees
Secret SC Cabin on 100 acres Hot Tub Large Pond
Interior

Apartment in Marion

Lovely upscale 3-bedroom Loft apartment downtown Marion
$202 nightly
The price is $220
Jan 27 - Jan 28
Total with taxes and fees
Lovely upscale 3-bedroom Loft apartment downtown Marion
Interior

Vacation Home in Florence

Perfect Stop • Near I-95, Downtown & Civic Center and Darlington
9.6 out of 10, Exceptional, (4 reviews)
"It was perfect! And the host was the best everrrr I loved every second I will be returning! "
United States
Kimesha C.
$243 nightly
The price is $272
Jan 27 - Jan 28
Total with taxes and fees
Perfect Stop • Near I-95, Downtown & Civic Center and Darlington
Dining

Vacation Home in Marion

Located in Marion. Only 1 hour from Myrtle Beach, 35 minutes from Florence!
9.0 out of 10, Wonderful, (6 reviews)
"It was a great place. "
United States
Cindy N.
$549 nightly
The price is $598
Jan 27 - Jan 28
Total with taxes and fees
Located in Marion. Only 1 hour from Myrtle Beach, 35 minutes from Florence!
Interior

Vacation Home in Florence

Take a rest in Florence .Ideal for i95 traveler and Florence Center and Buc-ee's
10.0 out of 10, Exceptional, (40 reviews)
"I would definitely stay again! Great location."
United States
LaDara D.
$229 nightly
The price is $257
Jan 28 - Jan 29
Total with taxes and fees
Take a rest in Florence .Ideal for i95 traveler and Florence Center and Buc-ee's
Fridge, microwave, oven, stovetop

Vacation Home in Camden

Camden Cottage
10.0 out of 10, Exceptional, (56 reviews)
"Charming cottage on a beautiful property, super dog friendly and the owner is absolutely fantastic about responding to any questions or concerns, 100% would recommend and would stay again!!! "
United States
Paul H.
$159 nightly
The price is $178
Feb 4 - Feb 5
Total with taxes and fees
Camden Cottage
WiFi, bed sheets

Apartment in Camden

Historic Camden Showstopper!! THE LITTLE GARDNER’S COTTAGE
$138 nightly
The price is $155
Feb 9 - Feb 10
Total with taxes and fees
Historic Camden Showstopper!! THE LITTLE GARDNER’S COTTAGE
Smart TV, books

Vacation Home in Pembroke

Charming 2-bedroom house with AC, WiFi in the heart of Pembroke
9.8 out of 10, Exceptional, (6 reviews)
"Great place and comfortable , perfect for my needs . my only complaint was this area has alot of noisy train traffic at all hrs. of the night."
United States
Rick T.
$341 nightly
The price is $385
Jan 27 - Jan 28
Total with taxes and fees
Charming 2-bedroom house with AC, WiFi in the heart of Pembroke
Fridge, microwave, oven, stovetop

Vacation Home in Rembert

Pear Tree Farm. Peaceful, Country living at its best. 12 stables. Pet Friendly
9.6 out of 10, Exceptional, (24 reviews)
"Would definitely stay here again! This property is very reasonably priced. Host was great in communication. It was just a lovely, peaceful, and safe place to stay! Wish we would have stayed longer! Thank you so very much."
United States
Josh M.
$221 nightly
The price is $247
Jan 27 - Jan 28
Total with taxes and fees
Pear Tree Farm. Peaceful, Country living at its best. 12 stables. Pet Friendly
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Florence Hotel Reviews

Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

10/10 Excellent
"Nice clean room. Staff was very friendly."
Charles 1-night trip
Posted 2 days ago
Howard Johnson by Wyndham Florence

Find out more about Florence

Everything you need to know about Florence vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Florence vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Florence vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Florence vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Florence. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Florence in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $198 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Florence rentals

At Expedia, we put the best Florence vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Florence rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Florence vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Florence. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Explore a world of travel with Expedia

Frequently asked questions

Can I find vacation rentals in Florence?

Yes, we have vacation rentals in Florence close to Eastern Carolina Agricultural Fairgrounds, or you can choose a secluded option if you'd like a relaxing place to stay. Tourists like the array of shops and top-notch restaurants in Florence. You can also check out the entertainment venues while you're visiting.

What are some of the best vacation rentals in Florence?

Walking distance from one of South Carolina's top Medical centers.: Visitors give good reviews to this Florence vacation home rental, which offers a garden, a selection of games, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Other favorite homes for rent in Florence are Perfect Get-Away In The Heart Of Downtown Florence and Charming and Cozy 4BR 2BA House with Parking, Minutes from I-95 and Buc-ees.

How many vacation rentals will I find in Florence?

Choose from 36 Expedia vacation rentals in Florence for a memorable vacation.

What can I see and do in Florence?

Florence Veterans Park and Palmetto Shores Lake are a couple of scenic spots to enjoy the outdoors, whereas Florence Museum is one of the cultural attractions. Other places in town to visit include Dr. Eddie Floyd Tennis Center and Magnolia Mall.

What are vacation rentals like in Florence?

Vacation rentals are privately owned accommodations you can reserve for a couple days or more in Florence. Vacation rentals offer extras such as hot tubs, fire pits, and patios so you'll have a home away from home. If you're concerned about cleanliness, a vacation rental can provide a sense of privacy away from public hotel elevators and busy concierge desks while still allowing you to travel. You'll also get more space in a vacation rental than in a traditional hotel, which is another reason why a vacation rental is a popular choice for a family trip or a small group gathering.