Title: TOP 10 Hotels in Florence, SC (from $67) - COMPETITIVE PRICES | Expedia.com [Florence Travel Guide](https://expedia.com/Florence.dx1221)[Vacation Rentals in Florence](https://expedia.com/Florence-Vacation-Rentals.d1221.Travel-Guide-VacationRentals)[Flights to Florence](https://expedia.com/Cheap-Flights-To-Florence.d1221.Travel-Guide-Flights)[Things to do in Florence](https://expedia.com/Things-To-Do-In-Florence.d1221.Travel-Guide-Activities)[Car Rentals in Florence](https://expedia.com/Car-Rentals-In-Florence.d1221.Car-Rental-Guide)[Florence Vacation Packages](https://expedia.com/Florence.d1221.Destination-Travel-Guides) ![Lodging Image](https://a.travel-assets.com/travel-assets-manager/bex-affinities/lodging.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/bex-affinities/lodging.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Florence Pet friendly [](https://www.expedia.com/Hotel-Search?destination=Florence%2C+South+Carolina%2C+United+States+of+America®ionId=1221&latLong=34.197201%2C-79.768181&adults=2&startDate=2026-04-12&d1=2026-04-12&endDate=2026-04-14&d2=2026-04-14&amenities=PETS) Pool [](https://www.expedia.com/Hotel-Search?destination=Florence%2C+South+Carolina%2C+United+States+of+America®ionId=1221&latLong=34.197201%2C-79.768181&adults=2&startDate=2026-04-12&d1=2026-04-12&endDate=2026-04-14&d2=2026-04-14&amenities=POOL) Family friendly [](https://www.expedia.com/Hotel-Search?destination=Florence%2C+South+Carolina%2C+United+States+of+America®ionId=1221&latLong=34.197201%2C-79.768181&adults=2&startDate=2026-04-12&d1=2026-04-12&endDate=2026-04-14&d2=2026-04-14&travelerType=family_friendly) Hot tub [](https://www.expedia.com/Hotel-Search?destination=Florence%2C+South+Carolina%2C+United+States+of+America®ionId=1221&latLong=34.197201%2C-79.768181&adults=2&startDate=2026-04-12&d1=2026-04-12&endDate=2026-04-14&d2=2026-04-14&amenities=HOT_TUB) Cottage [](https://www.expedia.com/Hotel-Search?destination=Florence%2C+South+Carolina%2C+United+States+of+America®ionId=1221&latLong=34.197201%2C-79.768181&adults=2&startDate=2026-04-12&d1=2026-04-12&endDate=2026-04-14&d2=2026-04-14&lodging=COTTAGE) Apart­ment [](https://www.expedia.com/Hotel-Search?destination=Florence%2C+South+Carolina%2C+United+States+of+America®ionId=1221&latLong=34.197201%2C-79.768181&adults=2&startDate=2026-04-12&d1=2026-04-12&endDate=2026-04-14&d2=2026-04-14&lodging=APARTMENT) Condo [](https://www.expedia.com/Hotel-Search?destination=Florence%2C+South+Carolina%2C+United+States+of+America®ionId=1221&latLong=34.197201%2C-79.768181&adults=2&startDate=2026-04-12&d1=2026-04-12&endDate=2026-04-14&d2=2026-04-14&lodging=CONDO) ## Check prices for these dates Tonight [Mar 29 - Mar 30](https://www.expedia.com/Hotel-Search?regionId=1221&startDate=2026-03-29&endDate=2026-03-30&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 30 - Mar 31](https://www.expedia.com/Hotel-Search?regionId=1221&startDate=2026-03-30&endDate=2026-03-31&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Apr 3 - Apr 5](https://www.expedia.com/Hotel-Search?regionId=1221&startDate=2026-04-03&endDate=2026-04-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Apr 10 - Apr 12](https://www.expedia.com/Hotel-Search?regionId=1221&startDate=2026-04-10&endDate=2026-04-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Florence hotels ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/32fd6fc1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds, Non Smoking | 1 bedroom, desk, blackout drapes, soundproofing](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/8a1b879d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee service](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/e7174d53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/7b1066c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Howard Johnson by Wyndham Florence [](https://www.expedia.com/Florence-Hotels-Howard-Johnson-By-Wyndham-Florence.h11037.Hotel-Information) Florence 8.6/10 Excellent (2,604 reviews) "Very comfortable room and the hotel was close to the Interstate and many good trestaurants." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Charles $60 nightly $68 total Apr 26 - Apr 27 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Howard-Johnson-By-Wyndham-Florence.h11037.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/e4f3361f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/96d5feb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/0b9239a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/00586c85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Park Inn by Radisson Florence, SC [](https://www.expedia.com/Florence-Hotels-Park-Inn-By-Radisson-Florence.h47086732.Hotel-Information) Florence 9.0/10 Wonderful (2,234 reviews) "Bed was comfortable and breakfast was good " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Bernard $89 nightly $100 total Apr 26 - Apr 27 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Park-Inn-By-Radisson-Florence.h47086732.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/970000/970000/969975/ffaddd2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/970000/970000/969975/bdf580c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/970000/970000/969975/9f09eded.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/970000/970000/969975/689a1cfa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG [](https://www.expedia.com/Florence-Hotels-Holiday-Inn-Express-Hotel-Suites-Florence-I-95-At-Hwy-327.h969975.Hotel-Information) Florence 8.6/10 Excellent (1,000 reviews) "The stay was great" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dianne $131 nightly $147 total Apr 12 - Apr 13 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Holiday-Inn-Express-Hotel-Suites-Florence-I-95-At-Hwy-327.h969975.Hotel-Information) ![Suite, 1 King Bed with Sofa bed, Non Smoking | Premium bedding, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/6f5032ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/dca04534.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/4e5e1bcd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/3cf3d3ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn & Suites Florence Civic Center [](https://www.expedia.com/Florence-Hotels-Quality-Inn-And-Suites-Civic.h11535.Hotel-Information) Florence 8.4/10 Very Good (40 reviews) "Clean, quiet and safe location to spend the night. " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) David $93 nightly $104 total Mar 30 - Mar 31 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Quality-Inn-And-Suites-Civic.h11535.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/64840011.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/fefdad76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillowtop beds, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/6df606aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Queen Beds, Non Smoking | Pillowtop beds, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/a63ff680.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Florence Center Area [](https://www.expedia.com/Florence-Hotels-Comfort-Inn-Suites.h38336321.Hotel-Information) Florence 9.0/10 Wonderful (1,242 reviews) "Clean room, good breakfast...very nice overnight stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gerry $101 nightly $114 total Apr 26 - Apr 27 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Comfort-Inn-Suites.h38336321.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/3000000/2400000/2393000/2392993/995e3ecd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/3000000/2400000/2393000/2392993/59604fe9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business center](https://images.trvl-media.com/lodging/3000000/2400000/2393000/2392993/3e9ccd76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2400000/2393000/2392993/36a85f8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Florence-North-I-95 [](https://www.expedia.com/Florence-Hotels-Hampton-Inn-Suites-Florence-North-I-95.h2392993.Hotel-Information) Florence 9.0/10 Wonderful (881 reviews) "Busy hotel. Nice rooms awesome free breakfast " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ken $110 nightly $123 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Hampton-Inn-Suites-Florence-North-I-95.h2392993.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/18000000/17040000/17036000/17035960/5dc20640.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/18000000/17040000/17036000/17035960/5a5d3612.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/18000000/17040000/17036000/17035960/6cda2c89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/18000000/17040000/17036000/17035960/86912dec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Florence I-20 [](https://www.expedia.com/Florence-Hotels-Fairfield-Inn-Suites-By-Marriott-Florence-I-20.h17035960.Hotel-Information) Florence 9.2/10 Wonderful (606 reviews) "Great place to stay while we have long trip from FL to NY" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sergii $114 nightly $128 total Apr 6 - Apr 7 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Fairfield-Inn-Suites-By-Marriott-Florence-I-20.h17035960.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/77000000/76030000/76026200/76026194/da6adbe4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/77000000/76030000/76026200/76026194/831257e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/77000000/76030000/76026200/76026194/e765049f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/77000000/76030000/76026200/76026194/0724af0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aloft Florence [](https://www.expedia.com/Florence-Hotels-Aloft-Florence.h76026194.Hotel-Information) Florence 8.6/10 Excellent (301 reviews) "Parking is great " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) cheto $111 nightly $124 total Apr 19 - Apr 20 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Aloft-Florence.h76026194.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1210000/1202800/1202776/778f48dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/2000000/1210000/1202800/1202776/25ba1b1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/2000000/1210000/1202800/1202776/8b979844.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1210000/1202800/1202776/0da1bc1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Executive Inn [](https://www.expedia.com/Florence-Hotels-Best-Western-Executive-Inn.h1202776.Hotel-Information) Latta 8.2/10 Very Good (974 reviews) "The staff at check in and the staff at check out was wonderful " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jackieann $106 nightly $116 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Best-Western-Executive-Inn.h1202776.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/80000/74500/74404/7f29240e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking | Premium bedding, desk, soundproofing, iron/ironing board](https://images.trvl-media.com/lodging/1000000/80000/74500/74404/f732d5e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/80000/74500/74404/3c3cf86e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/80000/74500/74404/867e6dd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Florence [](https://www.expedia.com/Florence-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Florence.h74404.Hotel-Information) Florence 7.8/10 Good (1,637 reviews) "Good hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Eric $104 nightly $117 total Apr 22 - Apr 23 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Florence.h74404.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/33000000/32780000/32772900/32772870/c8bc9166.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/33000000/32780000/32772900/32772870/0e00b7af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/33000000/32780000/32772900/32772870/c29c3321.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Serves lunch and dinner](https://images.trvl-media.com/lodging/33000000/32780000/32772900/32772870/e2ea309a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Place Florence Downtown [](https://www.expedia.com/Florence-Hotels-Hyatt-Place-Florence-Downtown.h32772870.Hotel-Information) Florence 9.0/10 Wonderful (1,004 reviews) "It was a beautiful room and breakfast was great. Staff was wonderful " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stephanie $122 nightly $137 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Hyatt-Place-Florence-Downtown.h32772870.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/28000000/27050000/27041900/27041849/a8854f5d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/28000000/27050000/27041900/27041849/8339db76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/28000000/27050000/27041900/27041849/5b7b6acc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/28000000/27050000/27041900/27041849/20f68e84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru by Hilton Florence I-95 [](https://www.expedia.com/Florence-Hotels-Tru-By-Hilton-Florence-I-95.h27041849.Hotel-Information) Florence 8.4/10 Very Good (1,002 reviews) "Nice clean simple hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) ROBIN $101 nightly $113 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Tru-By-Hilton-Florence-I-95.h27041849.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/59000000/58990000/58985600/58985556/2544034c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/59000000/58990000/58985600/58985556/5cc0357e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast](https://images.trvl-media.com/lodging/59000000/58990000/58985600/58985556/fcf4fdd5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/59000000/58990000/58985600/58985556/2a6d6c86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Latta by IHG [](https://www.expedia.com/Florence-Hotels-Holiday-Inn-Express-Suites-Latta.h58985556.Hotel-Information) Latta 9.6/10 Exceptional (568 reviews) "Great visit to this site...convenient to food, gas, and the staff was so pleasant. Breakfast was very good and I would not hesitate to stay there again" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cheryl $118 nightly $129 total Apr 6 - Apr 7 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Holiday-Inn-Express-Suites-Latta.h58985556.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/90000/84600/84519/a3469465.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed with Sofa bed | Desk, iron/ironing board, free cribs/infant beds, free rollaway beds](https://images.trvl-media.com/lodging/1000000/90000/84600/84519/w4000h2663x0y0-4c6e3b9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast and dinner served](https://images.trvl-media.com/lodging/1000000/90000/84600/84519/4eb73ad9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/90000/84600/84519/a86309c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott Florence [](https://www.expedia.com/Florence-Hotels-Courtyard-By-Marriott-Florence.h84519.Hotel-Information) Florence 7.8/10 Good (718 reviews) "Very welcoming and professionally staff hotel. Will definitely come back " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alina $101 nightly $113 total Apr 26 - Apr 27 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Courtyard-By-Marriott-Florence.h84519.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/4000000/3030000/3026100/3026100/c68ab7f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/4000000/3030000/3026100/3026100/5054dc3e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/4000000/3030000/3026100/3026100/d963a865.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, pillowtop beds, desk, blackout drapes](https://images.trvl-media.com/lodging/4000000/3030000/3026100/3026100/67a43c3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites Florence I-95 [](https://www.expedia.com/Florence-Hotels-Comfort-Suites-Florence-I-95.h3026100.Hotel-Information) Florence 8.4/10 Very Good (1,004 reviews) "Everything was great" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brad $104 nightly $116 total Apr 19 - Apr 20 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Comfort-Suites-Florence-I-95.h3026100.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/1000000/50000/42900/42876/88f4ba4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/50000/42900/42876/e1b59003.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/42900/42876/1e0c4eb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/50000/42900/42876/f287bfc0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Florence Center [](https://www.expedia.com/Florence-Hotels-Hampton-Inn-Suites-Florence-Center.h42876.Hotel-Information) Florence 9.0/10 Wonderful (863 reviews) "Parking convenient. Room clean and bed very comfortable. Would recommend and plan to stay again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) MG $110 nightly $123 total Apr 26 - Apr 27 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Hampton-Inn-Suites-Florence-Center.h42876.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/210000/202900/202854/1397c485.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds | In-room safe, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/210000/202900/202854/f91ba6cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/210000/202900/202854/a58ac844.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/210000/202900/202854/bbb1ae5f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn by Marriott Hartsville [](https://www.expedia.com/Florence-Hotels-Fairfield-Inn-By-Marriott-Hartsville.h202854.Hotel-Information) Hartsville 8.6/10 Excellent (714 reviews) "Everything was excellent--staff, room, bed, parking, cleanliness!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kimberly $88 nightly $99 total Apr 3 - Apr 4 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Fairfield-Inn-By-Marriott-Hartsville.h202854.Hotel-Information) ![Free buffet breakfast](https://images.trvl-media.com/lodging/1000000/10000/2100/2009/14fbad71.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, rollaway beds, free WiFi](https://images.trvl-media.com/lodging/1000000/10000/2100/2009/7bc17024.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed with Sofa bed, Non Smoking | Desk, iron/ironing board, rollaway beds, free WiFi](https://images.trvl-media.com/lodging/1000000/10000/2100/2009/9dd323a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/2100/2009/7156b13a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Dillon [](https://www.expedia.com/Florence-Hotels-Quality-Inn-Suites.h2009.Hotel-Information) Dillon 7.2/10 Good (788 reviews) "Room smelled like smoke. If they vacuumed, they missed most. Breakfast was terrible. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Charles $82 nightly $91 total Apr 28 - Apr 29 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Quality-Inn-Suites.h2009.Hotel-Information) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/20000/11800/11724/1b5fb4c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11800/11724/bac50e5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/20000/11800/11724/d2976b97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/20000/11800/11724/1f011cac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Florence Near Civic Center [](https://www.expedia.com/Florence-Hotels-Days-Inn-By-Wyndham-Florence-Near-Civic-Center.h11724.Hotel-Information) Florence 7.0/10 Good (1,004 reviews) "Clean, very quiet , staff very friendly, safe place. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) María $66 nightly $74 total Apr 7 - Apr 8 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Days-Inn-By-Wyndham-Florence-Near-Civic-Center.h11724.Hotel-Information) ![Premium bedding, pillowtop beds, laptop workspace, soundproofing](https://images.trvl-media.com/lodging/1000000/10000/500/455/ef1db617.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/10000/500/455/be7cdd34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, open 10:00 AM to 8:00 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/10000/500/455/5074ad24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/500/455/af3985b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Inn [](https://www.expedia.com/Florence-Hotels-Best-Western-Inn.h455.Hotel-Information) Florence 7.8/10 Good (1,000 reviews) "Very friendly staff. The room was very spacious. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Arika $99 nightly $111 total Mar 30 - Mar 31 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Best-Western-Inn.h455.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-04-12&endDate=2026-04-13®ionId=1221&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FFlorence-Hotels.d1221.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FFlorence-Hotels.d1221.Travel-Guide-Hotels) ## Stay near popular Florence attractions ![Florence_FlorenceCivicCenter_6165605_0005](https://images.trvl-media.com/place/6165605/469ba674-c82b-48e7-81cb-5533222130a5.jpg) ### Florence Civic Center 4.0/5 (308 reviews) The Florence Center hosts everything from electrifying concerts to expansive trade shows in its modern South Carolina venue. Arrive early to navigate security and enjoy the state-of-the-art facilities. [See properties](https://www.expedia.com/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6165605) ![Florence_MagnoliaMall_6165602_0005](https://images.trvl-media.com/place/6165602/4392990f-7038-4d9a-a654-83ae3a3dcd0f.jpg) ### Magnolia Mall 4.0/5 (410 reviews) This spacious retail hub at the crossroads of two major interstates is Florence's premier shopping destination. Browse national retailers, enjoy diverse dining, or entertain the family at Tilt Studio. [See properties](https://www.expedia.com/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6165602) ![Florence_FlorenceMuseum_6162137_0005](https://images.trvl-media.com/place/6162137/dd0f8253-2cfa-4203-89de-823ddac9605e.jpg) ### Florence Museum 3.8/5 (122 reviews) The Florence County Museum showcases the Pee Dee region's heritage through William H. Johnson's artwork and Civil War artifacts. Explore rotating exhibitions and Thursday docent-led tours. [See properties](https://www.expedia.com/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6162137) ![Coastal Palmetto Tree at Sunset](https://images.trvl-media.com/place/553248635976195800/cde13ed8-6b7a-405a-b916-668039857aec.jpg) ### Palmetto Shores Lake 3.7/5 (57 reviews) Palmetto Shores Lake provides a tranquil fishing and kayaking haven in a Florence neighborhood. Locals gather at dawn to cast lines from shore, enjoying the peaceful waters and native wildlife. [See properties](https://www.expedia.com/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248635976195800) ![Golf](https://images.trvl-media.com/place/6162131/4adc6b4a-a0c5-43e1-a383-2f6a49c0c0d7.jpg) ### The Traces Golf Club 3.6/5 (16 reviews) This 27-hole golf paradise offers three distinct courses with rolling hills, strategic sand traps, and water hazards. Enjoy lush Bermuda greens before relaxing at Shankers Grille with panoramic course views. [See properties](https://www.expedia.com/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6162131) ### Eastern Carolina Agricultural Fairgrounds 3.6/5 (66 reviews) The Eastern Carolina Agricultural Fairgrounds transforms each October into a vibrant celebration of regional heritage. Experience thrilling rides and exhibits while savoring classic fair foods in this family-friendly atmosphere. [See properties](https://www.expedia.com/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6162140) ### Dr. Eddie Floyd Tennis Center This expansive complex boasts 30 courts, including rare Har-Tru clay surfaces that attract tournaments. Premium facilities include an activity center with lounges, pro shop, and locker rooms for post-match relaxation. [See properties](https://www.expedia.com/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=941624453535023104) ### Columns Plantation 3.5/5 (51 reviews) You can spend time exploring the galleries in Columns Plantation in Florence. While in this walkable area, you can savor the top-notch restaurants. [See properties](https://www.expedia.com/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532657342) ## Florence and related destinations - Florence - Mahwah - Nanuet - Katy - Texarkana - Rolla Stroll through the West Broad Street Historic District to soak up local history before exploring the Florence Museum's diverse exhibits. Catch a show at the Florence Civic Center or hunt for bargains at Magnolia Mall for a taste of modern entertainment. [See all hotels in Florence](https://www.expedia.com/Hotel-Search?startDate=2026-04-12&endDate=2026-04-13&adults=2®ionId=1221) ![Wyche Pavilion Greenville South Carolina ](https://images.trvl-media.com/place/1221/22638cec-95e4-4f53-af15-3963f8a47f19.jpg?impolicy=fcrop&w=900&h=600&p=1&q=high) ## Top Florence Hotel Reviews ![Days Inn by Wyndham Florence/I-95 North](https://images.trvl-media.com/lodging/1000000/20000/15500/15497/099eb7f9_y.jpg) ### Days Inn by Wyndham Florence/I-95 North 6/10 Okay "break fast minimal AC fine matress to soft" [](https://expedia.com/Florence-Hotels-Days-Inn-By-Wyndham-FlorenceI-95-North.h15497.Hotel-Information) ![Howard Johnson by Wyndham Florence](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/32fd6fc1_y.jpg) ### Howard Johnson by Wyndham Florence 10/10 Excellent "The room was well kept, info and items laid out right. The bathroom was very clean and the bed was comfortable. Thanks!" [](https://expedia.com/Florence-Hotels-Howard-Johnson-By-Wyndham-Florence.h11037.Hotel-Information) ![Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG](https://images.trvl-media.com/lodging/2000000/1510000/1509700/1509674/9c0353ec_y.jpg) ### Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG 10/10 Excellent "Loved it … breakfast options great as well " [](https://expedia.com/Florence-Hotels-Holiday-Inn-Ex-Hotel-Suites-Florence-I-95-I-20-Civic-Ctr.h1509674.Hotel-Information) ![Comfort Inn & Suites Florence Center Area](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/64840011_y.jpg) ### Comfort Inn & Suites Florence Center Area 8/10 Good "Room was great, breakfast very good. Front desk had no regular coffee for the room. " [](https://expedia.com/Florence-Hotels-Comfort-Inn-Suites.h38336321.Hotel-Information) ![Home2 Suites by Hilton Florence, SC](https://images.trvl-media.com/lodging/8000000/7280000/7271300/7271220/25ce2409_y.jpg) ### Home2 Suites by Hilton Florence, SC 8/10 Good "The heavy blinds we couldn’t put down so had the lights from outside shining in room " [](https://expedia.com/Florence-Hotels-Home2-Suites-By-Hilton-Florence.h7271220.Hotel-Information) ![Tru by Hilton Florence I-95](https://images.trvl-media.com/lodging/28000000/27050000/27041900/27041849/a8854f5d_y.jpg) ### Tru by Hilton Florence I-95 10/10 Excellent "The room was small and simple but it had everything we needed. We appreciated that there were plenty of towels and the soaps/shampoo etc were in dispensers in the shower and by the sink. The food was better than most family hotels. The only problem was that the electric vehicle charger was only for Teslas. If they installed a J1772 charger then all EVs could use it, even Teslas." [](https://expedia.com/Florence-Hotels-Tru-By-Hilton-Florence-I-95.h27041849.Hotel-Information) ![Microtel Inn & Suites by Wyndham Florence](https://images.trvl-media.com/lodging/1000000/200000/200000/199996/4d56e96c_y.jpg) ### Microtel Inn & Suites by Wyndham Florence 8/10 Good "Staff was exceptional, very friendly and helpful check in was quick and easy and plesant. Rooms were renovated and very clean and spacious. Beds were comfortable. Bathrooms were clean though the tub either needed to be scrubbed better or needs resurfaced because it looked a bit dingy. Shower head needs to be replaced but water pressure was great and HOT. There is NO fan in the bathroom so it gets really hot in there. The only thing i was super disappointed in was breakfast. All the reviews said it was good but it was awful. there was was muffins, bread, yogurt and cereal...and there may have been apples but they were gone. If they would do a better breakfast selection with at least a waffle maker and some kind of hot food like wggs and sausage they would have a really nice hotel. It was a convenient and safe location to the interstate and well lit. Lots of food choces around as well. Overall a great budget hotel just needs a little tweaking. " [](https://expedia.com/Florence-Hotels-Microtel-Inn-Suites-By-Wyndham-Florence.h199996.Hotel-Information) ![Quality Inn & Suites Florence Civic Center](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/8dae8685_y.jpg) ### Quality Inn & Suites Florence Civic Center 6/10 Okay "Room was very clean. Beds are on the firm side. Pool was closed even though the sign at desk stated it should be open. Breakfast was extremely minimal. Front desk agent was very rude and acted as if I was bothering her. Horrible customer service skills. This is a one and done stay." [](https://expedia.com/Florence-Hotels-Quality-Inn-And-Suites-Civic.h11535.Hotel-Information) ![Staybridge Suites Florence - Civic Center by IHG](https://images.trvl-media.com/lodging/22000000/21760000/21758600/21758593/89338f8a_y.jpg) ### Staybridge Suites Florence - Civic Center by IHG 10/10 Excellent "Breakfast was good and clean" [](https://expedia.com/Florence-Hotels-Staybridge-Suites-Florence-Civic-Center.h21758593.Hotel-Information) ## More cheap stays in Florence ![Microtel Inn & Suites by Wyndham Florence](https://images.trvl-media.com/lodging/1000000/200000/200000/199996/4d56e96c_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Microtel Inn & Suites by Wyndham Florence 1912 Enterprise Dr Florence SC $60 nightly $67 total Apr 22 - Apr 23 Total with taxes and fees 6.8/10 (1,003 reviews) [](https://expedia.com/Florence-Hotels-Microtel-Inn-Suites-By-Wyndham-Florence.h199996.Hotel-Information) ![Howard Johnson by Wyndham Florence](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/32fd6fc1_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Howard Johnson by Wyndham Florence 2038 W Lucas Street Florence SC $60 nightly $68 total Apr 26 - Apr 27 Total with taxes and fees 8.6/10 Excellent! (2,604 reviews) [](https://expedia.com/Florence-Hotels-Howard-Johnson-By-Wyndham-Florence.h11037.Hotel-Information) ![Days Inn by Wyndham Florence/I-95 North](https://images.trvl-media.com/lodging/1000000/20000/15500/15497/099eb7f9_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Days Inn by Wyndham Florence/I-95 North 2111 West Lucas St/I-95 Florence SC $61 nightly $69 total Apr 7 - Apr 8 Total with taxes and fees 6.8/10 (1,005 reviews) [](https://expedia.com/Florence-Hotels-Days-Inn-By-Wyndham-FlorenceI-95-North.h15497.Hotel-Information) ![Quality Inn & Suites Florence Civic Center](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/8dae8685_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Quality Inn & Suites Florence Civic Center 150 Dunbarton Dr Florence SC $93 nightly $104 total Mar 30 - Mar 31 Total with taxes and fees 8.4/10 Very Good! (40 reviews) [](https://expedia.com/Florence-Hotels-Quality-Inn-And-Suites-Civic.h11535.Hotel-Information) ![Comfort Inn & Suites Florence Center Area](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/64840011_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Comfort Inn & Suites Florence Center Area 527 Woody Jones Blvd Florence SC $101 nightly $114 total Apr 26 - Apr 27 Total with taxes and fees 9/10 Wonderful! (1,242 reviews) [](https://expedia.com/Florence-Hotels-Comfort-Inn-Suites.h38336321.Hotel-Information) ![Woodspring Suites Sumter Near Shaw Afb](https://images.trvl-media.com/lodging/114000000/113640000/113638700/113638614/9722c1f7_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Woodspring Suites Sumter Near Shaw Afb 2715 Broad Street Sumter SC $144 nightly $161 total Apr 5 - Apr 6 Total with taxes and fees 8.2/10 Very Good! (185 reviews) [](https://expedia.com/Sumter-Hotels-Woodspring-Suites-Sumter-Near-Shaw-Afb.h113638614.Hotel-Information) ## Hotels in Florence with star-rating ![4 Star Hotels](https://images.trvl-media.com/lodging/1000000/30000/23700/23677/6ae928dd_z.jpg) 4 Star Hotels 1 properties [](https://expedia.com/4Star-Florence-Hotels.s40-0-d1221.Travel-Guide-Filter-Hotels) ![3 Star Hotels](https://images.trvl-media.com/lodging/20000000/19690000/19681400/19681371/84fffc75_z.jpg) 3 Star Hotels 58 properties [](https://expedia.com/3Star-Florence-Hotels.s30-0-d1221.Travel-Guide-Filter-Hotels) ![2 Star Hotels](https://images.trvl-media.com/lodging/92000000/91830000/91828000/91827910/6717a2ac_z.jpg) 2 Star Hotels 111 properties [](https://expedia.com/2Star-Florence-Hotels.s20-0-d1221.Travel-Guide-Filter-Hotels) ## Price trends for hotels in Florence | Less expensive | More expensive | Next month | | -------------- | -------------- | ---------- | | February | September | $102 | | Month | Price | | --------- | ----- | | January | $101 | | February | $99 | | March | $99 | | April | $102 | | May | $102 | | June | $104 | | July | $102 | | August | $102 | | September | $109 | | October | $102 | | November | $99 | | December | $99 | Price trend information excludes taxes and fees and is based on base rates for a nightly stay for 2 adults found in the last 7 days on our site and averaged for commonly viewed hotels in Florence. Select dates and complete search for nightly totals inclusive of taxes and fees. ## Find out more about Florence ### Top reasons to visit Florence - **Exciting Motor Racing:** Experience the thrill of motor racing events that draw enthusiasts from all over. - **Cultural Attractions:** Visit the Florence County Museum and local art galleries to immerse yourself in the area's rich culture. - **Beautiful Parks:** Enjoy outdoor adventures in serene urban parks, perfect for families and nature lovers. - **Shopping Opportunities:** Explore local shopping centers offering a variety of unique finds and experiences. - **Welcoming Accommodations:** Choose from a range of comfortable and budget-friendly lodging options catering to diverse needs. ### Find great hotels in Florence Florence, South Carolina, offers a variety of accommodation options to suit every traveler's needs. From pet-friendly hotels to welcoming spaces for LGBTQIA guests, you'll find a range of services that cater to both leisure and business travelers. Whether you're searching for a hotel in downtown Florence or a cozy motel, this charming city has the perfect lodging to make your stay enjoyable and comfortable. - **[Howard Johnson by Wyndham Florence: ](https://www.expedia.com/Florence-Hotels-Howard-Johnson-By-Wyndham-Florence.h11037.Hotel-Information)** A budget-friendly option with a cozy atmosphere, Howard Johnson by Wyndham Florence boasts a commendable guest rating of 8.6\. This motel-style accommodation is perfect for families and business travelers alike, offering essential amenities to ensure a comfortable stay. Families will appreciate the complimentary crib service and essential first aid kits available on-site. The property's family-friendly vibe, combined with its convenient location in Florence, makes it an ideal choice for those seeking a homey retreat. - **[Park Inn by Radisson Florence, SC: ](https://www.expedia.com/Florence-Hotels-Park-Inn-By-Radisson-Florence.h47086732.Hotel-Information)** With a guest rating of 9.0, Park Inn by Radisson Florence, SC stands out as a pet-friendly haven that caters to both leisure and business travelers. This budget-friendly hotel offers a welcoming atmosphere for furry companions, with amenities such as food and water bowls and a waived fee for service animals. Guests can expect comfortable accommodations, modern facilities, and an overall pleasant stay in Florence. Its convenient location is perfect for exploring local attractions while enjoying the comfort of a pet-friendly environment. - **[Days Inn by Wyndham Florence/I-95 North: ](https://www.expedia.com/Florence-Hotels-Days-Inn-By-Wyndham-FlorenceI-95-North.h15497.Hotel-Information)** Another great budget-friendly choice, Days Inn by Wyndham Florence/I-95 North is rated highly for its family and pet-friendly features. With a guest rating of 8.4, this motel-style lodging provides essential amenities like complimentary cribs for families traveling with little ones. Pets are also welcome, with policies that include waived fees for service animals. Its convenient proximity to I-95 makes it a great stop for travelers looking for a comforting and accommodating experience in Florence. ### Where to stay near Florence Florence, South Carolina, offers a delightful blend of southern hospitality and family-friendly attractions. Explore top picks like the Florence County Museum or enjoy the great outdoors at nearby parks. With its welcoming vibe and budget-friendly options, Florence is a perfect vacation spot for families seeking adventure and entertainment. Don't miss the chance to experience the friendly atmosphere and charm of the surrounding neighborhoods, making your stay both memorable and enjoyable. - **[Darlington: ](https://www.expedia.com/Darlington-Hotels.d7558.Travel-Guide-Hotels)** Located 10 miles from Florence, Darlington is a vibrant city known for its rich sports culture and outdoor adventures. Visitors flock here primarily during the summer months, particularly from July to September, drawn by thrilling motor racing events and recreational activities. The city boasts key attractions like the Darlington Raceway, where adrenaline junkies can experience high-speed action, along with local lakes ideal for fishing and picnicking. Shoppers will appreciate the various shopping centers that offer a blend of local and national brands. Whether you're looking to enjoy a day out in nature or catch an exciting race, Darlington has something for everyone. - **[Timmonsville: ](https://www.expedia.com/Timmonsville-Hotels.d180880.Travel-Guide-Hotels)** Just 11 miles from Florence, Timmonsville is a charming city that perfectly balances family-friendly activities with thrilling sports experiences. Peak visitor times occur in May, July, and September, making it an excellent destination for summer getaways. The city is home to popular venues like the local shopping mall and stadium, which hosts exciting events throughout the year. With its urban parks offering green spaces for leisure activities and family outings, Timmonsville ensures that visitors can enjoy a variety of experiences. It's an ideal stop for those seeking adventure and quality time with loved ones. - **[Effingham: ](https://www.expedia.com/Effingham-Hotels.d553248635975849973.Travel-Guide-Hotels)** Situated 10 miles from Florence, Effingham is a delightful city that caters to outdoor enthusiasts and families alike. With peak travel times in June and July, visitors are drawn to its scenic lakes and entertainment facilities. Outdoor adventures abound, with options like boardwalk strolls and exhilarating days at the water park. The charming tourist precinct is perfect for leisurely exploration, offering a mix of local eateries and shops. Effingham is also a romantic getaway spot, making it a great choice for couples seeking a peaceful escape amidst nature's beauty. ### Things to do near Florence Florence, South Carolina, offers a delightful mix of family-friendly activities and outdoor adventures. Visitors can enjoy the excitement of motor racing, explore the traces golf club, and take advantage of excellent shopping experiences at local centers. Don't miss out on sightseeing opportunities and day trips that showcase the area's charm and attractions, making it an ideal destination for a fun-filled vacation. **Shopping** In downtown Florence, explore the charming shops along Evans Street for unique gifts and souvenirs. If you're up for a drive, head to the Florence Mall, where you can find popular retail stores and dining options for a full day of shopping. Don't miss the local markets for handmade treasures. **Recreation** Experience the luxurious [Marlboro Country Club](https://www.expedia.com/Marlboro-Country-Club-Hotels.0-l6310543-0.Travel-Guide-Filter-Hotels), located 30 miles from Florence. Enjoy upscale amenities, relax in a serene environment, and indulge in recreational activities such as golf and tennis for a refreshing retreat. Unwind in style while surrounded by beautiful landscapes and a welcoming atmosphere. **Adventure** Explore the scenic areas of Florence County at the Lynches River County Park, where you can kayak along the river, hike through beautiful trails, and enjoy a picnic. For thrill-seekers, head to the Darlington Raceway for a chance to experience the excitement of NASCAR racing events. **Nightlife** Explore the vibrant nightlife at The Florence Center for live events and concerts. Enjoy cocktails and a lively atmosphere at The Grille, or unwind with a cold beer at 2nd Street Bar and Grill, known for its friendly vibe and great food. \*Distances are measured in a straight line; actual driving distances may vary depending on the route. ### Booking tips and Expedia advantages for Florence - **The most and least expensive months on average to stay in a hotel:** The cheapest months to stay in Florence are January to February and November, where the prices are slightly lower. This is in comparison to April and August to September, where prices are slightly higher. - **The most and least expensive days on average to stay in a hotel:** The least expensive day to stay in Florence is Monday. The most expensive day to stay in Florence is Saturday. - **Find cheap hotels on Expedia:** Utilize Expedia's search tool to refine your preferences, such as your budget, desired location, and the type of hotel you prefer. To find the best prices and deals, simply arrange the price filter from lowest to highest. - **Consider bundling your trip:** You can save money by combining your hotel stay in Florence with your flights and activities by booking a package through Expedia. ### Find the best attractions in Florence Florence, South Carolina, offers a delightful mix of family-friendly, outdoor, and entertainment activities. Visitors can explore local attractions such as the fairgrounds, art museums, and urban parks, making it an ideal destination for those seeking a vibrant city experience. Whether you're enjoying a day at the fair or appreciating art, Florence has something to cater to every traveler's interests. - **[Eastern Carolina Agricultural Fairgrounds: ](https://www.expedia.com/Eastern-Carolina-Agricultural-Fairgrounds-Hotels.0-l6162140-0.Travel-Guide-Filter-Hotels)** Experience the lively atmosphere of the Eastern Carolina Agricultural Fairgrounds, where you can enjoy family-friendly events, local exhibitions, and exciting rides. This venue is perfect for soaking in the community spirit and creating lasting memories with your loved ones. - **[Florence Museum: ](https://www.expedia.com/Florence-Museum-Hotels.0-l6162137-0.Travel-Guide-Filter-Hotels)** Immerse yourself in the rich culture of the region at the Florence Museum. Explore a diverse collection of local art and historical artifacts that showcase the vibrant heritage of Florence. Engaging exhibits make this a cultural gem for art enthusiasts and history buffs alike. - **[Palmetto Shores Lake: ](https://www.expedia.com/Palmetto-Shores-Lake-Hotels.0-l553248635976195800-0.Travel-Guide-Filter-Hotels)** Relax by the serene waters of Palmetto Shores Lake, an ideal spot for outdoor activities, picnics, or romantic strolls. Enjoy the picturesque scenery and beach vibes, making it a perfect escape from the hustle and bustle of daily life. ### Best time to go to Florence The best time to visit Florence can depend on the weather and when visitor numbers rise and fall. The hottest average temperature in Florence falls in July, when visitor numbers are slightly high and weather is mostly sunny with light rain. The coolest average temperature in Florence falls in January, visitor numbers are slightly low and weather is mostly sunny with light rain. | **![calendar](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/calendar.png)Calendar Month** | **![temperature](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__hot.png)Temperature** | **![rain](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__rain.png)Precipitation** | **![mostly](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/21/weather__day_mostly_cloudy.png)Cloudiness** | **![occupation](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/peoplebex.png)Occupancy** | **![price](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/currency_dollar.png)Pricing** | | ---------------------------------------------------------------------------------------------------------------- | -------------------------------------------------------------------------------------------------------------------- | ---------------------------------------------------------------------------------------------------------------- | ---------------------------------------------------------------------------------------------------------------------------- | -------------------------------------------------------------------------------------------------------------- | ------------------------------------------------------------------------------------------------------------- | | January | 45.5°F (7.5°C) | Light Rain | Mostly Sunny | Slightly Low | Slightly Low | | February | 49.3°F (9.6°C) | Light Rain | Mostly Sunny | Slightly Low | Slightly Low | | March | 55.2°F (12.9°C) | Light Rain | Mostly Sunny | Average | Average | | April | 63.5°F (17.5°C) | Light Rain | Mostly Sunny | Average | Slightly High | | May | 71.2°F (21.8°C) | Light Rain | Mostly Sunny | Average | Average | | June | 78.3°F (25.7°C) | Light Rain | Mostly Sunny | Slightly High | Average | | July | 81.1°F (27.3°C) | Light Rain | Mostly Sunny | Slightly High | Average | | August | 79.3°F (26.3°C) | Light Rain | Mostly Sunny | Slightly High | Slightly High | | September | 74.7°F (23.7°C) | Light Rain | Mostly Sunny | Average | Slightly High | | October | 65.1°F (18.4°C) | Light Rain | Mostly Sunny | Slightly Low | Average | | November | 54.7°F (12.6°C) | Light Rain | Mostly Sunny | Average | Slightly Low | | December | 49.5°F (9.7°C) | Light Rain | Mostly Sunny | Average | Average | ### The nearest major airports for your trip to Florence Florence, South Carolina, can be conveniently accessed via three major airports. Charlotte Douglas International Airport ([CLT](https://www.expedia.com/Charlotte-Douglas-Intl-Airport-Hotels.0-aCLT-0.Travel-Guide-Filter-Hotels)) is 97 miles away, with nearby hotels like [The Ritz-Carlton](https://www.expedia.com/Charlotte-Hotels-The-Ritz-Carlton.h2903551.Hotel-Information) and JW Marriott, both within a 6-mile radius. Charleston International Airport ([CHS](https://www.expedia.com/Charleston-Intl-Airport-Hotels.0-aCHS-0.Travel-Guide-Filter-Hotels)) is 92 miles distant, featuring luxurious options like [The Charleston Place](https://www.expedia.com/Charleston-Hotels-Charleston-Place.h28504.Hotel-Information) and [Hotel Bennett](https://www.expedia.com/Charleston-Hotels-Hotel-Bennett.h22649862.Hotel-Information), located 9 miles from the airport. [MYR](https://www.expedia.com/Myrtle-Beach-Intl-Airport-Hotels.0-aMYR-0.Travel-Guide-Filter-Hotels)tle Beach International Airport (MYR) is the closest, at 60 miles away, with accommodations such as Hilton Grand Vacations Club and DoubleTree Resort by Hilton, both within 3 miles. Each airport offers various transportation services to and from these hotels, ensuring a smooth travel experience. ## Frequently asked questions ### What is the best area to stay in Florence? > This area is centrally located and offers easy access to the city's main convention center and entertainment venues. You'll find a selection of hotels, restaurants, and shops concentrated around this hub, making it a practical choice for travelers. > > > For business travelers, staying near the Florence Center is ideal due to its proximity to the convention facilities and major roadways. Hotels here often cater to business needs with amenities like meeting spaces and high-speed internet. > > > Couples often appreciate this area for its accessibility to dining options and entertainment without needing to travel far. ### What are the best hotels in Florence that travelers recommend? > The Hampton Inn & Suites Florence Center, with a strong 9.0 rating, is much-loved for its convenient location near Florence Veterans Park and Magnolia Mall. Guests frequently praise the extremely helpful staff and the clean, great rooms with comfy beds. The complimentary breakfast is also a favorite among visitors. > > > Another highly recommended option is the Hampton Inn & Suites Florence-North-I-95, also with an impressive 9.0 rating. Travelers consistently highlight the comfortable and clean rooms, the friendly and helpful staff, and the excellent breakfast. Its location is considered nice, and easy parking is an added convenience. ### What are the best family hotels in Florence? > The 3-star Staybridge Suites Florence - Civic Center by IHG, with an impressive 9.4 rating, is an excellent choice for families. It offers a variety of amenities to ensure a comfortable stay, including a pool with sun loungers, a pool especially for children, and an outdoor pool. Guests frequently praise the free and delicious breakfast, the comfortable and clean rooms, and the friendly and extremely helpful staff. It is conveniently located near Florence Veterans Park and Magnolia Mall. > > > Another great option is the 3-star Aloft Florence, rated 8.6\. This hotel provides spacious and clean rooms, free cribs, and sofa beds, making it suitable for families. It features an indoor pool and offers free WiFi and free self-parking. Travelers often comment on the attentive and helpful staff, the nice bar, and the convenient location near Florence Veterans Park and Magnolia Mall. > > > The 3-star Homewood Suites by Hilton Florence, with an 8.4 rating, is also a strong contender for families. It offers spacious and clean rooms, connecting rooms, and free cribs, along with a pool. Guests appreciate the complimentary breakfast, with options for grab-and-go. The friendly and attentive staff, along with the good location near Florence Veterans Park and Magnolia Mall, are frequently highlighted in reviews. Find more [child-friendly accommodations in Florence](https://www.expedia.com/Florence-Hotels-Family-Hotel.0-0-d1221-tFamilyHotel.Travel-Guide-Filter-Hotels) ### What are the best spa hotels in Florence? > This 3-star hotel, with an 8.8 rating, offers a full-service spa with a wide array of treatments. Guests can indulge in facial treatments, aromatherapy, body wraps, and various massages including Swedish, hot stone, deep tissue, and even couples' treatments. The spa also features detoxification wraps, ensuring wellness experiences. Many guests have praised the warm and great customer service from the staff, particularly at the front desk, and appreciate the hotel's convenient location. See all [spa hotels in Florence](https://www.expedia.com/Florence-Hotels-Spa-Hotel.0-0-d1221-tSpaHotel.Travel-Guide-Filter-Hotels) ### What hotels in Florence offer free breakfast? > The 3-star Staybridge Suites Florence - Civic Center by IHG, boasting an excellent 9.4 rating, provides free continental breakfast daily. Guests frequently praise the comfortable and clean rooms, as well as the friendly and extremely helpful staff. The hotel also features an outdoor pool, including a children's pool, and is conveniently located just 0.6 miles from Florence Veterans Park. > > > Another great option is the Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG, with a high rating of 9.2\. This hotel offers a free buffet breakfast and free WiFi. Customers often highlight the friendly staff and the convenient location, also just 0.6 miles from Florence Veterans Park. > > > The Comfort Inn & Suites Florence Center Area, rated 9.2, is another excellent choice for a hotel with free breakfast, offering a complimentary continental breakfast daily. Guests appreciate the spacious and clean rooms, the great breakfast, and its convenient, quiet location, being only 0.1 miles from Florence Veterans Park. Find more [hotels with free breakfast in Florence](https://www.expedia.com/Florence-Hotels-Hotels-With-Complimentary-Breakfast.0-0-d1221-tHotelswithComplimentaryBreakfast.Travel-Guide-Filter-Hotels) ### What are the top pet-friendly hotels in Florence? > The 3-star La Quinta Inn & Suites by Wyndham Florence, with an 8.0 rating, permits both dogs and cats. Guests frequently mention the nice and clean rooms, excellent and friendly staff, and great breakfast. Its location is also noted as convenient. > > > Another excellent choice is the 3-star Staybridge Suites Florence - Civic Center by IHG, which boasts an impressive 9.4 rating. This hotel welcomes both dogs and cats and offers a complimentary continental breakfast. Guests praise the comfortable and clean rooms, the friendly and extremely helpful staff, and the delicious breakfast. The beautiful and clean lobby is also a highlight, and its location is considered easily accessible and great, being just 0.6 miles from Florence Veterans Park and 0.8 miles from Magnolia Mall. See more [pet-friendly hotels in Florence](https://www.expedia.com/Florence-Hotels-Pet-Friendly-Hotel.0-0-d1221-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) ### What are the best budget hotels in Florence? > The 3-star TownePlace Suites by Marriott Florence, with a 9.0 rating, offers complimentary grocery shopping services, free breakfast, and free self-parking. Guests consistently praise its great breakfast and comfortable rooms, and it's conveniently located just 0.1 miles from Florence Veterans Park. > > > Another excellent option is the 3-star Residence Inn Marriott Florence, rated 8.8\. This hotel also provides a complimentary full breakfast, free grocery shopping service, and free WiFi. Travelers frequently highlight its comfortable and clean rooms, delicious breakfast, and wonderful staff. It is situated 0.2 miles from Florence Veterans Park, making it a great location for visitors. View all [budget hotels in Florence](https://www.expedia.com/Florence-Hotels-Cheap-Hotels.0-0-d1221-tCheapHotels.Travel-Guide-Filter-Hotels) ### What are the most romantic hotels in Florence for couples? > The 3-star Hotel Florence, Tapestry Collection by Hilton, with an 8.8 rating, offers a full-service spa with a variety of treatments including couples' treatment rooms, Swedish massage, deep tissue massage, and hot stone massage. Guests have noted the great location and warm staff, making it a pleasant choice for a relaxing getaway. The Florence Museum is also just 0.9 miles away. > > > Another excellent option is the 3-star Residence Inn Marriott Florence, rated 8.8\. This hotel provides comfortable and clean rooms, and guests frequently praise the wonderful staff and delicious breakfast. It also features a hot tub, superb for unwinding together. See all [romantic hotels in Florence](https://www.expedia.com/Florence-Hotels-Romantic-Hotel.0-0-d1221-tRomanticHotel.Travel-Guide-Filter-Hotels) ### What are the best hotels in Florence near Florence Veterans Park? > The Comfort Inn & Suites Florence Center Area, with a 9.2 rating, is an excellent choice as it is located just 0.1 miles from Florence Veterans Park. Guests frequently praise the friendly and helpful staff, the spacious and clean rooms, and the great breakfast. Its convenient and quiet location is also a highlight. > > > Another highly-rated option is the 3-star Staybridge Suites Florence - Civic Center by IHG, which has a 9.4 rating. This hotel is 0.6 miles from Florence Veterans Park and offers a pool, free breakfast, and outdoor sun loungers. Guests often mention the comfortable and clean rooms, the extremely helpful staff, and the delicious free breakfast. > > > The Hampton Inn & Suites Florence Center, rated 9.0, is 0.4 miles from Florence Veterans Park. This hotel provides a pool, free breakfast, and free WiFi. Travelers consistently praise the amazing and helpful staff, the clean rooms, and the comfortable beds. ### When is the best time to go to Florence? > These seasons offer pleasant weather with comfortable temperatures and lower humidity, making it ideal for exploring the city's outdoor attractions and enjoying local events. You'll find it comfortable to stroll through the historic downtown or visit the Florence Veterans Park without the intense heat of summer or the chill of winter. > > > For couples seeking a relaxing getaway, spring offers beautiful blooming flowers and a generally calm atmosphere for dining al fresco or enjoying a quiet walk. ### Can I cancel my hotel reservation on Expedia? ### How can I save on a Florence hotel booking with Expedia? > \*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo. ### How much is the nightly rate at a Florence hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - [Hotels near Mcleod Regional Medical Center ](https://www.expedia.com/Mcleod-Regional-Medical-Center-Hotels.0-l6162127-0.Travel-Guide-Filter-Hotels) - [Hotels near Florence Station ](https://www.expedia.com/Florence-Station-Hotels.d6195493.Travel-Guide-Hotels) - [Hotels near Florence Museum ](https://www.expedia.com/Florence-Museum-Hotels.0-l6162137-0.Travel-Guide-Filter-Hotels) - [Hotels near Florence National Cemetery ](https://www.expedia.com/Florence-National-Cemetery-Hotels.0-l553248621532657341-0.Travel-Guide-Filter-Hotels) - [Hotels near Florence Regional ](https://www.expedia.com/Florence-Regional-Airport-Hotels.0-aFLO-0.Travel-Guide-Filter-Hotels) - [Flights from Florence Regional ](https://www.expedia.com/lp/airports/flo/flights-from-florence-regional-airport) - 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[Flights from Washington (DCA) to Florence (FLO) ](https://www.expedia.com/lp/flights/dca/flo/washington-to-florence) - [Flights from Houston (IAH) to Florence (FLO) ](https://www.expedia.com/lp/flights/iah/flo/houston-to-florence) - [Flights from New York (LGA) to Florence (FLO) ](https://www.expedia.com/lp/flights/lga/flo/new-york-to-florence) - [Flights from Columbia (CAE) to Florence (FLO) ](https://www.expedia.com/lp/flights/cae/flo/columbia-to-florence) - [Flights from Jacksonville (JAX) to Florence (FLO) ](https://www.expedia.com/lp/flights/jax/flo/jacksonville-to-florence) - [Flights from Chicago (ORD) to Florence (FLO) ](https://www.expedia.com/lp/flights/ord/flo/chicago-to-florence) - [Flights from Baltimore (BWI) to Florence (FLO) ](https://www.expedia.com/lp/flights/bwi/flo/baltimore-to-florence) - [Flights from Philadelphia (PHL) to Florence (FLO) ](https://www.expedia.com/lp/flights/phl/flo/philadelphia-to-florence) - [Flights from Hartford (BDL) to Florence (FLO) ](https://www.expedia.com/lp/flights/bdl/flo/hartford-to-florence) - [Flights from Tampa (TPA) to Florence (FLO) ](https://www.expedia.com/lp/flights/tpa/flo/tampa-to-florence) - [Flights from Greenville (GSP) to Florence (FLO) ](https://www.expedia.com/lp/flights/gsp/flo/greenville-to-florence) - [Flights from Dallas (DFW) to Florence (FLO) ](https://www.expedia.com/lp/flights/dfw/flo/dallas-to-florence) - [Flights from Rochester (ROC) to Florence (FLO) ](https://www.expedia.com/lp/flights/roc/flo/rochester-to-florence) - [Flights from Orlando (MCO) to Florence (FLO) ](https://www.expedia.com/lp/flights/mco/flo/orlando-to-florence) - [Flights from Oklahoma City (OKC) to Florence (FLO) ](https://www.expedia.com/lp/flights/okc/flo/oklahoma-city-to-florence) - [Flights from Huntsville (HSV) to Florence (FLO) ](https://www.expedia.com/lp/flights/hsv/flo/huntsville-to-florence) - [Flights from Los Angeles (LAX) to Florence (FLO) ](https://www.expedia.com/lp/flights/lax/flo/los-angeles-to-florence) - [Flights from Phoenix (PHX) to Florence (FLO) ](https://www.expedia.com/lp/flights/phx/flo/phoenix-to-florence) - [Flights from Fort Lauderdale (FLL) to Florence (FLO) ](https://www.expedia.com/lp/flights/fll/flo/fort-lauderdale-to-florence) - [Flights from Miami (MIA) to Florence (FLO) ](https://www.expedia.com/lp/flights/mia/flo/miami-to-florence) - [Flights from Wilmington (ILM) to Florence (FLO) ](https://www.expedia.com/lp/flights/ilm/flo/wilmington-to-florence) - [Flights from Raleigh (RDU) to Florence (FLO) ](https://www.expedia.com/lp/flights/rdu/flo/raleigh-to-florence) - [Flights from Savannah (SAV) to Florence (FLO) ](https://www.expedia.com/lp/flights/sav/flo/savannah-to-florence) - [Flights from Memphis (MEM) to Florence (FLO) ](https://www.expedia.com/lp/flights/mem/flo/memphis-to-florence) - [Flights from San Diego (SAN) to Florence (FLO) ](https://www.expedia.com/lp/flights/san/flo/san-diego-to-florence) - [Flights from Sarasota (SRQ) to Florence (FLO) ](https://www.expedia.com/lp/flights/srq/flo/sarasota-to-florence) - [Flights from Denver (DEN) to Florence (FLO) ](https://www.expedia.com/lp/flights/den/flo/denver-to-florence) - [Flights from Seattle (SEA) to Florence (FLO) ](https://www.expedia.com/lp/flights/sea/flo/seattle-to-florence) - [Flights from Pittsburgh (PIT) to Florence (FLO) ](https://www.expedia.com/lp/flights/pit/flo/pittsburgh-to-florence) - [Flights from Detroit (DTW) to Florence (FLO) ](https://www.expedia.com/lp/flights/dtw/flo/detroit-to-florence) - [Flights from Albany (ALB) to Florence (FLO) ](https://www.expedia.com/lp/flights/alb/flo/albany-to-florence) - [Flights from Buffalo (BUF) to Florence (FLO) ](https://www.expedia.com/lp/flights/buf/flo/buffalo-to-florence) - [Flights from Lexington (LEX) to Florence (FLO) ](https://www.expedia.com/lp/flights/lex/flo/lexington-to-florence) - [Flights from Louisville (SDF) to Florence (FLO) ](https://www.expedia.com/lp/flights/sdf/flo/louisville-to-florence) - [Flights from Cleveland (CLE) to Florence (FLO) ](https://www.expedia.com/lp/flights/cle/flo/cleveland-to-florence) - [Flights from Austin (AUS) to Florence (FLO) ](https://www.expedia.com/lp/flights/aus/flo/austin-to-florence) - [Flights from San Francisco (SFO) to Florence (FLO) ](https://www.expedia.com/lp/flights/sfo/flo/san-francisco-to-florence) - [Flights from Greensboro (GSO) to Florence (FLO) ](https://www.expedia.com/lp/flights/gso/flo/greensboro-to-florence) - [Flights from Columbus (CMH) to Florence (FLO) ](https://www.expedia.com/lp/flights/cmh/flo/columbus-to-florence) - [Flights from Richmond (RIC) to Florence (FLO) ](https://www.expedia.com/lp/flights/ric/flo/richmond-to-florence) - [Flights from Augusta (AGS) to Florence (FLO) ](https://www.expedia.com/lp/flights/ags/flo/augusta-to-florence) - [Flights from Tucson (TUS) to Florence (FLO) ](https://www.expedia.com/lp/flights/tus/flo/tucson-to-florence) - [Flights from Birmingham (BHM) to Florence (FLO) ](https://www.expedia.com/lp/flights/bhm/flo/birmingham-to-florence) - [Flights from Syracuse (SYR) to Florence (FLO) ](https://www.expedia.com/lp/flights/syr/flo/syracuse-to-florence) - [Flights from Chattanooga (CHA) to Florence (FLO) ](https://www.expedia.com/lp/flights/cha/flo/chattanooga-to-florence) - [Flights from Dayton (DAY) to Florence (FLO) ](https://www.expedia.com/lp/flights/day/flo/dayton-to-florence) - [Flights from Indianapolis (IND) to Florence (FLO) ](https://www.expedia.com/lp/flights/ind/flo/indianapolis-to-florence) - [Flights from Norfolk (ORF) to Florence (FLO) ](https://www.expedia.com/lp/flights/orf/flo/norfolk-to-florence) - [Flights from Little Rock (LIT) to Florence (FLO) ](https://www.expedia.com/lp/flights/lit/flo/little-rock-to-florence) - [Flights from Minneapolis (MSP) to Florence (FLO) ](https://www.expedia.com/lp/flights/msp/flo/minneapolis-to-florence) - [Flights from Knoxville (TYS) to Florence (FLO) ](https://www.expedia.com/lp/flights/tys/flo/knoxville-to-florence) - [Flights from Newburgh (SWF) to Florence (FLO) ](https://www.expedia.com/lp/flights/swf/flo/newburgh-to-florence) - [Flights from London (LHR) to Florence (FLO) ](https://www.expedia.com/lp/flights/lhr/flo/london-to-florence) - [Flights from Daytona Beach (DAB) to Florence (FLO) ](https://www.expedia.com/lp/flights/dab/flo/daytona-beach-to-florence) - [Flights from Milwaukee (MKE) to Florence (FLO) ](https://www.expedia.com/lp/flights/mke/flo/milwaukee-to-florence) - [Flights from Sacramento (SMF) to Florence (FLO) ](https://www.expedia.com/lp/flights/smf/flo/sacramento-to-florence) - [Flights from Colorado Springs (COS) to Florence (FLO) ](https://www.expedia.com/lp/flights/cos/flo/colorado-springs-to-florence) - [Flights from Kansas City (MCI) to Florence (FLO) ](https://www.expedia.com/lp/flights/mci/flo/kansas-city-to-florence) - [Flights from Providence (PVD) to Florence (FLO) ](https://www.expedia.com/lp/flights/pvd/flo/providence-to-florence) - [Flights from El Paso (ELP) to Florence (FLO) ](https://www.expedia.com/lp/flights/elp/flo/el-paso-to-florence) - [Flights from Cincinnati (CVG) to Florence (FLO) ](https://www.expedia.com/lp/flights/cvg/flo/cincinnati-to-florence) - [Flights from West Palm Beach (PBI) to Florence (FLO) ](https://www.expedia.com/lp/flights/pbi/flo/west-palm-beach-to-florence) - [Flights from New Orleans (MSY) to Florence (FLO) ](https://www.expedia.com/lp/flights/msy/flo/new-orleans-to-florence) - [Flights from Asheville (AVL) to Florence (FLO) ](https://www.expedia.com/lp/flights/avl/flo/asheville-to-florence) - [Flights from Gainesville (GNV) to Florence (FLO) ](https://www.expedia.com/lp/flights/gnv/flo/gainesville-to-florence) - [Flights from Missoula (MSO) to Florence (FLO) ](https://www.expedia.com/lp/flights/mso/flo/missoula-to-florence) - [Flights from Lancaster (LNS) to Florence (FLO) ](https://www.expedia.com/lp/flights/lns/flo/lancaster-to-florence) - [Flights from Nairobi (NBO) to Florence (FLO) ](https://www.expedia.com/lp/flights/nbo/flo/nairobi-to-florence) - [Flights from New Haven (HVN) to Florence (FLO) ](https://www.expedia.com/lp/flights/hvn/flo/new-haven-to-florence) - [Flights from Tallahassee (TLH) to Florence (FLO) ](https://www.expedia.com/lp/flights/tlh/flo/tallahassee-to-florence) - [Flights from Harrisburg (MDT) to Florence (FLO) ](https://www.expedia.com/lp/flights/mdt/flo/harrisburg-to-florence) - [Flights from Washington (IAD) to Florence (FLO) ](https://www.expedia.com/lp/flights/iad/flo/washington-to-florence) - [Flights from Boise (BOI) to Florence (FLO) ](https://www.expedia.com/lp/flights/boi/flo/boise-to-florence) - [Flights from Allentown (ABE) to Florence (FLO) ](https://www.expedia.com/lp/flights/abe/flo/allentown-to-florence) - [Flights from Salt Lake City (SLC) to Florence (FLO) ](https://www.expedia.com/lp/flights/slc/flo/salt-lake-city-to-florence) - [Flights from Montgomery (MGM) to Florence (FLO) ](https://www.expedia.com/lp/flights/mgm/flo/montgomery-to-florence) - [Flights from Eugene (EUG) to Florence (FLO) ](https://www.expedia.com/lp/flights/eug/flo/eugene-to-florence) - [Flights from Fayetteville (FAY) to Florence (FLO) ](https://www.expedia.com/lp/flights/fay/flo/fayetteville-to-florence) - [Mcleod Regional Medical Center ](https://www.expedia.com/Mcleod-Regional-Medical-Center-Florence.d6162127.Vacation-Attraction) - [Florence Museum ](https://www.expedia.com/Florence-Museum-Florence.d6162137.Vacation-Attraction) - [Car rentals near Mcleod Regional Medical Center ](https://www.expedia.com/Car-Rentals-In-Mcleod-Regional-Medical-Center.d6162127.Car-Rental-Guide) - [Hertz Rental Cars in Florence Regional ](https://www.expedia.com/Hertz-Car-Rentals-In-Florence-Regional.d6027805-c40.Car-Rental-Guide-Suppliers) - [Avis Rental Cars in Florence Regional ](https://www.expedia.com/Avis-Car-Rentals-In-Florence-Regional.d6027805-c41.Car-Rental-Guide-Suppliers) - [Car rental Florence Airport (FLO) ](https://www.expedia.com/Car-Rentals-In-Florence-Regional.d6027805.Car-Rental-Guide) - [Budget Rental Cars in Florence Regional ](https://www.expedia.com/Budget-Car-Rentals-In-Florence-Regional.d6027805-c39.Car-Rental-Guide-Suppliers)