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Our top choices for Santa María hotels

One Oaxaca Centro Hotel

One Oaxaca Centro Hotel
3.0 star property
Ruta Independencia, 1.5 mi from Santa María
8.8 out of 10, Excellent, (1003)
"Very good hotel"
United States
Hugo
$76 nightly
The price is $92
Dec 13 - Dec 14
Total with taxes and fees
One Oaxaca Centro Hotel

Quinta Real Oaxaca

Quinta Real Oaxaca
4.5 star property
Ruta Independencia, 1.2 mi from Santa María
9.6 out of 10, Exceptional, (1000)
"We loved everything about our stay at Quinta Real in Oaxaca, highly recommend, would definitely stay again!"
United States
Valerie
$269 nightly
The price is $320
Dec 16 - Dec 17
Total with taxes and fees
Quinta Real Oaxaca

Capital O Posada La Casa De La Tia, Oaxaca

Capital O Posada La Casa De La Tia, Oaxaca
3.0 star property
Ruta Independencia, 1.2 mi from Santa María
7.8 out of 10, Good, (195)
"You can walk around downtown "
United States
GORGONIO
$49 nightly
The price is $58
Jan 8 - Jan 9, 2026
Total with taxes and fees
Capital O Posada La Casa De La Tia, Oaxaca

Hotel Hacienda

Hotel Hacienda
3.5 star property
1.9 mi from Santa María
9.0 out of 10, Wonderful, (1006)
"Super friendly and helpful staff, clean room and very good food at the restaurant!!!"
Mexico
Carlos
$56 nightly
The price is $67
Dec 12 - Dec 13
Total with taxes and fees
Hotel Hacienda

LePetit

LePetit
2.5 star property
Ruta Independencia, 1.4 mi from Santa María
9.4 out of 10, Exceptional, (21)
"The staff is amazing"
United States
Carmen
$106 nightly
The price is $126
Dec 16 - Dec 17
Total with taxes and fees
LePetit

Happy Express Hotel

Happy Express Hotel
2.5 star property
Oaxaca Centro, 1.1 mi from Santa María
9.0 out of 10, Wonderful, (319)
"Nice and clean close to everything easy walking Quiet, comfortable bed and pillows "
United States
MIRIAM
Happy Express Hotel

Hotel Victoria Oaxaca

Hotel Victoria Oaxaca
3.5 star property
0.5 mi from Santa María
8.8 out of 10, Excellent, (1000)
"Good breakfast at the restaurant. Nice setting. Friendly front desk staff."
Canada
David
$59 nightly
The price is $70
Jan 9 - Jan 10, 2026
Total with taxes and fees
Hotel Victoria Oaxaca

Casa de los Frailes Hotel

Casa de los Frailes Hotel
3.0 star property
Ruta Independencia, 1.2 mi from Santa María
9.2 out of 10, Wonderful, (363)
"Good location close to the centre but on a fairly quiet street. Large rooms, decent shower. "
United Kingdom
Richard
$72 nightly
The price is $85
Dec 14 - Dec 15
Total with taxes and fees
Casa de los Frailes Hotel

Grand Fiesta Americana Oaxaca

Grand Fiesta Americana Oaxaca
5.0 star property
Ruta Independencia, 1.3 mi from Santa María
9.6 out of 10, Exceptional, (665)
"Great staff, beautiful rooms, wonderful food. Also perfect location."
United States
John Lester
$191 nightly
The price is $233
Dec 17 - Dec 18
Total with taxes and fees
Grand Fiesta Americana Oaxaca

Casa Los Cantaros Hotel Boutique

Casa Los Cantaros Hotel Boutique
3.5 star property
Reforma, 1.1 mi from Santa María
9.4 out of 10, Exceptional, (265)
"Nice staff and huge room with all the amenities."
United States
Celia
$73 nightly
The price is $87
Dec 16 - Dec 17
Total with taxes and fees
Casa Los Cantaros Hotel Boutique

Casa De Sierra Azul

Casa De Sierra Azul
3.5 star property
Oaxaca Centro, 1.4 mi from Santa María
9.2 out of 10, Wonderful, (898)
"Hospitality was the best. Great location with a lot of shops and Zocalo at walkable distance. rooms were beautiful and comfortable "
United States
Brian
$144 nightly
The price is $172
Dec 16 - Dec 17
Total with taxes and fees
Casa De Sierra Azul

Marqués Oaxaca - Hotel

Marqués Oaxaca - Hotel
2.0 star property
1.5 mi from Santa María
7.2 out of 10, Good, (106)
"Staff was friendly, & helpful. The location was perfect! Everything was in walking distance, but if you needed a cab the hotel gladly arranged one for you. "
United States
Daisy
$22 nightly
The price is $26
Dec 14 - Dec 15
Total with taxes and fees
Marqués Oaxaca - Hotel

Hotel Boutique Parador San Miguel

Hotel Boutique Parador San Miguel
3.0 star property
Ruta Independencia, 1.1 mi from Santa María
9.4 out of 10, Exceptional, (777)
"Was one of the best hotels, clean the people were awesome and helped whenever needed"
United States
Asokaraj
$130 nightly
The price is $154
Jan 10 - Jan 11, 2026
Total with taxes and fees
Hotel Boutique Parador San Miguel

Hotel Trebol

Hotel Trebol
3.0 star property
Oaxaca Centro, 1.3 mi from Santa María
9.2 out of 10, Wonderful, (1008)
"Amazing staff and accommodations will be coming back"
United States
Christopher Joel Romo
$96 nightly
The price is $114
Dec 13 - Dec 14
Total with taxes and fees
Hotel Trebol

Hotel Danibaan

Hotel Danibaan
3.0 star property
Del Ex-marquezado, 0.7 mi from Santa María
9.4 out of 10, Exceptional, (169)
"Clean Gustavo and staff were very nice and i slept so well. It felt like home away from home. "
United States
Marisol
$40 nightly
The price is $48
Dec 12 - Dec 13
Total with taxes and fees
Hotel Danibaan

Hotel Boutique Naura Centro

Hotel Boutique Naura Centro
3.5 star property
Oaxaca Centro, 1.3 mi from Santa María
9.2 out of 10, Wonderful, (978)
"wonderful staff and great amenities. Delicious food in their restaurant + cafe."
United States
Edna
$117 nightly
The price is $139
Dec 18 - Dec 19
Total with taxes and fees
Hotel Boutique Naura Centro

HOTEL POSADA DON MATIAS

HOTEL POSADA DON MATIAS
2.0 star property
Oaxaca Centro, 1.3 mi from Santa María
9.0 out of 10, Wonderful, (193)
"It was a quiet place."
United States
Consuelo
$26 nightly
The price is $31
Dec 13 - Dec 14
Total with taxes and fees
HOTEL POSADA DON MATIAS

Casa Antonieta

Casa Antonieta
3.5 star property
Oaxaca Centro, 1.3 mi from Santa María
10.0 out of 10, Exceptional, (59)
"A lovely spot all around. "
Canada
Kelly
$363 nightly
The price is $432
Jan 7 - Jan 8, 2026
Total with taxes and fees
Casa Antonieta

Hotel Real Alma

Hotel Real Alma
3.5 star property
Oaxaca Centro, 1.1 mi from Santa María
9.0 out of 10, Wonderful, (406)
"Cozy and comfortable hotel. Very clean and staff was very nice and friendly ready to help you with any questions."
United States
Julia
$62 nightly
The price is $74
Dec 12 - Dec 13
Total with taxes and fees
Hotel Real Alma

Casa de Adobe Gallery & Luxury Boutique

Casa de Adobe Gallery & Luxury Boutique
4.0 star property
San Felipe del Agua, 2 mi from Santa María
9.0 out of 10, Wonderful, (177)
"Hotel was very clean, great food, and very friendly staff! "
United States
ANGELICA
$138 nightly
The price is $165
Dec 16 - Dec 17
Total with taxes and fees
Casa de Adobe Gallery & Luxury Boutique
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santa María

Find the best Santa María areas and neighborhoods for the activities you enjoy most.

Oaxaca Centro

Discover colonial-era structures and immerse in native Zapotec and Mixtec cultures in this UNESCO World Heritage Site. Explore the archeological marvel of Monte Albán and admire the unique green stone architecture.

Ruta Independencia

If you're spending some time in Ruta Independencia, Oaxaca Ethnobotanical Garden and Jardín Etnobotánico are top sights worth seeing.

Jalatlaco

While Jalatlaco isn't home to many top sights, El Llano Park and Oaxaca Ethnobotanical Garden are some notable places to visit nearby.

Reforma

If you're spending some time in Reforma, Plaza Mazari and Plaza Parque are top sights worth seeing.

San Agustín Yatareni

While there might not be top attractions in San Agustín Yatareni, you can explore the larger area and discover places like El Llano Park and Oaxaca Ethnobotanical Garden.

Top Santa María Hotel Reviews

Frequently asked questions

What are the best hotels in Santa María that travelers recommend?
For hotels in Santa María that travelers highly recommend, consider the Grand Fiesta Americana Oaxaca, Quinta Real Oaxaca, Hotel Azul Oaxaca, Hotel Sin Nombre, and Hotel De La Parra.

The 5-star Grand Fiesta Americana Oaxaca, with an excellent 9.6 rating, offers a luxurious stay with amenities like a poolside bar, rainfall showerheads, and deep soaking bathtubs. Guests consistently praise the excellent and attentive staff, as well as the great food and location. It is conveniently located near El Llano Park, just 0.0 miles away, and the Museo de las Culturas de Oaxaca, 0.3 miles away.

Another exceptional option is the 4.5-star Quinta Real Oaxaca, also rated 9.6. This hotel features premium bedding, air conditioning, and 24-hour room service. Travelers frequently praise the friendly and helpful staff, the comfortable and super clean rooms, and the excellent and superb location. The hotel is 0.2 miles from the Museo de las Culturas de Oaxaca and 0.4 miles from El Llano Park.

Hotel Azul Oaxaca, with a 9.2 rating, provides comfortable suites with amenities such as bathrobes, rainfall showerheads, and Egyptian cotton sheets. Guests consistently highlight the excellent and fantastic location, along with the friendly and helpful staff and excellent service. It is located 0.2 miles from the Museo de las Culturas de Oaxaca and 0.3 miles from El Llano Park.

The 4-star Hotel Sin Nombre, rated 8.6, offers unique features like couples dining and champagne service, along with a poolside bar. Travelers appreciate the comfortable and clean rooms, the excellent and friendly staff, and the great amenities. It is 0.2 miles from Mercado 20 de Noviembre and 0.5 miles from the Museo de las Culturas de Oaxaca.

Lastly, the 4-star Hotel De La Parra, with a 9.2 rating, provides air conditioning, rainfall showerheads, and a poolside bar. Guests frequently mention the friendly staff who are always willing to help, the comfortable and beautiful rooms, and the superb and great location. The hotel is ideally situated 0.1 miles from Zócalo and 0.2 miles from Mercado 20 de Noviembre.
What are the best family hotels in Santa María?
For families traveling to Santa María, excellent hotel options include the Grand Fiesta Americana Oaxaca, Casa De Sierra Azul, and Hotel De La Parra.

The 5-star Grand Fiesta Americana Oaxaca, with an outstanding 9.6 rating, offers a refreshing pool and complimentary cribs and rollaway beds, making it ideal for families. Children also stay free with an adult. It is conveniently located very close to El Llano Park and just 0.3 miles from the Museo de las Culturas de Oaxaca. Guests consistently praise the excellent and attentive staff, as well as the great food.

Another highly-rated choice is the 3.5-star Casa De Sierra Azul, boasting a 9.2 rating. This hotel provides child-friendly window design, complimentary cribs, and onsite babysitting services, ensuring a comfortable stay for families. Its location is perfect, being only 0.2 miles from Zócalo and La Paz Museum, and 0.3 miles from Mercado 20 de Noviembre. Guests frequently highlight the helpful staff, spacious rooms, and beautiful courtyard.

The 4-star Hotel De La Parra, also with a 9.2 rating, is another great option. It features onsite babysitting and complimentary cribs for young guests. This hotel is perfectly situated just 0.1 miles from Zócalo and 0.2 miles from Mercado 20 de Noviembre and La Paz Museum. Travelers appreciate the friendly staff, comfortable rooms, and excellent customer service.
What are the best 5-star hotels in Santa María?
For a superb 5-star hotel in Santa María, consider the Grand Fiesta Americana Oaxaca.

This exceptional hotel, with a 9.6 rating, offers a luxurious experience with amenities such as a poolside bar, 24-hour room service, and premium bedding for ultimate comfort. Guests frequently praise the excellent and attentive staff, the amazing and friendly service, and the great food. It is conveniently located near El Llano Park, just 0.3 miles from Museo de las Culturas de Oaxaca, and 0.5 miles from Macedonio Alcalá Theater, making it ideal for exploring the city's cultural attractions.
What are the best spa hotels in Santa María?
For an exceptional spa experience in Santa María, consider the Grand Fiesta Americana Oaxaca, NaNa Vida Hotel Oaxaca, or Hotel Sin Nombre.

The 5-star Grand Fiesta Americana Oaxaca, with an outstanding 9.6 rating, offers a full-service spa with a wide array of treatments including facial treatments, deep tissue massage, hot stone massage, and hydrotherapy treatments. Guests frequently praise the excellent and attentive staff, as well as the great food. It is conveniently located just 0.5 miles from the Macedonio Alcalá Theater.

Another excellent option is the NaNa Vida Hotel Oaxaca, a 3.5-star hotel with a remarkable 9.8 rating. Its full-service spa provides deep tissue massage, aromatherapy treatments, hot stone massage, and Ayurvedic treatments. Travelers often mention the attentive staff, comfortable and clean rooms, and its superb location just 0.2 miles from the Macedonio Alcalá Theater.

The 4-star Hotel Sin Nombre, rated 8.6, also features an on-site spa with various massage options including sports massage, Swedish massage, and deep tissue massage. Guests appreciate the comfortable and clean rooms, excellent and friendly staff, and the tasty breakfast. It is situated just 0.2 miles from the Macedonio Alcalá Theater.
What hotels in Santa María offer free breakfast?
For hotels in Santa María that offer complimentary breakfast, consider El Callejón Hotel Boutique, Hotel Ayook, Hotel Parador de Alcalá Oaxaca, Hotel con Corazón Oaxaca, and Holiday Inn Express Oaxaca-Centro Historico by IHG.

The 4-star El Callejón Hotel Boutique, with a superb 10.0 rating, provides both free continental and regular breakfast. Guests frequently praise the excellent and friendly staff, as well as the beautiful location. It's conveniently located near the Church of Santo Domingo de Guzmán and the Museum of Oaxacan Culture, both within 0.4 miles.

Hotel Ayook, a 3.5-star hotel rated 9.8, offers complimentary breakfast, including cooked options. Visitors often highlight the excellent breakfast and great service. The hotel features a rooftop terrace and is situated about 0.6 miles from the Church of Santo Domingo de Guzmán.

Another excellent option is the 3.5-star Hotel Parador de Alcalá Oaxaca, which has a 9.6 rating. This hotel provides free full breakfast and a 24-hour airport shuttle. It is very close to the Church of Santo Domingo de Guzmán, just 0.1 miles away, and guests appreciate the comfortable and clean rooms.

Hotel con Corazón Oaxaca, with a 9.6 rating, offers free local breakfast and a 24-hour airport shuttle. Travelers frequently praise the delicious breakfast and the friendly staff. It is located approximately 0.6 miles from the Church of Santo Domingo de Guzmán.

The 3-star Holiday Inn Express Oaxaca-Centro Historico by IHG, rated 9.4, also includes free breakfast, with full breakfast options available. Guests often mention the great location and the friendly staff. The hotel is about 0.3 miles from the Church of Santo Domingo de Guzmán and 0.3 miles from the Museum of Oaxacan Culture.
What are the top pet-friendly hotels in Santa María?
For top pet-friendly hotels in Santa María, consider the Grand Fiesta Americana Oaxaca, Casa De Sierra Azul, Viajero Oaxaca Hostel, Selina Oaxaca, or Hotel Boutique Naura Centro.

The 5-star Grand Fiesta Americana Oaxaca, with an outstanding 9.6 rating, warmly welcomes dogs and provides amenities such as food and water bowls. Guests consistently praise the excellent and attentive staff, great location, and friendly service. It is conveniently located near El Llano Park and just 0.3 miles from the Museo de las Culturas de Oaxaca.

Another excellent option is the 3.5-star Casa De Sierra Azul, rated 9.2. This hotel permits both dogs and cats and offers food and water bowls. Travelers frequently highlight the helpful and amazing staff, spacious and clean rooms, and great location. It is situated 0.2 miles from La Paz Museum and Zócalo.

The Viajero Oaxaca Hostel, with a 9.4 rating, is a pet-friendly choice that welcomes both dogs and cats. It is located 0.4 miles from the Museo de las Culturas de Oaxaca.

Selina Oaxaca, rated 8.2, is another pet-friendly accommodation for both dogs and cats. Guests often mention that the rooms are always clean. It is conveniently located 0.2 miles from the Museo de las Culturas de Oaxaca.

Finally, the 3.5-star Hotel Boutique Naura Centro, with a 9.2 rating, also permits pets. Guests appreciate the friendly and helpful staff, comfortable and clean rooms, and excellent location. It offers free and easy parking and is located 0.2 miles from La Paz Museum and Zócalo.
What are the top boutique hotels in Santa María?
For top boutique hotels in Santa María, consider Hotel Los Amantes and Hotel Marques del Valle.

The 3-star Hotel Los Amantes, with an 8.4 rating, offers complimentary continental breakfast and free toiletries, along with a convenient 24-hour airport shuttle. Guests often praise the delicious breakfast and the great location, just 0.3 miles from Macedonio Alcalá Theater.

Another excellent option is the 3-star Hotel Marques del Valle, rated 8.6. This hotel provides free self-parking and free WiFi, and is ideally situated just 0.1 miles from Macedonio Alcalá Theater. Travelers frequently highlight the perfect, great location, the extremely helpful and wonderful staff, the comfortable rooms, and the exceptional service.
What are the best budget hotels in Santa María?
For excellent budget-friendly accommodations in Santa María, consider the Hotel Trebol, Pug Seal Oaxaca, Sauvé Casa Boutique, City Express by Marriott Oaxaca, and Hotel Los Amantes.

The 3-star Hotel Trebol, with a 9.2 rating, offers a convenient 24-hour airport shuttle and complimentary breakfast, including English breakfast options. Guests consistently praise the friendly and helpful staff, the delicious free breakfast, and the clean rooms. Its location is also highly regarded, being just 0.1 miles from the Government Palace and 0.2 miles from Museo Textil de Oaxaca and Macedonio Alcalá Theater.

Another outstanding option is the 3-star Pug Seal Oaxaca, which boasts an impressive 9.6 rating. This hotel provides a 24-hour airport shuttle, free full breakfast, and complimentary stocked minibar items. Guests frequently praise its superb location, being only 0.2 miles from the Church of Santo Domingo de Guzmán and Government Palace, and 0.3 miles from Museo Textil de Oaxaca and Museum of Oaxacan Culture. The staff also receives high praise for being great and amazing.

The 3-star Sauvé Casa Boutique, rated 9.6, is known for its friendly and attentive staff and comfortable rooms. It offers a 24-hour airport shuttle and a free English breakfast. The hotel's excellent location places it just 0.2 miles from the Church of Santo Domingo de Guzmán, Museo Textil de Oaxaca, Macedonio Alcalá Theater, and Museum of Oaxacan Culture.

The 3-star City Express by Marriott Oaxaca, with an 8.6 rating, offers free WiFi, free buffet breakfast, and a complimentary area shuttle. Guests frequently mention the good breakfast and great staff. It is conveniently located 0.5 miles from the Church of Santo Domingo de Guzmán and Museum of Oaxacan Culture, and 0.8 miles from Museo Textil de Oaxaca and Macedonio Alcalá Theater.

Finally, the 3-star Hotel Los Amantes, rated 8.4, provides a 24-hour airport shuttle and free continental breakfast. Guests appreciate the delicious breakfast and superb location, being only 0.1 miles from the Church of Santo Domingo de Guzmán and Museum of Oaxacan Culture.
What are the most romantic hotels in Santa María for couples?
For a romantic stay in Santa María, consider the Grand Fiesta Americana Oaxaca or SPIRA HOTEL.

The 5-star Grand Fiesta Americana Oaxaca, with a 9.6 rating, offers a luxurious spa experience superb for couples, including a hot tub, couples treatment rooms, and a full range of massage and body treatments. The hotel is conveniently located just half a mile from the Macedonio Alcalá Theater. Guests frequently praise the excellent and attentive staff and the great food.

The 3-star SPIRA HOTEL, boasting an exceptional 9.8 rating, provides a more intimate setting with private outdoor hot tubs and furnished balconies, ideal for romantic evenings. It is situated just 0.4 miles from the Macedonio Alcalá Theater. Travelers often highlight the beautiful and clean rooms, as well as the friendly and helpful staff.
What are the best hotels in Santa María near Zócalo?
For hotels in Santa María near Zócalo, consider the Hotel Trebol or Hotel Boutique Naura Centro.

The 3-star Hotel Trebol, with a rating of 9.2, is an excellent option as it is located just 0.1 miles from Zócalo. Guests appreciate the complimentary English breakfast and the convenience of a 24-hour airport shuttle.

Another great choice is the 3.5-star Hotel Boutique Naura Centro, rated 9.2, which is situated only 0.2 miles from Zócalo. This hotel offers amenities such as a travel crib and free cribs, along with on-site babysitting and childcare services, making it a good fit for families.
When is the best time to go to Santa María?
The best time to visit Santa María, Oaxaca, Mexico, is during the dry season, which runs from October to May, with November through February being particularly pleasant.

During these months, you'll experience comfortable temperatures, typically ranging from the low 70s to mid-80s Fahrenheit (20s to low 30s Celsius), and significantly less rainfall. This makes it ideal for exploring the town and surrounding natural attractions without the interruption of daily downpours.

Couples looking for a relaxing escape will appreciate the consistently sunny days, great for enjoying outdoor activities like visiting the Árbol del Tule or exploring local artisan markets. The cooler evenings also make for comfortable dining experiences.

Solo travelers will find the dry season excellent for navigating the area, whether it's for hiking in the nearby mountains or taking part in cultural tours.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Santa María.
How can I save on a Santa María hotel booking with Expedia?
One Key™ - Expedia's free travel rewards program - gives you instant access to perks and Member Prices on Santa María hotels. Plus, you'll earn OneKeyCash™* on eligible bookings to use on future trips. Booking an Expedia hotel and flight package is another great way to save, where bundling can result in significant savings.

*OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
How much is the nightly rate at a Santa María hotel?
Prices for hotels in Santa María often vary, but you can find a great deal on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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