Find Resorts & Hotels with Spas in St. Charles, MO

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Pick from 29 St. Charles Resorts & Hotels with Spas and compare room rates, reviews, and availability. Most hotels are fully refundable.

Exterior
1790's Renovated Barn, Main Street St. Charles, Hot Tub in private backyard!
10.0 out of 10, Exceptional, (185)
"We had a great time! The Red Barn was just what we needed for some quiet time to relax and take our time in St. Charles. The location is the perfect distance from the main street so you don't have to walk far to find something to do, but it's also not right on the "main drag" where you'd have people walking by all the time. Thanks for the hospitality!"
1790's Renovated Barn, Main Street St. Charles, Hot Tub in private backyard!
Exterior
1870's Luxury Guest Cottage, Historic Downtown St. Charles, Mo.
10.0 out of 10, Exceptional, (238)
"We loved theguesthouse it was such a nice place and clise to everything"
1870's Luxury Guest Cottage, Historic Downtown St. Charles, Mo.
Property grounds
Walk to St Charles Main St. Shops, Eateries & Bars! Bubble Tent!
10.0 out of 10, Exceptional, (48)
"We enjoyed our stay at the Lion House! The hosts are amazing! It was a great location, close to the airport, and an easy walk to downtown St. Charles. We also walked to Lindenwood U. one day, a little further but still doable. We enjoyed exploring the St. Charles and Frenchtown areas and the Katy Trail. The house was well appointed with many amenities, it was spotless on arrival and as described! We enjoyed morning coffee and evening conversations in the covered sitting area out back. Having two...
Walk to St Charles Main St. Shops, Eateries & Bars! Bubble Tent!
Property grounds
Charming Cottage on Main St. in Historic St. Charles! Jetted Tub, 2 Fireplaces!!
10.0 out of 10, Exceptional, (219)
"The property was very clean and a perfect location. We will definitely stay there again."
Charming Cottage on Main St. in Historic St. Charles! Jetted Tub, 2 Fireplaces!!
Exterior
Luxurious couples retreat just steps from Historic Main Street in St. Charles!
10.0 out of 10, Exceptional, (67)
"My husband and I went for a short weekend trip and had the best time. Property was spotless and comfortable. Beds were comfy. House was well stocked. Made it easy to relax! Not even a block from all the shops. We will absolutely stay again!"
Luxurious couples retreat just steps from Historic Main Street in St. Charles!
Lobby
Drury Plaza Hotel St. Louis St. Charles
3.0 star property
9.8 out of 10, Exceptional, (1000)
"Love the environment. Great customer service and very polite staff. Enjoyed my stay for the second time and will def be going back. "
The price is $139
$159 total
includes taxes & fees
Jun 2 - Jun 3
Drury Plaza Hotel St. Louis St. Charles
Fridge, microwave, oven, stovetop
St. Charles 1860's Gem - Sleeps 6!
9.8 out of 10, Exceptional, (69)
"Older property in walking distance of shopping, restaurants, and the Katy trail and small parks. Plenty of towels, comfy bed, and good lighting. Parking in back a plus. Friendly neighbors. Dogs welcome, bring all dog supplies. New door mats will be a plus."
St. Charles 1860's Gem - Sleeps 6!
Smart TV
Residence on the Roundabout
9.6 out of 10, Exceptional, (104)
"Very nice rental! Location is good and the property is just as described. Clean and well maintained! Excellent communication from the host!"
Residence on the Roundabout
Interior
Charming open 4bd and screen-in porch! Sleeps 10!
9.0 out of 10, Wonderful, (18)
"This property was quaint, spacious, comfortable, and in a very safe & quiet neighborhood. I would recommend this home and will book again."
The price is $183
$417 total
includes taxes & fees
May 22 - May 23
Charming open 4bd and screen-in porch! Sleeps 10!
Fridge, microwave, oven, stovetop
St. Charles, MO house with Private Patio
9.0 out of 10, Wonderful, (13)
"Really appealing, quaint property 15 mins easy walk from Main Street. Lots of character- antique furniture, squeaky floors and a scary basement! Be aware that the bathroom is downstairs so you may need to navigate steep stairs at night. There is also not a dishwasher. (Hence not a 5 star review) Nice little patio and lovely neighbourhood. Overall, very much enjoyed our stay"
St. Charles, MO house with Private Patio
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

St. Charles Resorts & Hotels with Spas information

 

Resorts & Hotels with Spas in St. Charles

29

Highest price
$169
Cheapest price
$76
Number of guest reviews
4,503
Total number of hotels in St. Charles
2,494

 

Frequently asked questions

Looking for a spa hotel in St. Charles?
Book one of our lush spa hotels and pamper yourself from the moment you arrive. Travelers highly recommend the restaurants in St. Charles. Enjoy the historical sites and riverfront during your vacation. Hotels with spas are a great way to break away from your daily routine and add a layer of luxury to your vacation.
What is the best spa hotel in St. Charles?
Ameristar Casino Resort and Spa is a top luxury spa hotel featuring 5 restaurants, a casino, a pool, and a 24-hour fitness center. Treat yourself to a facial, body scrub, or hydrotherapy at Ara.
How many spa hotels will I find in St. Charles?
Among Expedia’s 168 accommodation options in St. Charles, there is 1 spa hotel.
What's there to see and do in St. Charles?
Experience all that St. Charles has to offer when you visit Historic Main Street, Katy Trail, and St Charles Convention Center. If you have some spare time during your trip, you might want to check out Ameristar Casino St. Charles and Fast Lane Classic Cars.
What is a St. Charles spa hotel?
Spa hotels in St. Charles provide lodging and have an on-site spa which offers services like couples massages as well as body treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on vacation.

Recent reviews of St. Charles hotels
Expedia verified reviews

Moonrise Hotel

Moonrise Hotel

5/5 Excellent
"Wonderful room and great rooftop bar with fantastic views of the city!"
A verified traveler stayed at Moonrise Hotel
Posted 1 day ago
Moonrise Hotel