$588 Cheap Flights from Santo Domingo (SDQ) to Uyuni (UYU)

View $588 flight on Thu, Aug 28, 2025Opens in a new window

Popular airlines from Las Americas Intl. Airport (SDQ) to Uyuni (UYU)

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Cheap Flights from Santo Domingo to Uyuni (SDQ-UYU)

Prices were available within the past 7 days and start at $588 for one-way flights and for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Flights from Santo Domingo (SDQ) to Uyuni (UYU)
Origin airport
Las Americas Intl.
Destination airport
Uyuni
Distance
2692 mi

Santo Domingo to Uyuni Flights

The cheapest times to fly from Santo Domingo to Uyuni

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Santo Domingo to Uyuni are during the month of . You can find some of the cheapest flights from Santo Domingo to Uyuni with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Santo Domingo to Uyuni

Sunday is one of the best days to book for cheap flights from Santo Domingo to Uyuni: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Santo Domingo to Uyuni

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Santo Domingo to Uyuni in 2025. You can also book with separate airlines for your outbound and return journeys, from $588 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Santo Domingo to Uyuni flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Santo Domingo to Uyuni airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Las Americas Intl. Airport (SDQ) to Uyuni Airport (UYU) cost?
Get a cheap one-way flight from $588 or cheap return flight from Las Americas Intl. Airport (SDQ) to Uyuni Airport (UYU) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Las Americas Intl. Airport (SDQ) to Uyuni Airport (UYU)?
Planning your trip for can help you save, as it's the cheapest month for flights between SDQ and UYU. You'll usually find the lowest fares during off-peak months.
What is the cheapest airline that flies from Las Americas Intl. Airport (SDQ) to Uyuni Airport (UYU)?
Expedia's filter tool lets you easily compare different airlines, flight durations and fares all in one place. Customize the search to your preferences, then sort by "Price (lowest to highest)" to find the carrier with the cheapest SDQ to UYU flight.
How many flights per day from Las Americas Intl. Airport (SDQ) to Uyuni Airport (UYU)?
There aren't any daily direct flights departing from Las Americas Intl. Airport (SDQ) to Uyuni Airport (UYU). But you can opt for flights with layovers. Filter your search results on Expedia to include one or two stops, and you'll be cruising above the clouds before you know it.
What day of the week has the most flights from SDQ to UYU?
Generally you'll find the greatest selection of flight options on a Friday. Tuesdays tend to be the quietest.* However, this can change based on the season, airline and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Las Americas Intl. Airport (SDQ) to Uyuni Airport (UYU)?
Opt for a flight from Las Americas Intl. Airport (SDQ) to Uyuni Airport (UYU) that leaves before 3 PM to reduce the risk of delays and cancellations. Departures after this time are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Las Americas Intl. Airport (SDQ) to Uyuni Airport (UYU) last-minute?
Waiting until right before your break to book a flight from SDQ to UYU often results in higher prices. While it's possible to find some last-minute discounts, they aren't always guaranteed. Keep your travel plans flexible to maximize your chances of snagging a bargain.
Is it cheaper to book a SDQ to UYU flight and hotel package?
Compared with arranging hotels and flights separately, booking a SDQ to UYU flight and hotel package with Expedia could result in significant savings. Better yet, having everything in one easy place will take the stress out of planning your trip. Simply pick your flights and select from our wide range of stays, then tailor your trip with other add-ons like activities, tours and car rentals.
Can I cancel or change the date of my flight from Las Americas Intl. Airport (SDQ) to Uyuni Airport (UYU)?
If you reserved your SDQ to UYU flight in the last 24 hours, you may be able to modify or cancel it at no cost. Depending on the airline and the type of fare you purchased, additional charges may apply for changes beyond that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, go to our Customer Service portal for further details.

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