$80 Cheap American Airlines flights Las Vegas (LAS) to San Diego (SAN)

Landing cheap one-way American Airlines flights from LAS to SAN from $80 on Expedia is simple — just filter by “Price (lowest to highest).” Or check out our affordable round-trip fares from $159 for your next exciting getaway.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

American Airlines flights to San Diego tend to be cheaper in the off-peak months of January and November. Whether you need a round-trip or one-way ticket, you could score a better deal then.

For cheap American Airlines fares from Harry Reid Intl. Airport (LAS) to San Diego Intl. Airport (SAN), start searching one to three months before your planned departure. Reserving domestic flights 34 to 86 days in advance could save you 25% compared to booking just 6 to 12 days ahead. The day you book can also impact what you pay. Sunday is typically the cheapest, while Monday is often the most expensive for domestic flights. You can save 6% on average by booking your flight on a Sunday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC’s global airline sales database.

Select our “Nonstop” filter when searching for direct American Airlines flights from LAS to SAN. It’s also a great way to compare other carriers servicing the same nonstop trip.

To find the earliest departure from LAS to SAN with American Airlines, filter your results by “Early Morning” and “Morning.” Choosing an early flight generally means you’ll experience fewer cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.

San Diego Intl. Airport (SAN) is the primary San Diego gateway for American Airlines flights from Harry Reid Intl. Airport (LAS).

You can usually cancel or change your flight, although there may be additional charges if you made your booking more than 24 hours ago. Want to keep your options open? Make use of Expedia’s “No cancel fee” or “Changes included” filter to find flights that won’t charge you extra if you need to adjust your plans. To modify your booking, go to “Trips,” select your flight and click on “Manage Booking” for further information.