$137 Cheap American Airlines flights Miami (MIA) to Santiago (STI)

Finding cheap one-way American Airlines flights from MIA to STI from $137 on Expedia couldn't be simpler — just filter by "Price (lowest to highest)." Alternatively, check out our affordable round-trip fares from $243 for your next break.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Start your search for American Airlines flights from MIA to STI about one month before you want to go. The cheapest time to book an international flight is generally 18 to 29 days ahead of your departure date when you can save 17% versus booking four to five months in advance. Regardless of itinerary or fare class, the best day to book international airfare is usually Sunday. Friday can be the most expensive. Travelers booking on a Sunday can save 17% on average compared to those who book on a Friday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

The first flight from MIA to STI with American Airlines leaves at 11:25AM UTC-5. You'll land at 2:20PM UTC-4. The last American Airlines flight of the day leaves at 11:25AM UTC-5 and arrives at 2:20PM UTC-4. With 20% fewer cancellations for early and mid-morning departures, setting off early is often the best choice.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.