$144 Cheap American Airlines flights Missoula (MSO) to San Diego (SAN)

You’ll find affordable round-trip American Airlines flights from $246 from MSO to SAN by organizing your results from “Price (lowest to highest)” on Expedia. Or look for options from $144 for a one-way journey.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Browse for return or one-way flights to San Diego in January or November. You could find cheaper fares with American Airlines during these off-season months.

Look for cheap American Airlines flights from Missoula Intl. Airport (MSO) to San Diego Intl. Airport (SAN) one to three months before your day of departure. Travelers who book domestic flights 34 to 86 days in advance can save 25% compared to those who book just 6 to 12 days ahead. Regardless of fare class and journey, the ideal day to book a domestic flight is usually Sunday and the most expensive is typically Monday. Passengers who book on a Sunday can save 6% on average compared to those who book on a Monday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC’s global airline sales database.

To see if there’s a direct trip from MSO to SAN with American Airlines or another carrier, check the “Nonstop” filter when searching for flights.

Browse American Airlines’s earliest flights from MSO to SAN by selecting our “Early Morning” and “Morning” filters. Not only will you arrive at your destination sooner, early departures are also 20% less likely to be canceled.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.

Hop on an American Airlines flight from Missoula Intl. Airport (MSO) to San Diego, and you’re most likely to touch down at San Diego Intl. Airport (SAN). This is the airline’s primary hub in this destination.

Changes are typically free within 24 hours of making your booking, but your airline may add a charge after that. For further information about altering your reservation, head to your “Trips,” select your flight and click on “Manage Booking.” If you’d like the freedom to make changes without being charged, apply the “Changes included” or “No cancel fee” filter when planning your next escape.