$115 Cheap American Airlines flights Moline (MLI) to San Diego (SAN)

You’ll discover budget-friendly return American Airlines flights from $229 from MLI to SAN by organizing your results from “Price (lowest to highest)” on Expedia. Or search for options from $115 for a one-way journey.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

American Airlines flights to San Diego are often more affordable in the quieter months of January and November. Whether you’re after a return or one-way ticket, you could find a better deal then.

Start searching one to three months before your departure to get cheap fares on American Airlines flights from Quad City Intl. Airport (MLI) to San Diego Intl. Airport (SAN). You can save 25% by booking your domestic flight 34 to 86 days in advance versus last-minute reservations made 6 to 12 days out. You could also cut costs by buying your fare on a Sunday, as it’s 6% cheaper on average than a Monday, the most expensive day to book.* Get the timing right, and you can enjoy significant savings on domestic trips.*Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC’s global airline sales database.

To find out if there’s a direct journey from MLI to SAN with American Airlines or another carrier, use our “Nonstop” filter when browsing for flights.

Search American Airlines’s earliest flights from MLI to SAN by using the “Early Morning” and “Morning” filters. Not only will you get to your destination sooner, early departures also experience 20% fewer cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.

San Diego Intl. Airport (SAN) is the primary San Diego gateway for American Airlines flights from Quad City Intl. Airport (MLI).

Changes are typically free within 24 hours of making your booking, but your airline may charge a fee after that. For further information about modifying your flights, check out your “Trips,” select your flight and click on “Manage Booking.” If you’d like the freedom to adjust your plans without additional costs, tick the “No cancel fee” or “Changes included” filter when organizing your next break.