$109 Cheap Delta flights St. Louis (STL) to Columbia (CAE)

Apply the "Price (lowest to highest)" filter on Expedia to look for cheap Delta Air Lines return flights from $217 from STL to CAE. Affordable one-way options from $109 are available too.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Search for affordable Delta Air Lines flights from Lambert-St. Louis Intl. Airport (STL) to Columbia Metropolitan Airport (CAE) one to three months prior to your departure date. Travelers who book domestic flights 34 to 86 days in advance can save 25% compared to those who book just 6 to 12 days ahead. No matter the fare class and itinerary, the best day of the week to book a domestic flight is usually Sunday and the most expensive is typically Monday. Passengers who book on a Sunday can save 6% on average compared to those who book their travel on a Monday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

Find Delta Air Lines's earliest flights from STL to CAE by checking our "Morning" and "Early Morning" filters. Not only will you arrive sooner, early departures also experience 20% fewer cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.

With a rewarding loyalty program and an excellent in-flight experience, Delta Air Lines is a top choice for many passengers flying from STL to CAE. What's more, if you're a Delta SkyMiles and One Key™ member booking through Expedia, you could earn OneKeyCash™* on eligible flights on top of your airline miles, which can be spent on future travel.*OneKeyCash™ disclaimer - OneKeyCash™ is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.