$159 Cheap Delta flights Seattle (SEA) to Des Moines (DSM)

Use the "Price (lowest to highest)" filter on Expedia to find cheap Delta Air Lines return flights from $311 from SEA to DSM. Affordable one-way tickets from $159 are also available.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Start searching one to three months ahead of your departure date to score cheap fares on Delta Air Lines flights from Seattle - Tacoma Intl. Airport (SEA) to Des Moines Intl. Airport (DSM). You can save 25% by booking your domestic flight 34 to 86 days in advance compared to last-minute reservations made 6 to 12 days out. You could also reduce costs by buying your fare on a Sunday, as it's 6% cheaper on average than a Monday, the most expensive day to book.* Get your timing spot on, and you can enjoy significant savings on domestic flights.*Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

Filter your results by "Early Morning" and "Morning" to see the earliest departures from SEA to DSM. Jetting off early means flight cancellations are less likely.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.

Delta Air Lines makes traveling from SEA to DSM enjoyable with an excellent in-flight experience and a rewarding loyalty program. You may even earn points with Delta SkyMiles. Don't forget to join our free One Key™ rewards program to earn OneKeyCash™*, which can be redeemed on future travel.*OneKeyCash™ disclaimer - OneKeyCash™ is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.