$571 Cheap Flights from Cairo (CAI) to Panama City (PTY)

View $571 flight on Sat, Jan 31, 2026Opens in a new window

Popular airlines from Cairo Intl. Airport (CAI) to Tocumen Intl. Airport (PTY)

Cheap Flights from Cairo to Panama City (CAI-PTY)

Prices were available within the past 7 days and start at $571 for one-way flights and $1,019 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Sat, Dec 13 - Thu, Jan 8
CAI
Cairo
PTY
Panama City
$1,019 Roundtrip, found 4 days ago
$1,019
Roundtrip
found 4 days ago
Select American Airlines flight, departing Sat, Dec 13 from Cairo to Panama City, returning Thu, Jan 8, priced at $1,019 found 4 days ago
Iberia
Fri, Sep 12 - Thu, Oct 2
CAI
Cairo
PTY
Panama City
$1,107 Roundtrip, found 6 days ago
$1,107
Roundtrip
found 6 days ago
Select Iberia flight, departing Fri, Sep 12 from Cairo to Panama City, returning Thu, Oct 2, priced at $1,107 found 6 days ago
Lufthansa
Wed, Oct 1 - Wed, Oct 15
CAI
Cairo
PTY
Panama City
$1,155 Roundtrip, found 3 days ago
$1,155
Roundtrip
found 3 days ago
Select Lufthansa flight, departing Wed, Oct 1 from Cairo to Panama City, returning Wed, Oct 15, priced at $1,155 found 3 days ago
Lufthansa
Wed, Oct 1 - Wed, Oct 15
CAI
Cairo
PTY
Panama City
$1,187 Roundtrip, found 3 days ago
$1,187
Roundtrip
found 3 days ago
Select Lufthansa flight, departing Wed, Oct 1 from Cairo to Panama City, returning Wed, Oct 15, priced at $1,187 found 3 days ago
Lufthansa
Wed, Oct 1 - Wed, Oct 15
CAI
Cairo
PTY
Panama City
$1,201 Roundtrip, found 3 days ago
$1,201
Roundtrip
found 3 days ago
Select Lufthansa flight, departing Wed, Oct 1 from Cairo to Panama City, returning Wed, Oct 15, priced at $1,201 found 3 days ago
Lufthansa
Wed, Oct 1 - Wed, Oct 15
CAI
Cairo
PTY
Panama City
$1,233 Roundtrip, found 3 days ago
$1,233
Roundtrip
found 3 days ago
Select Lufthansa flight, departing Wed, Oct 1 from Cairo to Panama City, returning Wed, Oct 15, priced at $1,233 found 3 days ago
Iberia
Fri, Sep 26 - Wed, Dec 24
CAI
Cairo
PTY
Panama City
$1,241 Roundtrip, found 1 day ago
$1,241
Roundtrip
found 1 day ago
Select Iberia flight, departing Fri, Sep 26 from Cairo to Panama City, returning Wed, Dec 24, priced at $1,241 found 1 day ago
Iberia
Fri, Oct 3 - Thu, Oct 23
CAI
Cairo
PTY
Panama City
$1,245 Roundtrip, found 3 days ago
$1,245
Roundtrip
found 3 days ago
Select Iberia flight, departing Fri, Oct 3 from Cairo to Panama City, returning Thu, Oct 23, priced at $1,245 found 3 days ago
Qatar Airways
Fri, Oct 3 - Thu, Oct 23
CAI
Cairo
PTY
Panama City
$1,331 Roundtrip, found 3 days ago
$1,331
Roundtrip
found 3 days ago
Select Qatar Airways flight, departing Fri, Oct 3 from Cairo to Panama City, returning Thu, Oct 23, priced at $1,331 found 3 days ago
Air France
Tue, Oct 7 - Wed, Jan 7
CAI
Cairo
PTY
Panama City
$1,352 Roundtrip, found 13 hours ago
$1,352
Roundtrip
found 13 hours ago
Select Air France flight, departing Tue, Oct 7 from Cairo to Panama City, returning Wed, Jan 7, priced at $1,352 found 13 hours ago

Alternative airports near Panama City

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Tocumen Intl. PTY. Cheapest option available. Average driving time to city center is 16 minutes. Flights from $1,107
PTY
Tocumen Intl.
Cheapest
Average driving time to city center16 min
Flights from $1,107
Flights from Cairo (CAI) to Panama City (PTY)
Origin airport
Cairo Intl.
Destination airport
Tocumen Intl.
Airlines serving
Emirates, Iberia, Qatar Airways
Roundtrip price
$1,019
Distance
7112 mi

Cairo to Panama City Flights

The cheapest times to fly from Cairo to Panama City

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Cairo to Panama City are during the month of December. You can find some of the cheapest flights from Cairo to Panama City with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Cairo to Panama City

Sunday is one of the best days to book for cheap flights from Cairo to Panama City: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Cairo to Panama City

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Cairo to Panama City in 2025. You can also book with separate airlines for your outbound and return journeys, from $571 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Cairo to Panama City flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Cairo to Panama City airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Cairo Intl. Airport (CAI) to Tocumen Intl. Airport (PTY) cost?
Secure a cheap one-way flight from $571 or cheap return flight from $1,019 from Cairo Intl. Airport (CAI) to Tocumen Intl. Airport (PTY) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Cairo Intl. Airport (CAI) to Tocumen Intl. Airport (PTY)?
December is the least expensive month to fly from CAI to PTY. Avoiding peak travel times is often the key to better flight prices.
What is the cheapest airline that flies from Cairo Intl. Airport (CAI) to Tocumen Intl. Airport (PTY)?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that'll take you from CAI to PTY. Then, sort your results by "Price (lowest to highest)" to score a good deal.
How many flights per day from Cairo Intl. Airport (CAI) to Tocumen Intl. Airport (PTY)?
Direct flights from Cairo Intl. Airport (CAI) to Tocumen Intl. Airport (PTY) aren't available daily, so you'll need to take a flight with a layover. Explore your options with Expedia's filters. Enter your travel dates and pick either "1 Stop" or "2+ Stops."
What day of the week has the most flights from CAI to PTY?
You'll typically find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can change from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Cairo Intl. Airport (CAI) to Tocumen Intl. Airport (PTY)?
To touch down at Tocumen Intl. Airport (PTY) on schedule, choose a flight that takes off from Cairo Intl. Airport (CAI) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Cairo Intl. Airport (CAI) to Tocumen Intl. Airport (PTY) last-minute?
Waiting until just before your departure to book your flight from CAI to PTY often results in higher prices. While you may find some last-minute deals, they aren't always guaranteed. Allow some flexibility in your schedule to maximize your chances of scoring a bargain.
Is it cheaper to book a CAI to PTY flight and hotel package?
You'll typically save money by booking a CAI to PTY flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's easy to manage it all in one place. After selecting your ideal accommodations and flights, you can add extras like tours, activities and car rentals.
Can I cancel or change the date of my flight from Cairo Intl. Airport (CAI) to Tocumen Intl. Airport (PTY)?
It's usually possible to cancel or reschedule your CAI to PTY flight. However, if the booking was made more than 24 hours ago, additional charges may apply. Refer to your airline's policies in your itinerary to see what changes are allowed and whether any costs are involved. You'll also find further details on our Customer Service portal.

Explore a world of travel with Expedia

*Available to One Key members.