$109 Cheap Flights from Columbus (CMH) to St. Louis (STL)

View $109 flight on Tue, Dec 30, 2025Opens in a new window

Popular airlines from John Glenn Columbus Intl. Airport (CMH) to St. Louis Lambert Intl. Airport (STL)

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Cheap Flights from Columbus to St. Louis (CMH-STL)

Prices were available within the past 7 days and start at $109 for one-way flights and $162 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frontier Airlines
Fri, Sep 12 - Thu, Sep 18
CMH
Columbus
STL
St. Louis
$162 Roundtrip, found 4 hours ago
$162
Roundtrip
found 4 hours ago
Select Frontier Airlines flight, departing Fri, Sep 12 from Columbus to St. Louis, returning Thu, Sep 18, priced at $162 found 4 hours ago
Frontier Airlines
Fri, Sep 12 - Sat, Sep 13
CMH
Columbus
STL
St. Louis
$180 Roundtrip, found 4 hours ago
$180
Roundtrip
found 4 hours ago
Select Frontier Airlines flight, departing Fri, Sep 12 from Columbus to St. Louis, returning Sat, Sep 13, priced at $180 found 4 hours ago
Frontier Airlines
Fri, Oct 3 - Fri, Oct 10
CMH
Columbus
STL
St. Louis
$195 Roundtrip, found 13 hours ago
$195
Roundtrip
found 13 hours ago
Select Frontier Airlines flight, departing Fri, Oct 3 from Columbus to St. Louis, returning Fri, Oct 10, priced at $195 found 13 hours ago
Frontier Airlines
Thu, Sep 11 - Thu, Sep 18
CMH
Columbus
STL
St. Louis
$197 Roundtrip, found 4 hours ago
$197
Roundtrip
found 4 hours ago
Select Frontier Airlines flight, departing Thu, Sep 11 from Columbus to St. Louis, returning Thu, Sep 18, priced at $197 found 4 hours ago
Frontier Airlines
Sat, Sep 13 - Sat, Sep 20
CMH
Columbus
STL
St. Louis
$198 Roundtrip, found 4 hours ago
$198
Roundtrip
found 4 hours ago
Select Frontier Airlines flight, departing Sat, Sep 13 from Columbus to St. Louis, returning Sat, Sep 20, priced at $198 found 4 hours ago
Frontier Airlines
Thu, Sep 11 - Sat, Sep 13
CMH
Columbus
STL
St. Louis
$215 Roundtrip, found 4 hours ago
$215
Roundtrip
found 4 hours ago
Select Frontier Airlines flight, departing Thu, Sep 11 from Columbus to St. Louis, returning Sat, Sep 13, priced at $215 found 4 hours ago
Southwest Airlines
Tue, Sep 9 - Wed, Sep 10
CMH
Columbus
STL
St. Louis
$217 Roundtrip, found 3 days ago
$217
Roundtrip
found 3 days ago
Select Southwest Airlines flight, departing Tue, Sep 9 from Columbus to St. Louis, returning Wed, Sep 10, priced at $217 found 3 days ago
Delta
Tue, Sep 9 - Wed, Sep 10
CMH
Columbus
STL
St. Louis
$222 Roundtrip, found 3 days ago
$222
Roundtrip
found 3 days ago
Select Delta flight, departing Tue, Sep 9 from Columbus to St. Louis, returning Wed, Sep 10, priced at $222 found 3 days ago
American Airlines
Tue, Sep 9 - Wed, Sep 10
CMH
Columbus
STL
St. Louis
$225 Roundtrip, found 3 days ago
$225
Roundtrip
found 3 days ago
Select American Airlines flight, departing Tue, Sep 9 from Columbus to St. Louis, returning Wed, Sep 10, priced at $225 found 3 days ago
United
Tue, Oct 14 - Sat, Oct 18
CMH
Columbus
STL
St. Louis
$232 Roundtrip, found 2 days ago
$232
Roundtrip
found 2 days ago
Select United flight, departing Tue, Oct 14 from Columbus to St. Louis, returning Sat, Oct 18, priced at $232 found 2 days ago

Find the cheapest month to fly from Columbus (CMH) to St. Louis (STL)

August is typically the cheapest month to fly

From $144 - $602 per traveler.

Graph displaying average flight prices per month

Alternative airports near St. Louis

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Lambert-St. Louis Intl. STL. Cheapest option available. Average driving time to city center is 20 minutes. Flights from $278
STL
Lambert-St. Louis Intl.
Cheapest
Average driving time to city center20 min
Flights from $278
0
Flights from Columbus (CMH) to St. Louis (STL)
Origin airport
John Glenn Columbus Intl.
Destination airport
Lambert-St. Louis Intl.
Airlines serving
American Airlines, Delta, Frontier Airlines, Southwest Airlines, United
Roundtrip price
$162
Distance
408 mi

Columbus to St. Louis Flights

The cheapest times to fly from Columbus to St. Louis

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Columbus to St. Louis are during the month of September. You can find some of the cheapest flights from Columbus to St. Louis with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Columbus to St. Louis

Sunday is one of the best days to book for cheap flights from Columbus to St. Louis: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Columbus to St. Louis

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Columbus to St. Louis in 2025. You can also book with separate airlines for your outbound and return journeys, from $109 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Columbus to St. Louis flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Columbus to St. Louis airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from John Glenn Columbus Intl. Airport (CMH) to Lambert-St. Louis Intl. Airport (STL) cost?
Grab a cheap one-way flight from $109 or cheap return flight from $162 from John Glenn Columbus Intl. Airport (CMH) to Lambert-St. Louis Intl. Airport (STL) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from John Glenn Columbus Intl. Airport (CMH) to Lambert-St. Louis Intl. Airport (STL)?
September is the cheapest month to fly from CMH to STL. Avoiding peak travel times is often the key to landing a great deal.
Which airlines fly direct from John Glenn Columbus Intl. Airport (CMH) to Lambert-St. Louis Intl. Airport (STL)?
Take a direct flight with Southwest Airlines and go straight from John Glenn Columbus Intl. Airport (CMH) to Lambert-St. Louis Intl. Airport (STL).
What is the cheapest airline that flies from John Glenn Columbus Intl. Airport (CMH) to Lambert-St. Louis Intl. Airport (STL)?
Expedia's filter tool lets you easily compare airlines, flight times and baggage options all in one place. Tailor the search to your trip, then sort by "Price (lowest to highest)" to find out which carrier offers the cheapest CMH to STL flight.
How many flights per day from John Glenn Columbus Intl. Airport (CMH) to Lambert-St. Louis Intl. Airport (STL)?
On average, only 1 nonstop flight departs daily from John Glenn Columbus Intl. Airport (CMH) to Lambert-St. Louis Intl. Airport (STL). Want more options? Use our filters to discover flights with layovers and add a new destination to your journey.
What are the most popular departure times for flights from John Glenn Columbus Intl. Airport (CMH) to Lambert-St. Louis Intl. Airport (STL)?
The 8 AM departures from CMH to STL are the top choice for many travelers. Greater demand means you'll likely pay more for these departures. If you're hoping to save money, book during off-peak hours.
What day of the week has the most flights from CMH to STL?
If you fly on a Friday, you'll get the biggest range of options for flights from John Glenn Columbus Intl. Airport (CMH) to Lambert-St. Louis Intl. Airport (STL).
What is the earliest flight from John Glenn Columbus Intl. Airport (CMH) to Lambert-St. Louis Intl. Airport (STL)?
John Glenn Columbus Intl. Airport (CMH)'s first flight to Lambert-St. Louis Intl. Airport (STL) is at approximately 7:40AM UTC-5. With a total travel time of 1h 40m, you'll touch down at around 8:20AM UTC-6.
How long does it take to fly from John Glenn Columbus Intl. Airport (CMH) to Lambert-St. Louis Intl. Airport (STL)?
It usually takes 1 hour and 32 minutes to travel the 410 mi from CMH to STL.
What is the best time to fly from John Glenn Columbus Intl. Airport (CMH) to Lambert-St. Louis Intl. Airport (STL)?
To reach Lambert-St. Louis Intl. Airport (STL) on schedule, choose a flight that takes off from John Glenn Columbus Intl. Airport (CMH) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for St. Louis from John Glenn Columbus Intl. Airport (CMH)?
If you're traveling on a direct flight from John Glenn Columbus Intl. Airport (CMH) to St. Louis, Lambert-St. Louis Intl. Airport (STL) is the only airport you can land at.
Is it cheaper to buy a plane ticket from John Glenn Columbus Intl. Airport (CMH) to Lambert-St. Louis Intl. Airport (STL) last-minute?
Waiting until just before your trip to book your flight from CMH to STL often results in higher prices. While you might find some last-minute discounts, they're not always guaranteed. Keep your travel schedule open to maximize your chances of landing a bargain.
Is it cheaper to book a CMH to STL flight and hotel package?
Booking a CMH to STL flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your trip in one place. Choose from our impressive range of accommodations and then add activities, car rentals and flights to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from John Glenn Columbus Intl. Airport (CMH) to Lambert-St. Louis Intl. Airport (STL)?
If you reserved your CMH to STL flight within the last 24 hours, you may be able to modify or cancel it at no cost. Depending on the airline and the type of ticket you purchased, additional charges may apply for changes beyond that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal for more information.

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*Available to One Key members.