$235 Cheap Flights from Columbia (COU) to Myrtle Beach (MYR)

View $235 flight on Wed, Sep 9, 2026Opens in a new window

Popular airlines from Columbia, MO (COU-Columbia Regional) to Myrtle Beach Intl. Airport (MYR)

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Cheap Flights from Columbia to Myrtle Beach (COU-MYR)

Prices were available within the past 7 days and start at $235 for one-way flights and $410 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Wed, Sep 9 - Tue, Sep 15
COU
Columbia
MYR
Myrtle Beach
$410 Roundtrip, found 5 days ago
$410
Roundtrip
found 5 days ago
Select American Airlines flight, departing Wed, Sep 9 from Columbia to Myrtle Beach, returning Tue, Sep 15, priced at $410 found 5 days ago
American Airlines
Wed, Jan 21 - Wed, Jan 28
COU
Columbia
MYR
Myrtle Beach
$416 Roundtrip, just found
$416
Roundtrip
just found
Select American Airlines flight, departing Wed, Jan 21 from Columbia to Myrtle Beach, returning Wed, Jan 28, priced at $416 just found
American Airlines
Wed, Jan 21 - Wed, Jan 28
COU
Columbia
MYR
Myrtle Beach
$421 Roundtrip, just found
$421
Roundtrip
just found
Select American Airlines flight, departing Wed, Jan 21 from Columbia to Myrtle Beach, returning Wed, Jan 28, priced at $421 just found
United
Tue, May 5 - Tue, May 19
COU
Columbia
MYR
Myrtle Beach
$421 Roundtrip, found 6 days ago
$421
Roundtrip
found 6 days ago
Select United flight, departing Tue, May 5 from Columbia to Myrtle Beach, returning Tue, May 19, priced at $421 found 6 days ago
American Airlines
Wed, Jan 21 - Thu, Jan 29
COU
Columbia
MYR
Myrtle Beach
$443 Roundtrip, just found
$443
Roundtrip
just found
Select American Airlines flight, departing Wed, Jan 21 from Columbia to Myrtle Beach, returning Thu, Jan 29, priced at $443 just found
American Airlines
Wed, Jan 21 - Wed, Jan 28
COU
Columbia
MYR
Myrtle Beach
$446 Roundtrip, just found
$446
Roundtrip
just found
Select American Airlines flight, departing Wed, Jan 21 from Columbia to Myrtle Beach, returning Wed, Jan 28, priced at $446 just found
American Airlines
Thu, Dec 18 - Sun, Dec 21
COU
Columbia
MYR
Myrtle Beach
$447 Roundtrip, found 16 hours ago
$447
Roundtrip
found 16 hours ago
Select American Airlines flight, departing Thu, Dec 18 from Columbia to Myrtle Beach, returning Sun, Dec 21, priced at $447 found 16 hours ago
United
Wed, Dec 31 - Wed, Jan 14
COU
Columbia
MYR
Myrtle Beach
$448 Roundtrip, found 3 days ago
$448
Roundtrip
found 3 days ago
Select United flight, departing Wed, Dec 31 from Columbia to Myrtle Beach, returning Wed, Jan 14, priced at $448 found 3 days ago
American Airlines
Wed, Jan 21 - Wed, Jan 28
COU
Columbia
MYR
Myrtle Beach
$451 Roundtrip, just found
$451
Roundtrip
just found
Select American Airlines flight, departing Wed, Jan 21 from Columbia to Myrtle Beach, returning Wed, Jan 28, priced at $451 just found
American Airlines
Thu, Dec 18 - Sun, Dec 21
COU
Columbia
MYR
Myrtle Beach
$456 Roundtrip, found 16 hours ago
$456
Roundtrip
found 16 hours ago
Select American Airlines flight, departing Thu, Dec 18 from Columbia to Myrtle Beach, returning Sun, Dec 21, priced at $456 found 16 hours ago

Alternative airports near Myrtle Beach

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Myrtle Beach Intl. Airport MYR. Cheapest and Closest option available. Average driving time to city center is 6 minutes. Flights from $573
MYR
Myrtle Beach Intl. Airport
CheapestClosest
Average driving time to city center6 min
Flights from $573

Frequently asked questions

How much does a flight from Columbia Regional Airport (COU) to Myrtle Beach Intl. Airport (MYR) cost?
Lock in a cheap one-way flight from $235 or cheap return flight from $410 from Columbia Regional Airport (COU) to Myrtle Beach Intl. Airport (MYR) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Columbia Regional Airport (COU) to Myrtle Beach Intl. Airport (MYR)?
Planning your trip for September may help you find better deals, as it's the cheapest month for flights between COU and MYR. You'll typically find the lowest fares during the off-season.
What is the cheapest airline that flies from Columbia Regional Airport (COU) to Myrtle Beach Intl. Airport (MYR)?
Use the filters on Expedia to compare different airlines and find the most affordable carrier that'll take you from COU to MYR. Then, sort your results by "Price (lowest to highest)" to pick up a good deal.
How many flights per day from Columbia Regional Airport (COU) to Myrtle Beach Intl. Airport (MYR)?
You'll have to catch a flight with a layover if you're traveling from Columbia Regional Airport (COU) to Myrtle Beach Intl. Airport (MYR). Direct flights don't operate daily on this route. However, just filter your search to include one or two stops to discover an option that works for you.
What day of the week has the most flights from COU to MYR?
Usually you'll have the most choice when it comes to flights on a Friday. Tuesdays are often the quietest.* However, this can vary depending on the season, carrier and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Columbia Regional Airport (COU) to Myrtle Beach Intl. Airport (MYR)?
To arrive at Myrtle Beach Intl. Airport (MYR) on schedule, opt for a flight that leaves Columbia Regional Airport (COU) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Columbia Regional Airport (COU) to Myrtle Beach Intl. Airport (MYR) last-minute?
Booking your ticket from COU to MYR right before your getaway is typically more expensive. But if there's some wiggle room with your itinerary, you could snag a cheap last-minute fare.
Is it cheaper to book a COU to MYR flight and hotel package?
Booking a COU to MYR flight and hotel package is generally cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your trip all in one place. Pick from our impressive range of stays and then add flights, car rentals and activities to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Columbia Regional Airport (COU) to Myrtle Beach Intl. Airport (MYR)?
In most instances, you're able to reschedule or cancel your COU to MYR flight. However, additional charges may apply, especially if you made your booking more than 24 hours ago. Double-check your itinerary for the airline's fees and policies on flight changes, or if you want further information, head to our Customer Service portal.

Travel information

Origin airport
Columbia Regional
Destination airport
Myrtle Beach Intl.
Airlines serving
American Airlines
Roundtrip price
$410
Distance
820 mi

Book with confidence

Columbia to Myrtle Beach Flights

The cheapest times to fly from Columbia to Myrtle Beach

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Columbia to Myrtle Beach are during the month of September. You can find some of the cheapest flights from Columbia to Myrtle Beach with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Columbia to Myrtle Beach

Sunday is one of the best days to book for cheap flights from Columbia to Myrtle Beach: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Columbia to Myrtle Beach

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Columbia to Myrtle Beach in 2025. You can also book with separate airlines for your outbound and return journeys, from $235 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Columbia to Myrtle Beach flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Columbia to Myrtle Beach airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Columbia to Myrtle Beach Flights

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*Available to One Key members.