A cityscape with a river, bridges, and a large mosque.

$618 Cheap Flights from Des Moines (DSM) to Cairo (CAI)

View $618 flight on Mon, Sep 28, 2026Opens in a new window

Popular airlines from Des Moines International Airport (DSM) to Cairo Intl. Airport (CAI)

  • Be in the know

    Get alerts if flight prices drop or rise*

  • Book smarter

    Save up to 30% on select hotels after you book a flight*

  • Earn twice

    Earn your airline miles on top of our OneKeyCash
    Learn about One Key

Cheap Flights from Des Moines to Cairo (DSM-CAI)

Prices were available within the past 7 days and start at $618 for one-way flights and $991 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Wed, Nov 11 - Sat, Nov 21
DSM
Des Moines
CAI
Cairo
$991 Roundtrip, found 2 days ago
$991
Roundtrip
found 2 days ago
Select Delta flight, departing Wed, Nov 11 from Des Moines to Cairo, returning Sat, Nov 21, priced at $991 found 2 days ago
Delta
Wed, Nov 11 - Fri, Nov 20
DSM
Des Moines
CAI
Cairo
$1,000 Roundtrip, found 6 hours ago
$1,000
Roundtrip
found 6 hours ago
Select Delta flight, departing Wed, Nov 11 from Des Moines to Cairo, returning Fri, Nov 20, priced at $1,000 found 6 hours ago
Delta
Wed, Feb 3 - Wed, Feb 10
DSM
Des Moines
CAI
Cairo
$1,001 Roundtrip, found 1 hour ago
$1,001
Roundtrip
found 1 hour ago
Select Delta flight, departing Wed, Feb 3 from Des Moines to Cairo, returning Wed, Feb 10, priced at $1,001 found 1 hour ago
British Airways
Wed, Feb 3 - Wed, Feb 10
DSM
Des Moines
CAI
Cairo
$1,007 Roundtrip, found 1 hour ago
$1,007
Roundtrip
found 1 hour ago
Select British Airways flight, departing Wed, Feb 3 from Des Moines to Cairo, returning Wed, Feb 10, priced at $1,007 found 1 hour ago
KLM
Wed, Dec 2 - Wed, Dec 9
DSM
Des Moines
CAI
Cairo
$1,008 Roundtrip, found 18 hours ago
$1,008
Roundtrip
found 18 hours ago
Select KLM flight, departing Wed, Dec 2 from Des Moines to Cairo, returning Wed, Dec 9, priced at $1,008 found 18 hours ago
British Airways
Wed, Nov 11 - Fri, Nov 20
DSM
Des Moines
CAI
Cairo
$1,016 Roundtrip, found 6 hours ago
$1,016
Roundtrip
found 6 hours ago
Select British Airways flight, departing Wed, Nov 11 from Des Moines to Cairo, returning Fri, Nov 20, priced at $1,016 found 6 hours ago
American Airlines
Wed, Feb 3 - Wed, Feb 10
DSM
Des Moines
CAI
Cairo
$1,017 Roundtrip, found 1 hour ago
$1,017
Roundtrip
found 1 hour ago
Select American Airlines flight, departing Wed, Feb 3 from Des Moines to Cairo, returning Wed, Feb 10, priced at $1,017 found 1 hour ago
British Airways
Mon, Jan 18 - Mon, Jan 25
DSM
Des Moines
CAI
Cairo
$1,025 Roundtrip, found 20 hours ago
$1,025
Roundtrip
found 20 hours ago
Select British Airways flight, departing Mon, Jan 18 from Des Moines to Cairo, returning Mon, Jan 25, priced at $1,025 found 20 hours ago
American Airlines
Wed, Nov 4 - Tue, Nov 10
DSM
Des Moines
CAI
Cairo
$1,026 Roundtrip, found 4 days ago
$1,026
Roundtrip
found 4 days ago
Select American Airlines flight, departing Wed, Nov 4 from Des Moines to Cairo, returning Tue, Nov 10, priced at $1,026 found 4 days ago
Air France
Sat, Nov 14 - Sat, Nov 21
DSM
Des Moines
CAI
Cairo
$1,034 Roundtrip, found 1 day ago
$1,034
Roundtrip
found 1 day ago
Select Air France flight, departing Sat, Nov 14 from Des Moines to Cairo, returning Sat, Nov 21, priced at $1,034 found 1 day ago

What you need to know for your flight from Des Moines Intl. to Cairo Intl.

Des Moines (DSM) to Cairo (CAI) at a glance

Travel internationally with a selection of airlines offering flights from Des Moines (DSM) to Cairo (CAI) on this long-haul route. Evaluate options from full-service carriers to discover the itinerary that aligns with your budget, travel schedule, and plans as you delve into Cairo’s iconic attractions and vibrant neighborhoods. Here, you’ll find essential information regarding flights from Des Moines International Airport (DSM) to Cairo International Airport (CAI).

  • Fastest flight duration: around 14h 30m in-flight, plus roughly 6 hours total layover with two or more stops
  • Route distance: roughly 6,400 miles (10,300 km)
  • Flights per week: around 7 departures on average
  • Typical fares (one-way): economy tickets often range from $555–$880, depending on seasonality and how far ahead you book

Flights from Des Moines International Airport (DSM) to Cairo International Airport (CAI)

Based on the latest traveler bookings, here are the top airlines favored for flights from Des Moines to Cairo, often selected for their multi-stop options. Common layovers include O'Hare International Airport (ORD) with a layover of about 2 hours and 30 minutes, Frankfurt International Airport (FRA) also around 2 hours and 30 minutes, and Heathrow Airport (LHR) with a layover of approximately 2 hours and 45 minutes. These choices allow you to customize your itinerary based on price, total travel time, and cabin class.

  • United: This comprehensive airline provides multi-stop services, handling about 40% of the flights on this route. One-way fare prices generally fall between $590 and $810. Passengers can expect an in-flight duration of 14 hours and 30 minutes, with the overall travel time, including layovers, around 21 hours.

How to find the best prices for flights from Des Moines (DSM) to Cairo (CAI)

Getting some of the best deals on flights from Des Moines to Cairo is all about timing and flexibility. Here are some key tips to help you save:

  1. Best times to book and fly: cheaper fares are generally available when booking within 2 weeks, although most travelers tend to book at least 2 months in advance. Departures in the afternoon (12pm-6pm) usually offer lower prices, while evening flights (6pm-12am) are the most popular. Additionally, flying on Monday provides both cheaper prices and is the most favored travel day.
  2. Set up price alerts: stay updated on price changes by using Expedia's Price Tracker. Receive alerts when fares drop for your selected route.
  3. Bundle and save: bundle your flight and hotel to save on Expedia, or unlock a hotel deal after booking your flight.*
  4. Compare flight options: use Expedia's search tool to compare airlines, routes, direct vs. non-direct flights, and flight times. You can also sort by price to find the most affordable options.
  5. Stay flexible with dates: being open to different travel days can sometimes help you find better prices on flights and hotels.
  6. Think about luggage: nowadays, it's important to check the airline's baggage policies to find the best value. That may be paying for an additional carry-on bag or booking a ticket with checked luggage included. Either way, double-check your allowance before confirming your booking to avoid excess baggage fees at the airport.

*Members only. Savings vary and are not available on all bundles. Select hotels.

Arriving at Cairo International Airport from Des Moines International Airport

Cairo welcomes travelers from Des Moines with a range of transport options based on price, convenience, and proximity. Here's how to reach Cairo efficiently:

  • Hotel transfer: Transfers offer a convenient way to reach your hotel in Cairo, with private rides that can be arranged in advance.
  • Car rental: Renting a car from Cairo International Airport is a great option if you plan to explore and sightsee beyond the city. Browse cheap car rentals at Cairo International Airport on Expedia.
  • Taxi/ride-hailing: Taxis and ride-hailing services may be available from designated pickup areas outside the terminal, check locally on arrival.
  • Public transportation: From Cairo International Airport, travelers can conveniently access El Nozha Station, a metro station located about 3.8 miles away by car, and Adly Mansour Station, a train station situated approximately 4 miles from the airport, both easily reached by car.

Frequently asked questions

How much does a flight from Des Moines, IA (DSM-Des Moines Intl.) to Cairo (CAI-Cairo Intl.) cost?
You can find cheap one-way flights from $618 and cheap return flights from $991 Des Moines, IA (DSM-Des Moines Intl.) to Cairo (CAI-Cairo Intl.) with Expedia. Return flights typically cost between $1334 and $4794. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Des Moines, IA (DSM-Des Moines Intl.) to Cairo (CAI-Cairo Intl.) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from Des Moines, IA (DSM-Des Moines Intl.) to Cairo (CAI-Cairo Intl.)?
The cheapest month to fly from DSM to CAI is November when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you're able to. Use the calendar view in your search to see which months have low fares on this route.
Which airlines fly direct from Des Moines, IA (DSM-Des Moines Intl.) to Cairo (CAI-Cairo Intl.)?
Enter DSM to CAI and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Des Moines, IA (DSM-Des Moines Intl.) to Cairo (CAI-Cairo Intl.)?
KLM is one of the cheapest airlines offering connecting flights from Des Moines, IA (DSM) to Cairo (CAI) with a layover in Hartsfield-Jackson Atlanta Intl. (ATL), starting from around $1,221. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.*Prices based on flights available on Expedia in the last year.
How do I find cheap flights from Des Moines, IA (DSM-Des Moines Intl.) to Cairo (CAI-Cairo Intl.)?
To find a cheap flight from Des Moines, IA (DSM-Des Moines Intl.) to Cairo (CAI-Cairo Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Des Moines, IA (DSM-Des Moines Intl.) to Cairo (CAI-Cairo Intl.)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
What is the earliest flight from Des Moines, IA (DSM-Des Moines Intl.) to Cairo (CAI-Cairo Intl.)?
The earliest flight from Des Moines, IA (DSM-Des Moines Intl.) to Cairo (CAI-Cairo Intl.) generally departs at around 5:00 AM, operated by American Airlines and British Airways. This seasonal service is available in July, allowing you to start your journey to Egypt bright and early. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What are the most popular departure times for flights from Des Moines, IA (DSM-Des Moines Intl.) to Cairo (CAI-Cairo Intl.)?
The most popular departure times for flights from Des Moines Intl. (DSM) to Cairo Intl. (CAI) are in the early afternoon, from 12pm to 3pm. About 43% of passengers prefer this time window. Major carriers like American Airlines and Qatar Airways operate flights during this period. This timing is great for travelers who want to make the most of their morning before heading to Cairo.
How long does it take to fly from Des Moines, IA (DSM-Des Moines Intl.) to Cairo (CAI-Cairo Intl.)?
Flights from DSM to CAI with one stop typically take around 21 hours 30 minutes, covering approximately 6,374 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Des Moines, IA (DSM-Des Moines Intl.) to Cairo (CAI-Cairo Intl.)?
Business class seats are offered on the DSM to CAI route. Airlines that offer business class service on this route include:

  • American Airlines
  • United Airlines
  • Delta Air Lines

First class is available with United Airlines.
How do I earn miles on a Des Moines, IA (DSM-Des Moines Intl.) to Cairo (CAI-Cairo Intl.) flight with Expedia?
It's easy to earn miles on a Des Moines, IA (DSM-Des Moines Intl.) to Cairo (CAI-Cairo Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Cairo from Des Moines Intl. (DSM)?
From Des Moines Intl. (DSM), you can fly typically into Cairo Intl. (CAI) to reach Cairo. Some flights may connect through major hubs like O'Hare Intl. (ORD), George Bush Intercontinental (IAH), Denver Intl. (DEN) before reaching Cairo. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Des Moines, IA (DSM-Des Moines Intl.) to Cairo (CAI-Cairo Intl.) at the last minute?
Typically, booking a last minute flight from Des Moines, IA (DSM-Des Moines Intl.) to Cairo (CAI-Cairo Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Des Moines, IA (DSM-Des Moines Intl.) to Cairo (CAI-Cairo Intl.) flight and hotel package?
Securing a Des Moines, IA (DSM-Des Moines Intl.) to Cairo (CAI-Cairo Intl.) Cairo Vacation Packages is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Des Moines, IA (DSM-Des Moines Intl.) to Cairo (CAI-Cairo Intl.)?
If you booked your Des Moines, IA (DSM-Des Moines Intl.) to Cairo (CAI-Cairo Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Des Moines Intl.
Destination airport
Cairo Intl.
Airlines serving
Air France, American Airlines, British Airways, Delta, KLM, Lufthansa, Qatar Airways, United
Roundtrip price
$991
Distance
6373 mi

Book with confidence

Des Moines to Cairo Flights

The cheapest times to fly from Des Moines to Cairo

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Des Moines to Cairo are during the month of November. You can find some of the cheapest flights from Des Moines to Cairo with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Des Moines to Cairo

Sunday is one of the best days to book for cheap flights from Des Moines to Cairo: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Des Moines to Cairo

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Des Moines to Cairo in 2026. You can also book with separate airlines for your outbound and return journeys, from $618 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Des Moines to Cairo flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Des Moines to Cairo airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Des Moines to Cairo Flights

*Flight schedules are subject to change.

*Available to One Key members.

 

Explore a world of travel with Expedia