$107 Cheap Flights from Des Moines (DSM) to Memphis (MEM)

View $107 flight on Fri, Feb 20, 2026Opens in a new window

Popular airlines from Des Moines International Airport (DSM) to Memphis International Airport (MEM)

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Cheap Flights from Des Moines to Memphis (DSM-MEM)

Prices were available within the past 7 days and start at $107 for one-way flights and $213 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Sat, Jan 17 - Tue, Jan 20
DSM
Des Moines
MEM
Memphis
$213 Roundtrip, found 16 hours ago
$213
Roundtrip
found 16 hours ago
Select American Airlines flight, departing Sat, Jan 17 from Des Moines to Memphis, returning Tue, Jan 20, priced at $213 found 16 hours ago
Delta
Sat, Jan 17 - Tue, Jan 20
DSM
Des Moines
MEM
Memphis
$213 Roundtrip, found 16 hours ago
$213
Roundtrip
found 16 hours ago
Select Delta flight, departing Sat, Jan 17 from Des Moines to Memphis, returning Tue, Jan 20, priced at $213 found 16 hours ago
United
Sat, Jan 17 - Tue, Jan 20
DSM
Des Moines
MEM
Memphis
$213 Roundtrip, found 16 hours ago
$213
Roundtrip
found 16 hours ago
Select United flight, departing Sat, Jan 17 from Des Moines to Memphis, returning Tue, Jan 20, priced at $213 found 16 hours ago
Delta
Sat, Jan 17 - Tue, Jan 20
DSM
Des Moines
MEM
Memphis
$214 Roundtrip, found 16 hours ago
$214
Roundtrip
found 16 hours ago
Select Delta flight, departing Sat, Jan 17 from Des Moines to Memphis, returning Tue, Jan 20, priced at $214 found 16 hours ago
United
Sat, Jan 17 - Tue, Jan 20
DSM
Des Moines
MEM
Memphis
$220 Roundtrip, found 16 hours ago
$220
Roundtrip
found 16 hours ago
Select United flight, departing Sat, Jan 17 from Des Moines to Memphis, returning Tue, Jan 20, priced at $220 found 16 hours ago
Southwest Airlines
Sat, Jan 17 - Tue, Jan 20
DSM
Des Moines
MEM
Memphis
$232 Roundtrip, found 16 hours ago
$232
Roundtrip
found 16 hours ago
Select Southwest Airlines flight, departing Sat, Jan 17 from Des Moines to Memphis, returning Tue, Jan 20, priced at $232 found 16 hours ago
Delta
Wed, Jan 14 - Sat, Jan 17
DSM
Des Moines
MEM
Memphis
$234 Roundtrip, found 1 day ago
$234
Roundtrip
found 1 day ago
Select Delta flight, departing Wed, Jan 14 from Des Moines to Memphis, returning Sat, Jan 17, priced at $234 found 1 day ago
Southwest Airlines
Sat, Jan 17 - Tue, Jan 20
DSM
Des Moines
MEM
Memphis
$237 Roundtrip, found 16 hours ago
$237
Roundtrip
found 16 hours ago
Select Southwest Airlines flight, departing Sat, Jan 17 from Des Moines to Memphis, returning Tue, Jan 20, priced at $237 found 16 hours ago
American Airlines
Thu, Oct 30 - Fri, Oct 31
DSM
Des Moines
MEM
Memphis
$239 Roundtrip, found 3 days ago
$239
Roundtrip
found 3 days ago
Select American Airlines flight, departing Thu, Oct 30 from Des Moines to Memphis, returning Fri, Oct 31, priced at $239 found 3 days ago
Frontier Airlines
Thu, Feb 19 - Thu, Mar 5
DSM
Des Moines
MEM
Memphis
$317 Roundtrip, found 21 hours ago
$317
Roundtrip
found 21 hours ago
Select Frontier Airlines flight, departing Thu, Feb 19 from Des Moines to Memphis, returning Thu, Mar 5, priced at $317 found 21 hours ago

Find the cheapest month to fly from Des Moines (DSM) to Memphis (MEM)

September is typically the cheapest month to fly

From $157 - $486 per traveler.

Alternative airports near Memphis

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Memphis Intl. MEM. Cheapest and Closest option available. Average driving time to city center is 15 minutes. Flights from $300
MEM
Memphis Intl.
CheapestClosest
Average driving time to city center15 min
Flights from $300

Frequently asked questions

How much does a flight from Des Moines Intl. Airport (DSM) to Memphis Intl. Airport (MEM) cost?
Lock in a cheap one-way flight from $107 or cheap return flight from $213 from Des Moines Intl. Airport (DSM) to Memphis Intl. Airport (MEM) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Des Moines Intl. Airport (DSM) to Memphis Intl. Airport (MEM)?
January is the cheapest month to fly from DSM to MEM. Planning your trip for the off-season is often the key to finding better deals on flights.
What is the cheapest airline that flies from Des Moines Intl. Airport (DSM) to Memphis Intl. Airport (MEM)?
Use the filters on Expedia to compare airlines and find the cheapest carrier that'll take you from DSM to MEM. Then, sort your results by "Price (lowest to highest)" to score a good deal.
How many flights per day from Des Moines Intl. Airport (DSM) to Memphis Intl. Airport (MEM)?
Direct flights from Des Moines Intl. Airport (DSM) to Memphis Intl. Airport (MEM) aren't available daily, so you'll need to take a flight with a layover. Explore your options with our filter tool. Enter your travel dates and pick either "1 Stop" or "2+ Stops."
What day of the week has the most flights from DSM to MEM?
Generally you'll find the greatest selection of flight options on a Friday. Tuesdays tend to be the quietest.* But this can vary based on the airline, time of year and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Des Moines Intl. Airport (DSM) to Memphis Intl. Airport (MEM)?
To touch down at Memphis Intl. Airport (MEM) without delays, choose a flight that leaves from Des Moines Intl. Airport (DSM) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Des Moines Intl. Airport (DSM) to Memphis Intl. Airport (MEM) last-minute?
Holding off until right before your break to book a flight from DSM to MEM generally means paying more. While it's possible to find some last-minute offers, they aren't always guaranteed. Keep your travel plans flexible for the best chance of landing a bargain.
Is it cheaper to book a DSM to MEM flight and hotel package?
You'll generally save money by booking a DSM to MEM flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's simple to manage everything in one place. After choosing your ideal flights and accommodations, consider other add-ons like tours, car rentals and activities.
Can I cancel or change the date of my flight from Des Moines Intl. Airport (DSM) to Memphis Intl. Airport (MEM)?
Typically, you can modify or cancel your DSM to MEM flight. However, there may be additional fees, especially if you made your booking more than 24 hours ago. Double-check your itinerary for the airline's guidelines and fees on flight changes, or if you'd like more details, go to our Customer Service portal.

Travel information

Origin airport
Des Moines Intl.
Destination airport
Memphis Intl.
Airlines serving
American Airlines, Delta, Frontier Airlines, Southwest Airlines, United
Roundtrip price
$212
Distance
490 mi

Book with confidence

Des Moines to Memphis Flights

The cheapest times to fly from Des Moines to Memphis

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Des Moines to Memphis are during the month of January. You can find some of the cheapest flights from Des Moines to Memphis with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Des Moines to Memphis

Sunday is one of the best days to book for cheap flights from Des Moines to Memphis: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Des Moines to Memphis

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Des Moines to Memphis in 2025. You can also book with separate airlines for your outbound and return journeys, from $107 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Des Moines to Memphis flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Des Moines to Memphis airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Des Moines to Memphis Flights

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*Available to One Key members.