$206 Cheap Flights from Des Moines (DSM) to Medford (MFR)

View $206 flight on Sat, Dec 13, 2025Opens in a new window

Popular airlines from Des Moines International Airport (DSM) to Rogue Valley Intl. Airport (MFR)

Cheap Flights from Des Moines to Medford (DSM-MFR)

Prices were available within the past 7 days and start at $206 for one-way flights and $269 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Fri, Jan 16 - Mon, Jan 19
DSM
Des Moines
MFR
Medford
$269 Roundtrip, just found
$269
Roundtrip
just found
Select American Airlines flight, departing Fri, Jan 16 from Des Moines to Medford, returning Mon, Jan 19, priced at $269 just found
United
Thu, Dec 11 - Mon, Dec 15
DSM
Des Moines
MFR
Medford
$274 Roundtrip, found 2 days ago
$274
Roundtrip
found 2 days ago
Select United flight, departing Thu, Dec 11 from Des Moines to Medford, returning Mon, Dec 15, priced at $274 found 2 days ago
Delta
Tue, Jan 13 - Thu, Jan 22
DSM
Des Moines
MFR
Medford
$279 Roundtrip, just found
$279
Roundtrip
just found
Select Delta flight, departing Tue, Jan 13 from Des Moines to Medford, returning Thu, Jan 22, priced at $279 just found
United
Sat, Nov 15 - Thu, Nov 27
DSM
Des Moines
MFR
Medford
$285 Roundtrip, found 3 days ago
$285
Roundtrip
found 3 days ago
Select United flight, departing Sat, Nov 15 from Des Moines to Medford, returning Thu, Nov 27, priced at $285 found 3 days ago
United
Sat, Nov 15 - Thu, Nov 27
DSM
Des Moines
MFR
Medford
$290 Roundtrip, found 3 days ago
$290
Roundtrip
found 3 days ago
Select United flight, departing Sat, Nov 15 from Des Moines to Medford, returning Thu, Nov 27, priced at $290 found 3 days ago
United
Thu, Nov 13 - Tue, Nov 18
DSM
Des Moines
MFR
Medford
$294 Roundtrip, found 3 days ago
$294
Roundtrip
found 3 days ago
Select United flight, departing Thu, Nov 13 from Des Moines to Medford, returning Tue, Nov 18, priced at $294 found 3 days ago
United
Thu, Dec 11 - Mon, Dec 15
DSM
Des Moines
MFR
Medford
$297 Roundtrip, found 2 days ago
$297
Roundtrip
found 2 days ago
Select United flight, departing Thu, Dec 11 from Des Moines to Medford, returning Mon, Dec 15, priced at $297 found 2 days ago
United
Thu, Apr 23 - Mon, Apr 27
DSM
Des Moines
MFR
Medford
$298 Roundtrip, found 2 days ago
$298
Roundtrip
found 2 days ago
Select United flight, departing Thu, Apr 23 from Des Moines to Medford, returning Mon, Apr 27, priced at $298 found 2 days ago
Delta
Thu, Feb 5 - Tue, Feb 24
DSM
Des Moines
MFR
Medford
$304 Roundtrip, found 1 day ago
$304
Roundtrip
found 1 day ago
Select Delta flight, departing Thu, Feb 5 from Des Moines to Medford, returning Tue, Feb 24, priced at $304 found 1 day ago
Alaska Airlines
Sat, Feb 14 - Sun, Feb 15
DSM
Des Moines
MFR
Medford
$359 Roundtrip, just found
$359
Roundtrip
just found
Select Alaska Airlines flight, departing Sat, Feb 14 from Des Moines to Medford, returning Sun, Feb 15, priced at $359 just found

Find the cheapest month to fly from Des Moines (DSM) to Medford (MFR)

October is typically the cheapest month to fly

From $268 - $628 per traveler.

Alternative airports near Medford

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Rogue Valley Intl. MFR. Cheapest and Closest option available. Average driving time to city center is 6 minutes. Flights from $364
MFR
Rogue Valley Intl.
CheapestClosest
Average driving time to city center6 min
Flights from $364

Frequently asked questions

How much does a flight from Des Moines Intl. Airport (DSM) to Rogue Valley Intl. Airport (MFR) cost?
Get a cheap one-way flight from $206 or cheap return flight from $269 from Des Moines Intl. Airport (DSM) to Rogue Valley Intl. Airport (MFR) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Des Moines Intl. Airport (DSM) to Rogue Valley Intl. Airport (MFR)?
Planning your trip for January can help you save, as it's the cheapest month for flights between DSM and MFR. You'll usually find the lowest fares during the off-season.
What is the cheapest airline that flies from Des Moines Intl. Airport (DSM) to Rogue Valley Intl. Airport (MFR)?
Use the filters on Expedia to compare different airlines and find the cheapest carrier that'll take you from DSM to MFR. Then, sort your results by "Price (lowest to highest)" to score a great deal.
How many flights per day from Des Moines Intl. Airport (DSM) to Rogue Valley Intl. Airport (MFR)?
You'll need to take a flight with a layover when traveling from Des Moines Intl. Airport (DSM) to Rogue Valley Intl. Airport (MFR). Direct flights don't operate daily on this route. However, just filter your search to include one or two stops to discover the best option for your trip.
What day of the week has the most flights from DSM to MFR?
You'll typically find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can change from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Des Moines Intl. Airport (DSM) to Rogue Valley Intl. Airport (MFR)?
Choose a flight from Des Moines Intl. Airport (DSM) to Rogue Valley Intl. Airport (MFR) that leaves before 3 PM to reduce the likelihood of delays. Departures after this hour are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Des Moines Intl. Airport (DSM) to Rogue Valley Intl. Airport (MFR) last-minute?
Booking your plane ticket from DSM to MFR right before your getaway is usually more expensive. But if you're flexible with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a DSM to MFR flight and hotel package?
Compared with arranging flights and hotels separately, booking a DSM to MFR flight and hotel package with Expedia could lead to significant savings. Better still, having everything in one convenient place takes the hassle out of planning your trip. Just secure your flights and choose from our wide range of hotels, then customize your trip with extras like activities, tours and car rentals.
Can I cancel or change the date of my flight from Des Moines Intl. Airport (DSM) to Rogue Valley Intl. Airport (MFR)?
In most cases, you're able to reschedule or cancel your DSM to MFR flight. However, additional charges may apply, especially if your booking was made more than 24 hours ago. Double-check your itinerary for the airline's fees and rules on flight changes, or if you'd like further information, visit our Customer Service portal.

Travel information

Origin airport
Des Moines Intl.
Destination airport
Rogue Valley Intl.
Airlines serving
Alaska Airlines, American Airlines, Delta, United
Roundtrip price
$268
Distance
1495 mi

Book with confidence

Des Moines to Medford Flights

The cheapest times to fly from Des Moines to Medford

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Des Moines to Medford are during the month of January. You can find some of the cheapest flights from Des Moines to Medford with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Des Moines to Medford

Sunday is one of the best days to book for cheap flights from Des Moines to Medford: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Des Moines to Medford

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Des Moines to Medford in 2025. You can also book with separate airlines for your outbound and return journeys, from $206 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Des Moines to Medford flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Des Moines to Medford airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Des Moines to Medford Flights

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*Available to One Key members.