$79 Cheap Flights from Des Moines (DSM) to Phoenix (PHX)

View $79 flight on Sat, Oct 18, 2025Opens in a new window

Popular airlines from Des Moines International Airport (DSM) to Phoenix Sky Harbor Intl. Airport (PHX)

  • Plan, book, fly with confidence

  • trending down icon
    Be in the know
    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon
    Book smarter
    Save up to 30% on select hotels after you book a flight*
  • one key icon
    Earn twice
    Earn your airline miles on top of our OneKeyCash
    Learn about One Key

Cheap Flights from Des Moines to Phoenix (DSM-PHX)

Prices were available within the past 7 days and start at $79 for one-way flights and $157 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Southwest Airlines
Wed, Oct 15 - Mon, Oct 20
DSM
Des Moines
PHX
Phoenix
$157 Roundtrip, found 13 hours ago
$157
Roundtrip
found 13 hours ago
Select Southwest Airlines flight, departing Wed, Oct 15 from Des Moines to Phoenix, returning Mon, Oct 20, priced at $157 found 13 hours ago
Southwest Airlines
Sat, Oct 18 - Sat, Nov 1
DSM
Des Moines
PHX
Phoenix
$167 Roundtrip, found 1 hour ago
$167
Roundtrip
found 1 hour ago
Select Southwest Airlines flight, departing Sat, Oct 18 from Des Moines to Phoenix, returning Sat, Nov 1, priced at $167 found 1 hour ago
Southwest Airlines
Sat, Sep 27 - Mon, Oct 6
DSM
Des Moines
PHX
Phoenix
$172 Roundtrip, found 7 hours ago
$172
Roundtrip
found 7 hours ago
Select Southwest Airlines flight, departing Sat, Sep 27 from Des Moines to Phoenix, returning Mon, Oct 6, priced at $172 found 7 hours ago
Southwest Airlines
Sat, Oct 18 - Sat, Nov 1
DSM
Des Moines
PHX
Phoenix
$176 Roundtrip, found 1 hour ago
$176
Roundtrip
found 1 hour ago
Select Southwest Airlines flight, departing Sat, Oct 18 from Des Moines to Phoenix, returning Sat, Nov 1, priced at $176 found 1 hour ago
Southwest Airlines
Wed, Oct 15 - Wed, Oct 22
DSM
Des Moines
PHX
Phoenix
$181 Roundtrip, found 2 days ago
$181
Roundtrip
found 2 days ago
Select Southwest Airlines flight, departing Wed, Oct 15 from Des Moines to Phoenix, returning Wed, Oct 22, priced at $181 found 2 days ago
Frontier Airlines
Wed, Oct 15 - Wed, Oct 22
DSM
Des Moines
PHX
Phoenix
$185 Roundtrip, found 20 hours ago
$185
Roundtrip
found 20 hours ago
Select Frontier Airlines flight, departing Wed, Oct 15 from Des Moines to Phoenix, returning Wed, Oct 22, priced at $185 found 20 hours ago
Southwest Airlines
Sat, Aug 23 - Mon, Aug 25
DSM
Des Moines
PHX
Phoenix
$187 Roundtrip, found 11 hours ago
$187
Roundtrip
found 11 hours ago
Select Southwest Airlines flight, departing Sat, Aug 23 from Des Moines to Phoenix, returning Mon, Aug 25, priced at $187 found 11 hours ago
American Airlines
Wed, Jul 16 - Wed, Jul 23
DSM
Des Moines
PHX
Phoenix
$234 Roundtrip, found 10 hours ago
$234
Roundtrip
found 10 hours ago
Select American Airlines flight, departing Wed, Jul 16 from Des Moines to Phoenix, returning Wed, Jul 23, priced at $234 found 10 hours ago
Delta
Wed, Jul 23 - Sat, Jul 26
DSM
Des Moines
PHX
Phoenix
$237 Roundtrip, found 20 hours ago
$237
Roundtrip
found 20 hours ago
Select Delta flight, departing Wed, Jul 23 from Des Moines to Phoenix, returning Sat, Jul 26, priced at $237 found 20 hours ago
United
Sat, Aug 30 - Sun, Aug 31
DSM
Des Moines
PHX
Phoenix
$271 Roundtrip, found 1 hour ago
$271
Roundtrip
found 1 hour ago
Select United flight, departing Sat, Aug 30 from Des Moines to Phoenix, returning Sun, Aug 31, priced at $271 found 1 hour ago

Find the cheapest month to fly from Des Moines (DSM) to Phoenix (PHX)

September is typically the cheapest month to fly

From $110 - $245 per traveler.

Graph displaying average flight prices per month

Flights from Des Moines (DSM) to Phoenix (PHX)
Origin airport
Des Moines Intl.
Destination airport
Sky Harbor Intl.
Airlines serving
Alaska Airlines, American Airlines, Delta, Frontier Airlines, Southwest Airlines, United
Roundtrip price
$157
Distance
1148 mi
Average flight time
1 hour 2 mins

Des Moines to Phoenix Flights

The cheapest times to fly from Des Moines to Phoenix

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Des Moines to Phoenix are during the month of October. You can find some of the cheapest flights from Des Moines to Phoenix with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Des Moines to Phoenix

Sunday is one of the best days to book for cheap flights from Des Moines to Phoenix: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Des Moines to Phoenix

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Des Moines to Phoenix in 2025. You can also book with separate airlines for your outbound and return journeys, from $79 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Des Moines to Phoenix flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Des Moines to Phoenix airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Des Moines Intl. Airport (DSM) to Sky Harbor Intl. Airport (PHX) cost?
You can book cheap return flights starting from $234 from Des Moines Intl. Airport (DSM) to Sky Harbor Intl. Airport (PHX). This information is based on the cheapest price found on Expedia for this return journey departing within the next three months. This airfare is for a American Airlines flight leaving DSM on July 22 2025 and touching down at PHX. The price was last updated on July 1 2025 and has not changed since.
What is the cheapest month to fly from DSM to PHX?
The cheapest flights from DSM to PHX are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
Which airlines fly direct from Des Moines Intl. Airport (DSM) to Sky Harbor Intl. Airport (PHX)?
Fly directly from Des Moines Intl. Airport (DSM) to Sky Harbor Intl. Airport (PHX) on an American Airlines flight.
What is the cheapest airline that flies from DSM to PHX?
Right now, the cheapest airline operating one-way flights from DSM to PHX is American Airlines. You can take off on this route from $149. This fare is based on the lowest price found on Expedia departing within the next three months. The flight takes off from DSM on September 8 2025. Prices were last updated on July 1 2025 and have not changed since.
How many flights per day from Des Moines Intl. Airport (DSM) to Sky Harbor Intl. Airport (PHX)?
Daily, an average of 3 direct flights operate from Des Moines Intl. Airport (DSM) to Sky Harbor Intl. Airport (PHX). Pick the departure time that works for you.
What are the most popular departure times for flights from Des Moines Intl. Airport (DSM) to Sky Harbor Intl. Airport (PHX)?
Flights between DSM and PHX are busiest at 5 AM. If you're after a quieter trip and possibly cheaper prices, choose a time when demand is lower.
What day of the week has the most flights from DSM to PHX?
Thursday offers the most flights from Des Moines Intl. Airport (DSM) to Sky Harbor Intl. Airport (PHX). Consider traveling on this day and you'll have the best chance of finding a departure that fits your itinerary.
What is the earliest flight from Des Moines Intl. Airport (DSM) to Sky Harbor Intl. Airport (PHX)?
Des Moines Intl. Airport (DSM)'s earliest flight to Sky Harbor Intl. Airport (PHX) leaves at approximately 5:00AM UTC-6. With a flight time of 3h 26m, you'll land at around 7:26AM UTC-7.
How long does it take to fly from Des Moines Intl. Airport (DSM) to Sky Harbor Intl. Airport (PHX)?
Flights from DSM to PHX have an average travel time of 3 hours and 20 minutes. The total distance between the two is 1,150 mi.
What airline has the least delays from DSM to PHX?
Southwest Airlines has the strongest track record for on-time direct flights from Des Moines Intl. Airport (DSM) to Sky Harbor Intl. Airport (PHX), with an on-time score of 87%. Use the Expedia App to see your flight schedule before you head off and get real-time updates about any changes.
What is the best time to fly from Des Moines Intl. Airport (DSM) to Sky Harbor Intl. Airport (PHX)?
Opt for a flight from Des Moines Intl. Airport (DSM) to Sky Harbor Intl. Airport (PHX) that leaves before 3 PM to reduce the risk of cancellations. Later departures have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for Phoenix from Des Moines Intl. Airport (DSM)?
If you're departing on a direct flight from Des Moines Intl. Airport (DSM) to Phoenix, you can arrive at either Sky Harbor Intl. Airport (PHX) or Phoenix - Mesa Gateway Airport (AZA).
Is it cheaper to buy a plane ticket from Des Moines Intl. Airport (DSM) to Sky Harbor Intl. Airport (PHX) last-minute?
Booking your ticket from DSM to PHX just before your trip is generally more expensive. But if you're flexible with your schedule, you could score a cheap last-minute fare.
Is it cheaper to book a DSM to PHX flight and hotel package?
Securing a DSM to PHX flight and hotel package is generally cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your travels all in one place. Pick from our wide range of accommodations and then add car rentals, activities and flights to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Des Moines Intl. Airport (DSM) to Sky Harbor Intl. Airport (PHX)?
You can usually cancel or reschedule your DSM to PHX flight. However, if it's been more than 24 hours since booking, additional fees may apply. Refer to your airline's policies in your itinerary to see what changes are allowed and whether any costs are involved. You'll also find further details on our Customer Service portal.

Explore a world of travel with Expedia

*Available to One Key members.