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$169 Cheap Flights from Detroit (DTW) to Greenville (GSP)

View $169 flight on Tue, Oct 6, 2026Opens in a new window

Popular airlines from Detroit Metropolitan Wayne County Airport (DTW) to Greenville-Spartanburg Intl. Airport (GSP)

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Cheap Flights from Detroit to Greenville (DTW-GSP)

Prices were available within the past 7 days and start at $169 for one-way flights and $329 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Southwest Airlines
Sat, Oct 24 - Wed, Oct 28
DTW
Detroit
GSP
Greenville
$329 Roundtrip, found 6 hours ago
$329
Roundtrip
found 6 hours ago
Select Southwest Airlines flight, departing Sat, Oct 24 from Detroit to Greenville, returning Wed, Oct 28, priced at $329 found 6 hours ago
Southwest Airlines
Sat, Oct 24 - Wed, Oct 28
DTW
Detroit
GSP
Greenville
$337 Roundtrip, found 6 hours ago
$337
Roundtrip
found 6 hours ago
Select Southwest Airlines flight, departing Sat, Oct 24 from Detroit to Greenville, returning Wed, Oct 28, priced at $337 found 6 hours ago
Southwest Airlines
Thu, Oct 29 - Sat, Oct 31
DTW
Detroit
GSP
Greenville
$338 Roundtrip, found 5 hours ago
$338
Roundtrip
found 5 hours ago
Select Southwest Airlines flight, departing Thu, Oct 29 from Detroit to Greenville, returning Sat, Oct 31, priced at $338 found 5 hours ago
Southwest Airlines
Wed, Nov 11 - Mon, Nov 16
DTW
Detroit
GSP
Greenville
$345 Roundtrip, found 17 hours ago
$345
Roundtrip
found 17 hours ago
Select Southwest Airlines flight, departing Wed, Nov 11 from Detroit to Greenville, returning Mon, Nov 16, priced at $345 found 17 hours ago
Southwest Airlines
Thu, Nov 26 - Thu, Dec 3
DTW
Detroit
GSP
Greenville
$351 Roundtrip, found 7 hours ago
$351
Roundtrip
found 7 hours ago
Select Southwest Airlines flight, departing Thu, Nov 26 from Detroit to Greenville, returning Thu, Dec 3, priced at $351 found 7 hours ago
Southwest Airlines
Wed, Nov 11 - Mon, Nov 16
DTW
Detroit
GSP
Greenville
$354 Roundtrip, found 17 hours ago
$354
Roundtrip
found 17 hours ago
Select Southwest Airlines flight, departing Wed, Nov 11 from Detroit to Greenville, returning Mon, Nov 16, priced at $354 found 17 hours ago
Southwest Airlines
Tue, Oct 27 - Fri, Oct 30
DTW
Detroit
GSP
Greenville
$357 Roundtrip, found 6 hours ago
$357
Roundtrip
found 6 hours ago
Select Southwest Airlines flight, departing Tue, Oct 27 from Detroit to Greenville, returning Fri, Oct 30, priced at $357 found 6 hours ago
Delta
Mon, Mar 29 - Sun, Apr 4
DTW
Detroit
GSP
Greenville
$443 Roundtrip, just found
$443
Roundtrip
just found
Select Delta flight, departing Mon, Mar 29 from Detroit to Greenville, returning Sun, Apr 4, priced at $443 just found
United
Wed, Oct 14 - Sun, Oct 18
DTW
Detroit
GSP
Greenville
$461 Roundtrip, found 5 hours ago
$461
Roundtrip
found 5 hours ago
Select United flight, departing Wed, Oct 14 from Detroit to Greenville, returning Sun, Oct 18, priced at $461 found 5 hours ago
American Airlines
Thu, Oct 29 - Sat, Oct 31
DTW
Detroit
GSP
Greenville
$463 Roundtrip, found 5 hours ago
$463
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Thu, Oct 29 from Detroit to Greenville, returning Sat, Oct 31, priced at $463 found 5 hours ago

Alternative airports near Greenville

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Greenville-Spartanburg Intl. GSP. Cheapest option available. Average driving time to city center is 18 minutes. Flights from $430
GSP
Greenville-Spartanburg Intl.
Cheapest
Average driving time to city center18 min
Flights from $430

Find the cheapest month to fly from Detroit (DTW) to Greenville (GSP)

October is typically the cheapest month to fly

From $270 - $409 per traveler.

What you need to know for your flight from Detroit Metropolitan Wayne County to Greenville-Spartanburg Intl.

Detroit (DTW) to Greenville (GSP) at a glance

Explore a range of airlines offering flights from Detroit Metropolitan Wayne County Airport (DTW) to Greenville-Spartanburg International Airport (GSP) on this domestic short-haul route. You can compare options from both full-service and low-cost carriers to uncover the cheapest flights to Greenville that align with your budget and travel schedule. With several weekly flights from Detroit, you’re sure to find an itinerary that perfectly fits your plans as you discover the attractions and neighborhoods of Greenville.

  • Fastest flight duration: around 1h 45m non-stop
  • Route distance: roughly 500 miles (800 km)
  • Flights per week: around 11 departures on average
  • Typical fares (one-way): economy tickets often range from $165–$550, depending on seasonality and how far ahead you book

Flights from Detroit Metropolitan Wayne County Airport (DTW) to Greenville-Spartanburg International Airport (GSP)

Based on the latest traveler bookings, here are the top airlines favored for flights from Detroit to Greenville, particularly for non-stop and one-stop options. Popular layover points include Baltimore Washington International Thurgood Marshall Airport (BWI), with an average layover of about 1 hour and 15 minutes; Charlotte-Douglas International Airport (CLT), offering a 1-hour layover; and Hartsfield-Jackson Atlanta International Airport (ATL), which also has a typical layover of around 1 hour and 15 minutes. These choices allow you to effectively balance price, total travel time, and cabin class while planning your itinerary.

  • Delta: As a premier full-service airline, Delta provides both non-stop and one-stop options, with one-way ticket prices generally ranging from $200 to $585. This airline operates approximately 72% of the departures on this route, boasting a typical non-stop travel duration of 1 hour and 45 minutes.
  • Southwest Airlines: Known for its budget-friendly approach, Southwest Airlines offers one-stop flights with fares typically between $165 and $395. This carrier represents about 16% of the route’s departures, featuring an in-flight duration of 3 hours and a total travel time of around 4 hours and 15 minutes, including layovers.
  • American Airlines: Another full-service option, American Airlines provides one-stop services with one-way fares generally falling between $165 and $510. This airline accounts for roughly 11% of departures on this route, with an in-flight time of 3 hours and a total journey time of about 4 hours and 15 minutes, factoring in layovers.

Travelers flying from Detroit to Greenville have the option to upgrade their experience, with Delta offering both first class and premium economy class, while American Airlines provides first class service.

Best time to fly from Detroit (DTW) to Greenville (GSP)

The most popular months for travelers flying from Detroit to Greenville are February, March, and April, when peak temperatures in Greenville reach up to 59.9°F in April. If you prefer quieter travel, consider November, the least busy and relatively cheaper time to visit with fewer crowds and temperatures around 51.1°F. For better deals, June usually offers the lowest average one-way fare around $285. Flight availability peaks in May, with approximately 15 flights per week, making it easier to find convenient departure times. January and September have the fewest flights, with approximately 9 flights per week.

  • Cheapest time to fly: June usually offers good deals with average one-way fare around $285, roughly 15% cheaper than the yearly average.
  • More budget-friendly months to fly: November and October typically offer average one-way fares of around $311.
  • Most flight options: May has the highest number of flights from Detroit to Greenville, with approximately 15 flights per week, giving you more flexibility in scheduling your trip.
calendar iconMonthtemperature iconTemperaturecrowd level iconDemandflights iconWeekly Flightsprice iconAverage one-way Fare
January41.4°F (5.2°C)Average9$364
February45.3°F (7.4°C)High10$342
March51.8°F (11.0°C)High11$350
April59.9°F (15.5°C)High11$357
May68.4°F (20.2°C)Average15$315
June76.1°F (24.5°C)Average10$285
July79.5°F (26.4°C)Low10$386
August77.5°F (25.3°C)Average12$364
September72.3°F (22.4°C)Low9$341
October61.9°F (16.6°C)Average12$313
November51.1°F (10.6°C)Low12$309
December45.3°F (7.4°C)Average11$318

*Average one-way fare is based on Expedia flight booking data from January 2025 to April 2026 for the specified route and travel class and may change depending on availability, dates, and demand.

Alternative routes from Detroit (DTW) to Greenville (GSP)

  • Detroit to Greenville (DTW-GMU): Located approximately 8 miles from Greenville-Spartanburg International Airport (GSP), Greenville Downtown Airport (GMU) serves as a convenient option for travelers.
  • Detroit to Spartanburg (DTW-SPA): Spartanburg Downtown Memorial Airport (SPA) is roughly 15 miles from Greenville-Spartanburg International Airport (GSP), making it a viable choice for passengers.

How to find the best prices for flights from Detroit (DTW) to Greenville (GSP)

Getting some of the best deals on flights from Detroit to Greenville is all about timing and flexibility. Here are some key tips to help you save:

  1. Best times to book and fly: cheaper fares are usually found when booking 2-8 weeks in advance, which is also when most travelers make their reservations. Morning departures (5am-12pm) tend to offer lower prices, while afternoon flights (12pm-6pm) are more popular. Additionally, flying on Tuesday generally results in cheaper prices, although Friday is the most popular day for travel.
  2. Set up price alerts: stay updated on price changes by using Expedia's Price Tracker. Receive alerts when fares drop for your selected route.
  3. Bundle and save: bundle your flight and hotel to save on Expedia, or unlock a hotel deal after booking your flight.* Find Greenville hotel and flight deals.
  4. Compare flight options: use Expedia's search tool to compare airlines, routes, direct vs. non-direct flights, and flight times. You can also sort by price to find the most affordable options.
  5. Stay flexible with dates: being open to different travel days can sometimes help you find better prices on flights and hotels.
  6. Think about luggage: nowadays, it's important to check the airline's baggage policies to find the best value. That may be paying for an additional carry-on bag or booking a ticket with checked luggage included. Either way, double-check your allowance before confirming your booking to avoid excess baggage fees at the airport.

*Members only. Savings vary and are not available on all bundles. Select hotels.

Arriving at Greenville-Spartanburg International Airport from Detroit Metropolitan Wayne County Airport

Greenville welcomes travelers from Detroit with a range of transport options based on price, convenience, and proximity. Greenville city center is approximately a 20-minute drive (covering about 16 miles) from Greenville-Spartanburg International Airport, depending on traffic. Here's how to reach Greenville efficiently:

  • Hotel transfer: Transfers offer a convenient way to reach your hotel in Greenville, with options including free hotel shuttles and private rides, which can be arranged in advance with your hotel.
  • Car rental: Renting a car from Greenville-Spartanburg International Airport is a great option if you plan to explore and sightsee beyond the city. Browse cheap car rentals at Greenville-Spartanburg International Airport on Expedia.
  • Taxi/ride-hailing: Taxis and ride-hailing services may be available from designated pickup areas outside the terminal, check locally on arrival.

Frequently asked questions

How much does a flight from Detroit, MI (DTW-Detroit Metropolitan Wayne County) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) cost?
You can find cheap one-way flights from $169 and cheap return flights from $329 Detroit, MI (DTW-Detroit Metropolitan Wayne County) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) with Expedia. One-way flights typically cost between $321 and $969, and return flights often range between $458 and $1625. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Detroit, MI (DTW-Detroit Metropolitan Wayne County) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from Detroit, MI (DTW-Detroit Metropolitan Wayne County) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
September is the cheapest month to fly from Detroit (DTW) to Greenville (GSP), with average return fares around $448. This price is about 17% lower than the average throughout the year, as September often experiences a lull in travel after the summer peak. Other budget-friendly months to consider are May and October.*Averages based on flights available on Expedia in the last year.
Which airlines fly direct from Detroit, MI (DTW-Detroit Metropolitan Wayne County) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
Delta operates around 24 direct flights from DTW to GSP every week.
What is the cheapest airline that flies from Detroit, MI (DTW-Detroit Metropolitan Wayne County) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
Delta is one of the cheapest airlines offering nonstop flights from Detroit Metropolitan Wayne County (DTW) to Greenville-Spartanburg Intl. (GSP), with round-trip tickets starting from around $520. This option provides a direct route, making your travel experience smooth and efficient. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.*Prices based on flights available on Expedia in the last year.
How do I find cheap flights from Detroit, MI (DTW-Detroit Metropolitan Wayne County) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
To find a cheap flight from Detroit, MI (DTW-Detroit Metropolitan Wayne County) to Greenville, SC (GSP-Greenville-Spartanburg Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best airline to fly with from Detroit, MI (DTW-Detroit Metropolitan Wayne County) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
The best airline to fly with from Detroit, MI (DTW) to Greenville, SC (GSP) will differ from traveler to traveler. If you like to fly early, Delta offers early morning flights. If price is the most important factor, Delta typically offers the lowest fares. Delta also offers the most daily flights from DTW to GSP, which is great if flexibility is what you value most. The best carrier for this journey could also be the one you have a loyalty membership with, as flying with that airline or another airline within the same alliance could help you collect points or enjoy lounge access.
What is the best time to fly from Detroit, MI (DTW-Detroit Metropolitan Wayne County) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
The best months to fly from Detroit, MI (DTW) to Greenville, SC (GSP) are May and September. In May, you can find return flights for around $448, while September also offers competitive pricing. These months are ideal as they provide a good balance of pleasant weather and reasonable fares, ensuring a great travel experience. This information is based on booking data from the past year.*Prices based on flights available on Expedia in the last year.
How many flights per day from Detroit, MI (DTW-Detroit Metropolitan Wayne County) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
There are approximately 3 nonstop flights per day from Detroit Metropolitan Wayne County (DTW) to Greenville-Spartanburg Intl. (GSP). For more options, look at flights that include layovers.
What is the earliest flight from Detroit, MI (DTW-Detroit Metropolitan Wayne County) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
Sort flights by "Departure (earliest)" on Expedia to find the earliest flight from DTW to GSP. To compare more early flights, use the "Early Morning" and "Morning" filters in your search.
What are the most popular departure times for flights from Detroit, MI (DTW-Detroit Metropolitan Wayne County) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
The most popular departure times for flights from Detroit, MI (DTW) to Greenville, SC (GSP) are in the early morning, from 6am to 9am. About 29% of passengers prefer this time window. Many major carriers, including American Airlines, Delta, and United Airlines, offer flights during this window. This timing is popular because it allows you to arrive in Greenville with plenty of time to enjoy the day.
How long does it take to fly from Detroit, MI (DTW-Detroit Metropolitan Wayne County) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
A nonstop flight from DTW to GSP typically takes around 1 hour 50 minutes, covering approximately 510 miles. Connecting flights on this route usually add 2 hours 30 minutes to your travel time. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Detroit, MI (DTW-Detroit Metropolitan Wayne County) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
You can fly first class between DTW and GSP. First class cabins are available on:

  • American Airlines
  • United Airlines
  • Delta Air Lines

How do I earn miles on a Detroit, MI (DTW-Detroit Metropolitan Wayne County) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) flight with Expedia?
It's easy to earn miles on a Detroit, MI (DTW-Detroit Metropolitan Wayne County) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Greenville from Detroit Metropolitan Wayne County (DTW)?
When traveling from Detroit Metropolitan Wayne County (DTW) to Greenville, you can fly into Pitt-Greenville (PGV) and Greenville-Spartanburg Intl. (GSP). Some flights may connect through major hubs like Ronald Reagan Washington National (DCA), Dallas-Fort Worth Intl. (DFW), O'Hare Intl. (ORD) before reaching Greenville. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Detroit, MI (DTW-Detroit Metropolitan Wayne County) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) at the last minute?
Typically, booking a last minute flight from Detroit, MI (DTW-Detroit Metropolitan Wayne County) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Detroit, MI (DTW-Detroit Metropolitan Wayne County) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) flight and hotel package?
Securing a Detroit, MI (DTW-Detroit Metropolitan Wayne County) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Detroit, MI (DTW-Detroit Metropolitan Wayne County) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
If you booked your Detroit, MI (DTW-Detroit Metropolitan Wayne County) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Detroit Metropolitan Wayne County
Destination airport
Greenville-Spartanburg Intl.
Airlines serving
American Airlines, Delta, Southwest Airlines, United
Roundtrip price
$328
Distance
510 mi
Average flight time
1 hour 48 mins

Book with confidence

Detroit to Greenville Flights

The cheapest times to fly from Detroit to Greenville

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Detroit to Greenville are during the month of October. You can find some of the cheapest flights from Detroit to Greenville with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Detroit to Greenville

Sunday is one of the best days to book for cheap flights from Detroit to Greenville: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Detroit to Greenville

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Detroit to Greenville in 2026. You can also book with separate airlines for your outbound and return journeys, from $169 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Detroit to Greenville flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Detroit to Greenville airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Detroit to Greenville Flights

*Flight schedules are subject to change.

*Available to One Key members.

 

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