$117 Cheap Flights from Indianapolis (IND) to Greenville (GSP)
Popular airlines from Indianapolis Intl. Airport (IND) to Greenville-Spartanburg Intl. Airport (GSP)
American AirlinesAmerican Airlines
UnitedUnited
DeltaDelta
Southwest AirlinesSouthwest Airlines
Be in the knowGet alerts if flight prices drop or rise*
Book smarterSave up to 30% on select hotels after you book a flight*
Cheap Flights from Indianapolis to Greenville (IND-GSP)
Alternative airports near Greenville
Prices were available within the past 7 days. Prices and availability are subject to change.
Book with confidence
Indianapolis (IND) to Greenville (GSP) at a glance
Travel from Indianapolis (IND) to Greenville (GSP) with a range of airlines on this convenient domestic route. Discover options for cheap flights from Indianapolis and compare airfares to Greenville to find the itinerary that suits your budget and travel plans. With both full-service and low-cost carriers available, you can easily plan your journey as you look forward to exploring Greenville’s iconic attractions and vibrant neighborhoods. Check out key details for weekly flights from Indianapolis to make your travel arrangements hassle-free.
- Fastest flight duration: around 2h 45m in-flight, plus roughly 1h 15m layover with one stop
- Route distance: roughly 400 miles (645 km)
- Flights per week: around 11 departures on average
- Typical fares (one-way): economy tickets often range from $100–$380, depending on seasonality and how far ahead you book
Flights from Indianapolis International Airport (IND) to Greenville-Spartanburg International Airport (GSP)
Based on the latest traveler bookings, here are the top airlines favored for flights from Indianapolis to Greenville, particularly for their one-stop services. Popular layover points include Charlotte-Douglas International Airport (CLT), with a layover of about 1 hour and 15 minutes, Hartsfield-Jackson Atlanta International Airport (ATL), also approximately 1 hour and 15 minutes, and Nashville International Airport (BNA), which typically has a 1 hour and 30 minutes layover. These options allow you to balance price, total travel time, and cabin class for the best travel experience.
- American Airlines: This full-service airline provides one-stop travel options, with one-way ticket prices generally falling between $100 and $380. It represents about 46% of the flights on this route, featuring a flight duration of 2 hours and 45 minutes, and a total travel time of around 4 hours, including layover.
- Delta: Another full-service option, Delta offers one-stop services with one-way fares typically priced from $100 to $380. It accounts for roughly 35% of departures on this route, with a flight time of 2 hours and 45 minutes, and an overall journey time of about 4 hours, including layover.
- Southwest Airlines: This budget-friendly carrier provides one-stop service, with one-way fares usually ranging from $100 to $370. Southwest makes up approximately 11% of departures on this route, with an in-flight duration of 2 hours and 45 minutes and a total travel time of around 4 hours, including layover.
- United: Offering one-stop service, United is a full-service airline with one-way fares generally between $115 and $360. It constitutes about 8% of flights on this route, featuring a flight time of 2 hours and 45 minutes and an overall journey duration of nearly 4 hours, including layover.
Travelers flying from Indianapolis to Greenville can enhance their experience by upgrading their flight. American Airlines offers first class, while Delta provides both first class and premium economy service.
Best time to fly from Indianapolis (IND) to Greenville (GSP)
The most popular months for travelers flying from Indianapolis to Greenville are January, February, and April, when peak temperatures in Greenville reach up to 59.9°F in April. If you prefer quieter travel, consider June, the least busy and relatively cheaper time to visit with fewer crowds and temperatures around 76.1°F. For better deals, August usually offers the lowest average one-way fare around $190. Flight availability peaks in April, August, and November, with approximately 13 flights per week, making it easier to find convenient departure times.
- Cheapest time to fly: August usually offers good deals with average one-way fare around $190, roughly 12% cheaper than the yearly average.
- More budget-friendly months to fly: September and October typically offer average one-way fares roughly ranging from $191 to $204.
- Most flight options: April, August, and November have the highest number of flights from Indianapolis to Greenville, with approximately 13 flights per week, giving you more flexibility in scheduling your trip.
| Month | Temperature | Demand | Weekly Flights | Average one-way Fare |
| January | 41.4°F (5.2°C) | Moderately High | 12 | $222 |
| February | 45.3°F (7.4°C) | Moderately High | 11 | $225 |
| March | 51.8°F (11.0°C) | Average | 11 | $233 |
| April | 59.9°F (15.5°C) | Moderately High | 13 | $243 |
| May | 68.4°F (20.2°C) | Average | 12 | $211 |
| June | 76.1°F (24.5°C) | Moderately Low | 10 | $216 |
| July | 79.5°F (26.4°C) | Average | 12 | $214 |
| August | 77.5°F (25.3°C) | Average | 13 | $190 |
| September | 72.3°F (22.4°C) | Average | 10 | $191 |
| October | 61.9°F (16.6°C) | Average | 11 | $204 |
| November | 51.1°F (10.6°C) | Moderately Low | 13 | $234 |
| December | 45.3°F (7.4°C) | Moderately Low | 10 | $229 |
*Average one-way fare is based on Expedia flight booking data from January 2025 to April 2026 for the specified route and travel class and may change depending on availability, dates, and demand.
Alternative routes from Indianapolis (IND) to Greenville (GSP)
- Indianapolis to Greenville (IND-GMU): The Greenville Downtown Airport (GMU) is located approximately 8 miles from Greenville-Spartanburg International Airport (GSP).
- Indianapolis to Spartanburg (IND-SPA): Spartanburg Downtown Memorial Airport (SPA) lies around 15 miles from Greenville-Spartanburg International Airport (GSP).
How to find the best prices for flights from Indianapolis (IND) to Greenville (GSP)
Getting some of the best deals on flights from Indianapolis to Greenville is all about timing and flexibility. Here are some key tips to help you save:
- Best times to book and fly: cheaper fares are usually found when booking 2-8 weeks in advance, which aligns with when most travelers make their reservations. Morning departures, from 5 a.m. to 12 p.m., often feature lower prices and are the most favored flight times. Additionally, flying on Wednesday typically results in cheaper fares, while Thursday remains the most popular travel day.
- Set up price alerts: stay updated on price changes by using Expedia's Price Tracker. Receive alerts when fares drop for your selected route.
- Bundle and save: bundle your flight and hotel to save on Expedia, or unlock a hotel deal after booking your flight.* Find Greenville hotel and flight deals.
- Compare flight options: use Expedia's search tool to compare airlines, routes, direct vs. non-direct flights, and flight times. You can also sort by price to find the most affordable options.
- Stay flexible with dates: being open to different travel days can sometimes help you find better prices on flights and hotels.
- Think about luggage: nowadays, it's important to check the airline's baggage policies to find the best value. That may be paying for an additional carry-on bag or booking a ticket with checked luggage included. Either way, double-check your allowance before confirming your booking to avoid excess baggage fees at the airport.
*Members only. Savings vary and are not available on all bundles. Select hotels.
Arriving at Greenville-Spartanburg International Airport from Indianapolis International Airport
Greenville welcomes travelers from Indianapolis with a range of transport options based on price, convenience, and proximity. Greenville city center is approximately a 20-minute drive (covering about 16 miles) from Greenville-Spartanburg International Airport, depending on traffic. Here's how to reach Greenville efficiently:
- Hotel transfer: Transfers offer a convenient way to reach your hotel in Greenville, with options including free hotel shuttles and private rides, which can be arranged in advance with your hotel.
- Car rental: Renting a car from Greenville-Spartanburg International Airport is a great option if you plan to explore and sightsee beyond the city. Browse cheap car rentals at Greenville-Spartanburg International Airport on Expedia.
- Taxi/ride-hailing: Taxis and ride-hailing services may be available from designated pickup areas outside the terminal, check locally on arrival.
Indianapolis to Greenville Flights
The cheapest times to fly from Indianapolis to Greenville
On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Indianapolis to Greenville are during the month of February. You can find some of the cheapest flights from Indianapolis to Greenville with Expedia's search tool and vast selection of airlines.
The best time to book a flight from Indianapolis to Greenville
Sunday is one of the best days to book for cheap flights from Indianapolis to Greenville: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.
How to find cheap round-trip tickets from Indianapolis to Greenville
Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Indianapolis to Greenville in 2026. You can also book with separate airlines for your outbound and return journeys, from $117 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.
Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Indianapolis to Greenville flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.
You could also save big by booking one of Expedia's vacation packages. Bundling together your Indianapolis to Greenville airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.
*Terms apply.
Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.
Frequently Asked Questions
How much does a flight from Indianapolis, IN (IND-Indianapolis Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) cost?
You can find cheap one-way flights from $117 and cheap return flights $233 Indianapolis, IN (IND-Indianapolis Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) with Expedia. One-way flights typically cost between $128 and $569, and return flights often range between $298 and $1202. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Indianapolis, IN (IND-Indianapolis Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) ticket fares go up or down.
*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from Indianapolis, IN (IND-Indianapolis Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
September is the cheapest month to fly from Indianapolis, IN (IND) to Greenville, SC (GSP), with average round-trip fares around $297. This is about 21% lower than the average price throughout the year, as demand tends to decrease after the summer. Other budget-friendly months include January and February.
*Averages based on flights available on Expedia in the last year.
Which airlines fly direct from Indianapolis, IN (IND-Indianapolis Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
Enter IND to GSP and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
How do I find cheap flights from Indianapolis, IN (IND-Indianapolis Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
To find a cheap flight from Indianapolis, IN (IND-Indianapolis Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Indianapolis, IN (IND-Indianapolis Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
The best time to fly from Indianapolis (IND) to Greenville (GSP) is typically in September, when you can find return flights averaging around $297. This month is not only the cheapest but also popular for travel, making it a great time to enjoy good flight options and reasonable fares.
*Prices based on flights available on Expedia in the last year.
What is the earliest flight from Indianapolis, IN (IND-Indianapolis Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
The earliest flight from Indianapolis International Airport (IND) to Greenville-Spartanburg International Airport (GSP) typically departs at around 5:00 AM local time, operated by American Airlines. This is a seasonal service active in June, allowing you to maximize your time in South Carolina. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What are the most popular departure times for flights from Indianapolis, IN (IND-Indianapolis Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
The most popular departure times for flights from Indianapolis, IN (IND) to Greenville, SC (GSP) are in the early morning, from 6am to 9am. About 31% of passengers prefer this time window. Many major carriers, including American Airlines, Delta Air Lines, and United Airlines, offer flights during this window. This timing is popular because it allows you to start your day early and arrive in Greenville ready for your plans.
How long does it take to fly from Indianapolis, IN (IND-Indianapolis Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
Flying from IND to GSP with a connection usually takes about 4 hours 20 minutes, traveling roughly 402 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Indianapolis, IN (IND-Indianapolis Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
Select the "Business class" and "First class" filters when looking for IND to GSP flights on Expedia. This is the easiest way to compare prices, routes and flight times for your trip.
How do I earn miles on a Indianapolis, IN (IND-Indianapolis Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) flight with Expedia?
It's easy to earn miles on a Indianapolis, IN (IND-Indianapolis Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.
*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Greenville from Indianapolis Intl. (IND)?
From Indianapolis Intl. (IND), you can fly into Pitt-Greenville (PGV), Greenville-Spartanburg Intl. (GSP) and Mid Delta Regional (GLH) in Greenville. Some flights may connect through major hubs like Ronald Reagan Washington National (DCA), Dallas-Fort Worth Intl. (DFW), Miami Intl. (MIA) before reaching Greenville. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Indianapolis, IN (IND-Indianapolis Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) at the last minute?
Typically, booking a last minute flight from Indianapolis, IN (IND-Indianapolis Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Indianapolis, IN (IND-Indianapolis Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) flight and hotel package?
Securing a Indianapolis, IN (IND-Indianapolis Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Indianapolis, IN (IND-Indianapolis Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
If you booked your Indianapolis, IN (IND-Indianapolis Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.
Travel information
Origin airport | Indianapolis Intl. Airport |
|---|---|
Destination airport | Greenville-Spartanburg Intl. Airport |
Distance | 401 miles away |
Airlines serving | American Airlines, United, Delta, Southwest Airlines |
Popular airline | American Airlines |
Roundtrip price | $233 |