Popular airlines from Chicago Midway Airport (MDW) to Saint-Exupery Airport (LYS)
DeltaDelta
Air FranceAir France
KLMKLM
Cheap Flights from Chicago to Lyon (MDW-LYS)
Prices were available within the past 7 days and start at $487 for one-way flights and $615 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.
Frequently asked questions
Travel information
Origin airport | Midway Intl. |
|---|---|
Destination airport | Saint-Exupery |
Roundtrip price | $614 |
Distance | 4363 mi |
Book with confidence
Chicago to Lyon Flights
The cheapest times to fly from Chicago to Lyon
On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Chicago to Lyon are during the month of February. You can find some of the cheapest flights from Chicago to Lyon with Expedia's search tool and vast selection of airlines.
The best time to book a flight from Chicago to Lyon
Sunday is one of the best days to book for cheap flights from Chicago to Lyon: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.
How to find cheap round-trip tickets from Chicago to Lyon
Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Chicago to Lyon in 2025. You can also book with separate airlines for your outbound and return journeys, from $487 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.
Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Chicago to Lyon flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.
You could also save big by booking one of Expedia's vacation packages. Bundling together your Chicago to Lyon airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.
*Terms apply.
Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.
Explore a world of travel with Expedia
- Hotels near Lyon-Saint-Exupéry TGV Station
- Hotels near Dornon
- Colombier-Saugnieu Hotels
- Pusignan Hotels
- Apartments in Pusignan
- Saint-Bonnet-de-Mure Hotels
- B&B in Saint-Bonnet-de-Mure
- Genas Hotels
- Pet-friendly Hotels in Genas
- Meyzieu Hotels
- Hotels with Laundry Facilities in Meyzieu
- Chalets in Meyzieu
- Aparthotels in Meyzieu
- Chassieu Hotels
- B&B in Chassieu
- Hotels near Groupama Stadium
- Jonage Hotels
- Hotels near Eurexpo Lyon
- Hotels near Lyon Golf Club
- Cottages in Jons
- Jons Hotels
- Villas in Jons
- Chavanoz Hotels
- Saint-Priest Hotels
- Pet-friendly Hotels in Saint-Priest
- Golf Hotels in Saint-Priest
- Cheap Hotels in Saint-Priest
- Hotels near Le Grand Large
- Flights from Colombier-Saugnieu
- Flights to Saint-Priest
- Flights from Amsterdam (AMS) to Lyon (LYN)
- Flights from Beirut (BEY) to Lyon (LYN)
- Flights from Frankfurt (FRA) to Lyon (LYN)
- Flights from London (LHR) to Lyon (LYN)
- Flights from Rome (FCO) to Lyon (LYN)
- Flights from Nice (NCE) to Lyon (LYN)
- Flights from Rochester (ROC) to Lyon (LYN)
- Flights from Atlanta (ATL) to Lyon (LYN)
- Flights from Charlotte (CLT) to Lyon (LYN)
- Flights from Barcelona (BCN) to Lyon (LYN)
- Flights from Chicago (ORD) to Lyon (LYN)
- Flights from Tampa (TPA) to Lyon (LYN)
- Flights from Dubai (DXB) to Lyon (LYN)
- Flights from San Francisco (SFO) to Lyon (LYN)
- Flights from Karlsruhe Baden-Baden (FKB) to Lyon (LYN)
- Flights from Paris (CDG) to Lyon (LYN)
- Flights from Toulouse (TLS) to Lyon (LYN)
- Flights from Hartford (BDL) to Lyon (LYN)
- Flights from Madrid (MAD) to Lyon (LYN)
- Flights from Seattle (SEA) to Lyon (LYN)
- Flights from Washington (IAD) to Lyon (LYN)
- Flights from Honolulu (HNL) to Lyon (LYN)
- Flights from Fort Lauderdale (FLL) to Lyon (LYN)
- Flights from Berlin (BER) to Lyon (LYN)
- Flights from Manila (MNL) to Lyon (LYN)
- Flights from Denver (DEN) to Lyon (LYN)
- Flights from Boston (BOS) to Lyon (LYN)
- Flights from Los Angeles (LAX) to Lyon (LYN)
- Flights from Tel Aviv (TLV) to Lyon (LYN)
- Flights from Columbus (CMH) to Lyon (LYN)
- Flights from Munich (MUC) to Lyon (LYN)
- Flights from Rouen (URO) to Lyon (LYN)
- Flights from Belgrade (BEG) to Lyon (LYN)
- Flights from East Midlands (EMA) to Lyon (LYN)
- Flights from São Paulo (GRU) to Lyon (LYN)
- Flights from Zürich (ZRH) to Lyon (LYN)
- Flights from Dublin (DUB) to Lyon (LYN)
- Flights from Brussels (BRU) to Lyon (LYN)
- Flights from New York (JFK) to Lyon (LYN)
- Visit Colombier-Saugnieu
- Visit Pusignan
- Visit Saint-Laurent-de-Mure
- Visit Montcul
- Visit Saint-Bonnet-de-Mure
- Visit Genas
- Visit Satolas-et-Bonce
- Satolas-et-Bonce Vacations
- Visit Charvieu-Chavagneux
- Charvieu-Chavagneux Vacations
- Visit Grenay
- Visit Jameyzieu
- Visit Meyzieu
- Visit Chesnes
- Visit Chassieu
- Chassieu Vacations
- Visit Pont-de-Cheruy
- Visit Jonage
- Visit Tignieu-Jameyzieu
- Visit Saint-Pierre-de-Chandieu
- Eurexpo Lyon
- Visit Jons
- Visit Saint-Priest
- Le Grand Large