$2,196 Cheap Flights from Portland (PDX) to São Tomé Island (TMS)

View $2,196 flight on Wed, Jul 15, 2026Opens in a new window

Popular airlines from Portland International Airport (PDX) to São Tomé Island (TMS-São Tomé Intl.)

Cheap Flights from Portland to São Tomé Island (PDX-TMS)

Prices were available within the past 7 days and start at $2,196 for one-way flights and $3,897 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

TAP Portugal
Wed, Jul 15 - Fri, Jul 31
PDX
Portland
TMS
São Tomé Island
$3,897 Roundtrip, found 2 days ago
$3,897
Roundtrip
found 2 days ago
Select TAP Portugal flight, departing Wed, Jul 15 from Portland to São Tomé Island, returning Fri, Jul 31, priced at $3,897 found 2 days ago
TAP Portugal
Wed, Jul 15 - Fri, Jul 31
PDX
Portland
TMS
São Tomé Island
$3,907 Roundtrip, found 2 days ago
$3,907
Roundtrip
found 2 days ago
Select TAP Portugal flight, departing Wed, Jul 15 from Portland to São Tomé Island, returning Fri, Jul 31, priced at $3,907 found 2 days ago
TAP Portugal
Wed, Jul 15 - Fri, Jul 31
PDX
Portland
TMS
São Tomé Island
$3,946 Roundtrip, found 2 days ago
$3,946
Roundtrip
found 2 days ago
Select TAP Portugal flight, departing Wed, Jul 15 from Portland to São Tomé Island, returning Fri, Jul 31, priced at $3,946 found 2 days ago
TAP Portugal
Wed, Jul 15 - Fri, Jul 31
PDX
Portland
TMS
São Tomé Island
$3,952 Roundtrip, found 2 days ago
$3,952
Roundtrip
found 2 days ago
Select TAP Portugal flight, departing Wed, Jul 15 from Portland to São Tomé Island, returning Fri, Jul 31, priced at $3,952 found 2 days ago
TAP Portugal
Wed, Jul 15 - Fri, Jul 31
PDX
Portland
TMS
São Tomé Island
$3,956 Roundtrip, found 2 days ago
$3,956
Roundtrip
found 2 days ago
Select TAP Portugal flight, departing Wed, Jul 15 from Portland to São Tomé Island, returning Fri, Jul 31, priced at $3,956 found 2 days ago
TAP Portugal
Wed, Jul 15 - Fri, Jul 31
PDX
Portland
TMS
São Tomé Island
$3,997 Roundtrip, found 2 days ago
$3,997
Roundtrip
found 2 days ago
Select TAP Portugal flight, departing Wed, Jul 15 from Portland to São Tomé Island, returning Fri, Jul 31, priced at $3,997 found 2 days ago
TAP Portugal
Wed, Jul 15 - Fri, Jul 31
PDX
Portland
TMS
São Tomé Island
$4,007 Roundtrip, found 2 days ago
$4,007
Roundtrip
found 2 days ago
Select TAP Portugal flight, departing Wed, Jul 15 from Portland to São Tomé Island, returning Fri, Jul 31, priced at $4,007 found 2 days ago
TAP Portugal
Wed, Jul 15 - Fri, Jul 31
PDX
Portland
TMS
São Tomé Island
$4,017 Roundtrip, found 2 days ago
$4,017
Roundtrip
found 2 days ago
Select TAP Portugal flight, departing Wed, Jul 15 from Portland to São Tomé Island, returning Fri, Jul 31, priced at $4,017 found 2 days ago
TAP Portugal
Wed, Jul 15 - Fri, Jul 31
PDX
Portland
TMS
São Tomé Island
$4,029 Roundtrip, found 2 days ago
$4,029
Roundtrip
found 2 days ago
Select TAP Portugal flight, departing Wed, Jul 15 from Portland to São Tomé Island, returning Fri, Jul 31, priced at $4,029 found 2 days ago
TAP Portugal
Wed, Jul 15 - Fri, Jul 31
PDX
Portland
TMS
São Tomé Island
$4,075 Roundtrip, found 2 days ago
$4,075
Roundtrip
found 2 days ago
Select TAP Portugal flight, departing Wed, Jul 15 from Portland to São Tomé Island, returning Fri, Jul 31, priced at $4,075 found 2 days ago
TAP Portugal
Wed, Jul 15 - Fri, Jul 31
PDX
Portland
TMS
São Tomé Island
$4,126 Roundtrip, found 2 days ago
$4,126
Roundtrip
found 2 days ago
Select TAP Portugal flight, departing Wed, Jul 15 from Portland to São Tomé Island, returning Fri, Jul 31, priced at $4,126 found 2 days ago
TAP Portugal
Wed, Jul 15 - Fri, Jul 31
PDX
Portland
TMS
São Tomé Island
$4,173 Roundtrip, found 2 days ago
$4,173
Roundtrip
found 2 days ago
Select TAP Portugal flight, departing Wed, Jul 15 from Portland to São Tomé Island, returning Fri, Jul 31, priced at $4,173 found 2 days ago
TAP Portugal
Wed, Jul 15 - Fri, Jul 31
PDX
Portland
TMS
São Tomé Island
$4,223 Roundtrip, found 2 days ago
$4,223
Roundtrip
found 2 days ago
Select TAP Portugal flight, departing Wed, Jul 15 from Portland to São Tomé Island, returning Fri, Jul 31, priced at $4,223 found 2 days ago
TAP Portugal
Wed, Jul 15 - Fri, Jul 31
PDX
Portland
TMS
São Tomé Island
$4,271 Roundtrip, found 2 days ago
$4,271
Roundtrip
found 2 days ago
Select TAP Portugal flight, departing Wed, Jul 15 from Portland to São Tomé Island, returning Fri, Jul 31, priced at $4,271 found 2 days ago

Frequently asked questions

How much does a flight from Portland Intl. Airport (PDX) to Sao Tome Intl. Airport (TMS) cost?
Secure a cheap one-way flight from $2,196 or cheap return flight from $3,897 from Portland Intl. Airport (PDX) to Sao Tome Intl. Airport (TMS) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Portland Intl. Airport (PDX) to Sao Tome Intl. Airport (TMS)?
The cheapest month to fly from PDX to TMS is July, when demand is low. Off-peak months are typically when you'll find cheap fares for travel between these airports.
What is the cheapest airline that flies from Portland Intl. Airport (PDX) to Sao Tome Intl. Airport (TMS)?
To find the cheapest airline that'll fly you from PDX to TMS, use Expedia's filter tool. Tailor your search based on your travel needs, such as preferred carriers and cabin class. You can then sort your results by "Price (lowest to highest)" to list the most affordable options first.
How many flights per day from Portland Intl. Airport (PDX) to Sao Tome Intl. Airport (TMS)?
Nonstop flights from Portland Intl. Airport (PDX) to Sao Tome Intl. Airport (TMS) aren't available daily, so you'll need to take a flight with a layover. Explore your options with our filter tool. Enter your dates and pick either "1 Stop" or "2+ Stops."
What day of the week has the most flights from PDX to TMS?
Usually you'll find the largest variety of flight choices on a Friday. Tuesdays tend to be the quietest.* However, this can change based on the season, carrier and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Portland Intl. Airport (PDX) to Sao Tome Intl. Airport (TMS)?
To arrive at Sao Tome Intl. Airport (TMS) without delays, opt for a flight that leaves Portland Intl. Airport (PDX) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Portland Intl. Airport (PDX) to Sao Tome Intl. Airport (TMS) last-minute?
Holding off until just before your trip to book your flight from PDX to TMS often results in higher prices. Although you may find some last-minute deals, they aren't always guaranteed. Keep your travel schedule open to maximize your chances of snagging a bargain.
Is it cheaper to book a PDX to TMS flight and hotel package?
Opting for a PDX to TMS flight and hotel package tends to be cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your travels all in one place. Choose from our impressive range of hotels and then add car rentals, activities and flights to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Portland Intl. Airport (PDX) to Sao Tome Intl. Airport (TMS)?
In most instances, you can cancel or reschedule your PDX to TMS flight. However, there may be additional charges, especially if you booked over 24 hours ago. Check your itinerary for the airline's fees and rules on flight changes, or if you'd like more information, go to our Customer Service portal.

Travel information

Origin airport
Portland Intl.
Destination airport
São Tomé Intl.
Roundtrip price
$3,897
Distance
8015 mi

Book with confidence

Portland to São Tomé Island Flights

The cheapest times to fly from Portland to São Tomé Island

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Portland to São Tomé Island are during the month of July. You can find some of the cheapest flights from Portland to São Tomé Island with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Portland to São Tomé Island

Sunday is one of the best days to book for cheap flights from Portland to São Tomé Island: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Portland to São Tomé Island

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Portland to São Tomé Island in 2025. You can also book with separate airlines for your outbound and return journeys, from $2,196 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Portland to São Tomé Island flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Portland to São Tomé Island airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Portland to São Tomé Island Flights
*Available to One Key members.