$253 Cheap Flights from São Tomé Island (TMS) to Lisbon (LIS)

View $253 flight on Fri, Sep 26, 2025Opens in a new window

Popular airlines from São Tomé Island (TMS-São Tomé Intl.) to Humberto Delgado Airport (LIS)

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Cheap Flights from São Tomé Island to Lisbon (TMS-LIS)

Prices were available within the past 7 days and start at $253 for one-way flights and $418 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

TAAG Angola Airlines
Mon, Jan 19 - Sun, Feb 8
TMS
São Tomé Island
LIS
Lisbon
$418 Roundtrip, found 6 days ago
$418
Roundtrip
found 6 days ago
Select TAAG Angola Airlines flight, departing Mon, Jan 19 from São Tomé Island to Lisbon, returning Sun, Feb 8, priced at $418 found 6 days ago
TAAG Angola Airlines
Mon, Jan 12 - Sun, Feb 1
TMS
São Tomé Island
LIS
Lisbon
$453 Roundtrip, found 6 days ago
$453
Roundtrip
found 6 days ago
Select TAAG Angola Airlines flight, departing Mon, Jan 12 from São Tomé Island to Lisbon, returning Sun, Feb 1, priced at $453 found 6 days ago
TAAG Angola Airlines
Fri, Dec 26 - Thu, Jan 8
TMS
São Tomé Island
LIS
Lisbon
$489 Roundtrip, found 6 days ago
$489
Roundtrip
found 6 days ago
Select TAAG Angola Airlines flight, departing Fri, Dec 26 from São Tomé Island to Lisbon, returning Thu, Jan 8, priced at $489 found 6 days ago
TAAG Angola Airlines
Wed, Dec 31 - Sun, Jan 18
TMS
São Tomé Island
LIS
Lisbon
$494 Roundtrip, found 6 days ago
$494
Roundtrip
found 6 days ago
Select TAAG Angola Airlines flight, departing Wed, Dec 31 from São Tomé Island to Lisbon, returning Sun, Jan 18, priced at $494 found 6 days ago
TAAG Angola Airlines
Mon, Dec 15 - Tue, Dec 30
TMS
São Tomé Island
LIS
Lisbon
$518 Roundtrip, found 6 days ago
$518
Roundtrip
found 6 days ago
Select TAAG Angola Airlines flight, departing Mon, Dec 15 from São Tomé Island to Lisbon, returning Tue, Dec 30, priced at $518 found 6 days ago
TAAG Angola Airlines
Wed, Dec 31 - Sun, Jan 11
TMS
São Tomé Island
LIS
Lisbon
$530 Roundtrip, found 6 days ago
$530
Roundtrip
found 6 days ago
Select TAAG Angola Airlines flight, departing Wed, Dec 31 from São Tomé Island to Lisbon, returning Sun, Jan 11, priced at $530 found 6 days ago
TAAG Angola Airlines
Mon, Dec 15 - Sun, Dec 28
TMS
São Tomé Island
LIS
Lisbon
$554 Roundtrip, found 6 days ago
$554
Roundtrip
found 6 days ago
Select TAAG Angola Airlines flight, departing Mon, Dec 15 from São Tomé Island to Lisbon, returning Sun, Dec 28, priced at $554 found 6 days ago
TAAG Angola Airlines
Mon, Dec 29 - Sun, Jan 18
TMS
São Tomé Island
LIS
Lisbon
$555 Roundtrip, found 6 days ago
$555
Roundtrip
found 6 days ago
Select TAAG Angola Airlines flight, departing Mon, Dec 29 from São Tomé Island to Lisbon, returning Sun, Jan 18, priced at $555 found 6 days ago
TAP Portugal
Sun, Mar 29 - Wed, Apr 15
TMS
São Tomé Island
LIS
Lisbon
$569 Roundtrip, found 6 days ago
$569
Roundtrip
found 6 days ago
Select TAP Portugal flight, departing Sun, Mar 29 from São Tomé Island to Lisbon, returning Wed, Apr 15, priced at $569 found 6 days ago
TAAG Angola Airlines
Mon, Dec 22 - Thu, Jan 8
TMS
São Tomé Island
LIS
Lisbon
$591 Roundtrip, found 6 days ago
$591
Roundtrip
found 6 days ago
Select TAAG Angola Airlines flight, departing Mon, Dec 22 from São Tomé Island to Lisbon, returning Thu, Jan 8, priced at $591 found 6 days ago

Alternative airports near Lisbon

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Humberto Delgado LIS. Cheapest option available. Flights from $1,834
LIS
Humberto Delgado
Cheapest
Flights from $1,834
Flights from São Tomé Island (TMS) to Lisbon (LIS)
Origin airport
São Tomé Intl.
Destination airport
Humberto Delgado
Airlines serving
TAP Portugal
Roundtrip price
$417
Distance
2836 mi
Average flight time
8 hours 6 mins

São Tomé Island to Lisbon Flights

The cheapest times to fly from São Tomé Island to Lisbon

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from São Tomé Island to Lisbon are during the month of January. You can find some of the cheapest flights from São Tomé Island to Lisbon with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from São Tomé Island to Lisbon

Sunday is one of the best days to book for cheap flights from São Tomé Island to Lisbon: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from São Tomé Island to Lisbon

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from São Tomé Island to Lisbon in 2025. You can also book with separate airlines for your outbound and return journeys, from $253 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap São Tomé Island to Lisbon flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your São Tomé Island to Lisbon airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Sao Tome Intl. Airport (TMS) to Humberto Delgado Airport (LIS) cost?
Snag a cheap one-way flight from $253 or cheap return flight from $418 from Sao Tome Intl. Airport (TMS) to Humberto Delgado Airport (LIS) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Sao Tome Intl. Airport (TMS) to Humberto Delgado Airport (LIS)?
Traveling in January may help you find better deals, as it's the cheapest month for flights between TMS and LIS. You'll often find the lowest prices during the off-season.
Which airlines fly direct from Sao Tome Intl. Airport (TMS) to Humberto Delgado Airport (LIS)?
Catch a nonstop flight with STP Airways and fly straight from Sao Tome Intl. Airport (TMS) to Humberto Delgado Airport (LIS).
What is the cheapest airline that flies from Sao Tome Intl. Airport (TMS) to Humberto Delgado Airport (LIS)?
TAP Portugal and STP Airways are some popular carriers offering reasonable fares. Keep in mind that flight prices from Sao Tome Intl. Airport (TMS) to Humberto Delgado Airport (LIS) can change depending on the time of year, demand and how early you book. With Expedia's filter tool, you can easily find a TMS to LIS flight that matches your preferences and budget.
How many flights per day from Sao Tome Intl. Airport (TMS) to Humberto Delgado Airport (LIS)?
On average, you can pick from 2 direct flights every week from Sao Tome Intl. Airport (TMS) to Humberto Delgado Airport (LIS). For greater flexibility, consider taking a flight with a layover. Enter your details on Expedia and then filter your search to show one or two stops.
What are the most popular departure times for flights from Sao Tome Intl. Airport (TMS) to Humberto Delgado Airport (LIS)?
More passengers fly between TMS and LIS at 7 AM than at any other time. Looking for a quieter experience? Consider flying outside peak hours and there's a chance you'll save on your ticket as well.
What day of the week has the most flights from TMS to LIS?
Saturday has the most flights from Sao Tome Intl. Airport (TMS) to Humberto Delgado Airport (LIS). Consider leaving on this day and you'll have a greater chance of finding a departure that fits your itinerary.
What is the earliest flight from Sao Tome Intl. Airport (TMS) to Humberto Delgado Airport (LIS)?
Sao Tome Intl. Airport (TMS)'s first flight to Humberto Delgado Airport (LIS) takes off at approximately 7:50AM UTC+0. With a total travel time of 6h 15m, you'll touch down at around 2:05PM UTC+0.
How long does it take to fly from Sao Tome Intl. Airport (TMS) to Humberto Delgado Airport (LIS)?
Typically, it takes 6 hours and 27 minutes to fly the 2,800 mi from TMS to LIS.
What is the best time to fly from Sao Tome Intl. Airport (TMS) to Humberto Delgado Airport (LIS)?
To arrive at Humberto Delgado Airport (LIS) on schedule, choose a flight that takes off from Sao Tome Intl. Airport (TMS) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for Lisbon District from Sao Tome Intl. Airport (TMS)?
If you've booked a direct flight from Sao Tome Intl. Airport (TMS) to Lisbon District, Humberto Delgado Airport (LIS) is the only airport you can touch down at.
Is it cheaper to buy a plane ticket from Sao Tome Intl. Airport (TMS) to Humberto Delgado Airport (LIS) last-minute?
Booking your ticket from TMS to LIS just before your trip is generally more expensive. But if there's some wiggle room with your departure dates and times, you could land a cheap last-minute fare.
Is it cheaper to book a TMS to LIS flight and hotel package?
Compared with arranging flights and hotels separately, booking a TMS to LIS flight and hotel package with Expedia could lead to significant savings. Better still, having everything in one place takes the hassle out of planning your trip. Just secure your flights and choose from our wide range of hotels, then personalize your trip with extras like activities, tours and car rentals.
Can I cancel or change the date of my flight from Sao Tome Intl. Airport (TMS) to Humberto Delgado Airport (LIS)?
Typically, you're able to cancel or reschedule your TMS to LIS flight. However, there may be additional fees, especially if your booking was made more than 24 hours ago. Double-check your itinerary for the airline's rules and fees on flight changes, or if you need further details, head to our Customer Service portal.

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*Available to One Key members.