$296 Cheap Flights from Knoxville (TYS) to Cali (CLO)

View $296 flight on Wed, Nov 19, 2025Opens in a new window

Popular airlines from McGhee Tyson Airport (TYS) to Alfonso Bonilla Aragon Intl. Airport (CLO)

Cheap Flights from Knoxville to Cali (TYS-CLO)

Prices were available within the past 7 days and start at $296 for one-way flights and $522 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

United
Tue, Feb 3 - Wed, Feb 11
TYS
Knoxville
CLO
Cali
$522 Roundtrip, found 4 days ago
$522
Roundtrip
found 4 days ago
Select United flight, departing Tue, Feb 3 from Knoxville to Cali, returning Wed, Feb 11, priced at $522 found 4 days ago
United
Thu, Feb 5 - Fri, Feb 13
TYS
Knoxville
CLO
Cali
$531 Roundtrip, found 4 days ago
$531
Roundtrip
found 4 days ago
Select United flight, departing Thu, Feb 5 from Knoxville to Cali, returning Fri, Feb 13, priced at $531 found 4 days ago
United
Thu, Feb 5 - Mon, Feb 9
TYS
Knoxville
CLO
Cali
$546 Roundtrip, found 4 days ago
$546
Roundtrip
found 4 days ago
Select United flight, departing Thu, Feb 5 from Knoxville to Cali, returning Mon, Feb 9, priced at $546 found 4 days ago
United
Fri, Feb 6 - Fri, Feb 13
TYS
Knoxville
CLO
Cali
$553 Roundtrip, found 4 days ago
$553
Roundtrip
found 4 days ago
Select United flight, departing Fri, Feb 6 from Knoxville to Cali, returning Fri, Feb 13, priced at $553 found 4 days ago
United
Fri, Feb 6 - Tue, Feb 10
TYS
Knoxville
CLO
Cali
$556 Roundtrip, found 4 days ago
$556
Roundtrip
found 4 days ago
Select United flight, departing Fri, Feb 6 from Knoxville to Cali, returning Tue, Feb 10, priced at $556 found 4 days ago
United
Fri, Feb 6 - Tue, Feb 10
TYS
Knoxville
CLO
Cali
$557 Roundtrip, found 4 days ago
$557
Roundtrip
found 4 days ago
Select United flight, departing Fri, Feb 6 from Knoxville to Cali, returning Tue, Feb 10, priced at $557 found 4 days ago
United
Sat, Feb 7 - Fri, Feb 13
TYS
Knoxville
CLO
Cali
$566 Roundtrip, found 4 days ago
$566
Roundtrip
found 4 days ago
Select United flight, departing Sat, Feb 7 from Knoxville to Cali, returning Fri, Feb 13, priced at $566 found 4 days ago
Delta
Thu, Oct 23 - Wed, Oct 29
TYS
Knoxville
CLO
Cali
$600 Roundtrip, found 5 days ago
$600
Roundtrip
found 5 days ago
Select Delta flight, departing Thu, Oct 23 from Knoxville to Cali, returning Wed, Oct 29, priced at $600 found 5 days ago
American Airlines
Fri, Feb 6 - Tue, Feb 10
TYS
Knoxville
CLO
Cali
$632 Roundtrip, found 4 days ago
$632
Roundtrip
found 4 days ago
Select American Airlines flight, departing Fri, Feb 6 from Knoxville to Cali, returning Tue, Feb 10, priced at $632 found 4 days ago
LATAM Airlines Group
Fri, Oct 24 - Wed, Oct 29
TYS
Knoxville
CLO
Cali
$640 Roundtrip, found 5 days ago
$640
Roundtrip
found 5 days ago
Select LATAM Airlines Group flight, departing Fri, Oct 24 from Knoxville to Cali, returning Wed, Oct 29, priced at $640 found 5 days ago

Frequently asked questions

How much does a flight from McGhee Tyson Airport (TYS) to Alfonso Bonilla Aragon Intl. Airport (CLO) cost?
Lock in a cheap one-way flight from $296 or cheap return flight from $522 from McGhee Tyson Airport (TYS) to Alfonso Bonilla Aragon Intl. Airport (CLO) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from McGhee Tyson Airport (TYS) to Alfonso Bonilla Aragon Intl. Airport (CLO)?
The cheapest month to fly from TYS to CLO is February, when demand is low. Off-peak season is often when airlines offer lower prices between these airports.
What is the cheapest airline that flies from McGhee Tyson Airport (TYS) to Alfonso Bonilla Aragon Intl. Airport (CLO)?
Expedia's filter tool lets you easily compare different airlines, travel time and fares all in one place. Customize the search to your preferences, then sort by "Price (lowest to highest)" to find the carrier with the cheapest TYS to CLO flight.
How many flights per day from McGhee Tyson Airport (TYS) to Alfonso Bonilla Aragon Intl. Airport (CLO)?
Nonstop flights from McGhee Tyson Airport (TYS) to Alfonso Bonilla Aragon Intl. Airport (CLO) aren't available daily, so you'll need to take a flight with a layover. Explore your options with Expedia's filter tool. Enter your dates and choose either "1 Stop" or "2+ Stops."
What day of the week has the most flights from TYS to CLO?
Generally you'll find the greatest selection of flight options on a Friday. Tuesdays are often the quietest.* However, this can change based on the time of year, airline and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from McGhee Tyson Airport (TYS) to Alfonso Bonilla Aragon Intl. Airport (CLO)?
To touch down at Alfonso Bonilla Aragon Intl. Airport (CLO) without delays, book a flight that leaves from McGhee Tyson Airport (TYS) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from McGhee Tyson Airport (TYS) to Alfonso Bonilla Aragon Intl. Airport (CLO) last-minute?
Last-minute fares from TYS to CLO are generally more expensive. To secure the lowest rates, start looking for flights well in advance. That being said, if you're flexible with your travel dates, it's possible to land a cheap fare just before your departure.
Is it cheaper to book a TYS to CLO flight and hotel package?
Compared with arranging hotels and flights separately, booking a TYS to CLO flight and hotel package with Expedia could result in significant savings. Better yet, managing everything in one place will take the stress out of planning your trip. Simply pick your flights and select from our extensive range of hotels, then personalize your trip with extras like tours, activities and car rentals.
Can I cancel or change the date of my flight from McGhee Tyson Airport (TYS) to Alfonso Bonilla Aragon Intl. Airport (CLO)?
Usually, it's possible to reschedule or cancel your TYS to CLO flight. However, if the booking was made more than 24 hours ago, additional fees may apply. Check your airline's policies in your itinerary to see what changes are possible and if any costs are involved. You'll also find more information on our Customer Service portal.

Travel information

Travel information

Origin airport
McGhee Tyson
Destination airport
Alfonso Bonilla Aragon Intl.
Airlines serving
LATAM Airlines Group
Roundtrip price
$522
Distance
2281 mi

Book with confidence

Book with confidence

Knoxville to Cali Flights

The cheapest times to fly from Knoxville to Cali

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Knoxville to Cali are during the month of February. You can find some of the cheapest flights from Knoxville to Cali with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Knoxville to Cali

Sunday is one of the best days to book for cheap flights from Knoxville to Cali: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Knoxville to Cali

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Knoxville to Cali in 2025. You can also book with separate airlines for your outbound and return journeys, from $296 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Knoxville to Cali flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Knoxville to Cali airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Knoxville to Cali Flights

Explore a world of travel with Expedia

Explore a world of travel with Expedia

*Available to One Key members.