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Find hotels in Santiago Island from $45

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Compare 348 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Tiny house surrounded by a cedar forest!
10.0 out of 10, Exceptional, (1)
"Beautiful place with super accommodating host."
Tiny house surrounded by a cedar forest!
Hostal cielo azul
1.0 star property
10.0 out of 10, Exceptional, (1)
"I traveled from Florida to Galapagos Island wirh my family, but they have a issue and Quito aereopuerto, that cause to me traveled by myself, but Im arrived to Isabella Island alone , the owner pick up me from muelle, and help me with everything, phone calls to call my family, safety place, thank you so much. If a have to put 100 star's I do , becouse you are exelent person and exelent plece to stay thank you so much. Tomy .🇺🇸🙏"
Hostal cielo azul
Semilla Verde Boutique Hotel
3.5 star property
9.8 out of 10, Exceptional, (51)
"Katya the manager is an amazing person helpful and ,polite"
The price is $220
$242 total
includes taxes & fees
May 3 - May 4
Semilla Verde Boutique Hotel
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Espectacular Private Villa with Unbeatable Views
9.6 out of 10, Exceptional, (8)
"second time , we love Casa Roca - cant wait to return"
Espectacular Private Villa with Unbeatable Views
Piedras Blancas Lodge
2.5 star property
9.0 out of 10, Wonderful, (8)
"I like a lot the place! Very quiet and surrounded by nature. Rooms where perfectly clean and had a lot of space! We would like more options to eat, restaurant only opens for breakfast. Lunch and dinner has to be pre ordered. Beautiful place to relax"
Piedras Blancas Lodge
Suymar Ecolodge Galapagos
3.0 star property
8.6 out of 10, Excellent, (11)
"Incredible stay - would highly recommend this to anyone looking to stay a little out of the port area but not too far"
The price is $200
$200 total
includes taxes & fees
May 3 - May 4
Suymar Ecolodge Galapagos
Twin Hotel Galapagos
3.0 star property
8.4 out of 10, Very Good, (35)
"This is a horrible hotel. The WiFi doesn’t work even though they mentioned it would provide WiFi. The room and dining room were full of insects. The owner of the hotel is not a friendly person. When my boyfriend and I complained about the WiFi and the insects being everywhere, Maria Jose, the owner made a bunch of excuses. My boyfriend and I asked for a refund and Maria Jose overreacted and said that it was impossible to give a refund and she didn’t want to do it. My boyfriend and I got scammed....
The price is $67
$67 total
includes taxes & fees
May 3 - May 4
Twin Hotel Galapagos
Hotel Galapagos Tortuga Bay
2.0 star property
8.0 out of 10, Very Good, (4)
"Nono"
The price is $104
$114 total
includes taxes & fees
May 17 - May 18
Hotel Galapagos Tortuga Bay
Suite con 2 Habitaciones
Suite con 2 Habitaciones
Modern Private Galapagos Villa
Modern Private Galapagos Villa
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Stay near popular Santiago Island attractions

Frequently asked questions

If I need to cancel my hotel reservation in Santiago Island, will I receive a refund?

Yes! You'll find that most room reservations are refundable if you cancel before the hotel’s cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you may still be able to cancel and receive a refund within 24 hours of booking. Filter your search by free cancellation to find flexible hotel deals in Santiago Island.

Where can I learn more about changing or cancelling my trip to Santiago Island?

To find more details about updating your trip to Santiago Island or cancelling it, click here.

What is staying in Santiago Island like?

Visitors can enjoy all that Santiago Island has to offer including its parks. A top sight in the city is Galapagos National Park. Find out more about Santiago Island.

What are the top places to visit in Santiago Island?

The picturesque setting of Galapagos National Park and Mosquera Island exemplify the area's natural beauty. Additionally, you might want to add Puerto Egas to your itinerary. Check out what more to see and do in Expedia's Santiago Island guide.

What's the seasonal weather like in Santiago Island?

The hottest months are usually January and February with an average temp of 84°F, while the coldest months are August and September with an average of 74°F. Average annual precipitation for Santiago Island is 24 inches.

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