Find hotels in Upstate South Carolina, SC from $60

    Plan, book, stay with confidence
    bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    one key icon
    Treat yourself
    Save instantly and earn perks with One Key
    Learn about One Key
    today icon
    Change your mind
    Book hotels with free cancellation

Find properties with these dates

Tonight
May 3 - May 4
Tomorrow
May 4 - May 5
This weekend
May 3 - May 5

Filter by

Popular filters
Popular filters
Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Popular locations
Popular locations
Meal plans available
Meal plans available
Amenities
Amenities
Accessibility
Accessibility
Traveler experience
Traveler experience

Compare 2,550 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Grand Bohemian Lodge Greenville, Autograph Collection
Lobby
Grand Bohemian Lodge Greenville, Autograph Collection
4.0 star property
9.4 out of 10, Exceptional, (182)
"Loud music playing outside our room on a Tuesday night. "
The price is $332
$365 total
includes taxes & fees
May 27 - May 28
Grand Bohemian Lodge Greenville, Autograph Collection
Hyatt Regency Greenville
Property entrance
Hyatt Regency Greenville
3.5 star property
8.8 out of 10, Excellent, (1003)
"Hotel had a perfect location wonderful lobby and room was very clean. Only bad thing is our Bottom sheets on the bed were put on sideways on both beds, therefore your feet were touching the mattress cover and there was about 3 feet on each side that was hanging to the floor. Very strange we had to remake our beds. Next day made service missed us. Also ice machine was not working on the floor, other than that room was great for the price "
The price is $152
$172 total
includes taxes & fees
May 19 - May 20
Hyatt Regency Greenville
Cambria Hotel Greenville
Property amenity
Cambria Hotel Greenville
3.0 star property
9.4 out of 10, Exceptional, (641)
"Loved the hotel and the staff was so sweet! "
The price is $114
$125 total
includes taxes & fees
May 12 - May 13
Cambria Hotel Greenville
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free
Drury Inn & Suites Greenville
Indoor pool, outdoor pool
Drury Inn & Suites Greenville
3.0 star property
9.4 out of 10, Exceptional, (1001)
"Very clean, friendly, comfortable and hospitable place to stay."
The price is $117
$129 total
includes taxes & fees
May 12 - May 13
Drury Inn & Suites Greenville
Hyatt Place Greenville/Downtown
Exterior
Hyatt Place Greenville/Downtown
3.0 star property
9.0 out of 10, Wonderful, (1022)
"Our stay was very pleasant. The only issue was tgat we arrived at 1am. We paid for parking but there was no valet on duty. We were asked to park the car in the back of the building and they said they would take care of it. Although they asked us to hold onto tge keys. We were awoken at 7am as they needed the keys we offered to leave with them. "
The price is $161
$182 total
includes taxes & fees
May 12 - May 13
Hyatt Place Greenville/Downtown
Comfort Suites Greenville Airport
Individually decorated, individually furnished, desk, laptop workspace
Comfort Suites Greenville Airport
2.5 star property
9.4 out of 10, Exceptional, (731)
"Front desk staff was so nice. Room was clean and comfortable. Shower was AMAZING "
The price is $99
$108 total
includes taxes & fees
May 19 - May 20
Comfort Suites Greenville Airport
Comfort Suites At WestGate Mall
Seasonal outdoor pool
Comfort Suites At WestGate Mall
2.5 star property
8.2 out of 10, Very Good, (1003)
"Very clean and well run. A great value."
The price is $88
$98 total
includes taxes & fees
May 12 - May 13
Comfort Suites At WestGate Mall
Holiday Inn Express & Suites Greenville - Downtown, an IHG Hotel
Exterior
Holiday Inn Express & Suites Greenville - Downtown, an IHG Hotel
2.5 star property
8.6 out of 10, Excellent, (1004)
"The front desk girls are friendly and accommodating, good breakfast, clean room and bathroom, walking distance to downtown, we had a good experience "
The price is $135
$149 total
includes taxes & fees
May 29 - May 30
Holiday Inn Express & Suites Greenville - Downtown, an IHG Hotel
The Shepherd Hotel Downtown Clemson
Superior Room, 2 Queen Beds | In-room safe, blackout drapes, soundproofing, iron/ironing board
The Shepherd Hotel Downtown Clemson
4.0 star property
9.8 out of 10, Exceptional, (260)
"Amazing hotel located in the heart of downtown Clemson! We had a great stay! "
The price is $169
$188 total
includes taxes & fees
May 12 - May 13
The Shepherd Hotel Downtown Clemson
Best Western Greenville Airport Inn
Lobby
Best Western Greenville Airport Inn
2.5 star property
7.8 out of 10, Good, (1002)
"Always a great place to stay Affordable and has breakfast 7 days a week and very convenient The staff is always friendly and helpful and it's clean I always stay here when I'm in Greenville and hope they don't get completely booked when I need to stay in greenville"
The price is $70
$77 total
includes taxes & fees
May 10 - May 11
Best Western Greenville Airport Inn
Days Inn by Wyndham Clayton
Room, 2 Queen Beds, Accessible, Non Smoking | Blackout drapes, iron/ironing board, free cribs/infant beds
Days Inn by Wyndham Clayton
2.0 star property
6.8 out of 10, (683)
"Check-in was quick and easy. Nice gentleman at the front desk. My room was very clean and smelled nice. The bed was amazingly comfortable and I had a great night’s sleep. Reasonable rate. Quite pleased!"
The price is $69
$85 total
includes taxes & fees
May 20 - May 21
Days Inn by Wyndham Clayton
Comfort Suites Anderson-Clemson
Lobby
Comfort Suites Anderson-Clemson
2.5 star property
8.4 out of 10, Very Good, (878)
"Outstanding in being clean, and quite location for goodnight sleep. Area has lot of restaurant's in walking distance. "
The price is $89
$99 total
includes taxes & fees
May 19 - May 20
Comfort Suites Anderson-Clemson
Holiday Inn Express Brevard City Center, an IHG Hotel
Exterior
Holiday Inn Express Brevard City Center, an IHG Hotel
2.5 star property
9.2 out of 10, Wonderful, (360)
"Overall a very positive experience. Friendly staff. Good restaurants in walking distance. I turned the thermostat from 74 to 65 for sleeping, but it took about 8 minutes for the unit to respond. Staff said that often happens. Bathroom is basic and has large dispenses of body wash, shampoo, and conditioner. Small fridge. Plenty of storage space. about 30" flat screen that you can cast to."
The price is $114
$127 total
includes taxes & fees
May 5 - May 6
Holiday Inn Express Brevard City Center, an IHG Hotel
Holiday Inn Express & Suites Clemson, an IHG Hotel
Exterior
Holiday Inn Express & Suites Clemson, an IHG Hotel
2.5 star property
9.0 out of 10, Wonderful, (776)
"Very coneveniet"
The price is $119
$132 total
includes taxes & fees
May 5 - May 6
Holiday Inn Express & Suites Clemson, an IHG Hotel
Holiday Inn Express & Suites Greenville Airport, an IHG Hotel
Exterior
Holiday Inn Express & Suites Greenville Airport, an IHG Hotel
2.5 star property
8.0 out of 10, Very Good, (698)
"Everything was great"
The price is $112
$123 total
includes taxes & fees
May 26 - May 27
Holiday Inn Express & Suites Greenville Airport, an IHG Hotel
The Abernathy of Clemson
Flat-screen TV
The Abernathy of Clemson
4.0 star property
9.6 out of 10, Exceptional, (388)
"Great"
The price is $136
$152 total
includes taxes & fees
May 23 - May 24
The Abernathy of Clemson
Days Inn by Wyndham Seneca / Clemson Area
Lobby
Days Inn by Wyndham Seneca / Clemson Area
2.0 star property
7.0 out of 10, Good, (597)
"Excellent front desk service. Nice and clean room, small but had everything needed. Property kept in good condition. Fresh coffee always available. Safe area"
The price is $71
$78 total
includes taxes & fees
Jun 3 - Jun 4
Days Inn by Wyndham Seneca / Clemson Area
Quality Inn
Standard Room, 2 Queen Beds, Non Smoking | Pillowtop beds, desk, iron/ironing board, free cribs/infant beds
Quality Inn
2.0 star property
7.2 out of 10, Good, (705)
"Very nice & very clean "
The price is $60
$66 total
includes taxes & fees
May 19 - May 20
Quality Inn
Holiday Inn Express Hotel & Suites Anderson-I-85, an IHG Hotel
Lobby lounge
Holiday Inn Express Hotel & Suites Anderson-I-85, an IHG Hotel
2.5 star property
9.2 out of 10, Wonderful, (417)
"Enjoyed my trip there… Will be staying there again soon."
The price is $116
$129 total
includes taxes & fees
Jun 2 - Jun 3
Holiday Inn Express Hotel & Suites Anderson-I-85, an IHG Hotel
Best Western Plus Greenville South
Pillowtop beds, in-room safe, desk, laptop workspace
Best Western Plus Greenville South
2.5 star property
8.4 out of 10, Very Good, (496)
"Great Stay!"
The price is $89
$99 total
includes taxes & fees
May 12 - May 13
Best Western Plus Greenville South
Don't see what you're looking for?
See all available properties in Upstate South Carolina
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Upstate South Carolina

Find the best Upstate South Carolina areas and neighborhoods for the activities you enjoy most. Learn more about Upstate South Carolina
Greenville featuring autumn leaves, a garden and a bridge

Greenville Downtown

3 out of top 10 points of interest in this area
5/5(654 area reviews)

The ample dining options and beautiful river views are top of the list for many visitors to Greenville Downtown. A stop by The Peace Center or Bon Secours Wellness Arena might round out your trip.

Find hotels in Greenville Downtown

More cheap stays in Upstate South Carolina

Best Western Plus Greenville I-385 Inn & Suites

Best Western Plus Greenville I-385 Inn & Suites

831 Congaree Rd, Greenville, SC
The price is $85 per night from May 12 to May 13
$85
$93 total
includes taxes & fees
May 12 - May 13
9/10 Wonderful! (1,180 reviews)

Stay near popular Upstate South Carolina attractions

Image for Clemson University

Clemson University

5/5(410 reviews)

Enjoy the collegiate vibe when you visit Clemson University, during your travels in Clemson. Experience the area's theater scene or attend a football game.

See properties
Clemson University

Recent reviews of Upstate South Carolina hotels
Expedia verified reviews

Drury Inn & Suites Greenville

Drury Inn & Suites Greenville

5/5 Excellent
Satisfied ❤️
"Very clean, friendly, comfortable and hospitable place to stay."
A verified traveler stayed at Drury Inn & Suites Greenville
Posted 2 days ago
Drury Inn & Suites Greenville