Find hotels in Upstate South Carolina, SC from $60

    Plan, book, stay with confidence
    bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    one key icon
    Treat yourself
    Save instantly and earn perks with One Key
    today icon
    Change your mind
    Book hotels with free cancellation

Check Upstate South Carolina hotel prices

Tomorrow night
This weekend

Filter by

Popular filters
Popular filters
Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Popular locations
Popular locations
Meal plans available
Meal plans available
Amenities
Amenities
Accessibility
Accessibility
Traveler experience
Traveler experience

Compare 2,511 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Grand Bohemian Lodge Greenville, Autograph Collection
4.0 star property
9.4 out of 10, Exceptional, (192)
"This hotel did not disappoint! The decor, the food and the overall vibe was impressive. Do yourself favor and stay here when visiting Greenville."
The price is $242
$266 total
includes taxes & fees
Jul 1 - Jul 2
Grand Bohemian Lodge Greenville, Autograph Collection
Hyatt Regency Greenville
3.5 star property
8.8 out of 10, Excellent, (1001)
"Weekend visit with the family. Hotel is clean and comfortable. Great location right on Main Street with plenty of restaurants and shopping. "
The price is $152
$172 total
includes taxes & fees
Jul 1 - Jul 2
Hyatt Regency Greenville
Cambria Hotel Greenville
3.0 star property
9.4 out of 10, Exceptional, (654)
"."
The price is $135
$149 total
includes taxes & fees
Jun 9 - Jun 10
Cambria Hotel Greenville
Save an average of 15% on thousands of hotels when you're signed in
Drury Inn & Suites Greenville
3.0 star property
9.4 out of 10, Exceptional, (1002)
"This was our first time at the Drury Inn and we stayed just one night. Normally wouldn't have chosen the location but it was convenient as we dropped our son off at camp. We were very impressed and will look at staying at these hotels in the future."
The price is $108
$119 total
includes taxes & fees
Jun 9 - Jun 10
Drury Inn & Suites Greenville
Courtyard by Marriott Greenville Downtown
3.0 star property
9.4 out of 10, Exceptional, (846)
"Nice hotel, pre pay parking from Expedia- it’s $5 on here or $16/night if you don’t prepay. Very walkable to anything you’d want in downtown Greenville. We had an executive suite and the bed/pillows were the comfiest I’ve had staying in a hotel. Very nice room size! Just with they had free breakfast. "
The price is $139
$157 total
includes taxes & fees
Jun 2 - Jun 3
Courtyard by Marriott Greenville Downtown
Hyatt Place Greenville/Downtown
3.0 star property
9.0 out of 10, Wonderful, (1006)
"None "
The price is $144
$163 total
includes taxes & fees
Jun 9 - Jun 10
Hyatt Place Greenville/Downtown
Comfort Suites Greenville Airport
2.5 star property
9.4 out of 10, Exceptional, (759)
"I will stay at this location again without hesitation if we travel through the area again. Very reasonably priced for as nice as it is. "
The price is $107
$118 total
includes taxes & fees
Jun 30 - Jul 1
Comfort Suites Greenville Airport
Comfort Suites At WestGate Mall
2.5 star property
8.2 out of 10, Very Good, (1003)
"👍"
The price is $93
$103 total
includes taxes & fees
Jun 9 - Jun 10
Comfort Suites At WestGate Mall
Holiday Inn Express Hotel & Suites Greenville, an IHG Hotel
2.5 star property
9.0 out of 10, Wonderful, (784)
"Clean, friendly staff, updated"
The price is $108
$121 total
includes taxes & fees
Jul 1 - Jul 2
Holiday Inn Express Hotel & Suites Greenville, an IHG Hotel
Holiday Inn Express & Suites Greenville - Downtown, an IHG Hotel
2.5 star property
8.6 out of 10, Excellent, (1003)
"great staff. appears this property has been recently updated. walkable to all downtown shops and restaurants"
The price is $127
$140 total
includes taxes & fees
Jul 1 - Jul 2
Holiday Inn Express & Suites Greenville - Downtown, an IHG Hotel
The Shepherd Hotel Downtown Clemson
4.0 star property
9.8 out of 10, Exceptional, (279)
"Very personalized staff! Looking forward to the next visit. "
The price is $169
$188 total
includes taxes & fees
Jun 16 - Jun 17
The Shepherd Hotel Downtown Clemson
Microtel Inn & Suites by Wyndham Anderson/Clemson
2.0 star property
8.2 out of 10, Very Good, (1001)
"The manager and staff were wonderful."
The price is $80
$89 total
includes taxes & fees
Jul 1 - Jul 2
Microtel Inn & Suites by Wyndham Anderson/Clemson
Best Western Greenville Airport Inn
2.5 star property
7.8 out of 10, Good, (1001)
"Great place to spend night when flying out of GSP. Shuttle service convenient and free hot breakfast!!"
The price is $78
$86 total
includes taxes & fees
Jul 1 - Jul 2
Best Western Greenville Airport Inn
Days Inn by Wyndham Clayton
2.0 star property
6.8 out of 10, (693)
"Friendly helpful staff."
The price is $77
$94 total
includes taxes & fees
Jun 6 - Jun 7
Days Inn by Wyndham Clayton
Holiday Inn Express Brevard City Center, an IHG Hotel
2.5 star property
9.2 out of 10, Wonderful, (368)
"Perfect location"
The price is $120
$134 total
includes taxes & fees
Jun 9 - Jun 10
Holiday Inn Express Brevard City Center, an IHG Hotel
Holiday Inn Express & Suites Clemson, an IHG Hotel
2.5 star property
9.0 out of 10, Wonderful, (781)
"Clean, comfortable, convenient "
The price is $120
$133 total
includes taxes & fees
Jun 16 - Jun 17
Holiday Inn Express & Suites Clemson, an IHG Hotel
Holiday Inn Express & Suites Greenville Airport, an IHG Hotel
2.5 star property
8.0 out of 10, Very Good, (706)
"Excellent "
The price is $100
$110 total
includes taxes & fees
Jun 9 - Jun 10
Holiday Inn Express & Suites Greenville Airport, an IHG Hotel
The Abernathy of Clemson
4.0 star property
9.6 out of 10, Exceptional, (396)
"The front desk young lady that checked me in was super helpful and attentive. This makes a world of a difference. Would definitely come back!"
The price is $159
$176 total
includes taxes & fees
Jun 16 - Jun 17
The Abernathy of Clemson
Days Inn by Wyndham Seneca / Clemson Area
2.0 star property
7.0 out of 10, Good, (605)
"Excellent front desk service. Nice and clean room, small but had everything needed. Property kept in good condition. Fresh coffee always available. Safe area"
The price is $72
$79 total
includes taxes & fees
Jun 6 - Jun 7
Days Inn by Wyndham Seneca / Clemson Area
Quality Inn
2.0 star property
7.0 out of 10, Good, (710)
"Pretty clean Staff nice Bed was comfortable Price was excellent "
The price is $60
$66 total
includes taxes & fees
Jun 16 - Jun 17
Quality Inn
Don't see what you're looking for?
See all available properties in Upstate South Carolina
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Upstate South Carolina

Find the best Upstate South Carolina areas and neighborhoods for the activities you enjoy most. Learn more about Upstate South Carolina

Stay near popular Upstate South Carolina attractions

Recent reviews of Upstate South Carolina hotels
Expedia verified reviews