Cheap Flights from Des Moines (DSM) to La Crosse (LSE)

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Cheap Flights from Des Moines to La Crosse (DSM-LSE)

Prices were available within the past 7 days and start at for one-way flights and $470 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
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American Airlines
Flights from Des Moines (DSM) to La Crosse (LSE)
Origin airport
Des Moines Intl.
Destination airport
La Crosse Municipal
Airlines serving
American Airlines
Roundtrip price
$470
Distance
202 mi

Des Moines to La Crosse Flights

Whether you’re looking for a grand adventure or just want to get away for a last-minute break, flights from Des Moines to La Crosse offer the perfect respite. Not only does exploring La Crosse provide the chance to make some magical memories, dip into delectable dishes, and tour the local landmarks, but the cheap airfare means you won’t bust your budget. So no matter whether your ideal itinerary involves flying one way, non-stop, or round trip, you’re bound to find flights that match your schedule on Expedia, and at prices that won’t shock your wallet.

Bagging a cheap flight from Des Moines to La Crosse may mean more dollars to spend on for one-of-a-kind souvenirs when you arrive, but it doesn’t mean you have to skimp on your travel experience, as Expedia offers a sizzling selection of cheap airlines that’ll put you in your happy place on their planes, whether that’s getting lost in a hair-raising airport thriller, dreaming on the passing landscape over a glass of bubbly, or jotting down your vacation bucket list at 38,000 feet. There’s also bound to be plenty of opportunities to snap a few photos of the high life that will make your friends green with envy. After all, enjoying the journey is part of the fun.

With so many affordable flights and so many wonderful adventures awaiting you, there’s no reason to put off booking a fantastic flight from to today. So don’t leave it to the last minute to make your dream trip a reality: pack your bags with your go-to travel accessories, put together your list of must-see attractions and can’t-miss activities, and get ready to broaden your horizons – with Expedia, the wonders of La Crosse are only a plane trip away. Book your travel arrangements with us today!

If you would like to book flights to La Crosse more flexibly many prefer to purchase one-way tickets with options to take different airlines. A one way ticket to La Crosse is now!

Frequently asked questions

Is it cheaper to buy a plane ticket from Des Moines Intl. Airport to La Crosse Municipal Airport (LSE) last minute?
Booking your flight from Des Moines Intl. Airport to La Crosse Municipal Airport (LSE) last minute could save you some dough if you stumble on an amazing deal. However, airfares usually don’t get cheaper as the date of departure nears. If you wait, flights could also be booked up or the best seats taken (we hope you like the middle seat!). If you’d rather not hedge your bets, book well ahead of the date you want to leave. Keep in mind that some of the best deals can be found up to a year in advance. If your favorite carrier hasn’t released tickets yet, check back regularly as offers are constantly updated on Expedia.
What airports do you fly into for La Crosse from Des Moines?
Des Moines to La Crosse flights land at La Crosse Municipal Airport (LSE). Check in to your hotel and then head out and explore some of the city’s popular sights, such as University of Wisconsin-La Crosse and La Crosse Center. The airport is about 4 mi north of central La Crosse.
Can I change the date of my flight from Des Moines Intl. Airport (DSM) to La Crosse Municipal Airport (LSE)?
You can quickly make changes to your Des Moines Intl. Airport (DSM) to La Crosse Regional Airport trip via the Expedia Trips portal. But before amending dates or times, browse the rules and conditions in your itinerary to see what you’re able to do and if fees apply for changes. Some carriers charge a change fee per person, plus any difference in fare prices. But if you booked in the last 24 hours, you may be able to cancel for free and arrange new flights. You can also find your way to our Customer Service portal for more handy information and to connect with our Virtual Agent.
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