$74 Cheap Flights from New Orleans (MSY) to Knoxville (TYS)

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Flight deals we found

These prices are lower than our typical predictions for similar flights.
75% less than typical
$270
Roundtrip per traveler
Fri, Jul 26 - Mon, Jul 29
American AirlinesAmerican Airlines
4h 9m
4:12pm
9:21pm
MSY
1 stop • 54m in CLT
TYS
Found 6 hours ago
70% less than typical
$338
Roundtrip per traveler
Sat, May 4 - Tue, May 7
UnitedUnited
4h 49m
5:16pm
11:05pm
MSY
1 stop • 1h 2m in IAH
TYS
Found 23 hours ago
60% less than typical
$453
Roundtrip per traveler
Sat, May 4 - Sun, May 5
DeltaDelta
5h 28m
11:20am
5:48pm
MSY
1 stop • 1h 21m in DTW
TYS
Found 4 hours ago
60% less than typical
$481
Roundtrip per traveler
Sat, May 18 - Sun, May 19
American AirlinesAmerican Airlines
7h 10m
5:30am
1:40pm
MSY
1 stop • 3h 1m in DFW
TYS
Found 4 hours ago
60% less than typical
$265
Roundtrip per traveler
Sat, May 18 - Mon, May 20
American AirlinesAmerican Airlines
6h 13m
7:00am
2:13pm
MSY
1 stop • 3h 5m in CLT
TYS
Found 12 hours ago
60% less than typical
$248
Roundtrip per traveler
Sun, Jun 2 - Wed, Jun 5
DeltaDelta
3h 41m
5:30am
10:11am
MSY
1 stop • 1h 20m in ATL
TYS
Found 19 hours ago
55% less than typical
$308
Roundtrip per traveler
Fri, May 10 - Sun, May 12
UnitedUnited
4h 49m
5:16pm
11:05pm
MSY
1 stop • 1h 2m in IAH
TYS
Found 11 hours ago
60% less than typical
$270
Roundtrip per traveler
Fri, Jun 7 - Sat, Jun 15
American AirlinesAmerican Airlines
3h 40m
2:20pm
7:00pm
MSY
1 stop • 32m in CLT
TYS
Found 4 hours ago
60% less than typical
$235
Roundtrip per traveler
Wed, Jul 24 - Wed, Jul 31
American AirlinesAmerican Airlines
4h 37m
6:25pm
12:02am
+1
MSY
1 stop • 1h 21m in CLT
TYS
Found 21 hours ago
55% less than typical
$316
Roundtrip per traveler
Fri, May 10 - Sun, May 12
American AirlinesAmerican Airlines
5h 5m
6:13pm
12:18am
+1
MSY
1 stop • 1h 13m in DFW
TYS
Found 23 hours ago
50% less than typical
$315
Roundtrip per traveler
Mon, May 13 - Fri, May 17
American AirlinesAmerican Airlines
5h 36m
10:50am
5:26pm
MSY
1 stop • 2h 28m in CLT
TYS
Found 23 hours ago
50% less than typical
$316
Roundtrip per traveler
Fri, May 10 - Mon, May 13
American AirlinesAmerican Airlines
7h 10m
5:30am
1:40pm
MSY
1 stop • 3h 1m in DFW
TYS
Found 11 hours ago
50% less than typical
$333
Roundtrip per traveler
Mon, May 13 - Sat, May 18
UnitedUnited
4h 49m
5:16pm
11:05pm
MSY
1 stop • 1h 2m in IAH
TYS
Found 23 hours ago

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Cheap Flights from New Orleans to Knoxville (MSY-TYS)

Prices were available within the past 7 days and start at $74 for one-way flights and $157 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frontier Airlines
Frontier Airlines
Frontier Airlines
Frontier Airlines
Frontier Airlines
Frontier Airlines
Frontier Airlines
Frontier Airlines
Frontier Airlines
Frontier Airlines
Flights from New Orleans (MSY) to Knoxville (TYS)
Origin airport
Louis Armstrong New Orleans Intl.
Destination airport
McGhee Tyson
Airlines serving
American Airlines, Delta, Frontier Airlines, United
Roundtrip price
$157
Distance
541 mi

New Orleans to Knoxville Flights

Whether you’re looking for a grand adventure or just want to get away for a last-minute break, flights from New Orleans to Knoxville offer the perfect respite. Not only does exploring Knoxville provide the chance to make some magical memories, dip into delectable dishes, and tour the local landmarks, but the cheap airfare means you won’t bust your budget. So no matter whether your ideal itinerary involves flying one way, non-stop, or round trip, you’re bound to find flights that match your schedule on Expedia, and at prices that won’t shock your wallet.

Bagging a cheap flight from New Orleans to Knoxville may mean more dollars to spend on for one-of-a-kind souvenirs when you arrive, but it doesn’t mean you have to skimp on your travel experience, as Expedia offers a sizzling selection of cheap airlines that’ll put you in your happy place on their planes, whether that’s getting lost in a hair-raising airport thriller, dreaming on the passing landscape over a glass of bubbly, or jotting down your vacation bucket list at 38,000 feet. There’s also bound to be plenty of opportunities to snap a few photos of the high life that will make your friends green with envy. After all, enjoying the journey is part of the fun.

With so many affordable flights and so many wonderful adventures awaiting you, there’s no reason to put off booking a fantastic flight from to today. So don’t leave it to the last minute to make your dream trip a reality: pack your bags with your go-to travel accessories, put together your list of must-see attractions and can’t-miss activities, and get ready to broaden your horizons – with Expedia, the wonders of Knoxville are only a plane trip away. Book your travel arrangements with us today!

If you would like to book flights to Knoxville more flexibly many prefer to purchase one-way tickets with options to take different airlines. A one way ticket to Knoxville is $74 now!

Frequently asked questions

How much is a one-way flight from Louis Armstrong New Orleans Intl. Airport (MSY) to Knoxville Airport?
You can find one-way New Orleans flights to Knoxville starting from just $71. This data is based on the lowest fare found on Expedia for this journey leaving across the next three months and was last updated on May 1 2024 and has not changed since. This airfare is for an Frontier Airlines flight, leaving from Louis Armstrong New Orleans Intl. Airport (MSY) on May 9 2024 and touching down at Knoxville Airport.
Is it cheaper to buy a plane ticket from MSY to McGhee Tyson Airport (TYS) last minute?
Booking your trip from Louis Armstrong New Orleans Intl. Airport to Knoxville Airport last minute could save you money if you’re lucky enough to find a terrific deal. However, fares don’t usually get cheaper as the date of departure nears. If you take a wait-and-see approach, flights could also be booked out or the best seats taken (we hope you like the middle seat!). If you want to be on the safe side, book well ahead of when you want to leave. Remember that some of the most awesome deals can be found up to 12 months in advance. If your favorite airline hasn’t released its airfares yet, check back regularly as offers are updated on Expedia constantly.
What is the cheapest airline flying from Louis Armstrong New Orleans Intl. Airport (MSY) to McGhee Tyson Airport (TYS) in the next 90 days?
Based on airfares found on Expedia with a departure date within the next 90 days, Frontier Airlines is the cheapest airline flying from New Orleans to Knoxville. The fare between these destinations starts at $71. This flight jets off from Louis Armstrong New Orleans Intl. Airport on May 9 2024 and lands at Knoxville Airport. The price was last updated on May 1 2024 and has not changed since.
What's the cheapest price for a flight from Louis Armstrong New Orleans Intl. Airport (MSY) to McGhee Tyson Airport (TYS) next month?
With a one-way flight from New Orleans to Knoxville on offer for just $71, you’ll have extra cash to splash on fun adventures. This price was found after searching all available flights on Expedia within the next 30 days. This particular journey jets out from Louis Armstrong New Orleans Intl. Airport (MSY) on May 9 2024, lands at Knoxville Airport and is operated by Frontier Airlines. The price was last updated on May 1 2024 and has not changed since.
What airports do you fly into for Knoxville from New Orleans?
McGhee Tyson Airport (TYS), Gatlinburg, TN (GKT-Gatlinburg - Pigeon Forge) and Morristown, TN (MOR-Moore-Murrell) are your options when taking off from New Orleans to Knoxville. Approximately 12 mi south of the heart of Knoxville, McGhee Tyson Airport (TYS) is the city’s main hub. Take into account things like flight arrival and departure times and the distance to your hotel before settling on an airport. Ijams Nature Center and Knoxville Zoological Gardens are a couple of great attractions to put on your to-do list when you arrive at your destination.
Can I change the date of my flight from Louis Armstrong New Orleans Intl. Airport (MSY) to Knoxville Airport?
You can quickly and easily make changes to your Louis Armstrong New Orleans Intl. Airport to Knoxville Airport trip by logging in to the Expedia Trips portal. But before amending dates or times, review the conditions in your itinerary to see what you can do and if change fees apply. Some airlines charge a change fee per person, plus any difference in prices. But if you booked in the last 24 hours, you may be able to cancel for free and book new flights. You can also find your way to our Customer Service portal for further details and to chat with our Virtual Agent.
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