Featured airlines
- Be in the knowGet alerts if flight prices drop or rise*
- Book smarterSave up to 30% on select hotels after you book a flight*
Cheap Flights from Louisville to Knoxville (SDF-TYS)
Prices were available within the past 7 days and start at $123 for one-way flights and $245 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.
Origin airport | Louisville Intl. |
Destination airport | McGhee Tyson |
Airlines serving | American Airlines, Delta, United |
Roundtrip price | $245 |
Distance | 190 mi |
Louisville to Knoxville Flights
Whether you’re looking for a grand adventure or just want to get away for a last-minute break, flights from Louisville to Knoxville offer the perfect respite. Not only does exploring Knoxville provide the chance to make some magical memories, dip into delectable dishes, and tour the local landmarks, but the cheap airfare means you won’t bust your budget. So no matter whether your ideal itinerary involves flying one way, non-stop, or round trip, you’re bound to find flights that match your schedule on Expedia, and at prices that won’t shock your wallet.
Bagging a cheap flight from Louisville to Knoxville may mean more dollars to spend on for one-of-a-kind souvenirs when you arrive, but it doesn’t mean you have to skimp on your travel experience, as Expedia offers a sizzling selection of cheap airlines that’ll put you in your happy place on their planes, whether that’s getting lost in a hair-raising airport thriller, dreaming on the passing landscape over a glass of bubbly, or jotting down your vacation bucket list at 38,000 feet. There’s also bound to be plenty of opportunities to snap a few photos of the high life that will make your friends green with envy. After all, enjoying the journey is part of the fun.
With so many affordable flights and so many wonderful adventures awaiting you, there’s no reason to put off booking a fantastic flight from to today. So don’t leave it to the last minute to make your dream trip a reality: pack your bags with your go-to travel accessories, put together your list of must-see attractions and can’t-miss activities, and get ready to broaden your horizons – with Expedia, the wonders of Knoxville are only a plane trip away. Book your travel arrangements with us today!
If you would like to book flights to Knoxville more flexibly many prefer to purchase one-way tickets with options to take different airlines. A one way ticket to Knoxville is $123 now!
Frequently asked questions
- Trending Routes
- Trending Flights
- Top Flights Destinations
- More Popular Airlines
- Flights From Other Airports
- Expedia's Latest Trends
Top Routes from Louisville
- Louisville to Newark (SDF - EWR)
- Louisville to San Diego (SDF - SAN)
- Louisville to Los Angeles (SDF - LAX)
- Louisville to Miami (SDF - MIA)
- Louisville to Punta Cana (SDF - PUJ)
- Louisville to Tampa (SDF - TPA)
- Louisville to Fort Lauderdale (SDF - FLL)
- Louisville to New York (SDF - LGA)
- Louisville to Boston (SDF - BOS)
- Louisville to Denver (SDF - DEN)
- Louisville to Dallas (SDF - DAL)
- Louisville to Seattle (SDF - SEA)
Top Routes to Knoxville
- Chicago to Knoxville (ORD - TYS)
- Newark to Knoxville (EWR - TYS)
- Phoenix to Knoxville (PHX - TYS)
- San Diego to Knoxville (SAN - TYS)
- Los Angeles to Knoxville (LAX - TYS)
- Tampa to Knoxville (TPA - TYS)
- Detroit to Knoxville (DTW - TYS)
- Boston to Knoxville (BOS - TYS)
- New York to Knoxville (LGA - TYS)
- Salt Lake City to Knoxville (SLC - TYS)
- Denver to Knoxville (DEN - TYS)
- Sacramento to Knoxville (SMF - TYS)
Top Routes from Louisville
- United Louisville to Newark
- Alaska Airlines Louisville to San Diego
- American Airlines Louisville to Miami
- American Airlines Louisville to Punta Cana
- Delta Louisville to Tampa
- American Airlines Louisville to New York
- United Louisville to Denver
- Delta Louisville to Dallas
- Alaska Airlines Louisville to Seattle
Top Routes to Knoxville
- United Chicago to Knoxville
- United Newark to Knoxville
- Delta Los Angeles to Knoxville
- Delta Tampa to Knoxville
- American Airlines Detroit to Knoxville
- United Boston to Knoxville
- Delta New York to Knoxville
- Frontier Airlines Denver to Knoxville
- United Sacramento to Knoxville
- Alaska Airlines Seattle to Knoxville
Top Flight Destinations
- Flights to Las Vegas
- Flights to New York
- Flights to Orlando
- Flights to Panama City Beach
- Flights to Chicago
- Flights to San Diego
- Flights to Myrtle Beach
- Flights to Los Angeles
- Flights to Miami
- Flights to Destin
- Flights to Nashville
- Flights to Boston
- Flights to Key West
- Flights to Honolulu
- Flights to San Francisco
- Flights to New Orleans
- Flights to Houston
- Flights to Fort Lauderdale
- Flights to Atlanta
- Flights to Seattle
Nearby Airports
- Bowman Field Airport (LOU)
- Blue Grass Airport (LEX)
- Owensboro-Daviess County Regional Airport (OWB)
- Cincinnati - Northern Kentucky Intl. Airport (CVG)
- Cincinnati Municipal - Lunken Field Airport (LUK)
- Evansville Regional Airport (EVV)
- Butler County Regional Airport (HAO)
- Indianapolis Intl. Airport (IND)
- Delaware County Airport (MIE)
- James M. Cox Dayton Intl. Airport (DAY)