Title: The Best 5 Star Hotels in Wayne, NE  | Expedia.com

[Wayne Travel Guide](https://expedia.com/Wayne.dx10311)[Hotels in Wayne](https://expedia.com/Wayne-Hotels.d10311.Travel-Guide-Hotels)[Vacation Rentals in Wayne](https://expedia.com/Wayne-Vacation-Rentals.d10311.Travel-Guide-VacationRentals)[Flights to Wayne](https://expedia.com/Cheap-Flights-To-Wayne.d10311.Travel-Guide-Flights)[Car Rentals in Wayne](https://expedia.com/Car-Rentals-In-Wayne.d10311.Car-Rental-Guide)[Wayne Vacation Packages](https://expedia.com/Wayne.d10311.Destination-Travel-Guides)

![First Presbyterian Church](https://images.trvl-media.com/place/10311/c1d3cbd7-a6f7-4ea8-9ea2-7f3de39083f5.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

![](https://images.trvl-media.com/place/10311/c1d3cbd7-a6f7-4ea8-9ea2-7f3de39083f5.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check availability on Wayne 5 Star Hotels

Tonight

[Feb 9 - Feb 10](https://www.expedia.com/Hotel-Search?regionId=10311&startDate=2026-02-09&endDate=2026-02-10&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Feb 10 - Feb 11](https://www.expedia.com/Hotel-Search?regionId=10311&startDate=2026-02-10&endDate=2026-02-11&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Feb 13 - Feb 15](https://www.expedia.com/Hotel-Search?regionId=10311&startDate=2026-02-13&endDate=2026-02-15&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Feb 20 - Feb 22](https://www.expedia.com/Hotel-Search?regionId=10311&startDate=2026-02-20&endDate=2026-02-22&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

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## Learn more about Wayne

Nestled around the historic Wayne County Courthouse, this charming college town invites visitors to explore local heritage at the Wayne County Museum. Take time to wander the Wayne State College campus or let your four-legged friends run free at Wayne Bark Park.

[See all hotels in Wayne](https://www.expedia.com/Hotel-Search?startDate=2026-02-24&endDate=2026-02-25&adults=2&regionId=10311)

![First Presbyterian Church](https://images.trvl-media.com/place/10311/c1d3cbd7-a6f7-4ea8-9ea2-7f3de39083f5.jpg?impolicy=fcrop&w=900&h=600&p=1&q=high)

## Top Wayne Hotel Reviews

## Find out more about Wayne

Indulge yourself on your next getaway. After all, you love the finer things in life, both at home and when you book a getaway. You'll join the multitudes of vacationers who have made Wayne so popular in the last year. There's no reason to delay a getaway to Wayne any longer. Besides, the hotels in Wayne offer great customer service, averaging 4.0 in our ranking system, so you know you're in good hands. Our 5-star hotels in Wayne are the perfect places to relax in during your next getaway. Don't wait any longer!

### 5-Star Hotels in Wayne

You can expect high quality from your hotel. Spa treatments, delicious meals, and one-on-one attention are all waiting for you. You're sure to find exactly the accommodation you need. You'll be pleased to note that the hotels in Wayne offer great customer service, averaging 3.8 in our ranking system, so you know you're in good hands. What kind of amenities will make your stay a wonderful one? A Swedish massage to help your cares fall away? A concierge to help you make reservations at that outstanding restaurant? High thread-count sheets, delectable chocolate desserts, and even space for your family pet in some cases...these hotels have it all. Want to see for yourself? Plenty of visitors recommend this location. 

You won't sleep and order room service the entire time, though. We've got you covered. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. Whatever you plan to do, the 5-star hotels in Wayne are waiting for you to relax after an exciting day.

### Make Your Escape

The results are in, and Wayne 5-star hotels are the place to be when you book your next vacation. Additionally, these accommodations are highly rated -- 90% of visitors recommended 5-star hotels in Wayne! Expedia can help you land a great deal on accommodation. It's time to indulge yourself. Choose one of our Wayne 5-star hotels today and soothe yourself in complete comfort tomorrow.

## Frequently asked questions

### How much does it cost to stay in a 5-star hotel in Wayne?

> - Search for the lowest price per night

### What makes a hotel 5 stars in Wayne?

### Are there any 5-star all-inclusive resorts in Wayne?

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- [Hotels near Wayne County Courthouse ](https://www.expedia.com/Wayne-County-Courthouse-Hotels.0-l6300994-0.Travel-Guide-Filter-Hotels)
- [Hotels near Wayne State College ](https://www.expedia.com/Wayne-State-College-Hotels.0-l6300999-0.Travel-Guide-Filter-Hotels)
- [Winside Hotels ](https://www.expedia.com/Winside-Hotels.d3000349815.Travel-Guide-Hotels)
- [Emerson Hotels ](https://www.expedia.com/Emerson-Hotels.d553248634983302101.Travel-Guide-Hotels)
- [Pilger Hotels ](https://www.expedia.com/Pilger-Hotels.d3000349790.Travel-Guide-Hotels)
- [Wisner Hotels ](https://www.expedia.com/Wisner-Hotels.d553248634983441980.Travel-Guide-Hotels)
- [Pender Hotels ](https://www.expedia.com/Pender-Hotels.d3000446311.Travel-Guide-Hotels)
- [Motels in Pender ](https://www.expedia.com/Pender-Motels.d3000446311-aaMotels.Travel-Guide-Accommodation)
- [Randolph Hotels ](https://www.expedia.com/Randolph-Hotels.d553248634983586917.Travel-Guide-Hotels)
- [Coleridge Hotels ](https://www.expedia.com/Coleridge-Hotels.d3000349751.Travel-Guide-Hotels)
- [Waterbury Hotels ](https://www.expedia.com/Waterbury-Hotels.d553248634983429780.Travel-Guide-Hotels)
- [Martinsburg Hotels ](https://www.expedia.com/Martinsburg-Hotels.d553248634983363576.Travel-Guide-Hotels)
- [Stanton Hotels ](https://www.expedia.com/Stanton-Hotels.d553248634983553106.Travel-Guide-Hotels)
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- [Beemer Hotels ](https://www.expedia.com/Beemer-Hotels.d3000445925.Travel-Guide-Hotels)
- [3 Star Hotels in Hadar ](https://www.expedia.com/3Star-Hadar-Hotels.s30-0-d3000349762.Travel-Guide-Filter-Hotels)
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- [Pierce Hotels ](https://www.expedia.com/Pierce-Hotels.d3000446310.Travel-Guide-Hotels)

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- [Flights to Pierce ](https://www.expedia.com/Cheap-Flights-To-Pierce.d3000446310.Travel-Guide-Flights)

- [Visit Winside ](https://www.expedia.com/Winside.dx3000349815)
- [Visit Pilger ](https://www.expedia.com/Pilger.dx3000349790)
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- [Norfolk Arts Center ](https://www.expedia.com/Norfolk-Arts-Center-Norfolk.d553248621561875996.Vacation-Attraction)
- [Visit Norfolk ](https://www.expedia.com/Norfolk.dx2644)
- [Norfolk Vacations ](https://www.expedia.com/Norfolk.d2644.Destination-Travel-Guides)

- [Car rentals near Wayne County Museum ](https://www.expedia.com/Car-Rentals-In-Wayne-County-Museum.d6301010.Car-Rental-Guide)
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