Important: This destination may have COVID-19 travel restrictions in place, including specific restrictions for lodging. Check any national, local, and health advisories for this destination before you book.

Browse for St. Louis Resorts & Hotels with Spas from $75

Search over 1 million properties and 550 airlines worldwide

Members save 10% more on select hotels, cars, activities and vacation rentals. Sign up.

Free cancellation on most hotels. Because flexibility matters.

Top St. Louis Resorts & Hotels with Spas

Drury Plaza Hotel St. Louis Chesterfield
3 out of 5
355 Chesterfield Ctr, Chesterfield, MO
Free CancellationReserve now, pay when you stay
The price is $100 per night
4.7/5Exceptional! (986 reviews)

"Very clean and nice place, would recommend to all people to get a room here"…"

Reviewed on Jun 30, 2020

Drury Plaza Hotel St. Louis Chesterfield
Four Seasons Hotel St Louis
Great for spa weekends
5 out of 5
999 North Second Street, St. Louis, MO
Free CancellationReserve now, pay when you stay
The price is $336 per night
4.7/5Exceptional! (605 reviews)
Travelers like: full-service spa, sauna, steam room, massage
Travelers say...

"The day of my arrival began badly and kept getting worse, so when I arrived, at the hotel, at 6:30PM and was told my room was not ready, I was not pleased. I had to wait perhaps 15 minutes, but that was 15 minutes too long and I vowed to write not a negative or positive review. Getting to my room, ..."…"

Reviewed on Mar 15, 2020

Four Seasons Hotel St Louis
Drury Inn & Suites Southwest St. Louis
3 out of 5
5 Lambert Drury Place (I-44 & 141), Valley Park, MO
Free CancellationReserve now, pay when you stay
The price is $95 per night
4.6/5Exceptional! (989 reviews)

"Everything was to expectation. The beds were comfortable and the rooms were quiet. Even with Covid19 there was still a packaged breakfast."…"

Reviewed on Jul 1, 2020

Drury Inn & Suites Southwest St. Louis
Drury Plaza Hotel St. Louis at the Arch
3 out of 5
2 South 4th Street, St. Louis, MO
Free CancellationReserve now, pay when you stay
The price is $110 per night
4.6/5Exceptional! (4,207 reviews)

"Great location, right next door to the Gateway Arch. Staff was super friendly. Room was nice. The only thing I didn’t like was the layout of the hotel. Confusing, and almost impossible to find the right level of the parking garage."…"

Reviewed on Jul 1, 2020

Drury Plaza Hotel St. Louis at the Arch
The Ritz-Carlton, St. Louis
Great for spa weekends
4.5 out of 5
100 Carondelet Plaza, St. Louis, MO
Free CancellationReserve now, pay when you stay
The price is $309 per night
4.6/5Exceptional! (428 reviews)
Travelers like: spa services onsite, sauna, massage, facials
Travelers say...

"I like the staff and the pictures in the bedroom. The balcony showed the awesome arch view , with other sky scrapers around it. Bed and pillows was a great feel and shower was huge and comfy"…"

Reviewed on Jun 2, 2020

The Ritz-Carlton, St. Louis
Drury Inn & Suites St. Louis Convention Center
3 out of 5
711 N Broadway, St. Louis, MO
Free CancellationReserve now, pay when you stay
The price is $100 per night
4.4/5Wonderful! (990 reviews)

"We had a great stay, staff was awesome, facilities where clean, and the room comfortable. Close to everything,will stay again on our next trip to STL!"…"

Reviewed on Jun 19, 2020

Drury Inn & Suites St. Louis Convention Center
The Chase Park Plaza Royal Sonesta St. Louis
Great for spa weekends
4.5 out of 5
212 N Kingshighway, St. Louis, MO
Free CancellationReserve now, pay when you stay
The price is $129 per night
4.4/5Excellent! (2,078 reviews)
Travelers like: spa services onsite, massage
Travelers say...

"Excellent as always. Superb customer service and nice facility."…"

Reviewed on Jun 29, 2020

The Chase Park Plaza Royal Sonesta St. Louis
The Westin St. Louis
4.5 out of 5
811 Spruce St, St. Louis, MO
Free CancellationReserve now, pay when you stay
The price is $93 per night
4.4/5Excellent! (992 reviews)

"I like the shower and tub in the premium king room big comfy bed will return"…"

Reviewed on Jun 25, 2020

The Westin St. Louis
The Wildwood Hotel
3.5 out of 5
2801 Fountain Pl, Wildwood, MO
Free CancellationReserve now, pay when you stay
The price is $88 per night
4.4/5Excellent! (1,000 reviews)
Cozy, clean, comfortable........rushed!

"The bed was by far the most comfortable for a hotel bed, room was clean and cozy. Because of this Covid-19 pool was closed but was not informed of this prior to check in, nor the $50 hold for incidentals. When I was taking some of my things to the car, walking past the front desk, the clerk kind ..."…"

Reviewed on Mar 25, 2020

The Wildwood Hotel
DoubleTree by Hilton Hotel St. Louis - Chesterfield
Great for spa weekends
3.5 out of 5
16625 Swingley Ridge Rd, Chesterfield, MO
Free CancellationReserve now, pay when you stay
The price is $89 per night
4.3/5Excellent! (895 reviews)
Travelers like: spa services onsite, hot tub
Travelers say...

"Pools, basketball court, tennis courts, and workout facility are top notch."…"

Reviewed on Jun 21, 2020

DoubleTree by Hilton Hotel St. Louis - Chesterfield
Ameristar Casino Resort and Spa (St. Charles)
Great for spa weekends
4.5 out of 5
1 Ameristar Blvd, St. Charles, MO
Free CancellationReserve now, pay when you stay
The price is $159 per night
4.3/5Excellent! (991 reviews)
Travelers like: full-service spa, massage, facials, manicures and pedicures
Travelers say...

"Great"…"

Reviewed on Mar 16, 2020

Ameristar Casino Resort and Spa (St. Charles)
Homewood Suites by Hilton St Louis - Galleria
3 out of 5
8040 Clayton Road, Richmond Heights, MO
Free CancellationReserve now, pay when you stay
The price is $93 per night
4.3/5Excellent! (751 reviews)

"Great stay! Room was very clean staff exceeded all expectations."…"

Reviewed on Jun 8, 2020

Homewood Suites by Hilton St Louis - Galleria
Pear Tree Inn St. Louis Near Union Station
3 out of 5
2211 Market Street, St. Louis, MO
Free CancellationReserve now, pay when you stay
The price is $115 per night
4.3/5Excellent! (1,620 reviews)

"I was concerned that there was an odor of tobacco when getting off the elevator on the 6th floor. Fortunately, there was no smell of smoke in our room. I found the mattress to be too firm for my taste, but that is personal preference. Due to Covid19 the breakfast was very limited, but I do wish there ..."…"

Reviewed on Mar 26, 2020

Pear Tree Inn St. Louis Near Union Station
Hilton Garden Inn St. Louis Airport
3 out of 5
4450 Evans Place, St. Louis, MO
Free CancellationReserve now, pay when you stay
The price is $84 per night
4.1/5Very Good! (995 reviews)

"The staff was very professional and courteous. Friendly and easy going"…"

Reviewed on Jun 10, 2020

Hilton Garden Inn St. Louis Airport
Best Western Plus St. Louis West - Chesterfield
3 out of 5
32 Research Park Circle, St. Charles, MO
Free CancellationReserve now, pay when you stay
The price is $75 per night
4.1/5Very Good! (995 reviews)

"The hotel was under construction they’re doing renovations so needless to say things were less than desirable but still a good place to stay over all staff very helpful and friendly"…"

Reviewed on Jun 6, 2020

Best Western Plus St. Louis West - Chesterfield
Hilton St. Louis at the Ballpark
Great for spa weekends
4 out of 5
1 S Broadway, St. Louis, MO
Free CancellationReserve now, pay when you stay
The price is $93 per night
4.1/5Very Good! (1,083 reviews)
Travelers like: sauna, hot tub
Travelers say...

"Everything was perfect. Perfect location, the pool and hot tub were amazing! Definitely recommend this property"…"

Reviewed on Jun 23, 2020

Hilton St. Louis at the Ballpark
Hilton St. Louis Downtown at the Arch
4 out of 5
400 Olive St, St. Louis, MO
Free CancellationReserve now, pay when you stay
The price is $95 per night
4/5Very Good! (991 reviews)

"The room wasn’t very clean the floors could’ve been vacuumed better, I found a toenail in the window. No microwave in room when I went downstairs to use the microwave in the lobby it was disgusting. But the location of this hotel is great private parking was wonderful"…"

Reviewed on Jun 25, 2020

Hilton St. Louis Downtown at the Arch
Holiday Inn St Louis SW - Route 66
3 out of 5
10709 Watson Rd, St. Louis, MO
Free Cancellation
The price is $95 per night
3.8/5Good! (956 reviews)
Road trip home

"Stayed here on a road trip home from FL to MN. Girl at front desk very friendly. Disappointing there was no breakfast because of the COVID-19 precautions, but not hotels fault. Nice room and stay."…"

Reviewed on Mar 27, 2020

Holiday Inn St Louis SW - Route 66
Don't see what you're looking for?
We've got more Resorts & Hotels with Spas. Find the right one for you.
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

St. Louis Resorts & Spa Travel Guide

Indulge Yourself with a St. Louis Spa Vacation

Pack up your bag and forget your concerns to jumpstart your stress-free vacation. Seeking an extravagant spa hotel that nestles you in the lap of luxury? We got you covered. Would you prefer to rest in a soothing secluded spa hotel? No problem. In fact, this area is so popular that it saw a large increase of travelers that are making it their ultimate spot to unwind. Looking for a spa hotel to relax throughout the day, and which also has huge amount of options for a lively night out? Fortunately for you, St. Louis

Book a St. Louis Spa Vacation that Won't Break the Bank

There is no need to worry about securing a great hotel. St. Louis has tons of options to appease most any preference or budget. Decompress and stretch out for a bit. After that you can make your first appointment to indulge yourself at a nearby spa. After you've indulged yourself by enjoying a therapeutic massage, decompressing in the sauna, or taking it easy by the pool, you can spend the night checking out all The Gateway to the Westhas to offer. You may find it easier to relax knowing that you have chosen a spot that little tourist know about. After having such an easy-going night, you might be reluctant to tell others about your latest secret vacation destination. With so many eateries, bars, night clubs, and other entertaining options, you'll discover why this area is an an attraction for both locals and travelers that are looking for some excitement when the sun sets. Wherever you end up, just make sure to hang loose. Your spa weekend shouldn't be anything but super relaxing.

Providing plenty of quiet retreats and and serene surroundings, it's clear why an increasing number of people are choosing The Gateway to the Westas their stress-free spa holiday sanctuary.

When to Visit

St. Louis has distinct seasons, so you can expect hot temperatures in the summer with the average temperature in July reaching 80 degrees. Winters are chilly with average temperatures in January just below the freezing mark. If you enjoy winter sports, you can find a St. Louis ski resort that offers great slopes for skiing, snowboarding, and tubing. If you want to visit St. Louis when the weather is most pleasant and there are lots of festivals and other fun events going on, April and May are ideal. This is the perfect time to see the amazing variety of blooming flowers at the Missouri Botanical Garden. You can also enjoy pleasant temperatures and some exciting events, such as the Big Muddy Blues Festival and the Great Forest Park Balloon Race in early fall.

What to Do When You’re in St. Louis

There are many exciting things to see in the St. Louis area. The Gateway Arch rises majestically above downtown and attracts millions of visitors every year. You can either admire it from the ground or take a tram up to the top where you will have a great view of the city. Another destination that the whole family will enjoy is the City Museum, a unique museum that specializes in architectural pieces and re-purposed industrial objects. St. Louis also boats one of the largest zoos in the United States, with free admission. The St. Louis Zoo, which is located in Forest Park, has more than 18,000 animals, a Discovery Corner with a fantastic children’s zoo, and a very popular, climate-controlled section that houses penguins and puffins. You will also have no shortage of places to dine when you’re in St. Louis. This city is well known for its steakhouses and traditional American cuisine.

Amenities at St. Louis Resorts

There are many types of resorts in St. Louis whether you are looking for something cheap or you prefer the luxury of a 5-star resort. One option worth considering is an all-inclusive resort where your meals and amenities, including spa sessions, are included for one price. If you prefer to be outside of the city itself, you can search for resorts near St. Louis. Some nearby attractions include the St. Francois Mountains of the Ozarks, which is a scenic area where you can either stay or enjoy a day trip from St. Louis. Expedia.com can help you locate the perfect hotel or resort that will provide you with everything you need for your St. Louis trip.

Geography of St. Louis

St. Louis has long been a port city, due to its location on the western bank of the Mississippi River. A smaller river, the Meramec River, is on the southern boundary of the city. Across the Mississippi is Cahokia, Illinois, home of one of the largest archaeological sites in North America. You can get excellent views of the site, as well as the St. Louis skyline, from the top of Monk's Mound, the tallest pyramid north of Mesoamerica.

There are many reasons to visit St. Louis, whether you want to ride on a riverboat on the Mississippi, check out some art museums, or watch the St. Louis Cardinals play at Busch Stadium. Visit Expedia.com today to find cheap flights to St. Louis, book a car rental, and secure great deals on resorts.

Frequently asked questions

Looking to vacation at a spa hotel in St. Louis?
Soothe the senses with some time in one of our wonderful spa hotels. Travelers love the fascinating museums and live music scene in St. Louis so get ready for a cultural tour. Hotels with spas are the perfect way to take a break from your daily routine and add a layer of luxury to your holiday.
What is the best spa hotel in St. Louis?
Ameristar Casino Resort and Spa (St. Charles) is a top luxury spa hotel featuring 7 restaurants, a casino, a nightclub, and an outdoor pool. Treat yourself to a facial, body scrub, or hydrotherapy at Ara. In-room massages are also available. Other popular spa hotels in St. Louis include Holiday Inn St Louis SW - Route 66 and The Ritz-Carlton, St. Louis.
How many spa hotels will I find in St. Louis?
Expedia has 79 spa hotels to choose from in St. Louis.
What's there to see and do in St. Louis?
Experience St. Louis and visit Enterprise Center, City Museum, and Busch Stadium. If you have spare time during your trip, you might want to make a stop at Dome at America’s Center and Chaifetz Arena.
What is a St. Louis spa hotel?
Spa hotels in St. Louis provide lodging and have an on-site spa offering services like couples massages and beauty treatments. Some also offer in-room treatments. Spa hotels are ideal if you are looking for some R&R during your vacation.

Travelers Loved These Resorts & Hotels with Spas

More trip options