Title: The Best 4 Star Hotels in Wayne, NE  | Expedia.com

[Wayne Travel Guide](https://expedia.com/Wayne.dx10311)[Hotels in Wayne](https://expedia.com/Wayne-Hotels.d10311.Travel-Guide-Hotels)[Vacation Rentals in Wayne](https://expedia.com/Wayne-Vacation-Rentals.d10311.Travel-Guide-VacationRentals)[Flights to Wayne](https://expedia.com/Cheap-Flights-To-Wayne.d10311.Travel-Guide-Flights)[Car Rentals in Wayne](https://expedia.com/Car-Rentals-In-Wayne.d10311.Car-Rental-Guide)[Wayne Vacation Packages](https://expedia.com/Wayne.d10311.Destination-Travel-Guides)

![First Presbyterian Church](https://images.trvl-media.com/place/10311/c1d3cbd7-a6f7-4ea8-9ea2-7f3de39083f5.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check availability on Wayne 4 Star Hotels

Tonight

[Feb 22 - Feb 23](https://www.expedia.com/Hotel-Search?regionId=10311&startDate=2026-02-22&endDate=2026-02-23&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Feb 23 - Feb 24](https://www.expedia.com/Hotel-Search?regionId=10311&startDate=2026-02-23&endDate=2026-02-24&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Feb 27 - Mar 1](https://www.expedia.com/Hotel-Search?regionId=10311&startDate=2026-02-27&endDate=2026-03-01&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two weeks

[Mar 6 - Mar 8](https://www.expedia.com/Hotel-Search?regionId=10311&startDate=2026-03-06&endDate=2026-03-08&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

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## Learn more about Wayne

Nestled around the historic Wayne County Courthouse, this charming college town invites visitors to explore local heritage at the Wayne County Museum. Take time to wander the Wayne State College campus or let your four-legged friends run free at Wayne Bark Park.

[See all hotels in Wayne](https://www.expedia.com/Hotel-Search?startDate=2026-03-08&endDate=2026-03-09&adults=2&regionId=10311)

![First Presbyterian Church](https://images.trvl-media.com/place/10311/c1d3cbd7-a6f7-4ea8-9ea2-7f3de39083f5.jpg?impolicy=fcrop&w=900&h=600&p=1&q=high)

## Top Wayne Hotel Reviews

## Find out more about Wayne

## Wayne Four Star Hotel Information

When you need to book a room with luxurious amazing amenities and the best rates, the 4 star hotels in Wayne, Nebraska are incredible options. Known for their extra perks, first-rate service, and fantastic locations, each of the Wayne 4 star hotels offers the ultimate experience for globe-trotting travelers. Relax in your expertly designed room. Kick back with around-the-clock room service.

Get a good night’s sleep with the ultra-plush bedding, and freshen up in the morning with designer-inspired body products. It’s all available when you stay at one of the top book a four star hotels in Wayne. What’s more, thanks to Expedia you might even score a cheap great deal on a 4 star hotel in Wayne, Nebraska, areas near the hottest attractions, so you can plan a sightseeing adventure and take advantage of unbeatable discounts in one fell swoop.

Whether you’re putting together a serene getaway or want to revel in the most vibrant entertainment district, 4 star Wayne hotels offer everything your heart desires.

## Frequently asked questions

### How much does it cost to stay in a 4-star hotel in Wayne?

> - Search for the lowest price

### What's the difference between 5-star and 4-star hotels in Wayne?

### Does Wayne have any 4-star all-inclusive resorts?

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- [Hotels near Wayne County Courthouse ](https://www.expedia.com/Wayne-County-Courthouse-Hotels.0-l6300994-0.Travel-Guide-Filter-Hotels)
- [Hotels near Wayne State College ](https://www.expedia.com/Wayne-State-College-Hotels.0-l6300999-0.Travel-Guide-Filter-Hotels)
- [Winside Hotels ](https://www.expedia.com/Winside-Hotels.d3000349815.Travel-Guide-Hotels)
- [Emerson Hotels ](https://www.expedia.com/Emerson-Hotels.d553248634983302101.Travel-Guide-Hotels)
- [Pilger Hotels ](https://www.expedia.com/Pilger-Hotels.d3000349790.Travel-Guide-Hotels)
- [Wisner Hotels ](https://www.expedia.com/Wisner-Hotels.d553248634983441980.Travel-Guide-Hotels)
- [Pender Hotels ](https://www.expedia.com/Pender-Hotels.d3000446311.Travel-Guide-Hotels)
- [Motels in Pender ](https://www.expedia.com/Pender-Motels.d3000446311-aaMotels.Travel-Guide-Accommodation)
- [Randolph Hotels ](https://www.expedia.com/Randolph-Hotels.d553248634983586917.Travel-Guide-Hotels)
- [Coleridge Hotels ](https://www.expedia.com/Coleridge-Hotels.d3000349751.Travel-Guide-Hotels)
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- [Visit Winside ](https://www.expedia.com/Winside.dx3000349815)
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- [Norfolk Arts Center ](https://www.expedia.com/Norfolk-Arts-Center-Norfolk.d553248621561875996.Vacation-Attraction)
- [Visit Norfolk ](https://www.expedia.com/Norfolk.dx2644)
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